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The map label for this gene is prmA

Identifier: 157372654

GI number: 157372654

Start: 4894598

End: 4895479

Strand: Direct

Name: prmA

Synonym: Spro_4421

Alternate gene names: 157372654

Gene position: 4894598-4895479 (Clockwise)

Preceding gene: 157372653

Following gene: 157372655

Centisome position: 89.83

GC content: 60.77

Gene sequence:

>882_bases
ATGCCTTGGATCCAACTCAAACTGAACACCACCGGCAGCCAGGCAGAAGACCTGAGCGACGCGCTGGTTGAAAGCGGCGC
AGTATCGGTGACCTTTCAGGACACTCACGACAATCCGGTGTTCGAACCGCTGCCGGGCGAAACCCTGCTGTGGGGCGATA
CCGATGTGATCGGACTCTACGACGCTGAAACCGATATGGCCGAAGTGGTGGCAATGCTGGAACAGCATCCACTGCTGGGC
GCCGGTTTCCGCCACAAGATTGAACAGCTGGAAGACAAAGACTGGGAGCGCGAGTGGATGGACAACTTCCACCCGATGCG
TTTCGGCCAGCGTCTGTGGATCTGCCCAAGCTGGCGTGACGTGCCCGATCCGGATGCGGTTAACGTGATGCTCGACCCGG
GCCTGGCGTTCGGTACCGGCACCCACCCGACGACGGCGCTGTGTTTGCAGTGGCTCGATGGTCTGGATCTGGCCGGTAAG
ACCATTATCGACTTCGGTTGTGGTTCCGGCATTCTGGCGATTGCCGCCCTGAAGCTCGGTGCAGCGCGCGCTATCGGTAT
CGATATCGATCCCCAGGCCATTCAGGCCAGTCGCGACAACGCGCAGCGTAACGGCGTTTCAGAGCGTCTGGAGCTGTATC
TGCCAAAAGATCAGCCTGCCGATCTGCTGGCCGACGTCGTGGTCGCCAACATTCTGGCCGGTCCATTGCGTGAGCTGGCA
CCGCTGATTGGCTGCCTGCCGAAATCCGGCGGCCATCTGGGCCTGTCCGGCGTGCTGGCCACCCAGGCAGCGAGCGTGGC
GCAAGCCTATGAAGATAAATTCACGCTCGACCCGGTAGCAGAACGCGAAGAATGGTGCCGCATTACCGGCCAACGCAAGT
AA

Upstream 100 bases:

>100_bases
GCCTTCACTGCTGCTTAGCCTGCTGGCATTTTATATCGGTAACCTCGTCGGCGAAAAACGCCGGACGGCGTCATCATTAC
CCTCTTAAAAGAGAATTGTT

Downstream 100 bases:

>100_bases
TCATATTTTTGTTCCGATAAAAACCACCGATAACTTAACAAGTTACGGTGGTTTTTTTTCGCCCCAAGATTTCACTGATT
TATCCTGACAAAAAGCAGGC

Product: 50S ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MPWIQLKLNTTGSQAEDLSDALVESGAVSVTFQDTHDNPVFEPLPGETLLWGDTDVIGLYDAETDMAEVVAMLEQHPLLG
AGFRHKIEQLEDKDWEREWMDNFHPMRFGQRLWICPSWRDVPDPDAVNVMLDPGLAFGTGTHPTTALCLQWLDGLDLAGK
TIIDFGCGSGILAIAALKLGAARAIGIDIDPQAIQASRDNAQRNGVSERLELYLPKDQPADLLADVVVANILAGPLRELA
PLIGCLPKSGGHLGLSGVLATQAASVAQAYEDKFTLDPVAEREEWCRITGQRK

Sequences:

>Translated_293_residues
MPWIQLKLNTTGSQAEDLSDALVESGAVSVTFQDTHDNPVFEPLPGETLLWGDTDVIGLYDAETDMAEVVAMLEQHPLLG
AGFRHKIEQLEDKDWEREWMDNFHPMRFGQRLWICPSWRDVPDPDAVNVMLDPGLAFGTGTHPTTALCLQWLDGLDLAGK
TIIDFGCGSGILAIAALKLGAARAIGIDIDPQAIQASRDNAQRNGVSERLELYLPKDQPADLLADVVVANILAGPLRELA
PLIGCLPKSGGHLGLSGVLATQAASVAQAYEDKFTLDPVAEREEWCRITGQRK
>Mature_292_residues
PWIQLKLNTTGSQAEDLSDALVESGAVSVTFQDTHDNPVFEPLPGETLLWGDTDVIGLYDAETDMAEVVAMLEQHPLLGA
GFRHKIEQLEDKDWEREWMDNFHPMRFGQRLWICPSWRDVPDPDAVNVMLDPGLAFGTGTHPTTALCLQWLDGLDLAGKT
IIDFGCGSGILAIAALKLGAARAIGIDIDPQAIQASRDNAQRNGVSERLELYLPKDQPADLLADVVVANILAGPLRELAP
LIGCLPKSGGHLGLSGVLATQAASVAQAYEDKFTLDPVAEREEWCRITGQRK

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=293, Percent_Identity=84.9829351535836, Blast_Score=482, Evalue=1e-137,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_SERP5 (A8GK75)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480643.1
- ProteinModelPortal:   A8GK75
- STRING:   A8GK75
- GeneID:   5606335
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4421
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   EREEWCR
- ProtClustDB:   PRK00517
- BioCyc:   SPRO399741:SPRO_4421-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 31872; Mature: 31741

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWIQLKLNTTGSQAEDLSDALVESGAVSVTFQDTHDNPVFEPLPGETLLWGDTDVIGLY
CCEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCEEEEE
DAETDMAEVVAMLEQHPLLGAGFRHKIEQLEDKDWEREWMDNFHPMRFGQRLWICPSWRD
ECCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCHHHCCEEEECCCCCC
VPDPDAVNVMLDPGLAFGTGTHPTTALCLQWLDGLDLAGKTIIDFGCGSGILAIAALKLG
CCCCCCEEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHC
AARAIGIDIDPQAIQASRDNAQRNGVSERLELYLPKDQPADLLADVVVANILAGPLRELA
CCEEEECCCCHHHHHHHHHHHHHCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
PLIGCLPKSGGHLGLSGVLATQAASVAQAYEDKFTLDPVAEREEWCRITGQRK
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PWIQLKLNTTGSQAEDLSDALVESGAVSVTFQDTHDNPVFEPLPGETLLWGDTDVIGLY
CEEEEEECCCCCCHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCEEEECCCCEEEEE
DAETDMAEVVAMLEQHPLLGAGFRHKIEQLEDKDWEREWMDNFHPMRFGQRLWICPSWRD
ECCCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCHHHCCEEEECCCCCC
VPDPDAVNVMLDPGLAFGTGTHPTTALCLQWLDGLDLAGKTIIDFGCGSGILAIAALKLG
CCCCCCEEEEECCCEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHHC
AARAIGIDIDPQAIQASRDNAQRNGVSERLELYLPKDQPADLLADVVVANILAGPLRELA
CCEEEECCCCHHHHHHHHHHHHHCCHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
PLIGCLPKSGGHLGLSGVLATQAASVAQAYEDKFTLDPVAEREEWCRITGQRK
HHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA