Click here to switch to the map view.

The map label for this gene is purC [H]

Identifier: 157962285

GI number: 157962285

Start: 3007082

End: 3008185

Strand: Direct

Name: purC [H]

Synonym: Spea_2464

Alternate gene names: 157962285

Gene position: 3007082-3008185 (Clockwise)

Preceding gene: 157962284

Following gene: 157962286

Centisome position: 58.11

GC content: 43.84

Gene sequence:

>1104_bases
ATGAATCTTGCAGATAAAGTTTTAGTCGTAAATGACAACCTCCCAATTCGTACCGACAAACCTGTTCACTCAGGCAAGGT
CCGCAGTGTTTACTGGTTAACCGAAGAAGATAGCGCTCGGTTAATTAAAGATAAAGGTTACGATGTACCAGCCGATGCTC
CACTTGCCATTATGGTGATCAGTGACCGTATCTCAGCATTTGATTGCGTATGGCAAGGTGAAAATGGCTTAAATGGCGTT
CCTGGTAAAGGTACGGCGCTTAATGCCATCTCAAATCACTGGTTTAAACTTTTCAAAGACAAGGGGCTTGCCGATAGCCA
TATCCTTGATATCCCTCACCCACTCGTATGGATAGTGCAAAAAGCCCGTCCGGTGATGATTGAAGCCATTGCACGCCAGT
ACATTACTGGCTCAATGTGGCGTTCATACACCAAAGGTGAGCGTGAGTTCTGTGGTATTACTATCCCTGAAGGCCTAGAG
AAAGATCAGAAACTCCCAGAACTGCTGATCACACCATCGACTAAAGGTGTATTAACGGGTCTTGAAGGCGTGCCTGAAGC
TGATGATGTAAACGTATCGCGCAGCGACATTGAGCGCCACGTTAAAGGCTTTAATTTCAGTAATGAGTCTGATATCGATC
TTTACGAGAAACTGCTTAAAGAAGGCTTTGACGTGATTAGCGACGCACTGGCTGAGCACGATCAGATTTTTGTCGATACC
AAGTTTGAGTTTGGCTATGTCAATGATGCTGCTGGTAATGAAAAGCTCATTTATATGGATGAAGTGGGTACGCCAGATAG
CTCTCGTATTTGGGATGGTTCATCGCACCGTGATGGTAAGATCATCGAGCAATCTAAAGAAGGCTTTAGACAATGGCTAC
TTAATCACTTCCCAGATCCAGATATCTTGTTAAACAAAAATCGCATGGTGGAGCGTTTCGCACTTGCAAGTGATAACAAG
TTACCAGAATCTGTGATGATGGATATCTCTAATACTTATGTGGGTATTGCTGAGAAGATCATCGGCAAGAAGCTGCATAT
CAGTGACAATCCTAAGCAGGAAATCATCGATATCTTGCGCGACGAGTATCAACTTATCGTTTAA

Upstream 100 bases:

>100_bases
ACAAAGAGTAAAATCCTCGTTGTCCTAGTGTTGCAACCCACAACTTCTGTTACAATCTGCGCCACTAAAATTAAGCTTCT
CAATAATAAAAGTGTGCCCT

Downstream 100 bases:

>100_bases
TCGATGAGAAGACAATTGTAATAAAAAAGCCGCAATATCAATTGCGGCTTTTTTATTAATCATGTCTTGTCCTGAAATGT
GTTTACACATTTAGGACTTT

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MNLADKVLVVNDNLPIRTDKPVHSGKVRSVYWLTEEDSARLIKDKGYDVPADAPLAIMVISDRISAFDCVWQGENGLNGV
PGKGTALNAISNHWFKLFKDKGLADSHILDIPHPLVWIVQKARPVMIEAIARQYITGSMWRSYTKGEREFCGITIPEGLE
KDQKLPELLITPSTKGVLTGLEGVPEADDVNVSRSDIERHVKGFNFSNESDIDLYEKLLKEGFDVISDALAEHDQIFVDT
KFEFGYVNDAAGNEKLIYMDEVGTPDSSRIWDGSSHRDGKIIEQSKEGFRQWLLNHFPDPDILLNKNRMVERFALASDNK
LPESVMMDISNTYVGIAEKIIGKKLHISDNPKQEIIDILRDEYQLIV

Sequences:

>Translated_367_residues
MNLADKVLVVNDNLPIRTDKPVHSGKVRSVYWLTEEDSARLIKDKGYDVPADAPLAIMVISDRISAFDCVWQGENGLNGV
PGKGTALNAISNHWFKLFKDKGLADSHILDIPHPLVWIVQKARPVMIEAIARQYITGSMWRSYTKGEREFCGITIPEGLE
KDQKLPELLITPSTKGVLTGLEGVPEADDVNVSRSDIERHVKGFNFSNESDIDLYEKLLKEGFDVISDALAEHDQIFVDT
KFEFGYVNDAAGNEKLIYMDEVGTPDSSRIWDGSSHRDGKIIEQSKEGFRQWLLNHFPDPDILLNKNRMVERFALASDNK
LPESVMMDISNTYVGIAEKIIGKKLHISDNPKQEIIDILRDEYQLIV
>Mature_367_residues
MNLADKVLVVNDNLPIRTDKPVHSGKVRSVYWLTEEDSARLIKDKGYDVPADAPLAIMVISDRISAFDCVWQGENGLNGV
PGKGTALNAISNHWFKLFKDKGLADSHILDIPHPLVWIVQKARPVMIEAIARQYITGSMWRSYTKGEREFCGITIPEGLE
KDQKLPELLITPSTKGVLTGLEGVPEADDVNVSRSDIERHVKGFNFSNESDIDLYEKLLKEGFDVISDALAEHDQIFVDT
KFEFGYVNDAAGNEKLIYMDEVGTPDSSRIWDGSSHRDGKIIEQSKEGFRQWLLNHFPDPDILLNKNRMVERFALASDNK
LPESVMMDISNTYVGIAEKIIGKKLHISDNPKQEIIDILRDEYQLIV

Specific function: Unknown

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=296, Percent_Identity=31.4189189189189, Blast_Score=110, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR014106
- InterPro:   IPR001636 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 41365; Mature: 41365

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLADKVLVVNDNLPIRTDKPVHSGKVRSVYWLTEEDSARLIKDKGYDVPADAPLAIMVI
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCCCEEEEEE
SDRISAFDCVWQGENGLNGVPGKGTALNAISNHWFKLFKDKGLADSHILDIPHPLVWIVQ
ECCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHH
KARPVMIEAIARQYITGSMWRSYTKGEREFCGITIPEGLEKDQKLPELLITPSTKGVLTG
HCCHHHHHHHHHHHHHHHHHHHHCCCCHHEECEECCCCCCHHHCCCCEEECCCCCHHHCC
LEGVPEADDVNVSRSDIERHVKGFNFSNESDIDLYEKLLKEGFDVISDALAEHDQIFVDT
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
KFEFGYVNDAAGNEKLIYMDEVGTPDSSRIWDGSSHRDGKIIEQSKEGFRQWLLNHFPDP
EEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
DILLNKNRMVERFALASDNKLPESVMMDISNTYVGIAEKIIGKKLHISDNPKQEIIDILR
CEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHH
DEYQLIV
HHHEECC
>Mature Secondary Structure
MNLADKVLVVNDNLPIRTDKPVHSGKVRSVYWLTEEDSARLIKDKGYDVPADAPLAIMVI
CCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCCCEEEEEE
SDRISAFDCVWQGENGLNGVPGKGTALNAISNHWFKLFKDKGLADSHILDIPHPLVWIVQ
ECCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEECCCCHHHHHHH
KARPVMIEAIARQYITGSMWRSYTKGEREFCGITIPEGLEKDQKLPELLITPSTKGVLTG
HCCHHHHHHHHHHHHHHHHHHHHCCCCHHEECEECCCCCCHHHCCCCEEECCCCCHHHCC
LEGVPEADDVNVSRSDIERHVKGFNFSNESDIDLYEKLLKEGFDVISDALAEHDQIFVDT
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEE
KFEFGYVNDAAGNEKLIYMDEVGTPDSSRIWDGSSHRDGKIIEQSKEGFRQWLLNHFPDP
EEEECCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
DILLNKNRMVERFALASDNKLPESVMMDISNTYVGIAEKIIGKKLHISDNPKQEIIDILR
CEEECCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHH
DEYQLIV
HHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA