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The map label for this gene is rseP [H]

Identifier: 157372018

GI number: 157372018

Start: 4182796

End: 4184151

Strand: Reverse

Name: rseP [H]

Synonym: Spro_3783

Alternate gene names: 157372018

Gene position: 4184151-4182796 (Counterclockwise)

Preceding gene: 157372019

Following gene: 157372017

Centisome position: 76.79

GC content: 53.91

Gene sequence:

>1356_bases
ATGGTTAGCGTGCTCTGGAACTTAGTCGCATTTCTTGTTGCGCTCGGTGTATTGATCACCGTGCATGAGTTCGGGCACTT
TTGGGTCGCCCGTCGCTGCGGCGTCCGTGTAGAACGCTTCTCCATTGGCTTTGGCCGCGCCCTGTGGCGTCGTACCGACC
GTCAGGGTACGGAGTACGTTATTGCCCTGATCCCGCTTGGCGGCTACGTGAAGATGCTCGATGAGCGGGTTGATTCGGTC
GCACCGGAACTCCGTCATCAGGCGTTTAACAACAAAACCGTTTGGCAGCGTGCCGCTATCATCAGTGCCGGTCCTATCGC
CAATTTCCTGTTTGCTATCCTTGCTTACTGGCTGGTATTCATTATCGGCGTGCCCAGTTTCCGCCCGGTAATCGGTGAAA
TCGCTCCCCAATCGATTGCAGCCCACGCTGAAATTTCGCCTGGAATGGAACTTAAGTCCGTAGATGGCATCGAAACGCCT
GATTGGGAATCAGTTCGTCTGGCACTGGTGGCGAAGATTGGCGACGCAGAAACCGAGGTGGGTATCGCGCCGTTTGGTTC
TTCCAGTGTGGTGACCAAAACCCTGGATTTGCGCCAGTGGAATTTTGAACCGGACAAACAGGATCCCGTGGTGGCGTTGG
GTATCATTCCGCGCGGCCCGCAGATAGAATCTGTCCTTGCCGAAGTGCAGCCGGGGTCGGCAGCGCAAAAGGCGGGTTTA
CAAGCGGGGGACAGGATCGTTAAAGTCGATGGTCAGTTATTGGGTCGTTGGCAAACGTTGGTGAAACGGATACACAACGG
TCCAGGGCAACCGCTGGCTTTAGAGATCGAAAGAAACGGCGCCCCCTTGTCTTTGACGCTGATACCGGATACAAAGCCGG
TGGGAAAAGACAAATCGGTGGGTTTTGCCGGCATCATTCCGAAAGTGTTGCCGCTGCCGGACGAGTATAAGACGATTCGC
CAGTATGGACCTTTCCCGGCGCTGTATCAGGCCGGGGACAAGACCTGGCAGCTTATGAGCCTTACGGTCAAAATGCTGGG
TAAATTAATAACCGGTGATGTAAAGCTGAACAACCTGAGTGGCCCGATTTCGATTGCACAGGGAGCAGGGGCGTCAGCTG
GGGTCGGGTTTGTGTATTATCTGATGTTTCTGGCGTTGATCAGTGTCAACCTGGGTATCATCAACCTGTTCCCATTACCG
GTGTTAGATGGTGGGCATCTCCTCTTCCTGGCGATAGAAAAGCTGAAGGGTGGGCCGGTTTCCGAGCGAGTACAGGACTA
CAGTTACCGCATAGGTTCGATCGTGTTGGTGCTTTTAATGGGTCTTGCACTTTTCAATGATTTTTCTCGTCTTTAG

Upstream 100 bases:

>100_bases
ATACTGGATCGTATCGATAGCCTGACCGCAGCAGTGCCTGTATTTGCCTGCCTGATGCTGTTAGTGTTTTAATCCGTCAA
CGGCGGGGAGTGAAGGGATT

Downstream 100 bases:

>100_bases
GGGCGGGGATAGGTTAGGAAGAACGCATAACAACGATGGCGATGAAAAAGTTGCTCATAGCGTCGCTGCTGTTTGGCAGC
GCCACCGTATACGGTGCAGA

Product: zinc metallopeptidase RseP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MVSVLWNLVAFLVALGVLITVHEFGHFWVARRCGVRVERFSIGFGRALWRRTDRQGTEYVIALIPLGGYVKMLDERVDSV
APELRHQAFNNKTVWQRAAIISAGPIANFLFAILAYWLVFIIGVPSFRPVIGEIAPQSIAAHAEISPGMELKSVDGIETP
DWESVRLALVAKIGDAETEVGIAPFGSSSVVTKTLDLRQWNFEPDKQDPVVALGIIPRGPQIESVLAEVQPGSAAQKAGL
QAGDRIVKVDGQLLGRWQTLVKRIHNGPGQPLALEIERNGAPLSLTLIPDTKPVGKDKSVGFAGIIPKVLPLPDEYKTIR
QYGPFPALYQAGDKTWQLMSLTVKMLGKLITGDVKLNNLSGPISIAQGAGASAGVGFVYYLMFLALISVNLGIINLFPLP
VLDGGHLLFLAIEKLKGGPVSERVQDYSYRIGSIVLVLLMGLALFNDFSRL

Sequences:

>Translated_451_residues
MVSVLWNLVAFLVALGVLITVHEFGHFWVARRCGVRVERFSIGFGRALWRRTDRQGTEYVIALIPLGGYVKMLDERVDSV
APELRHQAFNNKTVWQRAAIISAGPIANFLFAILAYWLVFIIGVPSFRPVIGEIAPQSIAAHAEISPGMELKSVDGIETP
DWESVRLALVAKIGDAETEVGIAPFGSSSVVTKTLDLRQWNFEPDKQDPVVALGIIPRGPQIESVLAEVQPGSAAQKAGL
QAGDRIVKVDGQLLGRWQTLVKRIHNGPGQPLALEIERNGAPLSLTLIPDTKPVGKDKSVGFAGIIPKVLPLPDEYKTIR
QYGPFPALYQAGDKTWQLMSLTVKMLGKLITGDVKLNNLSGPISIAQGAGASAGVGFVYYLMFLALISVNLGIINLFPLP
VLDGGHLLFLAIEKLKGGPVSERVQDYSYRIGSIVLVLLMGLALFNDFSRL
>Mature_451_residues
MVSVLWNLVAFLVALGVLITVHEFGHFWVARRCGVRVERFSIGFGRALWRRTDRQGTEYVIALIPLGGYVKMLDERVDSV
APELRHQAFNNKTVWQRAAIISAGPIANFLFAILAYWLVFIIGVPSFRPVIGEIAPQSIAAHAEISPGMELKSVDGIETP
DWESVRLALVAKIGDAETEVGIAPFGSSSVVTKTLDLRQWNFEPDKQDPVVALGIIPRGPQIESVLAEVQPGSAAQKAGL
QAGDRIVKVDGQLLGRWQTLVKRIHNGPGQPLALEIERNGAPLSLTLIPDTKPVGKDKSVGFAGIIPKVLPLPDEYKTIR
QYGPFPALYQAGDKTWQLMSLTVKMLGKLITGDVKLNNLSGPISIAQGAGASAGVGFVYYLMFLALISVNLGIINLFPLP
VLDGGHLLFLAIEKLKGGPVSERVQDYSYRIGSIVLVLLMGLALFNDFSRL

Specific function: Degrades both heat shock sigma factors rpoE and rpoH [H]

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=451, Percent_Identity=77.1618625277162, Blast_Score=686, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49027; Mature: 49027

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSVLWNLVAFLVALGVLITVHEFGHFWVARRCGVRVERFSIGFGRALWRRTDRQGTEYV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHCCCCCCEEE
IALIPLGGYVKMLDERVDSVAPELRHQAFNNKTVWQRAAIISAGPIANFLFAILAYWLVF
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IIGVPSFRPVIGEIAPQSIAAHAEISPGMELKSVDGIETPDWESVRLALVAKIGDAETEV
HHCCCCCHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
GIAPFGSSSVVTKTLDLRQWNFEPDKQDPVVALGIIPRGPQIESVLAEVQPGSAAQKAGL
CCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCHHHHCCC
QAGDRIVKVDGQLLGRWQTLVKRIHNGPGQPLALEIERNGAPLSLTLIPDTKPVGKDKSV
CCCCEEEEECHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCC
GFAGIIPKVLPLPDEYKTIRQYGPFPALYQAGDKTWQLMSLTVKMLGKLITGDVKLNNLS
CHHHHCHHHCCCCHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEECCC
GPISIAQGAGASAGVGFVYYLMFLALISVNLGIINLFPLPVLDGGHLLFLAIEKLKGGPV
CCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCEECCCCEEEEEEEHHCCCCH
SERVQDYSYRIGSIVLVLLMGLALFNDFSRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSVLWNLVAFLVALGVLITVHEFGHFWVARRCGVRVERFSIGFGRALWRRTDRQGTEYV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHHHHCCCCCCEEE
IALIPLGGYVKMLDERVDSVAPELRHQAFNNKTVWQRAAIISAGPIANFLFAILAYWLVF
EEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHH
IIGVPSFRPVIGEIAPQSIAAHAEISPGMELKSVDGIETPDWESVRLALVAKIGDAETEV
HHCCCCCHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCC
GIAPFGSSSVVTKTLDLRQWNFEPDKQDPVVALGIIPRGPQIESVLAEVQPGSAAQKAGL
CCCCCCCCCCEEEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHHHHHCCCCCHHHHCCC
QAGDRIVKVDGQLLGRWQTLVKRIHNGPGQPLALEIERNGAPLSLTLIPDTKPVGKDKSV
CCCCEEEEECHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEECCCCCCCCCCCCC
GFAGIIPKVLPLPDEYKTIRQYGPFPALYQAGDKTWQLMSLTVKMLGKLITGDVKLNNLS
CHHHHCHHHCCCCHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCEEEECCC
GPISIAQGAGASAGVGFVYYLMFLALISVNLGIINLFPLPVLDGGHLLFLAIEKLKGGPV
CCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCEECCCCEEEEEEEHHCCCCH
SERVQDYSYRIGSIVLVLLMGLALFNDFSRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]