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The map label for this gene is cdsA [H]

Identifier: 157372019

GI number: 157372019

Start: 4184180

End: 4185028

Strand: Reverse

Name: cdsA [H]

Synonym: Spro_3784

Alternate gene names: 157372019

Gene position: 4185028-4184180 (Counterclockwise)

Preceding gene: 157372020

Following gene: 157372018

Centisome position: 76.81

GC content: 56.07

Gene sequence:

>849_bases
TTGCTGAAGTATCGCCTCATAACTGCTCTGATCTTAATTCCGATTGTTATCGCGGCGCTGTTTTTGCTGCCGCCGGTGGG
CTTTGCCCTGGTAACACTCGTGGTGTGCATGTTAGCGGCCTGGGAGTGGGGCCAGCTGGCCGGATTTACCTCCCGCTCGC
AGCGCATCTGGTTGGCGATATTGTGCGGCTTCCTGCTGGCGTTGATGATGCTCAGTATTCCGGCCTATCATCAGTCGGTC
CATTTACTTCAGGTAGGCGGCTCGCTGTGGCTGTCAATGGCCTGGTGGCTGGTGGCGCTGTTGCTGGTGCTGTTTTATCC
CGGCTCGGCCGCACTGTGGCGTAACTCACGTCCGATACGTCTGGTTTTCGGTCTGCTGACCATAGTGCCGTTCTTCTGGG
GTATGCTATCGCTGCGTCAGTTCGGCTACGAACAAAACCACTTCACCGGCGCCTGGTGGCTGCTGTATGTGATGTTGCTG
GTTTGGGGGGCGGATTCCGGTGCCTACATGTTCGGCAAACTGTTCGGCAAGCATAAGCTGGCACCCAAAGTTTCTCCGGG
GAAAACCTGGGAAGGGCTGGTCGGTGGCCTGATTACTTCGGCCCTGATATCCTGGCTGTTTGGTCGTTATGCCCCGCTCA
ATGTGGTGCCGACAACCTTACTGATTTGTTCGGTGATTGCCGTGCTGGCCTCCGTGCTGGGCGATCTTACCGAGAGCATG
TTCAAACGCGAAGCGGGTATCAAAGACAGCGGTCATTTGATACCGGGTCATGGCGGCATACTGGATCGTATCGATAGCCT
GACCGCAGCAGTGCCTGTATTTGCCTGCCTGATGCTGTTAGTGTTTTAA

Upstream 100 bases:

>100_bases
TGAACTTGTCTTTGAAGGTGCGCTGAATGCATTTGCACAACGCGAGCGTCGCTTCGGGGGAACAACACCTATCGGCGCCA
ATGCGTCCTAGGGGGAACTT

Downstream 100 bases:

>100_bases
TCCGTCAACGGCGGGGAGTGAAGGGATTATGGTTAGCGTGCTCTGGAACTTAGTCGCATTTCTTGTTGCGCTCGGTGTAT
TGATCACCGTGCATGAGTTC

Product: CDP-diglyceride synthase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MLKYRLITALILIPIVIAALFLLPPVGFALVTLVVCMLAAWEWGQLAGFTSRSQRIWLAILCGFLLALMMLSIPAYHQSV
HLLQVGGSLWLSMAWWLVALLLVLFYPGSAALWRNSRPIRLVFGLLTIVPFFWGMLSLRQFGYEQNHFTGAWWLLYVMLL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWEGLVGGLITSALISWLFGRYAPLNVVPTTLLICSVIAVLASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLMLLVF

Sequences:

>Translated_282_residues
MLKYRLITALILIPIVIAALFLLPPVGFALVTLVVCMLAAWEWGQLAGFTSRSQRIWLAILCGFLLALMMLSIPAYHQSV
HLLQVGGSLWLSMAWWLVALLLVLFYPGSAALWRNSRPIRLVFGLLTIVPFFWGMLSLRQFGYEQNHFTGAWWLLYVMLL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWEGLVGGLITSALISWLFGRYAPLNVVPTTLLICSVIAVLASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLMLLVF
>Mature_282_residues
MLKYRLITALILIPIVIAALFLLPPVGFALVTLVVCMLAAWEWGQLAGFTSRSQRIWLAILCGFLLALMMLSIPAYHQSV
HLLQVGGSLWLSMAWWLVALLLVLFYPGSAALWRNSRPIRLVFGLLTIVPFFWGMLSLRQFGYEQNHFTGAWWLLYVMLL
VWGADSGAYMFGKLFGKHKLAPKVSPGKTWEGLVGGLITSALISWLFGRYAPLNVVPTTLLICSVIAVLASVLGDLTESM
FKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFACLMLLVF

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=282, Percent_Identity=78.3687943262411, Blast_Score=438, Evalue=1e-124,
Organism=Escherichia coli, GI1787677, Length=111, Percent_Identity=47.7477477477478, Blast_Score=100, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 31104; Mature: 31104

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]