| Definition | Serratia proteamaculans 568 chromosome, complete genome. |
|---|---|
| Accession | NC_009832 |
| Length | 5,448,853 |
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The map label for this gene is uvrA [H]
Identifier: 157372673
GI number: 157372673
Start: 4912520
End: 4915351
Strand: Direct
Name: uvrA [H]
Synonym: Spro_4440
Alternate gene names: 157372673
Gene position: 4912520-4915351 (Clockwise)
Preceding gene: 157372671
Following gene: 157372674
Centisome position: 90.16
GC content: 59.64
Gene sequence:
>2832_bases ATGGACAATATCGAAGTTCGTGGTGCTCGGACCCATAATCTCAAAAACATCAACCTGATTATCCCGCGTGACAAGCTGAT CGTCGTCACCGGTTTATCCGGTTCAGGCAAGTCCTCGCTGGCTTTTGATACTCTGTATGCCGAAGGGCAGCGTCGCTACG TCGAGTCGCTCTCCGCCTATGCACGCCAGTTCCTCTCGCTGATGGAAAAACCGGACGTCGACCACATTGAAGGCCTGTCT CCGGCGATCTCCATCGAGCAGAAATCGACCTCACATAACCCGCGATCTACGGTCGGCACCATTACCGAGATCCACGATTA CCTGCGCCTGTTGTTTGCCCGCGTCGGCGAACCGCGCTGCCCGGAGCACCATGTGCCGCTGGCGGCGCAAACCGTCAGCC AAATGGTGGACAACGTGCTCAACCAGCCGGAAGGCAAACGCCTGATGCTGCTGGCACCGGTGGTAAAAGACCGCAAGGGC GAGCATACCAAAACGCTGGAAAATCTGGCCACCCAGGGCTATATCCGAGCGCGTATCGACGGTGAAGTCTGCGATCTTTC CGATCCGCCAAAATTGGAGCTGCAGAAGAAGCACACTATCGAAGTGGTGGTCGATCGCTTCAAGGTGCGTGACGATATGT CGCAGCGTCTGGCGGAATCGTTCGAGACCGCGCTGGAGCTGTCCGGCGGCACGGCCGTCGTTGCCGACATGGACGACGAG AAGGCCGATGAGTTGCTGTTCTCCGCCAACTTCGCCTGCCCCATCTGCGGCTACAGCATGCGCGAGCTGGAACCGCGGCT GTTCTCGTTCAACAACCCGGCCGGTGCCTGCCCGACCTGTGACGGCCTGGGCGTGCAGCAGTTCTTCGATCCGGAACGTG TGGTACAGAACCCTGAGCTTTCGCTGGCCGGCGGTGCGATCCGCGGCTGGGATCGCCGTAACTTCTATTACTTCCAGATG CTGCGCTCGTTGTCGGAGCATTACGCGTTTGACGTCGAAGCGCCGTTCAACAGCCTGGATGCCAACGTGCAGAAAGCGGT GCTCAGCGGTTCCGGCAAAGAAACCATCGAATTCAAATATATCAACGATCGCGGTGATACCACCGTGCGCCGCCATCCGT TCGAAGGCGTGCTGCACAATATGGAACGCCGCTATAAAGAAACCGAATCGAGCGCGGTACGCGAAGAGCTGGCCAAGTTT ATCAGCAACCGTCCTTGCGCCTCGTGCCACGGCACCCGCCTGCGTGAAGAAGCGCGCAACGTGTTCGTTGAAGACACCAC GCTGCCGGAAATCTCCGATCTGAGCATCGGCCACGCCATGAGCTTCTTCCAGAACATGAAGCTCAGCGGCCAACGCGCCC AGATTGCCGAGAAAGTGCTGAAAGAAATTGGCGATCGCCTTAAGTTCCTGGTGAACGTCGGCCTGAACTACCTGTCGCTG TCACGCTCGGCGGAAACCCTGTCCGGCGGTGAGGCACAGCGTATCCGTCTGGCCAGCCAGATTGGTGCCGGTTTGGTGGG CGTAATGTACGTACTGGACGAGCCGTCAATCGGCCTGCATCAGCGCGACAACGAACGCCTGCTGGAAACGCTGATCCACC TGCGCAACCTCGGTAACACGGTGATCGTGGTTGAGCATGACGAAGACGCCATCCGCGCCGCCGATCACGTGATCGACATC GGCCCCGGTGCCGGGGTGCATGGCGGTCAGGTGGTGGCAGAAGGTACCGTCGAAGACATCATGGCGCAGCCGGAATCACT GACCGGCCAGTTCCTCAGCGGCAAACGTGGGATTGCCATTCCTGAGCAACGTGTACCGGCCGATCCGACCAAGGTGCTGA AACTGAGCGGCGCACGCGGCAACAACCTGAAAGACGTGACGCTGACGCTGCCGGTGGGGCTGTTTACCTGTATTACCGGG GTTTCCGGCTCGGGCAAGTCAACGCTGATCAACGACACGCTGTTCCCAATCGCCCAGCGCCAGCTCAACGGCGCCACCCT GGCCGAACCTGCACCTTTCCGCGAAGTGACCGGTCTGGAGCATTTCGACAAGGTGATCGACATCGATCAAAGCCCGATCG GTCGGACTCCACGTTCCAACCCGGCGACTTACACCGGCATCTTCACCCCGGTGCGTGAACTGTTCGCCGGCGTACCTGAG TCGCGTAGCCGCGGCTACAACCCAGGCCGCTTCAGTTTTAACGTCAAAGGCGGCCGCTGCGAGGCCTGTCAGGGCGACGG CGTGATCAAGGTGGAAATGCACTTCCTGCCGGATATCTACGTGCCGTGCGACCACTGTAAAGGCAAGCGCTATAACCGCG AAACGCTGGAAGTGAAGTACAAAGGCAAAAGCATTCACGAAGTGCTGGAGATGACCATCGAAGAGGCGCGTGAATTCTTC GACGCGGTGCCGGCATTGGCGCGCAAACTGCAAACCTTGATGGAAGTGGGCCTGTCGTACATCCGTCTCGGCCAGTCGGC CACCACGCTGTCCGGCGGCGAGGCGCAACGCGTCAAGCTGGCACGTGAGCTGTCGAAACGCGGTACCGGCCAAACGCTGT ATATCCTGGATGAGCCGACCACCGGTCTGCACTTCGCCGATATCCAGCAACTGCTGGCGGTGCTGCATCAGCTGCGCGAC CAGGGCAATACCATCGTGGTGATTGAGCACAATCTGGACGTGATTAAAACCGCGGACTGGATCGTCGACCTGGGGCCGGA AGGCGGCAGCGGCGGCGGTGAAATCCTGGTGGCCGGCACGCCAGAAACCGTGGCCAACTGCGAAGCTTCACATACCGCGC GCTTCCTCAAGCCGTTACTGAAGAAGAAGTAA
Upstream 100 bases:
>100_bases CGTTTCGTACTGGCTGTGCCGGTTTTTTGCGCGTTCGATCACAAAATCGTCCGTAAATCACCCAGACAGGCGCGGTGTAT CATCAAGACGGGAAGTGTAA
Downstream 100 bases:
>100_bases TCCCTGCCCGGCGGGCCGTTCCTGTAGCGGCCCGCGCTATTACCTGTTTCGCTCAAATTGAACAGAAACAGGCAAGATTT AGACATTTTCAGGCATTTCC
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 943; Mature: 943
Protein sequence:
>943_residues MDNIEVRGARTHNLKNINLIIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPEHHVPLAAQTVSQMVDNVLNQPEGKRLMLLAPVVKDRKG EHTKTLENLATQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDMSQRLAESFETALELSGGTAVVADMDDE KADELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQFFDPERVVQNPELSLAGGAIRGWDRRNFYYFQM LRSLSEHYAFDVEAPFNSLDANVQKAVLSGSGKETIEFKYINDRGDTTVRRHPFEGVLHNMERRYKETESSAVREELAKF ISNRPCASCHGTRLREEARNVFVEDTTLPEISDLSIGHAMSFFQNMKLSGQRAQIAEKVLKEIGDRLKFLVNVGLNYLSL SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLETLIHLRNLGNTVIVVEHDEDAIRAADHVIDI GPGAGVHGGQVVAEGTVEDIMAQPESLTGQFLSGKRGIAIPEQRVPADPTKVLKLSGARGNNLKDVTLTLPVGLFTCITG VSGSGKSTLINDTLFPIAQRQLNGATLAEPAPFREVTGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPVRELFAGVPE SRSRGYNPGRFSFNVKGGRCEACQGDGVIKVEMHFLPDIYVPCDHCKGKRYNRETLEVKYKGKSIHEVLEMTIEEAREFF DAVPALARKLQTLMEVGLSYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLAVLHQLRD QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVAGTPETVANCEASHTARFLKPLLKKK
Sequences:
>Translated_943_residues MDNIEVRGARTHNLKNINLIIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPEHHVPLAAQTVSQMVDNVLNQPEGKRLMLLAPVVKDRKG EHTKTLENLATQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDMSQRLAESFETALELSGGTAVVADMDDE KADELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQFFDPERVVQNPELSLAGGAIRGWDRRNFYYFQM LRSLSEHYAFDVEAPFNSLDANVQKAVLSGSGKETIEFKYINDRGDTTVRRHPFEGVLHNMERRYKETESSAVREELAKF ISNRPCASCHGTRLREEARNVFVEDTTLPEISDLSIGHAMSFFQNMKLSGQRAQIAEKVLKEIGDRLKFLVNVGLNYLSL SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLETLIHLRNLGNTVIVVEHDEDAIRAADHVIDI GPGAGVHGGQVVAEGTVEDIMAQPESLTGQFLSGKRGIAIPEQRVPADPTKVLKLSGARGNNLKDVTLTLPVGLFTCITG VSGSGKSTLINDTLFPIAQRQLNGATLAEPAPFREVTGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPVRELFAGVPE SRSRGYNPGRFSFNVKGGRCEACQGDGVIKVEMHFLPDIYVPCDHCKGKRYNRETLEVKYKGKSIHEVLEMTIEEAREFF DAVPALARKLQTLMEVGLSYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLAVLHQLRD QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVAGTPETVANCEASHTARFLKPLLKKK >Mature_943_residues MDNIEVRGARTHNLKNINLIIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLS PAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRCPEHHVPLAAQTVSQMVDNVLNQPEGKRLMLLAPVVKDRKG EHTKTLENLATQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDMSQRLAESFETALELSGGTAVVADMDDE KADELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQFFDPERVVQNPELSLAGGAIRGWDRRNFYYFQM LRSLSEHYAFDVEAPFNSLDANVQKAVLSGSGKETIEFKYINDRGDTTVRRHPFEGVLHNMERRYKETESSAVREELAKF ISNRPCASCHGTRLREEARNVFVEDTTLPEISDLSIGHAMSFFQNMKLSGQRAQIAEKVLKEIGDRLKFLVNVGLNYLSL SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLETLIHLRNLGNTVIVVEHDEDAIRAADHVIDI GPGAGVHGGQVVAEGTVEDIMAQPESLTGQFLSGKRGIAIPEQRVPADPTKVLKLSGARGNNLKDVTLTLPVGLFTCITG VSGSGKSTLINDTLFPIAQRQLNGATLAEPAPFREVTGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPVRELFAGVPE SRSRGYNPGRFSFNVKGGRCEACQGDGVIKVEMHFLPDIYVPCDHCKGKRYNRETLEVKYKGKSIHEVLEMTIEEAREFF DAVPALARKLQTLMEVGLSYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYILDEPTTGLHFADIQQLLAVLHQLRD QGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGEILVAGTPETVANCEASHTARFLKPLLKKK
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=940, Percent_Identity=91.2765957446809, Blast_Score=1774, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 103980; Mature: 103980
Theoretical pI: Translated: 6.33; Mature: 6.33
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.5 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 1.5 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDNIEVRGARTHNLKNINLIIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAY CCCCEECCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHH ARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRC HHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PEHHVPLAAQTVSQMVDNVLNQPEGKRLMLLAPVVKDRKGEHTKTLENLATQGYIRARID CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCCHHHHHHHHHHCCEEEEEEC GEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDMSQRLAESFETALELSGGTAVVADMDDE CCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC KADELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQFFDPERVVQNPEL HHHHHHHCCCCCCCCCCCHHHHCCCHHEECCCCCCCCCCCCCCCHHHHCCHHHHHCCCCC SLAGGAIRGWDRRNFYYFQMLRSLSEHYAFDVEAPFNSLDANVQKAVLSGSGKETIEFKY EECCCCCCCCCCCCHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEE INDRGDTTVRRHPFEGVLHNMERRYKETESSAVREELAKFISNRPCASCHGTRLREEARN ECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHC VFVEDTTLPEISDLSIGHAMSFFQNMKLSGQRAQIAEKVLKEIGDRLKFLVNVGLNYLSL EEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLETLIHLRNLGNT CCCHHHCCCCCHHHHHHHHHHCCHHEEHHHEECCCCCCCCCCCHHHHHHHHHHHHCCCCE VIVVEHDEDAIRAADHVIDIGPGAGVHGGQVVAEGTVEDIMAQPESLTGQFLSGKRGIAI EEEEECCCHHHHHHHCEEECCCCCCCCCCEEEECCCHHHHHCCCHHHHHHHHCCCCCCCC PEQRVPADPTKVLKLSGARGNNLKDVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQR CCCCCCCCCHHEEEECCCCCCCCEEEEEEEHHHHHHHHHCCCCCCCCEEECCHHHHHHHH QLNGATLAEPAPFREVTGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPVRELFAGVPE HCCCCCCCCCCCCHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCC SRSRGYNPGRFSFNVKGGRCEACQGDGVIKVEMHFLPDIYVPCDHCKGKRYNRETLEVKY HHHCCCCCCEEEEEECCCEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEE KGKSIHEVLEMTIEEAREFFDAVPALARKLQTLMEVGLSYIRLGQSATTLSGGEAQRVKL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH ARELSKRGTGQTLYILDEPTTGLHFADIQQLLAVLHQLRDQGNTIVVIEHNLDVIKTADW HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCE IVDLGPEGGSGGGEILVAGTPETVANCEASHTARFLKPLLKKK EEEECCCCCCCCCEEEEECCCHHHHCCCHHHHHHHHHHHHCCC >Mature Secondary Structure MDNIEVRGARTHNLKNINLIIPRDKLIVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAY CCCCEECCCCCCCCCEEEEEECCCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHHH ARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTITEIHDYLRLLFARVGEPRC HHHHHHHHCCCCCCHHCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC PEHHVPLAAQTVSQMVDNVLNQPEGKRLMLLAPVVKDRKGEHTKTLENLATQGYIRARID CCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECHHHCCCCCHHHHHHHHHHCCEEEEEEC GEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDMSQRLAESFETALELSGGTAVVADMDDE CCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCC KADELLFSANFACPICGYSMRELEPRLFSFNNPAGACPTCDGLGVQQFFDPERVVQNPEL HHHHHHHCCCCCCCCCCCHHHHCCCHHEECCCCCCCCCCCCCCCHHHHCCHHHHHCCCCC SLAGGAIRGWDRRNFYYFQMLRSLSEHYAFDVEAPFNSLDANVQKAVLSGSGKETIEFKY EECCCCCCCCCCCCHHHHHHHHHHHHHCEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEE INDRGDTTVRRHPFEGVLHNMERRYKETESSAVREELAKFISNRPCASCHGTRLREEARN ECCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHC VFVEDTTLPEISDLSIGHAMSFFQNMKLSGQRAQIAEKVLKEIGDRLKFLVNVGLNYLSL EEEECCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH SRSAETLSGGEAQRIRLASQIGAGLVGVMYVLDEPSIGLHQRDNERLLETLIHLRNLGNT CCCHHHCCCCCHHHHHHHHHHCCHHEEHHHEECCCCCCCCCCCHHHHHHHHHHHHCCCCE VIVVEHDEDAIRAADHVIDIGPGAGVHGGQVVAEGTVEDIMAQPESLTGQFLSGKRGIAI EEEEECCCHHHHHHHCEEECCCCCCCCCCEEEECCCHHHHHCCCHHHHHHHHCCCCCCCC PEQRVPADPTKVLKLSGARGNNLKDVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQR CCCCCCCCCHHEEEECCCCCCCCEEEEEEEHHHHHHHHHCCCCCCCCEEECCHHHHHHHH QLNGATLAEPAPFREVTGLEHFDKVIDIDQSPIGRTPRSNPATYTGIFTPVRELFAGVPE HCCCCCCCCCCCCHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHCCCCC SRSRGYNPGRFSFNVKGGRCEACQGDGVIKVEMHFLPDIYVPCDHCKGKRYNRETLEVKY HHHCCCCCCEEEEEECCCEECCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEE KGKSIHEVLEMTIEEAREFFDAVPALARKLQTLMEVGLSYIRLGQSATTLSGGEAQRVKL CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHH ARELSKRGTGQTLYILDEPTTGLHFADIQQLLAVLHQLRDQGNTIVVIEHNLDVIKTADW HHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCE IVDLGPEGGSGGGEILVAGTPETVANCEASHTARFLKPLLKKK EEEECCCCCCCCCEEEEECCCHHHHCCCHHHHHHHHHHHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11586360; 12142430 [H]