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The map label for this gene is ytfL [H]

Identifier: 157960735

GI number: 157960735

Start: 1107696

End: 1109018

Strand: Direct

Name: ytfL [H]

Synonym: Spea_0907

Alternate gene names: 157960735

Gene position: 1107696-1109018 (Clockwise)

Preceding gene: 157960732

Following gene: 157960739

Centisome position: 21.41

GC content: 45.8

Gene sequence:

>1323_bases
ATGAGCTTCTTTGATAATGCTGTGATTATATTACTCCTGATTGGAGTGAGTTGTTTCTTTTCAATGTCAGAAATTGCCCT
TGCGGCTGGGCGTAAAATTCGCTTGCGTCAGCTAGCGGCTGAAGGCGATGTTCGAGCCGACAAAGTGCTGCTACTGCAAG
CGCAGCCAGGTAACTTTTTTACTGTGGTACAGATAGGTTTAAATGCCGTGGCTATCATGGGCGGTATCGTCGGTGAGTCA
GCTTTTACTCCTCATATTCACGCATTTTTGTCGTCTTGGTTGACCGGACCCTGGCTAGACAAAATGAGCTTCCTGTTGTC
ATTTGTGATTGTGACCAGCTTATTCATCTTGATTGCCGACCTAATTCCAAAGCGTTTAGCGATGGCCTTTCCTGAAAAGG
TGGCGATGACCTTTGTTGGTCCTATGATGGTCTGCATCGTGCTGCTCAAGCCTCTAGTGTGGTTCTTTAACGGTGCTGCG
AATCTTGTTTTTCGTGTGTTTCAAGTTCAGACCGCACGTAATGATGCAGTGACCTCGGATGACATCTATGCCGTGATGGA
TGCGGGCGCCGAAGCTGGTGTGCTTGATAAAGGCGATCAGTTGATGATGGAAAAAGTGTTTGAGATGCAAACAATTCCTG
TCACCGCAGCGATGACGGCGCGTGAAAGCCTGGTCTACTTTTTACTGCAAGACAGTGAAGAAGAGATAATGAGCAAGATT
TCCCAGCAGCCCCATTCTAACTTCTTAGTTTGTGATGAGCAGTTAGATACAGTCGTTGGCTTCGTCAATGCCAAGAAGTT
ACTTATTTGTCTGATTAATGGCGAGAAAATTAGCCTTAAAGACAAGAGCCTAGTTAGCACTTGCTTTATTGTGCCAGACA
CTTTGAGCCTATCTGAGTCGATGGATTATTTCAAAAATAGCCGTGCCGATTTTGCTGTGGTGATGAATGAGTATTCTTTG
GTGGTGGGTATTGTGACGGCTAAAGATTTGCAAGATGCGGTGATGGGAGCCTGGTCTTTGCCTGAGTGTGAAGAGCAGAT
TATAGCCCGCGATGAACGCTCTTGGTTGATGGATGGCGTAACGCCGATCACAGATGTGATGCGCGCGCTCGATATCGAGG
AGTTTCCACAGAATCATAACTACGAAACTATCGCAGGTTTTATGATGTTTATGCTGCGTAAGATCCCGAAGTGCACCGAT
TCTGTCAATCATGCCGGCTTTAAGTTTGAAGTGGTGGATGTAGATAGCTACAAAGTGGATCAGCTGTTGGTTACCCGTAT
CGATGATTCCAGCAAGGTTGAAGATTTAGAGCTTAAGCTATAA

Upstream 100 bases:

>100_bases
TTATACAGGGTTCTGCTTGGGGGAAATGAGTACCAATAAGTAGAAATAATGATATGCAGTAAAGGGATAAGTGTGTTTTT
AGTTTTGAGAAAGGTGCTAA

Downstream 100 bases:

>100_bases
CGACAAGCTGTGTTTTGCGAAGGTGGGTCAAGCTTGACTCACCTTTATGTTTTTCACTTGTTACTAGCAATCACTCCCAA
TCACTCCCTTGTGGCTCAGT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 439

Protein sequence:

>440_residues
MSFFDNAVIILLLIGVSCFFSMSEIALAAGRKIRLRQLAAEGDVRADKVLLLQAQPGNFFTVVQIGLNAVAIMGGIVGES
AFTPHIHAFLSSWLTGPWLDKMSFLLSFVIVTSLFILIADLIPKRLAMAFPEKVAMTFVGPMMVCIVLLKPLVWFFNGAA
NLVFRVFQVQTARNDAVTSDDIYAVMDAGAEAGVLDKGDQLMMEKVFEMQTIPVTAAMTARESLVYFLLQDSEEEIMSKI
SQQPHSNFLVCDEQLDTVVGFVNAKKLLICLINGEKISLKDKSLVSTCFIVPDTLSLSESMDYFKNSRADFAVVMNEYSL
VVGIVTAKDLQDAVMGAWSLPECEEQIIARDERSWLMDGVTPITDVMRALDIEEFPQNHNYETIAGFMMFMLRKIPKCTD
SVNHAGFKFEVVDVDSYKVDQLLVTRIDDSSKVEDLELKL

Sequences:

>Translated_440_residues
MSFFDNAVIILLLIGVSCFFSMSEIALAAGRKIRLRQLAAEGDVRADKVLLLQAQPGNFFTVVQIGLNAVAIMGGIVGES
AFTPHIHAFLSSWLTGPWLDKMSFLLSFVIVTSLFILIADLIPKRLAMAFPEKVAMTFVGPMMVCIVLLKPLVWFFNGAA
NLVFRVFQVQTARNDAVTSDDIYAVMDAGAEAGVLDKGDQLMMEKVFEMQTIPVTAAMTARESLVYFLLQDSEEEIMSKI
SQQPHSNFLVCDEQLDTVVGFVNAKKLLICLINGEKISLKDKSLVSTCFIVPDTLSLSESMDYFKNSRADFAVVMNEYSL
VVGIVTAKDLQDAVMGAWSLPECEEQIIARDERSWLMDGVTPITDVMRALDIEEFPQNHNYETIAGFMMFMLRKIPKCTD
SVNHAGFKFEVVDVDSYKVDQLLVTRIDDSSKVEDLELKL
>Mature_439_residues
SFFDNAVIILLLIGVSCFFSMSEIALAAGRKIRLRQLAAEGDVRADKVLLLQAQPGNFFTVVQIGLNAVAIMGGIVGESA
FTPHIHAFLSSWLTGPWLDKMSFLLSFVIVTSLFILIADLIPKRLAMAFPEKVAMTFVGPMMVCIVLLKPLVWFFNGAAN
LVFRVFQVQTARNDAVTSDDIYAVMDAGAEAGVLDKGDQLMMEKVFEMQTIPVTAAMTARESLVYFLLQDSEEEIMSKIS
QQPHSNFLVCDEQLDTVVGFVNAKKLLICLINGEKISLKDKSLVSTCFIVPDTLSLSESMDYFKNSRADFAVVMNEYSLV
VGIVTAKDLQDAVMGAWSLPECEEQIIARDERSWLMDGVTPITDVMRALDIEEFPQNHNYETIAGFMMFMLRKIPKCTDS
VNHAGFKFEVVDVDSYKVDQLLVTRIDDSSKVEDLELKL

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=389, Percent_Identity=23.1362467866324, Blast_Score=133, Evalue=4e-31,
Organism=Escherichia coli, GI1790664, Length=437, Percent_Identity=54.233409610984, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI145693175, Length=419, Percent_Identity=21.7183770883055, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI87082033, Length=266, Percent_Identity=27.4436090225564, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788119, Length=262, Percent_Identity=25.1908396946565, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786879, Length=274, Percent_Identity=22.992700729927, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48949; Mature: 48818

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFDNAVIILLLIGVSCFFSMSEIALAAGRKIRLRQLAAEGDVRADKVLLLQAQPGNFF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEECCCCEE
TVVQIGLNAVAIMGGIVGESAFTPHIHAFLSSWLTGPWLDKMSFLLSFVIVTSLFILIAD
EEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LIPKRLAMAFPEKVAMTFVGPMMVCIVLLKPLVWFFNGAANLVFRVFQVQTARNDAVTSD
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCC
DIYAVMDAGAEAGVLDKGDQLMMEKVFEMQTIPVTAAMTARESLVYFLLQDSEEEIMSKI
CHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCHHHHHHHH
SQQPHSNFLVCDEQLDTVVGFVNAKKLLICLINGEKISLKDKSLVSTCFIVPDTLSLSES
HCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEECCCEEECCCHHHHHEEEECCCCCCHHHH
MDYFKNSRADFAVVMNEYSLVVGIVTAKDLQDAVMGAWSLPECEEQIIARDERSWLMDGV
HHHHHCCCCCEEEEEECCEEEEEEEEHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHCCC
TPITDVMRALDIEEFPQNHNYETIAGFMMFMLRKIPKCTDSVNHAGFKFEVVDVDSYKVD
CHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEEEECCCCCHH
QLLVTRIDDSSKVEDLELKL
HHHEEECCCCCCCCCCEECC
>Mature Secondary Structure 
SFFDNAVIILLLIGVSCFFSMSEIALAAGRKIRLRQLAAEGDVRADKVLLLQAQPGNFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEEEECCCCEE
TVVQIGLNAVAIMGGIVGESAFTPHIHAFLSSWLTGPWLDKMSFLLSFVIVTSLFILIAD
EEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
LIPKRLAMAFPEKVAMTFVGPMMVCIVLLKPLVWFFNGAANLVFRVFQVQTARNDAVTSD
HHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCC
DIYAVMDAGAEAGVLDKGDQLMMEKVFEMQTIPVTAAMTARESLVYFLLQDSEEEIMSKI
CHHEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHEEEEECCCHHHHHHHH
SQQPHSNFLVCDEQLDTVVGFVNAKKLLICLINGEKISLKDKSLVSTCFIVPDTLSLSES
HCCCCCCEEEEHHHHHHHHHHHCCCEEEEEEECCCEEECCCHHHHHEEEECCCCCCHHHH
MDYFKNSRADFAVVMNEYSLVVGIVTAKDLQDAVMGAWSLPECEEQIIARDERSWLMDGV
HHHHHCCCCCEEEEEECCEEEEEEEEHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHCCC
TPITDVMRALDIEEFPQNHNYETIAGFMMFMLRKIPKCTDSVNHAGFKFEVVDVDSYKVD
CHHHHHHHHHCHHHCCCCCCHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEEEECCCCCHH
QLLVTRIDDSSKVEDLELKL
HHHEEECCCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]