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The map label for this gene is nahR [H]

Identifier: 157372943

GI number: 157372943

Start: 5206205

End: 5207083

Strand: Direct

Name: nahR [H]

Synonym: Spro_4711

Alternate gene names: 157372943

Gene position: 5206205-5207083 (Clockwise)

Preceding gene: 157372930

Following gene: 157372945

Centisome position: 95.55

GC content: 62.8

Gene sequence:

>879_bases
TTGGTCACGCTGGAAGCGCTGCTCACTGAGCGCAGCGTAACCCGGGCGGCCGCACGCCTTAACCTGAGCCAACCCTCGGT
CAGTATCCAGCTCGCCAAACTGCGCGAGATTTACCATGATCCCCTGCTATTACCCGGCTCACGCGGCATGTTGCCCACGG
CACGCGCACTCGGCCTGCTGACGCCGCTGCGCCAGACGCTGGCCGATCTCGGCCGCCTGGTGGCACCGGAACAGCCGTTT
GATCCGCTACAGGCCAAAATGACCTGGCAACTGGCCGCCGCCGATGCGGCCGAATATGCCATCCTGCTGCCGATGCTGCC
CAAACTGCGGCTGGCGGCACCCCATTCCCGTCTGGCGATCCGCGAAGCGTCCCCCAAAAATATGAGCCGCGATCTGGCGG
ACGGCGTGATCGACCTGGGTTTTCTGGCCCGTGAAGAGGCGCCCGCCGAGCTACGTCATCGCCCGTTGTTCCACGAGAAT
TACCTGCTGGTAGGCCGTCGTGACCACCCGTTATTGCAGACCCCGCCTACGCTCGAGCAGTTCTGTCAGTTGGAGTTTGT
TATGGTTTCACAGGACGGGGGCGGTTTTCGTACCCTGACCGACACGTTGCTGGAAGCACAGGGATTAGCGCGGCGCGTTG
TGATGTCGCTGCCACACTTCCTGTTCATTCCCGCGCTGCTGGCAAAATCCGATATGGTGGCGATGCTGCCTTCACGCATG
CTGGGGGAACTGCTCGGCAGTCTGCGCACCTGCCCGGTGCCGCTGGAACTACCCGGCTATGACATGGTGATGGTCTGGCA
TGAGCGATCGCACCTGGATCCGGCCCATAGCTGGCTGCGCGAGCAGGTGGTTGCCGCCCTGGAGTCATCAACTGCGTAA

Upstream 100 bases:

>100_bases
CGTCCGTTCCACGGTAGTGGGATTAACGCTATAGTTGAAATTGATAGATTTAATATGAGGAATAGTTATCAACAATTTAA
AGCGGGTCGATCTCAATTTA

Downstream 100 bases:

>100_bases
CTAGAAGACATCGACCAGGTCAAACTCTTCAAATACCAGCCACATTTGCGGCGAAAAAATACCTTCTCGGGTAAAAAACG
CCTGATGTCCCTCACGCCAA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MVTLEALLTERSVTRAAARLNLSQPSVSIQLAKLREIYHDPLLLPGSRGMLPTARALGLLTPLRQTLADLGRLVAPEQPF
DPLQAKMTWQLAAADAAEYAILLPMLPKLRLAAPHSRLAIREASPKNMSRDLADGVIDLGFLAREEAPAELRHRPLFHEN
YLLVGRRDHPLLQTPPTLEQFCQLEFVMVSQDGGGFRTLTDTLLEAQGLARRVVMSLPHFLFIPALLAKSDMVAMLPSRM
LGELLGSLRTCPVPLELPGYDMVMVWHERSHLDPAHSWLREQVVAALESSTA

Sequences:

>Translated_292_residues
MVTLEALLTERSVTRAAARLNLSQPSVSIQLAKLREIYHDPLLLPGSRGMLPTARALGLLTPLRQTLADLGRLVAPEQPF
DPLQAKMTWQLAAADAAEYAILLPMLPKLRLAAPHSRLAIREASPKNMSRDLADGVIDLGFLAREEAPAELRHRPLFHEN
YLLVGRRDHPLLQTPPTLEQFCQLEFVMVSQDGGGFRTLTDTLLEAQGLARRVVMSLPHFLFIPALLAKSDMVAMLPSRM
LGELLGSLRTCPVPLELPGYDMVMVWHERSHLDPAHSWLREQVVAALESSTA
>Mature_292_residues
MVTLEALLTERSVTRAAARLNLSQPSVSIQLAKLREIYHDPLLLPGSRGMLPTARALGLLTPLRQTLADLGRLVAPEQPF
DPLQAKMTWQLAAADAAEYAILLPMLPKLRLAAPHSRLAIREASPKNMSRDLADGVIDLGFLAREEAPAELRHRPLFHEN
YLLVGRRDHPLLQTPPTLEQFCQLEFVMVSQDGGGFRTLTDTLLEAQGLARRVVMSLPHFLFIPALLAKSDMVAMLPSRM
LGELLGSLRTCPVPLELPGYDMVMVWHERSHLDPAHSWLREQVVAALESSTA

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=297, Percent_Identity=25.2525252525253, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1790147, Length=299, Percent_Identity=25.4180602006689, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081766, Length=253, Percent_Identity=26.8774703557312, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787879, Length=289, Percent_Identity=26.9896193771626, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32371; Mature: 32371

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLEALLTERSVTRAAARLNLSQPSVSIQLAKLREIYHDPLLLPGSRGMLPTARALGLL
CEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHH
TPLRQTLADLGRLVAPEQPFDPLQAKMTWQLAAADAAEYAILLPMLPKLRLAAPHSRLAI
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCHHHHCCCCHHEEE
REASPKNMSRDLADGVIDLGFLAREEAPAELRHRPLFHENYLLVGRRDHPLLQTPPTLEQ
ECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHH
FCQLEFVMVSQDGGGFRTLTDTLLEAQGLARRVVMSLPHFLFIPALLAKSDMVAMLPSRM
HHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHH
LGELLGSLRTCPVPLELPGYDMVMVWHERSHLDPAHSWLREQVVAALESSTA
HHHHHHHHCCCCCCEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVTLEALLTERSVTRAAARLNLSQPSVSIQLAKLREIYHDPLLLPGSRGMLPTARALGLL
CEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHH
TPLRQTLADLGRLVAPEQPFDPLQAKMTWQLAAADAAEYAILLPMLPKLRLAAPHSRLAI
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCHHHHHHHHHCCCHHHHCCCCHHEEE
REASPKNMSRDLADGVIDLGFLAREEAPAELRHRPLFHENYLLVGRRDHPLLQTPPTLEQ
ECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEECCCCCCCCCCHHHHH
FCQLEFVMVSQDGGGFRTLTDTLLEAQGLARRVVMSLPHFLFIPALLAKSDMVAMLPSRM
HHCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCHHHHHHHHHH
LGELLGSLRTCPVPLELPGYDMVMVWHERSHLDPAHSWLREQVVAALESSTA
HHHHHHHHCCCCCCEECCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]