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The map label for this gene is comM [H]

Identifier: 157372994

GI number: 157372994

Start: 5268886

End: 5270409

Strand: Direct

Name: comM [H]

Synonym: Spro_4762

Alternate gene names: 157372994

Gene position: 5268886-5270409 (Clockwise)

Preceding gene: 157372984

Following gene: 157372996

Centisome position: 96.7

GC content: 60.24

Gene sequence:

>1524_bases
ATGTCACTGGCGGTTATCTATACCCGAGCCACGCTGGGCGTTCAGGCCCCTTCGGTTACGGTGGAAGTGCATATCAGCAA
CGGGCTACCCGGTCTGACCATGGTCGGCCTGCCGGAAACTACGGTGAAAGAAGCCCGCGATCGGGTACGCAGTGCGTTGA
TCAACAATGGCTTCACCTTTCCCGCGCGGCGTATCACCGTCAATCTGGCACCGGCCGATTTACCCAAGGAAGGTGGGCGT
TATGACCTGCCGATCGCTTTGGCGATCCTCGCCGCCTCCGAACAGTTACCGGCCGATAAGCTGGCTCGTTATGAGTTCCT
TGGGGAGTTGGCGCTATCCGGCGCACTACGGGGAGTCAGTGGCGCGATACCCGCCGCGCTGGCCGCAATGGATGCGGGCA
GGCAGTTGATTCTGGCTGCCACCAATGGCCGAGAGGTGGGGTTGATTACCCAGAGCGAGACCCTGGTGGCAGAACACCTG
CTGGAGGTGTGCGCCTTTCTGCTGGGTAAAGGGGACTTACCGATAGCCAGCGCGCCGCCGGCAATGGAGAGCGCGCAAGA
ACCGGCCGACCTGCAAGATATCCTGGGCCAGGAACAGGCTAAACGGGCGTTGGAGATCGCCGCAGCCGGGGGTCACAACC
TGCTGCTGGTCGGCCCACCGGGAACCGGGAAAACCATGCTGGCCAGCCGTTTGAATGGCCTGCTGCCCCCGCTGACCGAA
CGAGAGGCACTGGAAAGCATCGCGGTAGCCAGTCTGCTGCATCACCCTGCACAAGCGCTGCCATGGCGACAGCGGCCGTT
TCGCGCACCGCATCACAGTGCCTCGATGGCCGCGCTGGTCGGCGGTGGCTCACTGCCGCGGCCGGGTGAGATATCCATGG
CGCACAACGGCGTGCTGTTTCTTGATGAGTTGCCCGAATTTGAAAGACGAGTGCTGGATGCCCTGCGTGAACCCCTGGAG
TCCGGCGAAATAGTCATTTCTCGCGCTACGGCCAAGGTCTGCTTTCCGGCCAGAGTGCAGCTAATTGCCGCCATGAACCC
CAGCCCCACCGGGCATTATCAGGGCATGCATAACCGCGCGTCCCCACAACAGATCCTGCGCTATCTCGGGCGGCTTTCAG
GGCCGTTTCTCGATCGCTTCGATTTATCGATTGAAGTGCCACTGCTGCCACCGGGCGTGCTGAGCAAACGACGCATCGCC
GGTGAAAGTAGTACTCAGGTACGAAAGCGGGTGCTGCTGGCACGCGAAAGGCAGCTCAACCGTTCAGGGAAGATCAACGC
CCTGCTGAATAATCACGAGGTAGAGCGTGATTGCGCATTGAGCGAAGCGGACGCAGATTTTCTTGAGACGACGTTAAATC
GATTGGGATTATCGGTTCGCGCCTGGCAGCGGATTTTAAAAGTGGCTCGCACCCTGGCGGATTTAGCAGGAGATCGGGAT
ATTGATAAGCGCCATTTGAGCGAAGCGCTGGGTTATCGCAGTATGGATCGCCTGTTGCTGCAGCTGCACCGCAGCCTGGA
GTAA

Upstream 100 bases:

>100_bases
TTCATTGTTTTAATTGCGGCTTTCCACGCAAACATTCCAAGGTTACCGCGCCTTGCCAGGGCCTTTGCCGCATCATGTTG
CCTACAGCAAGGAGAGCAAT

Downstream 100 bases:

>100_bases
AAATGGGGCCCAAAGGCCCCATCGTTATCAATCGTCGCTGTCGGTGTAATCTTCCACCGCATCAGCCTGCGGCTTGCCAC
CGGACAGGGTATGGAATTTT

Product: Mg chelatase subunit ChlI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MSLAVIYTRATLGVQAPSVTVEVHISNGLPGLTMVGLPETTVKEARDRVRSALINNGFTFPARRITVNLAPADLPKEGGR
YDLPIALAILAASEQLPADKLARYEFLGELALSGALRGVSGAIPAALAAMDAGRQLILAATNGREVGLITQSETLVAEHL
LEVCAFLLGKGDLPIASAPPAMESAQEPADLQDILGQEQAKRALEIAAAGGHNLLLVGPPGTGKTMLASRLNGLLPPLTE
REALESIAVASLLHHPAQALPWRQRPFRAPHHSASMAALVGGGSLPRPGEISMAHNGVLFLDELPEFERRVLDALREPLE
SGEIVISRATAKVCFPARVQLIAAMNPSPTGHYQGMHNRASPQQILRYLGRLSGPFLDRFDLSIEVPLLPPGVLSKRRIA
GESSTQVRKRVLLARERQLNRSGKINALLNNHEVERDCALSEADADFLETTLNRLGLSVRAWQRILKVARTLADLAGDRD
IDKRHLSEALGYRSMDRLLLQLHRSLE

Sequences:

>Translated_507_residues
MSLAVIYTRATLGVQAPSVTVEVHISNGLPGLTMVGLPETTVKEARDRVRSALINNGFTFPARRITVNLAPADLPKEGGR
YDLPIALAILAASEQLPADKLARYEFLGELALSGALRGVSGAIPAALAAMDAGRQLILAATNGREVGLITQSETLVAEHL
LEVCAFLLGKGDLPIASAPPAMESAQEPADLQDILGQEQAKRALEIAAAGGHNLLLVGPPGTGKTMLASRLNGLLPPLTE
REALESIAVASLLHHPAQALPWRQRPFRAPHHSASMAALVGGGSLPRPGEISMAHNGVLFLDELPEFERRVLDALREPLE
SGEIVISRATAKVCFPARVQLIAAMNPSPTGHYQGMHNRASPQQILRYLGRLSGPFLDRFDLSIEVPLLPPGVLSKRRIA
GESSTQVRKRVLLARERQLNRSGKINALLNNHEVERDCALSEADADFLETTLNRLGLSVRAWQRILKVARTLADLAGDRD
IDKRHLSEALGYRSMDRLLLQLHRSLE
>Mature_506_residues
SLAVIYTRATLGVQAPSVTVEVHISNGLPGLTMVGLPETTVKEARDRVRSALINNGFTFPARRITVNLAPADLPKEGGRY
DLPIALAILAASEQLPADKLARYEFLGELALSGALRGVSGAIPAALAAMDAGRQLILAATNGREVGLITQSETLVAEHLL
EVCAFLLGKGDLPIASAPPAMESAQEPADLQDILGQEQAKRALEIAAAGGHNLLLVGPPGTGKTMLASRLNGLLPPLTER
EALESIAVASLLHHPAQALPWRQRPFRAPHHSASMAALVGGGSLPRPGEISMAHNGVLFLDELPEFERRVLDALREPLES
GEIVISRATAKVCFPARVQLIAAMNPSPTGHYQGMHNRASPQQILRYLGRLSGPFLDRFDLSIEVPLLPPGVLSKRRIAG
ESSTQVRKRVLLARERQLNRSGKINALLNNHEVERDCALSEADADFLETTLNRLGLSVRAWQRILKVARTLADLAGDRDI
DKRHLSEALGYRSMDRLLLQLHRSLE

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=506, Percent_Identity=65.4150197628458, Blast_Score=674, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 54690; Mature: 54559

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50051 MCM_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLAVIYTRATLGVQAPSVTVEVHISNGLPGLTMVGLPETTVKEARDRVRSALINNGFTF
CCEEEEEEEEECCCCCCCEEEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCC
PARRITVNLAPADLPKEGGRYDLPIALAILAASEQLPADKLARYEFLGELALSGALRGVS
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GAIPAALAAMDAGRQLILAATNGREVGLITQSETLVAEHLLEVCAFLLGKGDLPIASAPP
CHHHHHHHHHHCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
AMESAQEPADLQDILGQEQAKRALEIAAAGGHNLLLVGPPGTGKTMLASRLNGLLPPLTE
HHHHCCCCCHHHHHHCHHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHCCCCCCCH
REALESIAVASLLHHPAQALPWRQRPFRAPHHSASMAALVGGGSLPRPGEISMAHNGVLF
HHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCHHHEECCCCCCCCCCEEEECCCEEE
LDELPEFERRVLDALREPLESGEIVISRATAKVCFPARVQLIAAMNPSPTGHYQGMHNRA
ECCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHEEEEEECCCCCCCCCCCCCCCC
SPQQILRYLGRLSGPFLDRFDLSIEVPLLPPGVLSKRRIAGESSTQVRKRVLLARERQLN
CHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCC
RSGKINALLNNHEVERDCALSEADADFLETTLNRLGLSVRAWQRILKVARTLADLAGDRD
CCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
IDKRHLSEALGYRSMDRLLLQLHRSLE
HHHHHHHHHHCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLAVIYTRATLGVQAPSVTVEVHISNGLPGLTMVGLPETTVKEARDRVRSALINNGFTF
CEEEEEEEEECCCCCCCEEEEEEECCCCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCC
PARRITVNLAPADLPKEGGRYDLPIALAILAASEQLPADKLARYEFLGELALSGALRGVS
CCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCC
GAIPAALAAMDAGRQLILAATNGREVGLITQSETLVAEHLLEVCAFLLGKGDLPIASAPP
CHHHHHHHHHHCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCC
AMESAQEPADLQDILGQEQAKRALEIAAAGGHNLLLVGPPGTGKTMLASRLNGLLPPLTE
HHHHCCCCCHHHHHHCHHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHCCCCCCCH
REALESIAVASLLHHPAQALPWRQRPFRAPHHSASMAALVGGGSLPRPGEISMAHNGVLF
HHHHHHHHHHHHHHCHHHHCCCCCCCCCCCCCCCCHHHEECCCCCCCCCCEEEECCCEEE
LDELPEFERRVLDALREPLESGEIVISRATAKVCFPARVQLIAAMNPSPTGHYQGMHNRA
ECCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHCCHHHEEEEEECCCCCCCCCCCCCCCC
SPQQILRYLGRLSGPFLDRFDLSIEVPLLPPGVLSKRRIAGESSTQVRKRVLLARERQLN
CHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCC
RSGKINALLNNHEVERDCALSEADADFLETTLNRLGLSVRAWQRILKVARTLADLAGDRD
CCCCEEEEECCCCCHHHHCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
IDKRHLSEALGYRSMDRLLLQLHRSLE
HHHHHHHHHHCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]