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The map label for this gene is fur [H]

Identifier: 157369479

GI number: 157369479

Start: 1361468

End: 1361914

Strand: Reverse

Name: fur [H]

Synonym: Spro_1236

Alternate gene names: 157369479

Gene position: 1361914-1361468 (Counterclockwise)

Preceding gene: 157369480

Following gene: 157369470

Centisome position: 24.99

GC content: 49.89

Gene sequence:

>447_bases
ATGACTGACAACAACACCGCATTGAAGAAGGCCGGCTTAAAAGTCACGCTTCCGCGACTCAAAATCCTGGAAGTACTGCA
AAATCCGGAATGCCATCACGTCAGTGCGGAAGATCTGTACAAAAAACTGATAGATATGGGCGAAGAAATTGGCCTGGCTA
CGGTTTACCGCGTACTGAACCAATTTGATGATGCCGGCATTGTGACCCGTCACAATTTCGAAGGCGGCAAGTCCGTATTC
GAACTGACCCAGCAGCATCACCACGATCACCTGATTTGCCTGGACTGCGGCAAAGTGATCGAATTCAGCGATGAATCTAT
CGAAGTTCGTCAGCGTGATATCGCCAAGCAGCACGGCATCAAGCTCAGCAACCACAGCCTGTACCTGTATGGCCACTGTG
AAGCCGGTGACTGCCGCGAAGACGAAACTCTGCACGATAAAAAATAA

Upstream 100 bases:

>100_bases
AACCGGTTCTATAATGAGACGCAATTAACTCTTTGTGCCGACCGATGCCACAGGCGAGAACGCCTCAACTTGATTAGCAT
AGTAACAGGACTGAATCCGC

Downstream 100 bases:

>100_bases
TGCCCTCAACCGGCATTGAGAACCGCCTTCATGGCGGTTTTTTTATGCCCATAGCCCGGTAACGAACAGATAAAAAAATC
CCCGGACAGGTCCGGGGAAA

Product: ferric uptake regulator

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MTDNNTALKKAGLKVTLPRLKILEVLQNPECHHVSAEDLYKKLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVF
ELTQQHHHDHLICLDCGKVIEFSDESIEVRQRDIAKQHGIKLSNHSLYLYGHCEAGDCREDETLHDKK

Sequences:

>Translated_148_residues
MTDNNTALKKAGLKVTLPRLKILEVLQNPECHHVSAEDLYKKLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVF
ELTQQHHHDHLICLDCGKVIEFSDESIEVRQRDIAKQHGIKLSNHSLYLYGHCEAGDCREDETLHDKK
>Mature_147_residues
TDNNTALKKAGLKVTLPRLKILEVLQNPECHHVSAEDLYKKLIDMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFE
LTQQHHHDHLICLDCGKVIEFSDESIEVRQRDIAKQHGIKLSNHSLYLYGHCEAGDCREDETLHDKK

Specific function: Fur acts as a repressor, employing Fe(2+) as a cofactor to bind the operator of the iron transport operon [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

Organism=Escherichia coli, GI1786899, Length=148, Percent_Identity=88.5135135135135, Blast_Score=273, Evalue=5e-75,

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 16861; Mature: 16730

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNNTALKKAGLKVTLPRLKILEVLQNPECHHVSAEDLYKKLIDMGEEIGLATVYRVLN
CCCCCCHHHHCCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHH
QFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDESIEVRQRDIAKQHGI
HCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHCC
KLSNHSLYLYGHCEAGDCREDETLHDKK
EECCCEEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDNNTALKKAGLKVTLPRLKILEVLQNPECHHVSAEDLYKKLIDMGEEIGLATVYRVLN
CCCCCHHHHCCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCHHCCHHHHHHHHH
QFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEFSDESIEVRQRDIAKQHGI
HCCCCCCEEECCCCCCHHHHHHHHHHCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHCC
KLSNHSLYLYGHCEAGDCREDETLHDKK
EECCCEEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406286; 11586360; 12142430 [H]