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The map label for this gene is argF [H]

Identifier: 157371427

GI number: 157371427

Start: 3510958

End: 3511896

Strand: Reverse

Name: argF [H]

Synonym: Spro_3190

Alternate gene names: 157371427

Gene position: 3511896-3510958 (Counterclockwise)

Preceding gene: 157371428

Following gene: 157371426

Centisome position: 64.45

GC content: 50.48

Gene sequence:

>939_bases
ATGAGAGATAAATTTCGCGCCAGACACTATCTTGCCATGCAGGATTATACAGCGGAAGAGATCCGTTATTTGGTCGAGCT
GGCAACCGATTTAAAACGCAAATGGACCATGCGTGAGCCACATGAATATTTACGTGGGCGTACCTATGGCATGATTTTCG
AAAAAAAATCTACGCGTACCCGTAATTCCTTCCATGCCGCCGCAACGGCGCTGGGGGCTCAGTCTATCTATCTGCGACCG
GATGAAATGCAACTCAGCCGTGGCGAGCCAATTAAAGATACCGCACGCATTATTGATCGCTATTTTGATGGTTTGTATAT
CCGAACTTATGGACAGGAAATTGTTCAGGAGTTTGCGCAATACATGAAAAATCCGGTGATTAACGCGTTAACGGCGCTGG
AACATCCTTGCCAGGGGCTGGCCGACCTTCTGACCATTAAAGAAAAATTTGGTGAATGGAAAGGGGTAAAAGTCTGTTAT
GCCGGCGATGTCTATAACGTCTGTCATTCCCTGATGATCGGCTGCGGCATGATGGGAATGGATATTTACGTTGCTGCCCC
TGAAGGATACGAACCCGTACCGGAAATTCTGGCCTGTGCGCAGCAACACGCGGCGAAAAGCGGTTCCAAAGTCATCGTGA
CCCGGGATTTCGACGAGGCGCTGCGTGGAGCTGATGTGGTATATGGCAACACCTGGCATAGCATGGGTGAAAACGAAGCC
CAGAAAGAAAAGCGCATTCAAGACTTTATGCCGTACCAGATCAACGCCCAGGTAATGGCGAAAGCGCGTAAAACGGCGGT
CTTCATGCATTGCCTGCCGGGTTACCGTGGCGAAGATATGACAGACGAAGTCATTGAAGGGCCACAGTCCGTGGTGTGGG
ATCAGGGTGAAAACCGCATGCACACCGTGAAGGCCGTTATGGTGGCTACGGCGGTCTAG

Upstream 100 bases:

>100_bases
TTACGCTCAGTGGCACATCAGTAAATATTCAGATGGGTACAGTGGCTGGAATGCTGCTATCCGTAAAATGGGCGTTTTAC
CAAACATCGAGGGATATGAA

Downstream 100 bases:

>100_bases
CATTCCGGCTCAAAGGCGAGGGAGCCAAAATTCTGGCTCCTCCGCGTAATGCCGTCAGATATCACTTCTACTTTTAGTCG
CCATCCGTACTTCACTAAGG

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRDKFRARHYLAMQDYTAEEIRYLVELATDLKRKWTMREPHEYLRGRTYGMIFEKKSTRTRNSFHAAATALGAQSIYLRP
DEMQLSRGEPIKDTARIIDRYFDGLYIRTYGQEIVQEFAQYMKNPVINALTALEHPCQGLADLLTIKEKFGEWKGVKVCY
AGDVYNVCHSLMIGCGMMGMDIYVAAPEGYEPVPEILACAQQHAAKSGSKVIVTRDFDEALRGADVVYGNTWHSMGENEA
QKEKRIQDFMPYQINAQVMAKARKTAVFMHCLPGYRGEDMTDEVIEGPQSVVWDQGENRMHTVKAVMVATAV

Sequences:

>Translated_312_residues
MRDKFRARHYLAMQDYTAEEIRYLVELATDLKRKWTMREPHEYLRGRTYGMIFEKKSTRTRNSFHAAATALGAQSIYLRP
DEMQLSRGEPIKDTARIIDRYFDGLYIRTYGQEIVQEFAQYMKNPVINALTALEHPCQGLADLLTIKEKFGEWKGVKVCY
AGDVYNVCHSLMIGCGMMGMDIYVAAPEGYEPVPEILACAQQHAAKSGSKVIVTRDFDEALRGADVVYGNTWHSMGENEA
QKEKRIQDFMPYQINAQVMAKARKTAVFMHCLPGYRGEDMTDEVIEGPQSVVWDQGENRMHTVKAVMVATAV
>Mature_312_residues
MRDKFRARHYLAMQDYTAEEIRYLVELATDLKRKWTMREPHEYLRGRTYGMIFEKKSTRTRNSFHAAATALGAQSIYLRP
DEMQLSRGEPIKDTARIIDRYFDGLYIRTYGQEIVQEFAQYMKNPVINALTALEHPCQGLADLLTIKEKFGEWKGVKVCY
AGDVYNVCHSLMIGCGMMGMDIYVAAPEGYEPVPEILACAQQHAAKSGSKVIVTRDFDEALRGADVVYGNTWHSMGENEA
QKEKRIQDFMPYQINAQVMAKARKTAVFMHCLPGYRGEDMTDEVIEGPQSVVWDQGENRMHTVKAVMVATAV

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=309, Percent_Identity=37.5404530744337, Blast_Score=225, Evalue=3e-59,
Organism=Homo sapiens, GI18105007, Length=313, Percent_Identity=26.1980830670927, Blast_Score=108, Evalue=8e-24,
Organism=Escherichia coli, GI1786469, Length=332, Percent_Identity=38.5542168674699, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI1790703, Length=328, Percent_Identity=38.109756097561, Blast_Score=223, Evalue=1e-59,
Organism=Escherichia coli, GI48994908, Length=315, Percent_Identity=24.4444444444444, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367364, Length=197, Percent_Identity=28.4263959390863, Blast_Score=67, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI193204318, Length=312, Percent_Identity=24.3589743589744, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6322373, Length=309, Percent_Identity=32.0388349514563, Blast_Score=179, Evalue=6e-46,
Organism=Saccharomyces cerevisiae, GI6322331, Length=290, Percent_Identity=27.2413793103448, Blast_Score=100, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24642586, Length=309, Percent_Identity=26.2135922330097, Blast_Score=112, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 35593; Mature: 35593

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDKFRARHYLAMQDYTAEEIRYLVELATDLKRKWTMREPHEYLRGRTYGMIFEKKSTRT
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEECCCCCC
RNSFHAAATALGAQSIYLRPDEMQLSRGEPIKDTARIIDRYFDGLYIRTYGQEIVQEFAQ
HHHHHHHHHHHCCCEEEECCCHHHCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHH
YMKNPVINALTALEHPCQGLADLLTIKEKFGEWKGVKVCYAGDVYNVCHSLMIGCGMMGM
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCC
DIYVAAPEGYEPVPEILACAQQHAAKSGSKVIVTRDFDEALRGADVVYGNTWHSMGENEA
EEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCCEEECCCHHHCCCCHH
QKEKRIQDFMPYQINAQVMAKARKTAVFMHCLPGYRGEDMTDEVIEGPQSVVWDQGENRM
HHHHHHHHCCCCEECHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHCCCCCCHH
HTVKAVMVATAV
HHHHHHHHHHCC
>Mature Secondary Structure
MRDKFRARHYLAMQDYTAEEIRYLVELATDLKRKWTMREPHEYLRGRTYGMIFEKKSTRT
CCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCEEEEEECCCCCC
RNSFHAAATALGAQSIYLRPDEMQLSRGEPIKDTARIIDRYFDGLYIRTYGQEIVQEFAQ
HHHHHHHHHHHCCCEEEECCCHHHCCCCCCHHHHHHHHHHHHCCEEEEHHHHHHHHHHHH
YMKNPVINALTALEHPCQGLADLLTIKEKFGEWKGVKVCYAGDVYNVCHSLMIGCGMMGM
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCCC
DIYVAAPEGYEPVPEILACAQQHAAKSGSKVIVTRDFDEALRGADVVYGNTWHSMGENEA
EEEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHHCCCCEEECCCHHHCCCCHH
QKEKRIQDFMPYQINAQVMAKARKTAVFMHCLPGYRGEDMTDEVIEGPQSVVWDQGENRM
HHHHHHHHCCCCEECHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHCCCCCCHH
HTVKAVMVATAV
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA