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The map label for this gene is xerD [H]

Identifier: 157372126

GI number: 157372126

Start: 4312855

End: 4313754

Strand: Reverse

Name: xerD [H]

Synonym: Spro_3892

Alternate gene names: 157372126

Gene position: 4313754-4312855 (Counterclockwise)

Preceding gene: 157372128

Following gene: 157372125

Centisome position: 79.17

GC content: 57.67

Gene sequence:

>900_bases
GTGCAACAGCAAGAGAGTGCGTTGATTGAGCAATTCCTGGATGCGCTGTGGCTCGAACGTAATCTGGCAGAAAATACGCT
GGCCTCTTACCGATTGGATTTGCAGGCGCTGGGTGCCTGGCTGAATCAGCAAAATACCTCGCTGTTACAGGCACAGGCGC
TGGATTTACAGGCGTTTCTCGCCGATCGGGTGGAGGGAGGATATAAAGCGACCAGCTCCGCACGTTTGCTGAGCGCCATG
CGCCGTCTGTTCCAATACCTGTATCGCGAAAATATGCGTAGTGACGATCCCACGGCACTGCTGGCTTCGCCGAAGCTGCC
GCAGCGCCTGCCGAAAGACTTGAGCGAAGCGCAGGTCGATGCGCTGCTGAAGGCGCCCTGTGTCGATCAGCCGCTGGAGC
TGCGTGACAAGGCGATGCTGGAAGTGCTGTACGCTACCGGGTTGCGCGTCTCCGAACTGGTCGGGCTGACCATCAGCGAT
GTCAGCCTGCGTCAGGGCGTGGTACGGGTGATAGGTAAAGGCAACAAGGAGCGACTGGTGCCGCTGGGTGAAGAAGCGGT
GTACTGGATAGAAAATTATCTGGAGCACGGCCGCCCGTGGATGGTCAACGGCCAGGCGCTGGACGTCTTGTTCCCCAGCA
ACCGCAGCCAGCAAATGACCCGACAGACATTCTGGCATCGCATCAAACACTATGCGATCCTAGCGGGTATTGACAGCGAG
AGGCTGTCGCCGCACGTGTTGCGCCACGCGTTTGCCACCCATTTGCTGAACCATGGGGCCGATCTCCGTGTCGTACAGAT
GTTATTGGGGCATAGCGACCTCTCGACCACACAAATTTACACGCATGTAGCGACCGAAAGACTTAAACAGCTACATCAAC
AGCACCACCCGCGTGCCTGA

Upstream 100 bases:

>100_bases
CCGTTTATATTGCCGTAGGTAGAATTGCAGCGAGTATACCCGATTTGTCCCGGCTTAAGGCATAATGCCTGTGGCATAAA
CGTAACAAAGAGAGGACCGC

Downstream 100 bases:

>100_bases
CATGCCGGGTTCAAAAGGATTGGAAGAATGAAGAAAGGTTTAATGCTGCTCTCTATGCTGGTGGCTTCAGTGACCGGCGC
GGCCCATGCCGACGACGCGG

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MQQQESALIEQFLDALWLERNLAENTLASYRLDLQALGAWLNQQNTSLLQAQALDLQAFLADRVEGGYKATSSARLLSAM
RRLFQYLYRENMRSDDPTALLASPKLPQRLPKDLSEAQVDALLKAPCVDQPLELRDKAMLEVLYATGLRVSELVGLTISD
VSLRQGVVRVIGKGNKERLVPLGEEAVYWIENYLEHGRPWMVNGQALDVLFPSNRSQQMTRQTFWHRIKHYAILAGIDSE
RLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLKQLHQQHHPRA

Sequences:

>Translated_299_residues
MQQQESALIEQFLDALWLERNLAENTLASYRLDLQALGAWLNQQNTSLLQAQALDLQAFLADRVEGGYKATSSARLLSAM
RRLFQYLYRENMRSDDPTALLASPKLPQRLPKDLSEAQVDALLKAPCVDQPLELRDKAMLEVLYATGLRVSELVGLTISD
VSLRQGVVRVIGKGNKERLVPLGEEAVYWIENYLEHGRPWMVNGQALDVLFPSNRSQQMTRQTFWHRIKHYAILAGIDSE
RLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLKQLHQQHHPRA
>Mature_299_residues
MQQQESALIEQFLDALWLERNLAENTLASYRLDLQALGAWLNQQNTSLLQAQALDLQAFLADRVEGGYKATSSARLLSAM
RRLFQYLYRENMRSDDPTALLASPKLPQRLPKDLSEAQVDALLKAPCVDQPLELRDKAMLEVLYATGLRVSELVGLTISD
VSLRQGVVRVIGKGNKERLVPLGEEAVYWIENYLEHGRPWMVNGQALDVLFPSNRSQQMTRQTFWHRIKHYAILAGIDSE
RLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLKQLHQQHHPRA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from xerC binding sites by a short central region, forming

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=297, Percent_Identity=82.8282828282828, Blast_Score=511, Evalue=1e-146,
Organism=Escherichia coli, GI1790244, Length=292, Percent_Identity=38.6986301369863, Blast_Score=188, Evalue=3e-49,
Organism=Escherichia coli, GI1790768, Length=179, Percent_Identity=29.608938547486, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790767, Length=170, Percent_Identity=30, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34009; Mature: 34009

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQQESALIEQFLDALWLERNLAENTLASYRLDLQALGAWLNQQNTSLLQAQALDLQAFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ADRVEGGYKATSSARLLSAMRRLFQYLYRENMRSDDPTALLASPKLPQRLPKDLSEAQVD
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHH
ALLKAPCVDQPLELRDKAMLEVLYATGLRVSELVGLTISDVSLRQGVVRVIGKGNKERLV
HHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
PLGEEAVYWIENYLEHGRPWMVNGQALDVLFPSNRSQQMTRQTFWHRIKHYAILAGIDSE
CCCHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCHH
RLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLKQLHQQHHPRA
HCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQQQESALIEQFLDALWLERNLAENTLASYRLDLQALGAWLNQQNTSLLQAQALDLQAFL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
ADRVEGGYKATSSARLLSAMRRLFQYLYRENMRSDDPTALLASPKLPQRLPKDLSEAQVD
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHH
ALLKAPCVDQPLELRDKAMLEVLYATGLRVSELVGLTISDVSLRQGVVRVIGKGNKERLV
HHHHCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCC
PLGEEAVYWIENYLEHGRPWMVNGQALDVLFPSNRSQQMTRQTFWHRIKHYAILAGIDSE
CCCHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCHHHHHHHHHHHHHHHHHHEECCCHH
RLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLKQLHQQHHPRA
HCCHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]