Click here to switch to the map view.

The map label for this gene is thiL [H]

Identifier: 157960995

GI number: 157960995

Start: 1411838

End: 1412797

Strand: Direct

Name: thiL [H]

Synonym: Spea_1167

Alternate gene names: 157960995

Gene position: 1411838-1412797 (Clockwise)

Preceding gene: 157960994

Following gene: 157960996

Centisome position: 27.28

GC content: 47.29

Gene sequence:

>960_bases
GTGAAAGAATTTCAATTAATCGAAAGTTTCTTTACTGGGCGTGCCCAGTCCCGCAAAGATGTCGTTGTTGGTATTGGCGA
TGATTGCGCCATTGTTCAGCCAGCAGACAATAAATCTATTGCCATCTCTTGTGACACCTTAGTGGAAAATGTCCACTTCT
TCCCCGATATGCCAGCAGCCGATCTCGGTTATAAGTCCTTGGCGGTGAATCTATCAGATCTAGCCTCTATGGGCGCAGAG
CCTGCATGGATGACATTGGCACTGACACTACCTGAGGTCGATGAAACCTGGCTGGCTGAATTCAGTAGCGGCCTGTTTGA
TATTGCCGAGTATTACGGCGTGGCATTGATAGGGGGGGATACGACGCGTGGTCCTCGCTCAATTACCATCACCATCAACG
GCCAACTTCCAAATAATATCGGCTTGACCCGCAGCGGCGCTAAAAATGGTGATTGGATCTATGTGACGGGCACTTTAGGT
GATTCAGCACTGGGTTTAGATCTACTGAGAAATAAAGCCGAAGCGAATGCAGAGGACAGAGCCTATCTTATTCAACGTCA
TTATCGACCGACACCGAGAGTATTAGCTGGTCAGTCGCTTAGAAATATCGCCTCAAGTGCCATCGATATCTCAGATGGCA
TCATGTCAGATATTCAGCACGTGCTGAAAGCCTCTAATGTGGGCGCAGTAATAAACGTCGACAATATTCCATTGTCTGAG
CCACTTAAAGCCAGTGTTTCACCAGAGATGGCACTCAGTTATGCGCTGACAGGCGGTGAAGACTATGAGTTGTTGTTTAC
CGTCAATGAAGCGCAAAAAGGCATGCTAGAAGTCGCCTTAGCCGAGTCAGGAGTTAAGTTTACTCAGATAGGGCAGGTGT
GCACGGGTGGCCAGTTAAAGCTGCTTAGCGACAATAAACCGTTTGAACCGATAAACTTAGGTTTTGAGCACTTTAATTAA

Upstream 100 bases:

>100_bases
TTGAGCAAGCCTTATGGCTTCCTTTTTCGCTTGAGTGACGGCCTGAACTACACTTATCTCATTTCTCCCTGAATACTTAC
TCTTATTTGTGATTGGTATT

Downstream 100 bases:

>100_bases
TGAATCTACTCTCTAAAGACCCAGTGCTTGCAAAGCTATCACTGAAGAATCCTATACACTTCCTTGCGCTGGGTTTTGGC
TCAGGCTTAGCAGCCAAAGC

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MKEFQLIESFFTGRAQSRKDVVVGIGDDCAIVQPADNKSIAISCDTLVENVHFFPDMPAADLGYKSLAVNLSDLASMGAE
PAWMTLALTLPEVDETWLAEFSSGLFDIAEYYGVALIGGDTTRGPRSITITINGQLPNNIGLTRSGAKNGDWIYVTGTLG
DSALGLDLLRNKAEANAEDRAYLIQRHYRPTPRVLAGQSLRNIASSAIDISDGIMSDIQHVLKASNVGAVINVDNIPLSE
PLKASVSPEMALSYALTGGEDYELLFTVNEAQKGMLEVALAESGVKFTQIGQVCTGGQLKLLSDNKPFEPINLGFEHFN

Sequences:

>Translated_319_residues
MKEFQLIESFFTGRAQSRKDVVVGIGDDCAIVQPADNKSIAISCDTLVENVHFFPDMPAADLGYKSLAVNLSDLASMGAE
PAWMTLALTLPEVDETWLAEFSSGLFDIAEYYGVALIGGDTTRGPRSITITINGQLPNNIGLTRSGAKNGDWIYVTGTLG
DSALGLDLLRNKAEANAEDRAYLIQRHYRPTPRVLAGQSLRNIASSAIDISDGIMSDIQHVLKASNVGAVINVDNIPLSE
PLKASVSPEMALSYALTGGEDYELLFTVNEAQKGMLEVALAESGVKFTQIGQVCTGGQLKLLSDNKPFEPINLGFEHFN
>Mature_319_residues
MKEFQLIESFFTGRAQSRKDVVVGIGDDCAIVQPADNKSIAISCDTLVENVHFFPDMPAADLGYKSLAVNLSDLASMGAE
PAWMTLALTLPEVDETWLAEFSSGLFDIAEYYGVALIGGDTTRGPRSITITINGQLPNNIGLTRSGAKNGDWIYVTGTLG
DSALGLDLLRNKAEANAEDRAYLIQRHYRPTPRVLAGQSLRNIASSAIDISDGIMSDIQHVLKASNVGAVINVDNIPLSE
PLKASVSPEMALSYALTGGEDYELLFTVNEAQKGMLEVALAESGVKFTQIGQVCTGGQLKLLSDNKPFEPINLGFEHFN

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=318, Percent_Identity=55.9748427672956, Blast_Score=353, Evalue=9e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34302; Mature: 34302

Theoretical pI: Translated: 4.32; Mature: 4.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEFQLIESFFTGRAQSRKDVVVGIGDDCAIVQPADNKSIAISCDTLVENVHFFPDMPAA
CCHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCCEEEEEHHHHHHHHHCCCCCCCC
DLGYKSLAVNLSDLASMGAEPAWMTLALTLPEVDETWLAEFSSGLFDIAEYYGVALIGGD
CCCCHHEEEEHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHCEEEECCC
TTRGPRSITITINGQLPNNIGLTRSGAKNGDWIYVTGTLGDSALGLDLLRNKAEANAEDR
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHH
AYLIQRHYRPTPRVLAGQSLRNIASSAIDISDGIMSDIQHVLKASNVGAVINVDNIPLSE
HHHHHHCCCCCCCHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCC
PLKASVSPEMALSYALTGGEDYELLFTVNEAQKGMLEVALAESGVKFTQIGQVCTGGQLK
CCCCCCCCCCEEEEEECCCCCEEEEEEECCHHCCCEEEEEHHCCCEEEHHCCCCCCCEEE
LLSDNKPFEPINLGFEHFN
EECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKEFQLIESFFTGRAQSRKDVVVGIGDDCAIVQPADNKSIAISCDTLVENVHFFPDMPAA
CCHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCCCCEEEEEHHHHHHHHHCCCCCCCC
DLGYKSLAVNLSDLASMGAEPAWMTLALTLPEVDETWLAEFSSGLFDIAEYYGVALIGGD
CCCCHHEEEEHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHCEEEECCC
TTRGPRSITITINGQLPNNIGLTRSGAKNGDWIYVTGTLGDSALGLDLLRNKAEANAEDR
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCHH
AYLIQRHYRPTPRVLAGQSLRNIASSAIDISDGIMSDIQHVLKASNVGAVINVDNIPLSE
HHHHHHCCCCCCCHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCC
PLKASVSPEMALSYALTGGEDYELLFTVNEAQKGMLEVALAESGVKFTQIGQVCTGGQLK
CCCCCCCCCCEEEEEECCCCCEEEEEEECCHHCCCEEEEEHHCCCEEEHHCCCCCCCEEE
LLSDNKPFEPINLGFEHFN
EECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]