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The map label for this gene is nagC [H]

Identifier: 157369468

GI number: 157369468

Start: 1344550

End: 1345770

Strand: Reverse

Name: nagC [H]

Synonym: Spro_1225

Alternate gene names: 157369468

Gene position: 1345770-1344550 (Counterclockwise)

Preceding gene: 157369469

Following gene: 157369467

Centisome position: 24.7

GC content: 58.15

Gene sequence:

>1221_bases
ATGAGTACTGGCGGACAGGCACAGATAGGGAACGTTGACTTAGTCAAGCAACTCAACGGCGCAGCGGTTTACCGCCTGAT
CGACCAACAGGGTCCGATTTCGCGCATTCAAATAGCCGAACTGAGCCAGCTAGCGCCCGCCAGCGTCACTAAAATTACTC
GCCAGCTGTTGGAGCGCGGGCTGATCAAAGAAGTCGATCAGCAAGCCTCCACCGGCGGTCGCCGCGCCATTTCCATTGTC
TCCGAAACCCGGCATTTCCACACCGTGGCCGTGCGCCTCGGTCGTCACGACGCTACCATCACCCTGTACGATATGAGCGG
CAAGTCGCTCGGTGAAGAACACTACCCGTTGCCGGAACGCACCCAGGAGACACTGGAAAACGCGCTGTTTATCGCCATTG
CCCAGTTTATCGAAAACTACCAGCGCAAGCTGCGTGAGCTGATCGCCATCGCGGTGATCTTGCCAGGCCTGGTTGACCCG
GCGCTGGGCGTAGTGCGTTATATGCCGCATATCAGCGTCAACAACTGGGCGCTGGTAGACAACCTGCAGCAACGTTTTAA
CGTCACCAGCTTTGTTGGCCACGACATCCGCAGCCTGGCGTTGGCAGAGCATTACTTTGGTGCCACCCGCGACTGCGAAG
ACTCTATTCTGGTGCGCCTGCACCGTGGCACCGGTGCCGGTATTATCGTCAACGGCCAGATTTTCCTGGGCAACAACGGC
AACGTCGGTGAAATCGGCCATATTCAAATTGACCCATTGGGCGAACGCTGCCACTGCGGCAACTTCGGCTGTCTGGAAAC
CGTCGCCGCCAACGCCGCGATTGAACACCGTGTACGCCAGTTGCTGACCCAGGGCTACCCCAGCAAGCTAACCCTCGACG
ACTGTAGCATCTCCGCCATCTGCAAGGCCGCCAACCGCGGCGACCTGCTGGCCAGCGAAGTGATCGAGCACGTCGGCCGC
TACCTCGGCAAAGCCGTGGCGATCGCCATCAACCTGTTCAATCCACAGAAAGTAGTGATCGCCGGTGAAATTACCGAGGC
GGAAAAAGTGTTGTTGCCGGCGATCCAAAGCTGCATCAATACTCAGGTGCTGAAGGACTTCCGCAAAAATCTGCCGGTGG
TCACCTCCGAACTCAATCATCGCTCGGCGATCGGCGCTTTCGCCCTGGCCAAACGAGCGATGCTCAACGGCGTGCTATTG
CAGCGATTGCTGGAAAGCTGA

Upstream 100 bases:

>100_bases
AGTGGCGAACCTGACTGCCTTTACCCGTGATTTTAAAATCACCAAAACGCTCGTTAACGGTAACGAGGTTTAATTTAATG
AACAGCGAGTAAAATTATTG

Downstream 100 bases:

>100_bases
TCCGCCGCTTCAGGCAGGTGTGCTATCTTCGCGTTTTGCCTGCCGCAAATCATGAGAAACAGCAACAATGACAATCAAAA
ACGTTATATGTGATATCGAC

Product: ROK family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSTGGQAQIGNVDLVKQLNGAAVYRLIDQQGPISRIQIAELSQLAPASVTKITRQLLERGLIKEVDQQASTGGRRAISIV
SETRHFHTVAVRLGRHDATITLYDMSGKSLGEEHYPLPERTQETLENALFIAIAQFIENYQRKLRELIAIAVILPGLVDP
ALGVVRYMPHISVNNWALVDNLQQRFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAGIIVNGQIFLGNNG
NVGEIGHIQIDPLGERCHCGNFGCLETVAANAAIEHRVRQLLTQGYPSKLTLDDCSISAICKAANRGDLLASEVIEHVGR
YLGKAVAIAINLFNPQKVVIAGEITEAEKVLLPAIQSCINTQVLKDFRKNLPVVTSELNHRSAIGAFALAKRAMLNGVLL
QRLLES

Sequences:

>Translated_406_residues
MSTGGQAQIGNVDLVKQLNGAAVYRLIDQQGPISRIQIAELSQLAPASVTKITRQLLERGLIKEVDQQASTGGRRAISIV
SETRHFHTVAVRLGRHDATITLYDMSGKSLGEEHYPLPERTQETLENALFIAIAQFIENYQRKLRELIAIAVILPGLVDP
ALGVVRYMPHISVNNWALVDNLQQRFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAGIIVNGQIFLGNNG
NVGEIGHIQIDPLGERCHCGNFGCLETVAANAAIEHRVRQLLTQGYPSKLTLDDCSISAICKAANRGDLLASEVIEHVGR
YLGKAVAIAINLFNPQKVVIAGEITEAEKVLLPAIQSCINTQVLKDFRKNLPVVTSELNHRSAIGAFALAKRAMLNGVLL
QRLLES
>Mature_405_residues
STGGQAQIGNVDLVKQLNGAAVYRLIDQQGPISRIQIAELSQLAPASVTKITRQLLERGLIKEVDQQASTGGRRAISIVS
ETRHFHTVAVRLGRHDATITLYDMSGKSLGEEHYPLPERTQETLENALFIAIAQFIENYQRKLRELIAIAVILPGLVDPA
LGVVRYMPHISVNNWALVDNLQQRFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAGIIVNGQIFLGNNGN
VGEIGHIQIDPLGERCHCGNFGCLETVAANAAIEHRVRQLLTQGYPSKLTLDDCSISAICKAANRGDLLASEVIEHVGRY
LGKAVAIAINLFNPQKVVIAGEITEAEKVLLPAIQSCINTQVLKDFRKNLPVVTSELNHRSAIGAFALAKRAMLNGVLLQ
RLLES

Specific function: Acts as a repressor of the nagEBACD operon and acts both as an activator and a repressor for the transcription of the glmSU operon [H]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1786891, Length=406, Percent_Identity=81.2807881773399, Blast_Score=686, Evalue=0.0,
Organism=Escherichia coli, GI1787878, Length=400, Percent_Identity=39.5, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI87082127, Length=344, Percent_Identity=22.3837209302326, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081733, Length=272, Percent_Identity=22.7941176470588, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790522, Length=325, Percent_Identity=23.3846153846154, Blast_Score=69, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000835
- InterPro:   IPR000600
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR; PF00480 ROK [H]

EC number: NA

Molecular weight: Translated: 44317; Mature: 44186

Theoretical pI: Translated: 7.87; Mature: 7.87

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTGGQAQIGNVDLVKQLNGAAVYRLIDQQGPISRIQIAELSQLAPASVTKITRQLLERG
CCCCCCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCEEHHHHHHCCCHHHHHHHHHHHHHH
LIKEVDQQASTGGRRAISIVSETRHFHTVAVRLGRHDATITLYDMSGKSLGEEHYPLPER
HHHHHHHHHCCCCHHEEHHHHHHHHHEEEHEEECCCCCEEEEEECCCCCCCCCCCCCCHH
TQETLENALFIAIAQFIENYQRKLRELIAIAVILPGLVDPALGVVRYMPHISVNNWALVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
NLQQRFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAGIIVNGQIFLGNNG
HHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECCCC
NVGEIGHIQIDPLGERCHCGNFGCLETVAANAAIEHRVRQLLTQGYPSKLTLDDCSISAI
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHH
CKAANRGDLLASEVIEHVGRYLGKAVAIAINLFNPQKVVIAGEITEAEKVLLPAIQSCIN
HHHCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHH
TQVLKDFRKNLPVVTSELNHRSAIGAFALAKRAMLNGVLLQRLLES
HHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STGGQAQIGNVDLVKQLNGAAVYRLIDQQGPISRIQIAELSQLAPASVTKITRQLLERG
CCCCCCCCCCHHHHHHCCCHHHHHHHHCCCCCCCEEHHHHHHCCCHHHHHHHHHHHHHH
LIKEVDQQASTGGRRAISIVSETRHFHTVAVRLGRHDATITLYDMSGKSLGEEHYPLPER
HHHHHHHHHCCCCHHEEHHHHHHHHHEEEHEEECCCCCEEEEEECCCCCCCCCCCCCCHH
TQETLENALFIAIAQFIENYQRKLRELIAIAVILPGLVDPALGVVRYMPHISVNNWALVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHH
NLQQRFNVTSFVGHDIRSLALAEHYFGATRDCEDSILVRLHRGTGAGIIVNGQIFLGNNG
HHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECCCC
NVGEIGHIQIDPLGERCHCGNFGCLETVAANAAIEHRVRQLLTQGYPSKLTLDDCSISAI
CCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCHHHH
CKAANRGDLLASEVIEHVGRYLGKAVAIAINLFNPQKVVIAGEITEAEKVLLPAIQSCIN
HHHCCCCCHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHH
TQVLKDFRKNLPVVTSELNHRSAIGAFALAKRAMLNGVLLQRLLES
HHHHHHHHHCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]