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The map label for this gene is menC [H]

Identifier: 157371517

GI number: 157371517

Start: 3623381

End: 3624364

Strand: Reverse

Name: menC [H]

Synonym: Spro_3280

Alternate gene names: 157371517

Gene position: 3624364-3623381 (Counterclockwise)

Preceding gene: 157371518

Following gene: 157371516

Centisome position: 66.52

GC content: 60.57

Gene sequence:

>984_bases
ATGAACACAACCCCCCGTAACGCGGCCCTTTACCGTTACAGCCTGCCAATGGACGCGGGCGTTGTGTTGCGCAATCAGCG
GCTAAAAACCCGCGATGGTTTGCTGATCCACCTGCAGCAGGGTGAGCAAGAAGGCTGGGGAGAGATTGCGCCGTTGCCTG
AATTCAGCCAGGAAACGCTGGCGCAGGCTGAACAGGCCGCGCTGAACTGGCTGCAGAGCTGGCAAAGTGGGGTATTACCA
CCCGAAAGCCCGTTACCCTCGGTGGCGTTCGGCACCAGTTGCGCGGTGGCGGAGCTGGAACAGCGGCTGCCGCAGCAGGC
TGATTACCGTAAAGCGCCGTTGTGCACCGGCGACCCTGATGAGCTGTTCGAGGTATTGACTGCTTTGCCAGGTGAGAAGG
TCGCCAAGGTAAAGGTTGGGCTGTATGAAGCGGTGCGTGACGGCATGGTTGTCAACGTGCTGCTGGAGGCACTGCCGGAT
CTCAGGCTGCGGCTGGACGCTAACCGCAGTTGGACACGCGCCAAAGCGGATGGGTTTGCCAAATACGTCAATCCGGCTGT
GCGCGATCGCATTGCTTTCCTTGAAGAGCCTTGCAAAACCCGCGATGAATCACGGGATTTCGCTCAGGCGACCGGCATTG
CCATTGCCTGGGACGAAAGCGTGCGCGAGGCGGATTTTGTGGTGCAGGCGGAGCCGGGCGTGGCAGCGATAGTGATTAAG
CCGACGCTGGTCGGCAGCCTGGCCCGTTGCCGTTCGTTGGTGGAGCAGGCCCATGCGGTGGGATTAACGGCGGTGATCAG
TTCCAGCATTGAGTCCAGCCTGGGATTGACACAGTTGGCGCGCATCGCGCACTGGCTGACGCCGACGACCGTCCCTGGGC
TAGACACGCTGGATTTGATGCAGGCGCAATTACTGCGACGCTGGCCGGATAGCCGGCTGCCGTTATTGGAGACGCAAGAG
TTGGAGTGTTTATGGCGCAGTTGA

Upstream 100 bases:

>100_bases
CCACCATGCTGTTCTACATGACTGACGAAGGCCAGGAAGGACGCAACGCGTTTAACGAAAAGCGCCAGCCGGACTTCAGC
AAATTCAAGCGTAACCCGTA

Downstream 100 bases:

>100_bases
ATGACTGGCCGTGGCGACATTGGGCGCAGCGGCGTCCGCAGGCGGCGGCGCTGGTTGTCGGCCATCAGCCGGTGAGTTGG
CTGGTGTTACGCCGTCAGGT

Product: O-succinylbenzoate synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNTTPRNAALYRYSLPMDAGVVLRNQRLKTRDGLLIHLQQGEQEGWGEIAPLPEFSQETLAQAEQAALNWLQSWQSGVLP
PESPLPSVAFGTSCAVAELEQRLPQQADYRKAPLCTGDPDELFEVLTALPGEKVAKVKVGLYEAVRDGMVVNVLLEALPD
LRLRLDANRSWTRAKADGFAKYVNPAVRDRIAFLEEPCKTRDESRDFAQATGIAIAWDESVREADFVVQAEPGVAAIVIK
PTLVGSLARCRSLVEQAHAVGLTAVISSSIESSLGLTQLARIAHWLTPTTVPGLDTLDLMQAQLLRRWPDSRLPLLETQE
LECLWRS

Sequences:

>Translated_327_residues
MNTTPRNAALYRYSLPMDAGVVLRNQRLKTRDGLLIHLQQGEQEGWGEIAPLPEFSQETLAQAEQAALNWLQSWQSGVLP
PESPLPSVAFGTSCAVAELEQRLPQQADYRKAPLCTGDPDELFEVLTALPGEKVAKVKVGLYEAVRDGMVVNVLLEALPD
LRLRLDANRSWTRAKADGFAKYVNPAVRDRIAFLEEPCKTRDESRDFAQATGIAIAWDESVREADFVVQAEPGVAAIVIK
PTLVGSLARCRSLVEQAHAVGLTAVISSSIESSLGLTQLARIAHWLTPTTVPGLDTLDLMQAQLLRRWPDSRLPLLETQE
LECLWRS
>Mature_327_residues
MNTTPRNAALYRYSLPMDAGVVLRNQRLKTRDGLLIHLQQGEQEGWGEIAPLPEFSQETLAQAEQAALNWLQSWQSGVLP
PESPLPSVAFGTSCAVAELEQRLPQQADYRKAPLCTGDPDELFEVLTALPGEKVAKVKVGLYEAVRDGMVVNVLLEALPD
LRLRLDANRSWTRAKADGFAKYVNPAVRDRIAFLEEPCKTRDESRDFAQATGIAIAWDESVREADFVVQAEPGVAAIVIK
PTLVGSLARCRSLVEQAHAVGLTAVISSSIESSLGLTQLARIAHWLTPTTVPGLDTLDLMQAQLLRRWPDSRLPLLETQE
LECLWRS

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=320, Percent_Identity=69.6875, Blast_Score=440, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 36070; Mature: 36070

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTPRNAALYRYSLPMDAGVVLRNQRLKTRDGLLIHLQQGEQEGWGEIAPLPEFSQETL
CCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
AQAEQAALNWLQSWQSGVLPPESPLPSVAFGTSCAVAELEQRLPQQADYRKAPLCTGDPD
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHH
ELFEVLTALPGEKVAKVKVGLYEAVRDGMVVNVLLEALPDLRLRLDANRSWTRAKADGFA
HHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHH
KYVNPAVRDRIAFLEEPCKTRDESRDFAQATGIAIAWDESVREADFVVQAEPGVAAIVIK
HHHCHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCCCCCEEEEECCCEEEEEEC
PTLVGSLARCRSLVEQAHAVGLTAVISSSIESSLGLTQLARIAHWLTPTTVPGLDTLDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHH
QAQLLRRWPDSRLPLLETQELECLWRS
HHHHHHHCCCCCCCCCCCCHHHHHCCC
>Mature Secondary Structure
MNTTPRNAALYRYSLPMDAGVVLRNQRLKTRDGLLIHLQQGEQEGWGEIAPLPEFSQETL
CCCCCCCCEEEEEECCCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHH
AQAEQAALNWLQSWQSGVLPPESPLPSVAFGTSCAVAELEQRLPQQADYRKAPLCTGDPD
HHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHH
ELFEVLTALPGEKVAKVKVGLYEAVRDGMVVNVLLEALPDLRLRLDANRSWTRAKADGFA
HHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHH
KYVNPAVRDRIAFLEEPCKTRDESRDFAQATGIAIAWDESVREADFVVQAEPGVAAIVIK
HHHCHHHHHHHHHHHHHHHCCHHHHHHHHHCCEEEEECCCCCCCCEEEEECCCEEEEEEC
PTLVGSLARCRSLVEQAHAVGLTAVISSSIESSLGLTQLARIAHWLTPTTVPGLDTLDLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHH
QAQLLRRWPDSRLPLLETQELECLWRS
HHHHHHHCCCCCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA