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The map label for this gene is yhjK [C]

Identifier: 157962874

GI number: 157962874

Start: 3749052

End: 3751091

Strand: Direct

Name: yhjK [C]

Synonym: Spea_3056

Alternate gene names: 157962874

Gene position: 3749052-3751091 (Clockwise)

Preceding gene: 157962862

Following gene: 157962887

Centisome position: 72.45

GC content: 44.71

Gene sequence:

>2040_bases
ATGGACAGTTTCAAATCACTGACATGGAAGCAGACTATCTTAGTGGTTTCTTCCACACTTTTTTTCGCCGTTGTGATCTT
TTTTATTGAGATATCTCTCCTCGTTATCGATGCTCGCCAAGAGCTTTCGGAAAGCCAACAAGAACTCGTCGACTCAGTTG
AACAGCCAGCGACCAATGCGATCTGGGCATTAGATGATTTACGTGCTGAACAAACCATTCAAGGGATCTTAAAAGTAGAG
CATGTAGGCTCGGCGATATTAAAACTTGAAGATGGTAGCCGTTTCGTATCAGTTAATAATGGTGCCCCATCCGTTAATCC
TGAGCTTTTTACCTCAATCAGTGCCAAACTCTTTGGCGACCTAAAACAGATCTCTCGCTCGCTGTACCGCCCTTTTTATA
CCGATGCTAATGGTAATAAAGAACTTATCGGCAGCCTAACCGTTTTCTATTACACTCAAGAGCTAACCAGCTCTTTATTT
TCTAGCCTTAGATTCAGCCTTTGGGCAACTCTTGCGAGAGCCTTCCTGCTAACGCTTGTTCTGTCTATTGTGTTCCATCG
TTTTCTTACCCAGCCGATAGCGAAAATAAGCGAAGCTATCGACAGAATCGATCCCGAATCCCCTGCGAATCACTTGCTTC
CACCTGACCGTGCTCATAATGATGACGAACTCGGGGCGGTTATCTCCAAGCTCAATCAGATCTTGATTCAATTCGACACG
ACTCAGACTAAGCTACGCAAGATGGCGACACGGGACCCCCTGACTGAATTGCCTAATCGCACTTTATTGCTTGAAACTAT
TGCGGTTACCATCCAAAGAGCAAAGACCAAACAGAGACGTTTCAGCTTGCTGTTCATTGACCTAGACCGTTTTAAAAACG
TTAACGATTCATTGGGACATGAAGTTGGCGACCAATTTTTAATACGAGTCGCGCGTAACCTAGAGTTAACCGTTGGCCAG
ATAGGTACGGTCGCAAGGCTTGGAGGCGATGAATTTGTGGTATTAGCGGATGGTTTAGACTCCCCCACAAAAGCGGTCGA
GTTGGTCGATAAGTTACTGGTTCAACTGAACACGCCTATGCAACTCAATGAGCATACTGTGCACCCTGCAGCCTCAATCG
GTATCGCAATCTATCCCGATGACGGCCTTCGAGCCGAAGACCTTATTCGCCATGCCGATATCGCCATGTACAGCGCAAAA
GCCGCTGGCTCAAACCAATGGGCATTCTTTAAACCTCAAATGACCGAACGTGCTTCAGTACGTTTAAGAACTGAGGCTTC
GTTACATGATGCGCTTGAGAACAATGAATTCATATTACATTTTCAGCCAAAACTAGATATAGAAACCGGTGCAGTGGTTG
GTTGCGAAGCCCTTATCCGCTGGCAAAAGGATGGCCGTTTAATAAGTCCAGCCTCTTTTATTCCTGTGGCGGAAGAAACT
GGTATGATTATTCAAATAGGCCAATGGGTTGTCGAGCAAAGTTGCAAAACCATCAAAGACTGGAAAACTCGCTATAACTT
TTCGGTGCCAATTGCCATTAATGTCTCATCACAGCAGTTTTTAGATGCCAGCCTAGTCCCCGATATAAAACAGGCGGCAC
TGCGTTATCAAGTAGCTCCTCAATCACTGGAAATAGAGATCACTGAAACTTCTCTGATGAATGACATAGAGTCCGCAATT
ATAAAGCTTCAACAGTTAAAGTCCGCAGGTTTTGGCATTGCTGTAGACGATTTTGGTACAGGTTATTCTTCTCTTTCTTA
CCTACGGCGTCTGCCAATAAGCACCATGAAGATTGATCGTGGTTTTGTATCTGATCTGCCTGAAGAGAGTGCAATCGCAT
CGACTATTTTAATGCTTGGCAAGCAACTTGATTTAAACATTGTCGCCGAGGGAGTTGAGAATGAGCAGCAGCTTGCTTGG
TTACAAAACCAAGGCTGTCAGATAGGACAAGGGTTTTACTTTAGTAAGCCTCTACCAATAGAATCGTTTGAAGCCAAGTA
CATTGCTCCAAATCGTAACACCATAAAAACCAGCAGCTAG

Upstream 100 bases:

>100_bases
CCCTAAAGTGGACGCATTAGCCATAAAACACCTAATCCACGCCAATATCTCTAGCAATAAAAAAAAACTAAGCCATTGAA
ATAAGGGGATAGAGTTAAAG

Downstream 100 bases:

>100_bases
CATTCCTCCCCTACTGTTGAGAGACATTAGCTGAGCTTAGTAACCACCTTACGTGCAGTTAGTAAAACCGTGCGCATATT
TATACTGATTGGTATTACTT

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 679; Mature: 679

Protein sequence:

>679_residues
MDSFKSLTWKQTILVVSSTLFFAVVIFFIEISLLVIDARQELSESQQELVDSVEQPATNAIWALDDLRAEQTIQGILKVE
HVGSAILKLEDGSRFVSVNNGAPSVNPELFTSISAKLFGDLKQISRSLYRPFYTDANGNKELIGSLTVFYYTQELTSSLF
SSLRFSLWATLARAFLLTLVLSIVFHRFLTQPIAKISEAIDRIDPESPANHLLPPDRAHNDDELGAVISKLNQILIQFDT
TQTKLRKMATRDPLTELPNRTLLLETIAVTIQRAKTKQRRFSLLFIDLDRFKNVNDSLGHEVGDQFLIRVARNLELTVGQ
IGTVARLGGDEFVVLADGLDSPTKAVELVDKLLVQLNTPMQLNEHTVHPAASIGIAIYPDDGLRAEDLIRHADIAMYSAK
AAGSNQWAFFKPQMTERASVRLRTEASLHDALENNEFILHFQPKLDIETGAVVGCEALIRWQKDGRLISPASFIPVAEET
GMIIQIGQWVVEQSCKTIKDWKTRYNFSVPIAINVSSQQFLDASLVPDIKQAALRYQVAPQSLEIEITETSLMNDIESAI
IKLQQLKSAGFGIAVDDFGTGYSSLSYLRRLPISTMKIDRGFVSDLPEESAIASTILMLGKQLDLNIVAEGVENEQQLAW
LQNQGCQIGQGFYFSKPLPIESFEAKYIAPNRNTIKTSS

Sequences:

>Translated_679_residues
MDSFKSLTWKQTILVVSSTLFFAVVIFFIEISLLVIDARQELSESQQELVDSVEQPATNAIWALDDLRAEQTIQGILKVE
HVGSAILKLEDGSRFVSVNNGAPSVNPELFTSISAKLFGDLKQISRSLYRPFYTDANGNKELIGSLTVFYYTQELTSSLF
SSLRFSLWATLARAFLLTLVLSIVFHRFLTQPIAKISEAIDRIDPESPANHLLPPDRAHNDDELGAVISKLNQILIQFDT
TQTKLRKMATRDPLTELPNRTLLLETIAVTIQRAKTKQRRFSLLFIDLDRFKNVNDSLGHEVGDQFLIRVARNLELTVGQ
IGTVARLGGDEFVVLADGLDSPTKAVELVDKLLVQLNTPMQLNEHTVHPAASIGIAIYPDDGLRAEDLIRHADIAMYSAK
AAGSNQWAFFKPQMTERASVRLRTEASLHDALENNEFILHFQPKLDIETGAVVGCEALIRWQKDGRLISPASFIPVAEET
GMIIQIGQWVVEQSCKTIKDWKTRYNFSVPIAINVSSQQFLDASLVPDIKQAALRYQVAPQSLEIEITETSLMNDIESAI
IKLQQLKSAGFGIAVDDFGTGYSSLSYLRRLPISTMKIDRGFVSDLPEESAIASTILMLGKQLDLNIVAEGVENEQQLAW
LQNQGCQIGQGFYFSKPLPIESFEAKYIAPNRNTIKTSS
>Mature_679_residues
MDSFKSLTWKQTILVVSSTLFFAVVIFFIEISLLVIDARQELSESQQELVDSVEQPATNAIWALDDLRAEQTIQGILKVE
HVGSAILKLEDGSRFVSVNNGAPSVNPELFTSISAKLFGDLKQISRSLYRPFYTDANGNKELIGSLTVFYYTQELTSSLF
SSLRFSLWATLARAFLLTLVLSIVFHRFLTQPIAKISEAIDRIDPESPANHLLPPDRAHNDDELGAVISKLNQILIQFDT
TQTKLRKMATRDPLTELPNRTLLLETIAVTIQRAKTKQRRFSLLFIDLDRFKNVNDSLGHEVGDQFLIRVARNLELTVGQ
IGTVARLGGDEFVVLADGLDSPTKAVELVDKLLVQLNTPMQLNEHTVHPAASIGIAIYPDDGLRAEDLIRHADIAMYSAK
AAGSNQWAFFKPQMTERASVRLRTEASLHDALENNEFILHFQPKLDIETGAVVGCEALIRWQKDGRLISPASFIPVAEET
GMIIQIGQWVVEQSCKTIKDWKTRYNFSVPIAINVSSQQFLDASLVPDIKQAALRYQVAPQSLEIEITETSLMNDIESAI
IKLQQLKSAGFGIAVDDFGTGYSSLSYLRRLPISTMKIDRGFVSDLPEESAIASTILMLGKQLDLNIVAEGVENEQQLAW
LQNQGCQIGQGFYFSKPLPIESFEAKYIAPNRNTIKTSS

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI226510982, Length=677, Percent_Identity=30.1329394387001, Blast_Score=304, Evalue=1e-83,
Organism=Escherichia coli, GI1787541, Length=433, Percent_Identity=36.7205542725173, Blast_Score=288, Evalue=7e-79,
Organism=Escherichia coli, GI87081921, Length=429, Percent_Identity=32.4009324009324, Blast_Score=231, Evalue=1e-61,
Organism=Escherichia coli, GI1790496, Length=250, Percent_Identity=36, Blast_Score=171, Evalue=2e-43,
Organism=Escherichia coli, GI87081743, Length=237, Percent_Identity=38.3966244725738, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI87081845, Length=238, Percent_Identity=36.5546218487395, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI1788502, Length=249, Percent_Identity=32.5301204819277, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI87081980, Length=256, Percent_Identity=31.640625, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1786507, Length=272, Percent_Identity=30.5147058823529, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1788849, Length=262, Percent_Identity=31.6793893129771, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1787055, Length=242, Percent_Identity=30.5785123966942, Blast_Score=118, Evalue=2e-27,
Organism=Escherichia coli, GI87082096, Length=437, Percent_Identity=24.9427917620137, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1788381, Length=371, Percent_Identity=26.4150943396226, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786584, Length=165, Percent_Identity=31.5151515151515, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1787262, Length=186, Percent_Identity=31.1827956989247, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI87081977, Length=152, Percent_Identity=36.8421052631579, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87082007, Length=168, Percent_Identity=33.9285714285714, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788956, Length=179, Percent_Identity=30.7262569832402, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787802, Length=196, Percent_Identity=29.0816326530612, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI145693134, Length=167, Percent_Identity=32.9341317365269, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787816, Length=169, Percent_Identity=30.1775147928994, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081881, Length=180, Percent_Identity=31.6666666666667, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789650, Length=450, Percent_Identity=20.6666666666667, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1787410, Length=135, Percent_Identity=27.4074074074074, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 75648; Mature: 75648

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSFKSLTWKQTILVVSSTLFFAVVIFFIEISLLVIDARQELSESQQELVDSVEQPATNA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCCCCC
IWALDDLRAEQTIQGILKVEHVGSAILKLEDGSRFVSVNNGAPSVNPELFTSISAKLFGD
EEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHH
LKQISRSLYRPFYTDANGNKELIGSLTVFYYTQELTSSLFSSLRFSLWATLARAFLLTLV
HHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSIVFHRFLTQPIAKISEAIDRIDPESPANHLLPPDRAHNDDELGAVISKLNQILIQFDT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECC
TQTKLRKMATRDPLTELPNRTLLLETIAVTIQRAKTKQRRFSLLFIDLDRFKNVNDSLGH
HHHHHHHHHHCCCHHHCCCCEEHHHHHHHHHHHHHHHHHEEEEEEEEHHHCCCCCHHHHH
EVGDQFLIRVARNLELTVGQIGTVARLGGDEFVVLADGLDSPTKAVELVDKLLVQLNTPM
HHHHHHHHHHHHCCEEEECCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
QLNEHTVHPAASIGIAIYPDDGLRAEDLIRHADIAMYSAKAAGSNQWAFFKPQMTERASV
CCCCCCCCCHHHCEEEEECCCCCCHHHHHHHHHHHHEEECCCCCCCEEEECCCCCCCCCE
RLRTEASLHDALENNEFILHFQPKLDIETGAVVGCEALIRWQKDGRLISPASFIPVAEET
EEEEHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHEECCCCCEECCCCCCCCCCCC
GMIIQIGQWVVEQSCKTIKDWKTRYNFSVPIAINVSSQQFLDASLVPDIKQAALRYQVAP
CCEEEHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHCHHCCCHHHHHHHHHEECC
QSLEIEITETSLMNDIESAIIKLQQLKSAGFGIAVDDFGTGYSSLSYLRRLPISTMKIDR
CCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCEEECC
GFVSDLPEESAIASTILMLGKQLDLNIVAEGVENEQQLAWLQNQGCQIGQGFYFSKPLPI
CHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCEECCCEEECCCCCC
ESFEAKYIAPNRNTIKTSS
CCCCCEEECCCCCCCCCCC
>Mature Secondary Structure
MDSFKSLTWKQTILVVSSTLFFAVVIFFIEISLLVIDARQELSESQQELVDSVEQPATNA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHCCCCCC
IWALDDLRAEQTIQGILKVEHVGSAILKLEDGSRFVSVNNGAPSVNPELFTSISAKLFGD
EEEHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEEECCCCCCCCHHHHHHHHHHHHHH
LKQISRSLYRPFYTDANGNKELIGSLTVFYYTQELTSSLFSSLRFSLWATLARAFLLTLV
HHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSIVFHRFLTQPIAKISEAIDRIDPESPANHLLPPDRAHNDDELGAVISKLNQILIQFDT
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECC
TQTKLRKMATRDPLTELPNRTLLLETIAVTIQRAKTKQRRFSLLFIDLDRFKNVNDSLGH
HHHHHHHHHHCCCHHHCCCCEEHHHHHHHHHHHHHHHHHEEEEEEEEHHHCCCCCHHHHH
EVGDQFLIRVARNLELTVGQIGTVARLGGDEFVVLADGLDSPTKAVELVDKLLVQLNTPM
HHHHHHHHHHHHCCEEEECCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCC
QLNEHTVHPAASIGIAIYPDDGLRAEDLIRHADIAMYSAKAAGSNQWAFFKPQMTERASV
CCCCCCCCCHHHCEEEEECCCCCCHHHHHHHHHHHHEEECCCCCCCEEEECCCCCCCCCE
RLRTEASLHDALENNEFILHFQPKLDIETGAVVGCEALIRWQKDGRLISPASFIPVAEET
EEEEHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHEECCCCCEECCCCCCCCCCCC
GMIIQIGQWVVEQSCKTIKDWKTRYNFSVPIAINVSSQQFLDASLVPDIKQAALRYQVAP
CCEEEHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCHHHHHCHHCCCHHHHHHHHHEECC
QSLEIEITETSLMNDIESAIIKLQQLKSAGFGIAVDDFGTGYSSLSYLRRLPISTMKIDR
CCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCEEECC
GFVSDLPEESAIASTILMLGKQLDLNIVAEGVENEQQLAWLQNQGCQIGQGFYFSKPLPI
CHHHCCCCHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHCCCEECCCEEECCCCCC
ESFEAKYIAPNRNTIKTSS
CCCCCEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]