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The map label for this gene is fldA [H]

Identifier: 157369480

GI number: 157369480

Start: 1362235

End: 1362774

Strand: Reverse

Name: fldA [H]

Synonym: Spro_1237

Alternate gene names: 157369480

Gene position: 1362774-1362235 (Counterclockwise)

Preceding gene: 157369481

Following gene: 157369479

Centisome position: 25.01

GC content: 50.74

Gene sequence:

>540_bases
ATGGCTAATGTAGGCATTTTCTTTGGCAGCGACACTGGCAATACCGAAAACATTGCCAAGATGATCCAGAAAATTCTTAA
GCAACAGTTCGGTGACGATGTGTGCGAAATTCACGACATCGCCAAAAGCAGCAAAGAAGACCTGGAAGGCTTCGACATTT
TGTTGCTCGGTATTCCAACCTGGTACTACGGTGAAGCCCAGTGTGACTGGGATGACTTCTTCCCAACGCTGGAAGACATC
GACTTCAACGGCAAGCTGGTAGCCCTGTTTGGCTGCGGCGATCAGGAAGACTACGCAGAATATTTCTGTGATGCGATGGG
CACCATCCGCGACATCATTGAACCGCGTGGCGCTGCCATCGTCGGCCACTGGCCAACCAAAGGCTATCATTTCGAAGCCT
CGAAAGGTTTGGCAAGCGACAGCCACTTCATTGGCCTGGCGATTGACGAAGACCGTCAACCTGAACTAACCAATGAGCGT
GTTGAAGGTTGGGTAAAACAAATCGTCGAAGAGCTGAGCCTGGCCGAAATTGTCGGCTAA

Upstream 100 bases:

>100_bases
TGAGGGCTCCCCTTGCCATGGCATCATTTTAATCGGTGTTATCGTGGTCAGCGCTAACATCGTGTAATGCAATTTATTGA
ATTTAAAGGTTATACGCGAT

Downstream 100 bases:

>100_bases
CGCCAAAGGTTGAACAAAAGCCCTGCAAAGTGCATAGTGTTGCCGGCAGGGCCATCATTGGCAGTACTGATTACTGCAAT
CGAAGATACATATTTGTAAC

Product: flavodoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 178

Protein sequence:

>179_residues
MANVGIFFGSDTGNTENIAKMIQKILKQQFGDDVCEIHDIAKSSKEDLEGFDILLLGIPTWYYGEAQCDWDDFFPTLEDI
DFNGKLVALFGCGDQEDYAEYFCDAMGTIRDIIEPRGAAIVGHWPTKGYHFEASKGLASDSHFIGLAIDEDRQPELTNER
VEGWVKQIVEELSLAEIVG

Sequences:

>Translated_179_residues
MANVGIFFGSDTGNTENIAKMIQKILKQQFGDDVCEIHDIAKSSKEDLEGFDILLLGIPTWYYGEAQCDWDDFFPTLEDI
DFNGKLVALFGCGDQEDYAEYFCDAMGTIRDIIEPRGAAIVGHWPTKGYHFEASKGLASDSHFIGLAIDEDRQPELTNER
VEGWVKQIVEELSLAEIVG
>Mature_178_residues
ANVGIFFGSDTGNTENIAKMIQKILKQQFGDDVCEIHDIAKSSKEDLEGFDILLLGIPTWYYGEAQCDWDDFFPTLEDID
FNGKLVALFGCGDQEDYAEYFCDAMGTIRDIIEPRGAAIVGHWPTKGYHFEASKGLASDSHFIGLAIDEDRQPELTNERV
EGWVKQIVEELSLAEIVG

Specific function: Low-potential electron donor to a number of redox enzymes (Potential). Involved in the reactivation of inactive cob(II)alamin in methionine synthase [H]

COG id: COG0716

COG function: function code C; Flavodoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Escherichia coli, GI1786900, Length=178, Percent_Identity=85.3932584269663, Blast_Score=312, Evalue=6e-87,
Organism=Escherichia coli, GI1789262, Length=172, Percent_Identity=41.2790697674419, Blast_Score=152, Evalue=2e-38,

Paralogues:

None

Copy number: 242 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008254
- InterPro:   IPR001226
- InterPro:   IPR010086 [H]

Pfam domain/function: PF00258 Flavodoxin_1 [H]

EC number: NA

Molecular weight: Translated: 20007; Mature: 19875

Theoretical pI: Translated: 3.99; Mature: 3.99

Prosite motif: PS00201 FLAVODOXIN ; PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVGIFFGSDTGNTENIAKMIQKILKQQFGDDVCEIHDIAKSSKEDLEGFDILLLGIPT
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCCCCEEEEEECCC
WYYGEAQCDWDDFFPTLEDIDFNGKLVALFGCGDQEDYAEYFCDAMGTIRDIIEPRGAAI
EECCCCCCCHHHHCCCHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEE
VGHWPTKGYHFEASKGLASDSHFIGLAIDEDRQPELTNERVEGWVKQIVEELSLAEIVG
EECCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ANVGIFFGSDTGNTENIAKMIQKILKQQFGDDVCEIHDIAKSSKEDLEGFDILLLGIPT
CCEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCHHHCCCCEEEEEECCC
WYYGEAQCDWDDFFPTLEDIDFNGKLVALFGCGDQEDYAEYFCDAMGTIRDIIEPRGAAI
EECCCCCCCHHHHCCCHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCEE
VGHWPTKGYHFEASKGLASDSHFIGLAIDEDRQPELTNERVEGWVKQIVEELSLAEIVG
EECCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FMN. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]