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The map label for this gene is clpX [H]

Identifier: 157962501

GI number: 157962501

Start: 3266237

End: 3267514

Strand: Reverse

Name: clpX [H]

Synonym: Spea_2680

Alternate gene names: 157962501

Gene position: 3267514-3266237 (Counterclockwise)

Preceding gene: 157962502

Following gene: 157962500

Centisome position: 63.15

GC content: 44.91

Gene sequence:

>1278_bases
ATGGGTGAAGACAAAGGTAACGGTGACGGCGGAAAGCTGCTGTACTGCTCTTTTTGTGGCAAGAGCCAGCATGAGGTAAG
AAAACTCATTGCTGGGCCTTCTGTATATGTTTGTGATGAGTGTGTTGAACTCTGCAATGACATCATTAGAGAAGAGATTA
AAGAGATCTCGCCAAAGCAAGATCAAGACAAGTTGCCTACGCCTCATGAGCTAAGAGCACACTTGGATGATTATGTTATC
GGTCAAGATAAAGCTAAGAAGGTTCTTGCTGTTGCGGTGTATAACCACTACAAGCGCCTTAGAAATGCTAGCCCTAAAGA
TGGCGTAGAACTTGGCAAGAGTAACATCTTGCTAATTGGCCCAACGGGTAGTGGTAAAACCTTATTAGCAGAAACGCTTG
CACGTGTTCTTGATGTGCCATTTACTATGGCTGATGCAACCACGCTTACCGAAGCGGGTTACGTTGGTGAAGATGTTGAG
AACATCATTCAAAAGCTACTGCAAAAGTGTGACTACGACGTTGAAAAAGCGCAGCGCGGTATCGTGTATATCGATGAAAT
TGATAAAATCAGTCGTAAGTCTGATAATCCATCAATCACACGTGACGTATCGGGTGAGGGTGTTCAGCAAGCGTTGTTGA
AACTGATCGAAGGTACTATCGCTGCCGTGCCACCACAAGGTGGTCGTAAGCACCCTCAACAGGAGTTCTTACAGGTCGAT
ACCTCTAAGATCTTGTTCGTTTGTGGTGGTGCATTCGCAGGTCTTGAAAAAGTGATTGAGCAACGCGCTCATGTCGGTAC
TGGTATTGGTTTTGGCGCCCAAGTCAAAGGTGAAGCTGATAAGAAGACTATCTCTGATACACTGTTAGAAGTGGAACCAG
AAGATTTAGTTAAGTTTGGTTTGATCCCTGAGTTTATTGGCCGTCTACCAGTACTTGCGACACTGTCAGAACTTGACGAT
GAAGCCTTGATTCAGATCCTGTCTGAACCAAAGAATGCGATTACTAAACAGTTTGCAGCATTGTTTGAGATGGAAAATGT
AGAGCTTGAGTTTAGAGACGATGCGTTAAAGGCGATAGCCCTTAAAGCACAAACCCGTAAAACGGGTGCTCGTGGTCTTC
GCTCTATCGTTGAAGGGATCTTACTCGATATCATGTATGATCTACCATCGACTGATGATGTGGCTAAGGTTGTTATCGAC
GAGTCAGTGGTTAAAGGCGAATCTAGCCCAATCTTGATCTACGCTAATAACGAAGCACAAACCGCCACGGCGGAGTAA

Upstream 100 bases:

>100_bases
AGCAAAACGAGGCTGATTTTTACTTCGCTCTGAGCTATGCTCAAATATGAAGTAACGATAAGATTTAGGCAGTAGAATTG
CTGCAAACAGAGGTAAAGTA

Downstream 100 bases:

>100_bases
TTTCTCGTCTAAAGTCAGACTGTGAGTTTAAAAGGAGCCAATATGGCTCCTTTTTTATGCAGTTCTCCAATTTATTTATT
TTCGCCATTGAAACCTATTT

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MGEDKGNGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQDQDKLPTPHELRAHLDDYVI
GQDKAKKVLAVAVYNHYKRLRNASPKDGVELGKSNILLIGPTGSGKTLLAETLARVLDVPFTMADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVD
TSKILFVCGGAFAGLEKVIEQRAHVGTGIGFGAQVKGEADKKTISDTLLEVEPEDLVKFGLIPEFIGRLPVLATLSELDD
EALIQILSEPKNAITKQFAALFEMENVELEFRDDALKAIALKAQTRKTGARGLRSIVEGILLDIMYDLPSTDDVAKVVID
ESVVKGESSPILIYANNEAQTATAE

Sequences:

>Translated_425_residues
MGEDKGNGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQDQDKLPTPHELRAHLDDYVI
GQDKAKKVLAVAVYNHYKRLRNASPKDGVELGKSNILLIGPTGSGKTLLAETLARVLDVPFTMADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVD
TSKILFVCGGAFAGLEKVIEQRAHVGTGIGFGAQVKGEADKKTISDTLLEVEPEDLVKFGLIPEFIGRLPVLATLSELDD
EALIQILSEPKNAITKQFAALFEMENVELEFRDDALKAIALKAQTRKTGARGLRSIVEGILLDIMYDLPSTDDVAKVVID
ESVVKGESSPILIYANNEAQTATAE
>Mature_424_residues
GEDKGNGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQDQDKLPTPHELRAHLDDYVIG
QDKAKKVLAVAVYNHYKRLRNASPKDGVELGKSNILLIGPTGSGKTLLAETLARVLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVDT
SKILFVCGGAFAGLEKVIEQRAHVGTGIGFGAQVKGEADKKTISDTLLEVEPEDLVKFGLIPEFIGRLPVLATLSELDDE
ALIQILSEPKNAITKQFAALFEMENVELEFRDDALKAIALKAQTRKTGARGLRSIVEGILLDIMYDLPSTDDVAKVVIDE
SVVKGESSPILIYANNEAQTATAE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=335, Percent_Identity=52.2388059701493, Blast_Score=308, Evalue=5e-84,
Organism=Escherichia coli, GI1786642, Length=422, Percent_Identity=80.5687203791469, Blast_Score=703, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=101, Percent_Identity=44.5544554455446, Blast_Score=92, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=327, Percent_Identity=43.7308868501529, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI71982905, Length=327, Percent_Identity=43.7308868501529, Blast_Score=259, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI71988663, Length=394, Percent_Identity=39.3401015228426, Blast_Score=246, Evalue=2e-65,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=41.7004048582996, Blast_Score=176, Evalue=3e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=424, Percent_Identity=39.3867924528302, Blast_Score=264, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24648291, Length=317, Percent_Identity=47.6340694006309, Blast_Score=284, Evalue=8e-77,
Organism=Drosophila melanogaster, GI24648289, Length=317, Percent_Identity=47.6340694006309, Blast_Score=284, Evalue=8e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46330; Mature: 46199

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEDKGNGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQ
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DQDKLPTPHELRAHLDDYVIGQDKAKKVLAVAVYNHYKRLRNASPKDGVELGKSNILLIG
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEE
PTGSGKTLLAETLARVLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRG
CCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCC
IVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVD
EEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHEECCCCCCCCCCHHHHHHHC
TSKILFVCGGAFAGLEKVIEQRAHVGTGIGFGAQVKGEADKKTISDTLLEVEPEDLVKFG
CCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHC
LIPEFIGRLPVLATLSELDDEALIQILSEPKNAITKQFAALFEMENVELEFRDDALKAIA
CHHHHHCCCHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHH
LKAQTRKTGARGLRSIVEGILLDIMYDLPSTDDVAKVVIDESVVKGESSPILIYANNEAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
TATAE
CCCCC
>Mature Secondary Structure 
GEDKGNGDGGKLLYCSFCGKSQHEVRKLIAGPSVYVCDECVELCNDIIREEIKEISPKQ
CCCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
DQDKLPTPHELRAHLDDYVIGQDKAKKVLAVAVYNHYKRLRNASPKDGVELGKSNILLIG
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEE
PTGSGKTLLAETLARVLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQRG
CCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCC
IVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTIAAVPPQGGRKHPQQEFLQVD
EEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCHHEECCCCCCCCCCHHHHHHHC
TSKILFVCGGAFAGLEKVIEQRAHVGTGIGFGAQVKGEADKKTISDTLLEVEPEDLVKFG
CCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHC
LIPEFIGRLPVLATLSELDDEALIQILSEPKNAITKQFAALFEMENVELEFRDDALKAIA
CHHHHHCCCHHHHHHHHCCHHHHHHHHHCHHHHHHHHHHHHHHHCCCEEEECHHHHHHHH
LKAQTRKTGARGLRSIVEGILLDIMYDLPSTDDVAKVVIDESVVKGESSPILIYANNEAQ
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCC
TATAE
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA