Click here to switch to the map view.

The map label for this gene is codA [H]

Identifier: 157372826

GI number: 157372826

Start: 5067736

End: 5069004

Strand: Reverse

Name: codA [H]

Synonym: Spro_4594

Alternate gene names: 157372826

Gene position: 5069004-5067736 (Counterclockwise)

Preceding gene: 157372831

Following gene: 157372821

Centisome position: 93.03

GC content: 59.42

Gene sequence:

>1269_bases
TTGAAGTTTATCGATAACCTGCGTCTGAGCGGGCATGAAGGGCTGTGGCAATTGGCCATTGAGCTGGGGCGCATCGCCCA
TATCGTGCCGCAGCCGGAAGGGCGGGAATGGCGCAGCGACGTGCTGGATGCACAGGGCGGGCTGGCGCTGCCGGCGTTTG
TCGAACCGCATATCCATCTGGATACCACCCAGACCGCCGGGCAACCGGCCTGGAACCAGTCAGGCACCCTGTTTGAAGGC
ATTGAGCGCTGGGCCGAGCGCAAGGCGCTTCTGACCCACGAGGACGTCAAACAACGCGCCTGGCAGACGCTGAAATGGCA
GATCGCCAACGGCGTACAGTACGTGCGTACCCACGTTGACGTTTCTGACCCGACCCTGACCGCGCTACGTGCGATGCTGG
AAGTGAAACAGGAAGTCGCACCCTGGGTCACGCTGCAAATCGTCGCTTTTCCACAGGAAGGCATTATGTCTTATCCCAAC
GGCGAGACGCTGTTGGAAGAGGCGCTGCGGCTGGGCGCTGACGTGGTAGGAGCCATTCCGCACTTTGAGTTTACGCGCGA
GTACGGCGTGGAGTCCCTGCACAAGGCATTCGCCCTGGCGCAGAAATACGATCGGCTGGTGGATGTTCACTGTGATGAGA
TAGACGACGAACAGTCGCGCTTTGTCGAAACCGTGGCGGCGCTGGCGCTGAAGCTGGATATGGGCGCCAGGGTCACCGCC
AGTCACACCACGGCGATGCATTCCTACAATGGGGCTTACACTTCACGGCTGTTCCGCCTGCTGAAAATGTCCGGCATCAA
CTTTGTCGCTAACCCTTTGGTCAATATTCACCTGCAGGGCCGCTTCGACAGCTACCCGAAACGGCGCGGCATCACCCGGG
TGAAGGAGATGCTGGAGGCGGAAATTAACGTCTGCTTCGGCCATGATGATGTGTTCGATCCCTGGTACCCGCTGGGCACT
GCCAATATGCTGCAGGTGCTGCATATGGGGCTGCACGTGTGCCAACTGATGGGATATGGCCAGATCGACGACGGGCTGAA
ACTGATCACCAGCCACAGTGCACGAACTCTGAACCTGAGCGACTATGGCTTGAAGGCTGGCAACAGCGCCAATCTGGTGA
TATTACCGGCCGATAGCGGCTTTGATGCGGTGCGCCGACAGACGCCGGTGCGTTACTCGATACGTCAGGGCACGGTGATT
GCCGAAACCCAGCCGGCAGAAACCACGCTGTATCTGGCGCAGGATGAGAAGGTGGATTTCCGGCGTTGA

Upstream 100 bases:

>100_bases
GGGGTAATAAATTATTGGCGTCTTTGTCAGTAGGATGAGCTGCCAGTATGATGAATGAAACAGGCTGGAACAGCAGAGGT
GAAGGGTGGCCAAGAGTCCA

Downstream 100 bases:

>100_bases
GCTGGGGGTTATCAGCATAAAAAAGGGCGCCGAGGCGCCCTTTTCATATCACGTCATTGACGACAGATCAGTGGGTCACG
TGACCGTGGCTGCGGTGCTT

Product: cytosine deaminase

Products: NA

Alternate protein names: Cytosine aminohydrolase [H]

Number of amino acids: Translated: 422; Mature: 422

Protein sequence:

>422_residues
MKFIDNLRLSGHEGLWQLAIELGRIAHIVPQPEGREWRSDVLDAQGGLALPAFVEPHIHLDTTQTAGQPAWNQSGTLFEG
IERWAERKALLTHEDVKQRAWQTLKWQIANGVQYVRTHVDVSDPTLTALRAMLEVKQEVAPWVTLQIVAFPQEGIMSYPN
GETLLEEALRLGADVVGAIPHFEFTREYGVESLHKAFALAQKYDRLVDVHCDEIDDEQSRFVETVAALALKLDMGARVTA
SHTTAMHSYNGAYTSRLFRLLKMSGINFVANPLVNIHLQGRFDSYPKRRGITRVKEMLEAEINVCFGHDDVFDPWYPLGT
ANMLQVLHMGLHVCQLMGYGQIDDGLKLITSHSARTLNLSDYGLKAGNSANLVILPADSGFDAVRRQTPVRYSIRQGTVI
AETQPAETTLYLAQDEKVDFRR

Sequences:

>Translated_422_residues
MKFIDNLRLSGHEGLWQLAIELGRIAHIVPQPEGREWRSDVLDAQGGLALPAFVEPHIHLDTTQTAGQPAWNQSGTLFEG
IERWAERKALLTHEDVKQRAWQTLKWQIANGVQYVRTHVDVSDPTLTALRAMLEVKQEVAPWVTLQIVAFPQEGIMSYPN
GETLLEEALRLGADVVGAIPHFEFTREYGVESLHKAFALAQKYDRLVDVHCDEIDDEQSRFVETVAALALKLDMGARVTA
SHTTAMHSYNGAYTSRLFRLLKMSGINFVANPLVNIHLQGRFDSYPKRRGITRVKEMLEAEINVCFGHDDVFDPWYPLGT
ANMLQVLHMGLHVCQLMGYGQIDDGLKLITSHSARTLNLSDYGLKAGNSANLVILPADSGFDAVRRQTPVRYSIRQGTVI
AETQPAETTLYLAQDEKVDFRR
>Mature_422_residues
MKFIDNLRLSGHEGLWQLAIELGRIAHIVPQPEGREWRSDVLDAQGGLALPAFVEPHIHLDTTQTAGQPAWNQSGTLFEG
IERWAERKALLTHEDVKQRAWQTLKWQIANGVQYVRTHVDVSDPTLTALRAMLEVKQEVAPWVTLQIVAFPQEGIMSYPN
GETLLEEALRLGADVVGAIPHFEFTREYGVESLHKAFALAQKYDRLVDVHCDEIDDEQSRFVETVAALALKLDMGARVTA
SHTTAMHSYNGAYTSRLFRLLKMSGINFVANPLVNIHLQGRFDSYPKRRGITRVKEMLEAEINVCFGHDDVFDPWYPLGT
ANMLQVLHMGLHVCQLMGYGQIDDGLKLITSHSARTLNLSDYGLKAGNSANLVILPADSGFDAVRRQTPVRYSIRQGTVI
AETQPAETTLYLAQDEKVDFRR

Specific function: Unknown

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786531, Length=422, Percent_Identity=82.4644549763033, Blast_Score=732, Evalue=0.0,
Organism=Escherichia coli, GI1786517, Length=377, Percent_Identity=24.6684350132626, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013108
- InterPro:   IPR011059 [H]

Pfam domain/function: PF07969 Amidohydro_3 [H]

EC number: =3.5.4.1 [H]

Molecular weight: Translated: 47380; Mature: 47380

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDNLRLSGHEGLWQLAIELGRIAHIVPQPEGREWRSDVLDAQGGLALPAFVEPHIHL
CCCHHCCCCCCCCHHHHHHHHHHHHHEECCCCCCCHHHHHHHCCCCCEECCCCCCCCEEE
DTTQTAGQPAWNQSGTLFEGIERWAERKALLTHEDVKQRAWQTLKWQIANGVQYVRTHVD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHCCC
VSDPTLTALRAMLEVKQEVAPWVTLQIVAFPQEGIMSYPNGETLLEEALRLGADVVGAIP
CCCHHHHHHHHHHHHHHHHCCEEEEEEEEECHHCCCCCCCCHHHHHHHHHHCCHHHHCCC
HFEFTREYGVESLHKAFALAQKYDRLVDVHCDEIDDEQSRFVETVAALALKLDMGARVTA
CHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
SHTTAMHSYNGAYTSRLFRLLKMSGINFVANPLVNIHLQGRFDSYPKRRGITRVKEMLEA
CHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCHHCCHHHHHHHHHH
EINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYGQIDDGLKLITSHSARTLNLS
HHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEECH
DYGLKAGNSANLVILPADSGFDAVRRQTPVRYSIRQGTVIAETQPAETTLYLAQDEKVDF
HCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEECCCEEEEECCCCCEEEEEEECCCCCC
RR
CC
>Mature Secondary Structure
MKFIDNLRLSGHEGLWQLAIELGRIAHIVPQPEGREWRSDVLDAQGGLALPAFVEPHIHL
CCCHHCCCCCCCCHHHHHHHHHHHHHEECCCCCCCHHHHHHHCCCCCEECCCCCCCCEEE
DTTQTAGQPAWNQSGTLFEGIERWAERKALLTHEDVKQRAWQTLKWQIANGVQYVRTHVD
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHCCC
VSDPTLTALRAMLEVKQEVAPWVTLQIVAFPQEGIMSYPNGETLLEEALRLGADVVGAIP
CCCHHHHHHHHHHHHHHHHCCEEEEEEEEECHHCCCCCCCCHHHHHHHHHHCCHHHHCCC
HFEFTREYGVESLHKAFALAQKYDRLVDVHCDEIDDEQSRFVETVAALALKLDMGARVTA
CHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
SHTTAMHSYNGAYTSRLFRLLKMSGINFVANPLVNIHLQGRFDSYPKRRGITRVKEMLEA
CHHHHHHCCCCHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCHHCCHHHHHHHHHH
EINVCFGHDDVFDPWYPLGTANMLQVLHMGLHVCQLMGYGQIDDGLKLITSHSARTLNLS
HHEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEEECH
DYGLKAGNSANLVILPADSGFDAVRRQTPVRYSIRQGTVIAETQPAETTLYLAQDEKVDF
HCCCCCCCCCCEEEEECCCCHHHHHHCCCCEEEECCCEEEEECCCCCEEEEEEECCCCCC
RR
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1640834; 8450832; 9278503 [H]