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The map label for this gene is bioC [H]

Identifier: 157961627

GI number: 157961627

Start: 2202291

End: 2203061

Strand: Direct

Name: bioC [H]

Synonym: Spea_1803

Alternate gene names: 157961627

Gene position: 2202291-2203061 (Clockwise)

Preceding gene: 157961626

Following gene: 157961628

Centisome position: 42.56

GC content: 47.21

Gene sequence:

>771_bases
GTGAATACAGGATCAGAAAATCTTAGCCTAGAGGTCGCAGAGCGTTTCTCTGCAGCCGCTGCACATTATCACAGTTATGA
TGTGCTCCAGCAGCAGACGGCTAAGCGTTTGCTGGCGCAGATGACGCCAGGTACTCGCTTGCTTGATATCGGTGCAGGCC
CTGGTACGGACTTTTCCCAGTTTGAACATGTCAATCAAGTGTTCTGCCTCGATATTGCCGACGGCATGCTGAGAACACTG
AGCAGCAGCTTTCCCGAGCATGCGCCAATCTGTGGCGATGCCCAAAACCTACCGATTGCTGACGGTGTCATAGACAGTAT
TTACTCGAATGTCGCCTTACAATGGTGCCAAGATCTGCCACAAGCCGTGAGTGAAGCCAATAGAGTGCTCACTCAAGGTG
GTGAGTTCAATATGAGCATAGTCGCAAAAGATAGCCTGAAACAGTTAGTCGATTTGGGCTTTAAGGTGAATTCCTTTATC
GATGAGCAGGAGTTACTCGCTTGTTTTAACGATGATAATTGGCAGCTCGAGGTATGTAAAACCCTTGACGTTACGGTTTA
CTTTAGCGACTTAAGGGCATTGCTACAGTCGATAAAAGGTGTTGGTGCATCAATTGTTAAGCAACAACAGAGTGCTAATC
AGCCCCAAGTCACATTGAGAGGACGTAAAGATTGGCAAGCATTGCAGCTTAAGGCAGAGTTAAATCGAGCCCCAGAGGGC
CTACCTTTAACTTATAACATTAGCTTTATAAAGGCGCGTAAGAAGCGCTAA

Upstream 100 bases:

>100_bases
ATTGAACGATGATTAATGTGAGTGGGCATTCAGCCTTAACTCATTTTTAAAATTTAAACTAGAAACTATCAAAGTAATTG
ATTGTTTAGGATCCAATGCA

Downstream 100 bases:

>100_bases
ACGCAGCTGAGTCAACTTGGAGTAGACATGACATTTTTTGTAACGGGTACAGATACCGACTGTGGTAAGACGTTGATCTC
TTCTGCATTGTTAGCAGCAG

Product: type 11 methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNTGSENLSLEVAERFSAAAAHYHSYDVLQQQTAKRLLAQMTPGTRLLDIGAGPGTDFSQFEHVNQVFCLDIADGMLRTL
SSSFPEHAPICGDAQNLPIADGVIDSIYSNVALQWCQDLPQAVSEANRVLTQGGEFNMSIVAKDSLKQLVDLGFKVNSFI
DEQELLACFNDDNWQLEVCKTLDVTVYFSDLRALLQSIKGVGASIVKQQQSANQPQVTLRGRKDWQALQLKAELNRAPEG
LPLTYNISFIKARKKR

Sequences:

>Translated_256_residues
MNTGSENLSLEVAERFSAAAAHYHSYDVLQQQTAKRLLAQMTPGTRLLDIGAGPGTDFSQFEHVNQVFCLDIADGMLRTL
SSSFPEHAPICGDAQNLPIADGVIDSIYSNVALQWCQDLPQAVSEANRVLTQGGEFNMSIVAKDSLKQLVDLGFKVNSFI
DEQELLACFNDDNWQLEVCKTLDVTVYFSDLRALLQSIKGVGASIVKQQQSANQPQVTLRGRKDWQALQLKAELNRAPEG
LPLTYNISFIKARKKR
>Mature_256_residues
MNTGSENLSLEVAERFSAAAAHYHSYDVLQQQTAKRLLAQMTPGTRLLDIGAGPGTDFSQFEHVNQVFCLDIADGMLRTL
SSSFPEHAPICGDAQNLPIADGVIDSIYSNVALQWCQDLPQAVSEANRVLTQGGEFNMSIVAKDSLKQLVDLGFKVNSFI
DEQELLACFNDDNWQLEVCKTLDVTVYFSDLRALLQSIKGVGASIVKQQQSANQPQVTLRGRKDWQALQLKAELNRAPEG
LPLTYNISFIKARKKR

Specific function: BioC is involved in an early, but chemically unexplored, step in the conversion of pimelic acid to biotin [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1786994, Length=236, Percent_Identity=30.0847457627119, Blast_Score=88, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011814
- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 28305; Mature: 28305

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTGSENLSLEVAERFSAAAAHYHSYDVLQQQTAKRLLAQMTPGTRLLDIGAGPGTDFSQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHH
FEHVNQVFCLDIADGMLRTLSSSFPEHAPICGDAQNLPIADGVIDSIYSNVALQWCQDLP
HHHHHHEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAVSEANRVLTQGGEFNMSIVAKDSLKQLVDLGFKVNSFIDEQELLACFNDDNWQLEVCK
HHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCHHHHHCCHHHHHHHCCCCCCEEEEEE
TLDVTVYFSDLRALLQSIKGVGASIVKQQQSANQPQVTLRGRKDWQALQLKAELNRAPEG
EEEEEEEHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCC
LPLTYNISFIKARKKR
CEEEEEEHEECCCCCC
>Mature Secondary Structure
MNTGSENLSLEVAERFSAAAAHYHSYDVLQQQTAKRLLAQMTPGTRLLDIGAGPGTDFSQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHH
FEHVNQVFCLDIADGMLRTLSSSFPEHAPICGDAQNLPIADGVIDSIYSNVALQWCQDLP
HHHHHHEEEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QAVSEANRVLTQGGEFNMSIVAKDSLKQLVDLGFKVNSFIDEQELLACFNDDNWQLEVCK
HHHHHHHHHHHCCCCEEEEEEEHHHHHHHHHCCCHHHHHCCHHHHHHHCCCCCCEEEEEE
TLDVTVYFSDLRALLQSIKGVGASIVKQQQSANQPQVTLRGRKDWQALQLKAELNRAPEG
EEEEEEEHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCCCC
LPLTYNISFIKARKKR
CEEEEEEHEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8250549 [H]