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The map label for this gene is ndk [H]

Identifier: 158317026

GI number: 158317026

Start: 6339369

End: 6339782

Strand: Reverse

Name: ndk [H]

Synonym: Franean1_5270

Alternate gene names: 158317026

Gene position: 6339782-6339369 (Counterclockwise)

Preceding gene: 158317027

Following gene: 158317025

Centisome position: 70.58

GC content: 70.05

Gene sequence:

>414_bases
GTGTCCGCCGAGCGCACCCTCATCCTGGTCAAGCCCGATGGCGTCAGCCGCGGCCTCGTCGGTGAGGTCGTCGGCCGCAT
CGAGCGTAAGGGGCTGAAGATCGTCGCGCTCGAGCTGCGCACGCTTGAGCGCTCGGTCGCCGAGACCCATTACGGCGAGC
ACGCCAGCAAGCCGTTCTTCGGTGAGCTGGTGGAGTTCATTACCTCCGGCCCGCTCGTCGCGCTGGTGGCCGAGGGGCCC
CGCGCGGTCGAGGCGCTGCGCGGCCTGATCGGCGCCACCGACCCGGTGAAGGCGGCTCCCGGGTCGCTGCGCGGTGACTT
CGCGCTCGAGATCGGCCAGAACCTCATCCACGGTTCGGACTCGCCCGAGTCGGCCAAGCGCGAGATCGACCTCTTCTTCC
CCGGCCTGAGCTGA

Upstream 100 bases:

>100_bases
CCGACCCTGTAGGTTTGCCAGGGGCCAGCCGGTGTCGCGTAGACGCGGTCCGGGCGCCCTTACCACGTCGAAGATGACGA
AACGATTCTGAAGGAGTCCC

Downstream 100 bases:

>100_bases
CCCACCCGGCTCCGGCCGGCCCGTCCGAGGGTGGCCGGCGGCACCGTTGCGGGTGAACCGCCGGCCGCGCGGCGCCCCGT
CGCGGTGGCACCCCCGTGGG

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 137; Mature: 136

Protein sequence:

>137_residues
MSAERTLILVKPDGVSRGLVGEVVGRIERKGLKIVALELRTLERSVAETHYGEHASKPFFGELVEFITSGPLVALVAEGP
RAVEALRGLIGATDPVKAAPGSLRGDFALEIGQNLIHGSDSPESAKREIDLFFPGLS

Sequences:

>Translated_137_residues
MSAERTLILVKPDGVSRGLVGEVVGRIERKGLKIVALELRTLERSVAETHYGEHASKPFFGELVEFITSGPLVALVAEGP
RAVEALRGLIGATDPVKAAPGSLRGDFALEIGQNLIHGSDSPESAKREIDLFFPGLS
>Mature_136_residues
SAERTLILVKPDGVSRGLVGEVVGRIERKGLKIVALELRTLERSVAETHYGEHASKPFFGELVEFITSGPLVALVAEGPR
AVEALRGLIGATDPVKAAPGSLRGDFALEIGQNLIHGSDSPESAKREIDLFFPGLS

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI37693993, Length=130, Percent_Identity=56.1538461538462, Blast_Score=153, Evalue=4e-38,
Organism=Homo sapiens, GI4557797, Length=132, Percent_Identity=46.969696969697, Blast_Score=141, Evalue=2e-34,
Organism=Homo sapiens, GI38045913, Length=132, Percent_Identity=46.969696969697, Blast_Score=140, Evalue=3e-34,
Organism=Homo sapiens, GI4826862, Length=133, Percent_Identity=48.8721804511278, Blast_Score=138, Evalue=1e-33,
Organism=Homo sapiens, GI66392227, Length=132, Percent_Identity=46.2121212121212, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI66392205, Length=132, Percent_Identity=46.2121212121212, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI4505409, Length=132, Percent_Identity=46.2121212121212, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI66392192, Length=132, Percent_Identity=46.2121212121212, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI66392203, Length=132, Percent_Identity=46.2121212121212, Blast_Score=137, Evalue=3e-33,
Organism=Homo sapiens, GI37574614, Length=134, Percent_Identity=38.0597014925373, Blast_Score=91, Evalue=3e-19,
Organism=Homo sapiens, GI7019465, Length=135, Percent_Identity=37.7777777777778, Blast_Score=91, Evalue=4e-19,
Organism=Homo sapiens, GI5031951, Length=136, Percent_Identity=38.9705882352941, Blast_Score=86, Evalue=7e-18,
Organism=Homo sapiens, GI30023828, Length=145, Percent_Identity=35.1724137931034, Blast_Score=77, Evalue=3e-15,
Organism=Homo sapiens, GI4505413, Length=137, Percent_Identity=32.1167883211679, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1788866, Length=133, Percent_Identity=47.3684210526316, Blast_Score=125, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI17506807, Length=132, Percent_Identity=47.7272727272727, Blast_Score=144, Evalue=1e-35,
Organism=Saccharomyces cerevisiae, GI6322783, Length=132, Percent_Identity=50.7575757575758, Blast_Score=150, Evalue=6e-38,
Organism=Drosophila melanogaster, GI45549037, Length=132, Percent_Identity=48.4848484848485, Blast_Score=148, Evalue=1e-36,
Organism=Drosophila melanogaster, GI18860097, Length=134, Percent_Identity=29.8507462686567, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564
- InterPro:   IPR023005 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 14572; Mature: 14441

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAERTLILVKPDGVSRGLVGEVVGRIERKGLKIVALELRTLERSVAETHYGEHASKPFF
CCCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCCHH
GELVEFITSGPLVALVAEGPRAVEALRGLIGATDPVKAAPGSLRGDFALEIGQNLIHGSD
HHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
SPESAKREIDLFFPGLS
CCCHHHHEEEEECCCCC
>Mature Secondary Structure 
SAERTLILVKPDGVSRGLVGEVVGRIERKGLKIVALELRTLERSVAETHYGEHASKPFF
CCCCEEEEECCCCCCCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCCCCHH
GELVEFITSGPLVALVAEGPRAVEALRGLIGATDPVKAAPGSLRGDFALEIGQNLIHGSD
HHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
SPESAKREIDLFFPGLS
CCCHHHHEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA