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The map label for this gene is hdfR [H]

Identifier: 157372996

GI number: 157372996

Start: 5270889

End: 5271722

Strand: Direct

Name: hdfR [H]

Synonym: Spro_4764

Alternate gene names: 157372996

Gene position: 5270889-5271722 (Clockwise)

Preceding gene: 157372994

Following gene: 157373003

Centisome position: 96.73

GC content: 54.32

Gene sequence:

>834_bases
ATGGGTGTGGATACCGAATTACTGAAAACCTTTTTGGAGGTCAGTAGAACGCGTCACTTTGGCCGAGCCGCAGAATCCTT
GTACTTAACGCAGTCCGCCGTTAGTTTTCGTATCCGCCAGTTAGAAACCCAATTGGGCGCGAATTTATTCACCCGACATC
GTAACAATATCCGTCTGACGCCAGCAGGGGAGCGGCTTCTGCCCTATGCTGAGAGCCTGATGACCACCTGGCAATTGGCG
AAAAAAGAGGTGGTGCGTTCGCTGCAGCATACTGAATTGTCCATCGGTGCCACCGCGTCATTGTGGGAAGCTTATCTGAC
CCCGTGGCTGCAATCGTTGTATCAACAACGCGAGGCATTACAGCTGGAAGCCAGGGTGGCGTTACGGCACTCTTTGGTAA
AACAGCTGCATGAAAGACAGCTCGATTTGCTCATCACCACCGAGCCGCCAAAAATGGATGAACTGGCCAGCCAGCTGTTG
GGCAATTTCTCGCTGCGGCTGTTCTCCTCCACCCTGCGTGATAAACATGCGCCGATGCCGTATATCAAGCTGGAATGGGG
GGCGGATTTTCATCAGCAGGAGAGCCGTATGCTGGAGGGGGATAATTTGCCGGTACTCACCACAACCTCCGCACACCTGA
CCCGACAACTACTGGAAACCACCGGCGGCTGCGCCTTCCTGCCCAGTCAATGGGAGAAGGACTACCCGCAGTTGGCCGCC
ATTGCCGACATCCCGCCGATAATCCGCCCGCTGTATGCCGTTTGGCTGCAAAATAGCGATCAGCAGCCGCTGATCCGGCA
ACTGCTGAAAATACCTTTAAATACTACGGCATGA

Upstream 100 bases:

>100_bases
AATTCTCTCATGGCCGTGCTGTTTATGGCGCGGAGTATTAGATAGGCTTGACATTGTGTAAAACAAAACATTTAAATCTT
AACGATAAAAATTTCTGGAG

Downstream 100 bases:

>100_bases
GGCGTTATAACGGCGTTAAGCGAGGATGCCGGGGTTTGGTTCGTCTACCGAGCCAAAACGCGCTCATCGCCTTCTGAAGG
CCGATAAAGCCGAACAACAG

Product: transcriptional regulator HdfR

Products: NA

Alternate protein names: H-NS-dependent flhDC regulator [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MGVDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLETQLGANLFTRHRNNIRLTPAGERLLPYAESLMTTWQLA
KKEVVRSLQHTELSIGATASLWEAYLTPWLQSLYQQREALQLEARVALRHSLVKQLHERQLDLLITTEPPKMDELASQLL
GNFSLRLFSSTLRDKHAPMPYIKLEWGADFHQQESRMLEGDNLPVLTTTSAHLTRQLLETTGGCAFLPSQWEKDYPQLAA
IADIPPIIRPLYAVWLQNSDQQPLIRQLLKIPLNTTA

Sequences:

>Translated_277_residues
MGVDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLETQLGANLFTRHRNNIRLTPAGERLLPYAESLMTTWQLA
KKEVVRSLQHTELSIGATASLWEAYLTPWLQSLYQQREALQLEARVALRHSLVKQLHERQLDLLITTEPPKMDELASQLL
GNFSLRLFSSTLRDKHAPMPYIKLEWGADFHQQESRMLEGDNLPVLTTTSAHLTRQLLETTGGCAFLPSQWEKDYPQLAA
IADIPPIIRPLYAVWLQNSDQQPLIRQLLKIPLNTTA
>Mature_276_residues
GVDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLETQLGANLFTRHRNNIRLTPAGERLLPYAESLMTTWQLAK
KEVVRSLQHTELSIGATASLWEAYLTPWLQSLYQQREALQLEARVALRHSLVKQLHERQLDLLITTEPPKMDELASQLLG
NFSLRLFSSTLRDKHAPMPYIKLEWGADFHQQESRMLEGDNLPVLTTTSAHLTRQLLETTGGCAFLPSQWEKDYPQLAAI
ADIPPIIRPLYAVWLQNSDQQPLIRQLLKIPLNTTA

Specific function: Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI48994962, Length=274, Percent_Identity=63.1386861313869, Blast_Score=350, Evalue=5e-98,
Organism=Escherichia coli, GI2367136, Length=174, Percent_Identity=29.8850574712644, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1788626, Length=150, Percent_Identity=32, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI157672245, Length=290, Percent_Identity=24.8275862068966, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87081904, Length=261, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=174, Percent_Identity=27.0114942528736, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020890
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31691; Mature: 31560

Theoretical pI: Translated: 8.45; Mature: 8.45

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLETQLGANLFTRHRNNIRLT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
PAGERLLPYAESLMTTWQLAKKEVVRSLQHTELSIGATASLWEAYLTPWLQSLYQQREAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QLEARVALRHSLVKQLHERQLDLLITTEPPKMDELASQLLGNFSLRLFSSTLRDKHAPMP
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YIKLEWGADFHQQESRMLEGDNLPVLTTTSAHLTRQLLETTGGCAFLPSQWEKDYPQLAA
EEEEECCCCHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHCCCCEECCCHHCCCCHHHHH
IADIPPIIRPLYAVWLQNSDQQPLIRQLLKIPLNTTA
HHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GVDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLETQLGANLFTRHRNNIRLT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEC
PAGERLLPYAESLMTTWQLAKKEVVRSLQHTELSIGATASLWEAYLTPWLQSLYQQREAL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
QLEARVALRHSLVKQLHERQLDLLITTEPPKMDELASQLLGNFSLRLFSSTLRDKHAPMP
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
YIKLEWGADFHQQESRMLEGDNLPVLTTTSAHLTRQLLETTGGCAFLPSQWEKDYPQLAA
EEEEECCCCHHHHHHHHCCCCCCCEEECCHHHHHHHHHHHCCCCEECCCHHCCCCHHHHH
IADIPPIIRPLYAVWLQNSDQQPLIRQLLKIPLNTTA
HHCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA