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The map label for this gene is lpsI [H]

Identifier: 157962623

GI number: 157962623

Start: 3423121

End: 3423855

Strand: Direct

Name: lpsI [H]

Synonym: Spea_2803

Alternate gene names: 157962623

Gene position: 3423121-3423855 (Clockwise)

Preceding gene: 157962622

Following gene: 157962624

Centisome position: 66.15

GC content: 47.76

Gene sequence:

>735_bases
ATGACAGGACTAAATAAGGTTGTTGCAAGTTACGATGAGGCACTCGCAGGCCTAAGCAACGATATGACAGTAATGGTCGG
CGGCTTTGGCTTGTGTGGTATTCCTGAGGGCTTAATCGCGCAAATGGTCAAATCCGGTGTAACAGGATTAACCGCCATCT
CAAATAATGCTGGCGTCGATGACTTTGGTTTAGGCCTGCTATTAAAGAGCCGCCAAATCGATACCATGATCGCTTCTTAC
GTAGGTGAAAATGCCACCTTCGAACAGCAGATGTTATCAGGTGAGCTTAACGTTATCTTGACACCTCAAGGCACCTTGGC
AGAGAAAATTCGTGCCGGCGGTGCTGGTATTCCAGCATTCTTTACCGCTACAGGTTACGGCACGCCTGTCGCGGAAGGTA
AAGAGACCCGTGAAATTGATGGCCGTCACTATGTGTTAGAGCCAGCGTTAAAAGCAGACTTTGCGCTAGTACGAGCTTGG
AAAGCTGACACCATGGGCAACTTGGTGTTCCGTAAAACTGCGGCCAACTTTAACCCTATGATGGCCACAGCTGGTAAAAT
TACCGTGGTAGAGGCTGAACATATTGTTGAGCCGGGAGAGCTCGACCCTGACCATATCCATACACCTGGCATTTACGTTA
ATCGCGTGATCCAAGGTAAGTTCGAGAAACGTATCGAGCAACGTACTGTTAAACCGGTCTCTGATTCAAATACAAACTCA
GATGCAAAAGCATAA

Upstream 100 bases:

>100_bases
TTAATAAAGAGCGATTAGCAAATAAGAAATAGACTCTGAACCTAGGACCTAGGATCTAGGACCTAGGACCTAGCATTGAC
AGAATATGGAGATAACAAAA

Downstream 100 bases:

>100_bases
GGAGGCAGCACCATGGCATTATCAAGAGAACAACTGGCACAGCGTGTAGCACAAGAACTCCAAGATGGCTTTTACGTCAA
CCTAGGCATTGGTATTCCAA

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MTGLNKVVASYDEALAGLSNDMTVMVGGFGLCGIPEGLIAQMVKSGVTGLTAISNNAGVDDFGLGLLLKSRQIDTMIASY
VGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIDGRHYVLEPALKADFALVRAW
KADTMGNLVFRKTAANFNPMMATAGKITVVEAEHIVEPGELDPDHIHTPGIYVNRVIQGKFEKRIEQRTVKPVSDSNTNS
DAKA

Sequences:

>Translated_244_residues
MTGLNKVVASYDEALAGLSNDMTVMVGGFGLCGIPEGLIAQMVKSGVTGLTAISNNAGVDDFGLGLLLKSRQIDTMIASY
VGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIDGRHYVLEPALKADFALVRAW
KADTMGNLVFRKTAANFNPMMATAGKITVVEAEHIVEPGELDPDHIHTPGIYVNRVIQGKFEKRIEQRTVKPVSDSNTNS
DAKA
>Mature_243_residues
TGLNKVVASYDEALAGLSNDMTVMVGGFGLCGIPEGLIAQMVKSGVTGLTAISNNAGVDDFGLGLLLKSRQIDTMIASYV
GENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAFFTATGYGTPVAEGKETREIDGRHYVLEPALKADFALVRAWK
ADTMGNLVFRKTAANFNPMMATAGKITVVEAEHIVEPGELDPDHIHTPGIYVNRVIQGKFEKRIEQRTVKPVSDSNTNSD
AKA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=57.085020242915, Blast_Score=283, Evalue=7e-77,
Organism=Homo sapiens, GI11545841, Length=258, Percent_Identity=51.5503875968992, Blast_Score=249, Evalue=1e-66,
Organism=Escherichia coli, GI1788551, Length=216, Percent_Identity=44.9074074074074, Blast_Score=197, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17531517, Length=243, Percent_Identity=52.6748971193416, Blast_Score=261, Evalue=2e-70,
Organism=Drosophila melanogaster, GI21358325, Length=247, Percent_Identity=50.6072874493927, Blast_Score=242, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24655794, Length=247, Percent_Identity=50.6072874493927, Blast_Score=242, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25944; Mature: 25813

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLNKVVASYDEALAGLSNDMTVMVGGFGLCGIPEGLIAQMVKSGVTGLTAISNNAGVD
CCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCC
DFGLGLLLKSRQIDTMIASYVGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAF
CHHHHHEECCHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCE
FTATGYGTPVAEGKETREIDGRHYVLEPALKADFALVRAWKADTMGNLVFRKTAANFNPM
EEECCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
MATAGKITVVEAEHIVEPGELDPDHIHTPGIYVNRVIQGKFEKRIEQRTVKPVSDSNTNS
EECCCEEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DAKA
CCCC
>Mature Secondary Structure 
TGLNKVVASYDEALAGLSNDMTVMVGGFGLCGIPEGLIAQMVKSGVTGLTAISNNAGVD
CCHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCC
DFGLGLLLKSRQIDTMIASYVGENATFEQQMLSGELNVILTPQGTLAEKIRAGGAGIPAF
CHHHHHEECCHHHHHHHHHHHCCCCHHHHHHHCCCCEEEECCCCHHHHHHHCCCCCCCCE
FTATGYGTPVAEGKETREIDGRHYVLEPALKADFALVRAWKADTMGNLVFRKTAANFNPM
EEECCCCCCCCCCCCCCCCCCCEEEECCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCC
MATAGKITVVEAEHIVEPGELDPDHIHTPGIYVNRVIQGKFEKRIEQRTVKPVSDSNTNS
EECCCEEEEEEHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
DAKA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]