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The map label for this gene is nagD [H]

Identifier: 157369467

GI number: 157369467

Start: 1343730

End: 1344482

Strand: Reverse

Name: nagD [H]

Synonym: Spro_1224

Alternate gene names: 157369467

Gene position: 1344482-1343730 (Counterclockwise)

Preceding gene: 157369468

Following gene: 157369466

Centisome position: 24.67

GC content: 56.18

Gene sequence:

>753_bases
ATGACAATCAAAAACGTTATATGTGATATCGACGGCGTGCTGCTGCATGACAACACGCCGGTACCCGGCGCCGATCTTTT
CCTCGCTCGCATTCAGGAACAGGGCATGCCGCTGGTAGTGCTGACCAACTATCCGTCACAGACAGCGCAGGATCTGGCGA
ACCGCTTCGCCGCCGCCGGACTGGAAGTGCCGGAAAGCGCGTTTTATACCTCCGCGATGGCCACCGCCGATTTCCTGCGC
CGCCAGGAAGGCAAAAAAGCCTATGTGGTCGGTGAAGGTGCGCTGATTCATGAACTGTATAAAGCCGGTTTCACTATTAC
CGACATCAACCCGGACTTCGTCATCGTCGGCGAAACCCGCTCCTACAACTGGGACATGATGCATAAGGCCGCCTACTTCG
TGAATAACGGCGCGCGCTTTATTGCTACCAACCCGGATACCCACGGCCATGGCTTTGTTCCGGCCTGCGGTGCGCTGTGC
GCCCCAATCGAGAAAATCACCGGCCGCAAACCATTTTACGTTGGCAAACCAAGCCCGTGGATTATCCGCGCCGCACTGAA
CAAAATGCAGGGGCATTCGGAAGAAACGGTGATCGTCGGTGATAACCTGCGCACCGATATCCTGGCGGGCTTCCAGGCCG
GTCTGGAAACCGTCTTGGTGCTGTCCGGCGTCTCAACGCTGAACGATGTCGAAACCATGCCGTTCCGCCCGAGTTATATC
TTCCCGTCCGTCGCTGATATCAATATTTTCTAA

Upstream 100 bases:

>100_bases
GGCGTGCTATTGCAGCGATTGCTGGAAAGCTGATCCGCCGCTTCAGGCAGGTGTGCTATCTTCGCGTTTTGCCTGCCGCA
AATCATGAGAAACAGCAACA

Downstream 100 bases:

>100_bases
TCCCTGCGGTGGCCATTACGGTCACCCTTTAATTTGACTAGCTTGAATTAAATTTATTATTGCCCACCAAAGGTTTCACC
CCGGCCTCGTTAAAAAGTCG

Product: UMP phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MTIKNVICDIDGVLLHDNTPVPGADLFLARIQEQGMPLVVLTNYPSQTAQDLANRFAAAGLEVPESAFYTSAMATADFLR
RQEGKKAYVVGEGALIHELYKAGFTITDINPDFVIVGETRSYNWDMMHKAAYFVNNGARFIATNPDTHGHGFVPACGALC
APIEKITGRKPFYVGKPSPWIIRAALNKMQGHSEETVIVGDNLRTDILAGFQAGLETVLVLSGVSTLNDVETMPFRPSYI
FPSVADINIF

Sequences:

>Translated_250_residues
MTIKNVICDIDGVLLHDNTPVPGADLFLARIQEQGMPLVVLTNYPSQTAQDLANRFAAAGLEVPESAFYTSAMATADFLR
RQEGKKAYVVGEGALIHELYKAGFTITDINPDFVIVGETRSYNWDMMHKAAYFVNNGARFIATNPDTHGHGFVPACGALC
APIEKITGRKPFYVGKPSPWIIRAALNKMQGHSEETVIVGDNLRTDILAGFQAGLETVLVLSGVSTLNDVETMPFRPSYI
FPSVADINIF
>Mature_249_residues
TIKNVICDIDGVLLHDNTPVPGADLFLARIQEQGMPLVVLTNYPSQTAQDLANRFAAAGLEVPESAFYTSAMATADFLRR
QEGKKAYVVGEGALIHELYKAGFTITDINPDFVIVGETRSYNWDMMHKAAYFVNNGARFIATNPDTHGHGFVPACGALCA
PIEKITGRKPFYVGKPSPWIIRAALNKMQGHSEETVIVGDNLRTDILAGFQAGLETVLVLSGVSTLNDVETMPFRPSYIF
PSVADINIF

Specific function: Unknown

COG id: COG0647

COG function: function code G; Predicted sugar phosphatases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI10092677, Length=273, Percent_Identity=28.5714285714286, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI108796653, Length=293, Percent_Identity=29.3515358361775, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI14149777, Length=251, Percent_Identity=25.4980079681275, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1786890, Length=249, Percent_Identity=85.5421686746988, Blast_Score=455, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17562458, Length=284, Percent_Identity=27.112676056338, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17560956, Length=284, Percent_Identity=27.112676056338, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17558880, Length=281, Percent_Identity=27.4021352313167, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193210059, Length=259, Percent_Identity=25.4826254826255, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71984613, Length=268, Percent_Identity=25.3731343283582, Blast_Score=68, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319965, Length=235, Percent_Identity=26.3829787234043, Blast_Score=76, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24666141, Length=253, Percent_Identity=28.4584980237154, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24656326, Length=257, Percent_Identity=28.0155642023346, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI22026920, Length=243, Percent_Identity=29.2181069958848, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24666137, Length=291, Percent_Identity=27.1477663230241, Blast_Score=84, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24656330, Length=274, Percent_Identity=25.9124087591241, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920940, Length=242, Percent_Identity=24.7933884297521, Blast_Score=78, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 27269; Mature: 27137

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKNVICDIDGVLLHDNTPVPGADLFLARIQEQGMPLVVLTNYPSQTAQDLANRFAAAG
CCHHHEEECCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCC
LEVPESAFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKAGFTITDINPDFVIVGETR
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCC
SYNWDMMHKAAYFVNNGARFIATNPDTHGHGFVPACGALCAPIEKITGRKPFYVGKPSPW
CCCHHHHHHEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCE
IIRAALNKMQGHSEETVIVGDNLRTDILAGFQAGLETVLVLSGVSTLNDVETMPFRPSYI
EHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCC
FPSVADINIF
CCCCEEEEEC
>Mature Secondary Structure 
TIKNVICDIDGVLLHDNTPVPGADLFLARIQEQGMPLVVLTNYPSQTAQDLANRFAAAG
CHHHEEECCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCC
LEVPESAFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKAGFTITDINPDFVIVGETR
CCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHCCCEEEECCCCEEEEECCC
SYNWDMMHKAAYFVNNGARFIATNPDTHGHGFVPACGALCAPIEKITGRKPFYVGKPSPW
CCCHHHHHHEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCE
IIRAALNKMQGHSEETVIVGDNLRTDILAGFQAGLETVLVLSGVSTLNDVETMPFRPSYI
EHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCC
FPSVADINIF
CCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]