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The map label for this gene is gph [C]

Identifier: 157372832

GI number: 157372832

Start: 5075523

End: 5076221

Strand: Reverse

Name: gph [C]

Synonym: Spro_4600

Alternate gene names: 157372832

Gene position: 5076221-5075523 (Counterclockwise)

Preceding gene: 157372833

Following gene: 157372831

Centisome position: 93.16

GC content: 60.66

Gene sequence:

>699_bases
ATGGCTGATTTTGGAGCCATCCGCGCTCTGGCTTTCGATCTCGATGGCACGCTGGTAGACAGCGCGCCGGGGTTGGCTGC
CGCTATCGATCTGGCCTTGGCGGAAATGGGCCTGCCGCAGGCCGGTGAGGCCCGGGTTGGCACCTGGATTGGCAACGGCG
CCGACGTGCTGGTACAGCGTGCGCTGCGCTGGGCAGAAGTGGAAGCCACGCCGGAGCACTGCGGGCAACTGCGCGAGCGC
TTCGATCATTTCTATGCGCAAACCGTCGACAGCGGCAGTCGCCTGTTCCCACAGGTGAAAGAAACCCTGGCTCAACTGGC
TGCGCAAAATTACCCGATGGCGCTGGTGACCAACAAGCCAACGCCGTTTGTTGCGCCGTTGCTGGCCGCATTGGGCATTA
TTGATTACTTCTCGCTGATTATCGGCGGTGACGACGTGGTGGAAAAGAAACCGCACCCGGCGCCGCTGTATCTGGTCCTC
GGCAAGCTTGGCCTGCGCGCCAACGAGTTGCTGTTTGTCGGCGACTCCCGCAATGATATTCAGGCGGCACAGGGGGCAGG
TTGCCCAAGCGCCGCGCTGACTTACGGTTATAACTACGGCGAGGCCATTGCCCTGAGCCATCCCGACCGCGTGTTGGAGC
GCTTTGCCGATTTGTTGCCCGCTCTTGGGCTGTCATCTTTAGAGAATCAGGAAATTTAA

Upstream 100 bases:

>100_bases
GCCGGTGCGGACATGTTTGTCGCAGGTTCCGCCATCTTCAGCAAGCCGGATTATCGTCGGGTGATCGACGAAATGCGCAG
CGAGTTGGCGAAGGTGACGC

Downstream 100 bases:

>100_bases
ACATGAGTAAGCCCATCGTATTTAGCGGCGCGCAACCGTCCGGTGAACTGACCATTGGCAACTACATGGGTGCACTGCGT
CAGTGGGAAAAAATGCAGGA

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 232; Mature: 231

Protein sequence:

>232_residues
MADFGAIRALAFDLDGTLVDSAPGLAAAIDLALAEMGLPQAGEARVGTWIGNGADVLVQRALRWAEVEATPEHCGQLRER
FDHFYAQTVDSGSRLFPQVKETLAQLAAQNYPMALVTNKPTPFVAPLLAALGIIDYFSLIIGGDDVVEKKPHPAPLYLVL
GKLGLRANELLFVGDSRNDIQAAQGAGCPSAALTYGYNYGEAIALSHPDRVLERFADLLPALGLSSLENQEI

Sequences:

>Translated_232_residues
MADFGAIRALAFDLDGTLVDSAPGLAAAIDLALAEMGLPQAGEARVGTWIGNGADVLVQRALRWAEVEATPEHCGQLRER
FDHFYAQTVDSGSRLFPQVKETLAQLAAQNYPMALVTNKPTPFVAPLLAALGIIDYFSLIIGGDDVVEKKPHPAPLYLVL
GKLGLRANELLFVGDSRNDIQAAQGAGCPSAALTYGYNYGEAIALSHPDRVLERFADLLPALGLSSLENQEI
>Mature_231_residues
ADFGAIRALAFDLDGTLVDSAPGLAAAIDLALAEMGLPQAGEARVGTWIGNGADVLVQRALRWAEVEATPEHCGQLRERF
DHFYAQTVDSGSRLFPQVKETLAQLAAQNYPMALVTNKPTPFVAPLLAALGIIDYFSLIIGGDDVVEKKPHPAPLYLVLG
KLGLRANELLFVGDSRNDIQAAQGAGCPSAALTYGYNYGEAIALSHPDRVLERFADLLPALGLSSLENQEI

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=248, Percent_Identity=58.4677419354839, Blast_Score=280, Evalue=5e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 24741; Mature: 24610

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFGAIRALAFDLDGTLVDSAPGLAAAIDLALAEMGLPQAGEARVGTWIGNGADVLVQR
CCCHHHHHHHEECCCCCEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHH
ALRWAEVEATPEHCGQLRERFDHFYAQTVDSGSRLFPQVKETLAQLAAQNYPMALVTNKP
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
TPFVAPLLAALGIIDYFSLIIGGDDVVEKKPHPAPLYLVLGKLGLRANELLFVGDSRNDI
CCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHEEHHHCCCCCCEEEECCCCCCH
QAAQGAGCPSAALTYGYNYGEAIALSHPDRVLERFADLLPALGLSSLENQEI
HHHCCCCCCHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
ADFGAIRALAFDLDGTLVDSAPGLAAAIDLALAEMGLPQAGEARVGTWIGNGADVLVQR
CCHHHHHHHEECCCCCEECCCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHH
ALRWAEVEATPEHCGQLRERFDHFYAQTVDSGSRLFPQVKETLAQLAAQNYPMALVTNKP
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEECCC
TPFVAPLLAALGIIDYFSLIIGGDDVVEKKPHPAPLYLVLGKLGLRANELLFVGDSRNDI
CCHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCHHHHEEHHHCCCCCCEEEECCCCCCH
QAAQGAGCPSAALTYGYNYGEAIALSHPDRVLERFADLLPALGLSSLENQEI
HHHCCCCCCHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA