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The map label for this gene is hslO

Identifier: 157372848

GI number: 157372848

Start: 5091844

End: 5092722

Strand: Direct

Name: hslO

Synonym: Spro_4616

Alternate gene names: 157372848

Gene position: 5091844-5092722 (Clockwise)

Preceding gene: 157372847

Following gene: 157372849

Centisome position: 93.45

GC content: 57.11

Gene sequence:

>879_bases
ATGTCTAACCATGACCAATTGCACCGTTACCTGTTTGAAAACTACGCGGTGCGCGGTGAGCTGGTTACCGTCAGCGAAAC
CTATCAGCAGGTTCTGAACAACCACGACTATCCGGCACCAGTCAAGAAACTGCTGGGTGAACTGCTGGTTGCCACCAGCC
TGCTGACCGCAACGTTGAAGTTTGACGGCGACATCACCGTCCAGTTACAAGGCGACGGTCCGCTGAAGCTGGCGGTGATT
AACGGTAACAACCGCCAGGAAATGCGTGGCGTAGCTCGCGTACAGAGCGAAATTGCTGATGACAGCACGCTGCACCAGAT
GATCGGCAATGGCGTCATGGTGATCACCATCGCCCCCACCGAGGGCGAACGCTATCAGGGCGTAGTGGCGCTGGAAGGGG
AAACGCTGGCCGAGTGCCTCGAGGCTTACTTCCGTCAGTCAGAGCAGTTGCCTACCCGCCTGTTCATCCGTACCGGTGAG
TCTGAAGGTCAACCGGCCGCGGGTGGCATGCTGCTGCAGGTGCTGCCGGCGCAGGATGGCAATGCCGATGACTTCGATCA
TCTGGTGCAACTGACCAATACGGTGAAAAGCGAAGAGCTGTTCGGCCTGCCGGCCAACGAAGTGCTGTATCGCCTGTATC
ATCAGGAAGAAGTCACCCTGTATGAACCGCAGGACGTTGTCTTCCGTTGCACCTGTTCACGCCAGCGTTGCGCCGATGCG
CTGATCACGCTGCCGGCGGAAGAAGTGGCTCAAATGCTGGAGCAGGACGGCAATATTGATATGCACTGCGATTATTGCGG
CAATCACTATGTCTTCGACGCCATGGACGTAGCCGCGCTGTACACCGGTAACACCGGTGAAAGCGAGCAGTTGCACTAA

Upstream 100 bases:

>100_bases
CCGCATCCGGACCGCCGTCCGGACAAGAAAGAGCGGCGCAACCTGATTAAATTTAAATTTGGTGAGCAGGAATAACCCCT
CACCGCAATGAGAGAAAACT

Downstream 100 bases:

>100_bases
GTAGCACCTTATATCGGCGGGCGCGCCCTGCGCCTGCCGGTTTTCTTCGTTTGCACGTTTGCTTTTTTCCGTGTGCTATC
TCTCATAACGTAACGAAAAA

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSNHDQLHRYLFENYAVRGELVTVSETYQQVLNNHDYPAPVKKLLGELLVATSLLTATLKFDGDITVQLQGDGPLKLAVI
NGNNRQEMRGVARVQSEIADDSTLHQMIGNGVMVITIAPTEGERYQGVVALEGETLAECLEAYFRQSEQLPTRLFIRTGE
SEGQPAAGGMLLQVLPAQDGNADDFDHLVQLTNTVKSEELFGLPANEVLYRLYHQEEVTLYEPQDVVFRCTCSRQRCADA
LITLPAEEVAQMLEQDGNIDMHCDYCGNHYVFDAMDVAALYTGNTGESEQLH

Sequences:

>Translated_292_residues
MSNHDQLHRYLFENYAVRGELVTVSETYQQVLNNHDYPAPVKKLLGELLVATSLLTATLKFDGDITVQLQGDGPLKLAVI
NGNNRQEMRGVARVQSEIADDSTLHQMIGNGVMVITIAPTEGERYQGVVALEGETLAECLEAYFRQSEQLPTRLFIRTGE
SEGQPAAGGMLLQVLPAQDGNADDFDHLVQLTNTVKSEELFGLPANEVLYRLYHQEEVTLYEPQDVVFRCTCSRQRCADA
LITLPAEEVAQMLEQDGNIDMHCDYCGNHYVFDAMDVAALYTGNTGESEQLH
>Mature_291_residues
SNHDQLHRYLFENYAVRGELVTVSETYQQVLNNHDYPAPVKKLLGELLVATSLLTATLKFDGDITVQLQGDGPLKLAVIN
GNNRQEMRGVARVQSEIADDSTLHQMIGNGVMVITIAPTEGERYQGVVALEGETLAECLEAYFRQSEQLPTRLFIRTGES
EGQPAAGGMLLQVLPAQDGNADDFDHLVQLTNTVKSEELFGLPANEVLYRLYHQEEVTLYEPQDVVFRCTCSRQRCADAL
ITLPAEEVAQMLEQDGNIDMHCDYCGNHYVFDAMDVAALYTGNTGESEQLH

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family

Homologues:

Organism=Escherichia coli, GI87082260, Length=292, Percent_Identity=72.6027397260274, Blast_Score=454, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HSLO_SERP5 (A8GKR9)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480837.1
- ProteinModelPortal:   A8GKR9
- SMR:   A8GKR9
- STRING:   A8GKR9
- GeneID:   5604730
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4616
- eggNOG:   COG1281
- HOGENOM:   HBG296531
- OMA:   AMTIDQG
- ProtClustDB:   PRK00114
- BioCyc:   SPRO399741:SPRO_4616-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00117
- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153
- InterPro:   IPR023212
- Gene3D:   G3DSA:1.10.287.480
- Gene3D:   G3DSA:3.90.1280.10
- Gene3D:   G3DSA:3.55.30.10
- PIRSF:   PIRSF005261

Pfam domain/function: PF01430 HSP33; SSF64397 Heat_shock_Hsp33_N

EC number: NA

Molecular weight: Translated: 32456; Mature: 32325

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNHDQLHRYLFENYAVRGELVTVSETYQQVLNNHDYPAPVKKLLGELLVATSLLTATLK
CCCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEE
FDGDITVQLQGDGPLKLAVINGNNRQEMRGVARVQSEIADDSTLHQMIGNGVMVITIAPT
ECCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEECC
EGERYQGVVALEGETLAECLEAYFRQSEQLPTRLFIRTGESEGQPAAGGMLLQVLPAQDG
CCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCC
NADDFDHLVQLTNTVKSEELFGLPANEVLYRLYHQEEVTLYEPQDVVFRCTCSRQRCADA
CCCHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCEEEECCCCEEEEEECCHHHHHHH
LITLPAEEVAQMLEQDGNIDMHCDYCGNHYVFDAMDVAALYTGNTGESEQLH
HEECCHHHHHHHHHCCCCEEEEEECCCCEEEEECHHEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SNHDQLHRYLFENYAVRGELVTVSETYQQVLNNHDYPAPVKKLLGELLVATSLLTATLK
CCHHHHHHHHHHHHCCCCEEEEHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHEEE
FDGDITVQLQGDGPLKLAVINGNNRQEMRGVARVQSEIADDSTLHQMIGNGVMVITIAPT
ECCEEEEEEECCCCEEEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEECC
EGERYQGVVALEGETLAECLEAYFRQSEQLPTRLFIRTGESEGQPAAGGMLLQVLPAQDG
CCCCCCCEEEECCHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCEEEEEEECCCC
NADDFDHLVQLTNTVKSEELFGLPANEVLYRLYHQEEVTLYEPQDVVFRCTCSRQRCADA
CCCHHHHHHHHHHHHCHHHHCCCCHHHHHHHHHHCCCEEEECCCCEEEEEECCHHHHHHH
LITLPAEEVAQMLEQDGNIDMHCDYCGNHYVFDAMDVAALYTGNTGESEQLH
HEECCHHHHHHHHHCCCCEEEEEECCCCEEEEECHHEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA