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The map label for this gene is nagA [H]

Identifier: 157369469

GI number: 157369469

Start: 1345798

End: 1346937

Strand: Reverse

Name: nagA [H]

Synonym: Spro_1226

Alternate gene names: 157369469

Gene position: 1346937-1345798 (Counterclockwise)

Preceding gene: 157369470

Following gene: 157369468

Centisome position: 24.72

GC content: 55.35

Gene sequence:

>1140_bases
ATGTTCGCTTTAACCCACGGCCGTATTTATACCGGCCACGACGTACTTGACGACCACGCAGTTATTATCGCTGATGGGCT
GATTGAACGAGTTTGCCCGCTGGCTGAACTGCCGGCCGGCATTGAAACGCGCGATCTGGGTGGCGCTATCCTGGCCCCCG
GTTTGATCGACGTGCAGCTTAACGGCTGTGGCGGCGTGCAATTTAACGACTCGCTGGAGGCCATTTCGGAACAGACGCTG
GAGATCATGCAGCGTGCCAACGAAAAATCCGGCTGTACCAGTTATCTGCCGACGCTGATCACCAGCAGCGACGAATTTAT
GAAGCACAGCATTGAAGTGATGCGCGCTTATTTGAAGAAACATCCCAATCAGGCGCTTGGCCTGCATCTGGAAGGGCCGT
ACCTTAGCCCACTGAAGAAAGGCACCCATAATCCGGCGTTTATCCGCAAACCGACCAGCGAGATGATCGACTATCTGTGC
GCCAATGCCGATGTGATCACCAAGGTCACGCTGGCGCCGGAAATGGTGGAGCCGCACTTTATCAAGCAATTGACCGAAGC
AGGCATCGTGGTGTCCGCCGGTCACTCGAACGCCACCTACGATCAGGCCCGTATCGGTTTTGCCGCCGGTATCACCTTCG
CCACTCACCTGTATAACGCCATGCCGTATATCACCGGGCGTGAACCAGGGCTGATGGGCGCGATTTTCGACACGCCGGAG
GTCTATACCGGGATTATCGCCGACGGCCATCACGTGGCCTGGGCGAGTATCCGTAACGCCAAACGCATGAAAGGTGATAA
ATTGGTGCTGGTCACCGACGCCACCGCGCCGGCAGGTGCCGATATCGACCAATTTATTTTTGCCGGTAAAACAATATACT
ATCGTGATGGGCTGTGCGTGGACGAAAACGGCACCCTGAGCGGCTCAGCGCTGACCATGATTGACGCGTTAAAAAACAGC
GTTGAGCATGTCGGTATTGCATTGGACGAAGCACTGCGCATGGCAACGCTGTATCCGGCGCGCGCTATCGGCGTGGACCA
CCGTTTAGGCACTATCGAGCCCGGTAAAGTGGCGAACCTGACTGCCTTTACCCGTGATTTTAAAATCACCAAAACGCTCG
TTAACGGTAACGAGGTTTAA

Upstream 100 bases:

>100_bases
CGAGCCATCCACCATGGAACTGAAAGTCAAAACCGTTAAATATTTCCGCGAGTTAGAAGCGGAAAGCGTTAAGAGTCTTT
AATTCTTGCAGGGGGCTACG

Downstream 100 bases:

>100_bases
TTTAATGAACAGCGAGTAAAATTATTGATGAGTACTGGCGGACAGGCACAGATAGGGAACGTTGACTTAGTCAAGCAACT
CAACGGCGCAGCGGTTTACC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MFALTHGRIYTGHDVLDDHAVIIADGLIERVCPLAELPAGIETRDLGGAILAPGLIDVQLNGCGGVQFNDSLEAISEQTL
EIMQRANEKSGCTSYLPTLITSSDEFMKHSIEVMRAYLKKHPNQALGLHLEGPYLSPLKKGTHNPAFIRKPTSEMIDYLC
ANADVITKVTLAPEMVEPHFIKQLTEAGIVVSAGHSNATYDQARIGFAAGITFATHLYNAMPYITGREPGLMGAIFDTPE
VYTGIIADGHHVAWASIRNAKRMKGDKLVLVTDATAPAGADIDQFIFAGKTIYYRDGLCVDENGTLSGSALTMIDALKNS
VEHVGIALDEALRMATLYPARAIGVDHRLGTIEPGKVANLTAFTRDFKITKTLVNGNEV

Sequences:

>Translated_379_residues
MFALTHGRIYTGHDVLDDHAVIIADGLIERVCPLAELPAGIETRDLGGAILAPGLIDVQLNGCGGVQFNDSLEAISEQTL
EIMQRANEKSGCTSYLPTLITSSDEFMKHSIEVMRAYLKKHPNQALGLHLEGPYLSPLKKGTHNPAFIRKPTSEMIDYLC
ANADVITKVTLAPEMVEPHFIKQLTEAGIVVSAGHSNATYDQARIGFAAGITFATHLYNAMPYITGREPGLMGAIFDTPE
VYTGIIADGHHVAWASIRNAKRMKGDKLVLVTDATAPAGADIDQFIFAGKTIYYRDGLCVDENGTLSGSALTMIDALKNS
VEHVGIALDEALRMATLYPARAIGVDHRLGTIEPGKVANLTAFTRDFKITKTLVNGNEV
>Mature_379_residues
MFALTHGRIYTGHDVLDDHAVIIADGLIERVCPLAELPAGIETRDLGGAILAPGLIDVQLNGCGGVQFNDSLEAISEQTL
EIMQRANEKSGCTSYLPTLITSSDEFMKHSIEVMRAYLKKHPNQALGLHLEGPYLSPLKKGTHNPAFIRKPTSEMIDYLC
ANADVITKVTLAPEMVEPHFIKQLTEAGIVVSAGHSNATYDQARIGFAAGITFATHLYNAMPYITGREPGLMGAIFDTPE
VYTGIIADGHHVAWASIRNAKRMKGDKLVLVTDATAPAGADIDQFIFAGKTIYYRDGLCVDENGTLSGSALTMIDALKNS
VEHVGIALDEALRMATLYPARAIGVDHRLGTIEPGKVANLTAFTRDFKITKTLVNGNEV

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=380, Percent_Identity=32.8947368421053, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI224922791, Length=377, Percent_Identity=32.8912466843501, Blast_Score=160, Evalue=2e-39,
Organism=Escherichia coli, GI1786892, Length=379, Percent_Identity=76.5171503957784, Blast_Score=612, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI17553768, Length=356, Percent_Identity=31.7415730337079, Blast_Score=149, Evalue=2e-36,
Organism=Drosophila melanogaster, GI19920392, Length=388, Percent_Identity=32.2164948453608, Blast_Score=156, Evalue=2e-38,
Organism=Drosophila melanogaster, GI281361140, Length=401, Percent_Identity=31.4214463840399, Blast_Score=152, Evalue=4e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40887; Mature: 40887

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFALTHGRIYTGHDVLDDHAVIIADGLIERVCPLAELPAGIETRDLGGAILAPGLIDVQL
CEEEECCEEEECCCCCCCCEEEEEHHHHHHHCCHHHCCCCCCCCCCCCEEECCCEEEEEE
NGCGGVQFNDSLEAISEQTLEIMQRANEKSGCTSYLPTLITSSDEFMKHSIEVMRAYLKK
CCCCCCEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
HPNQALGLHLEGPYLSPLKKGTHNPAFIRKPTSEMIDYLCANADVITKVTLAPEMVEPHF
CCCCEEEEEECCCCCCHHHCCCCCCCEEECCHHHHHHHHHCCCCCEEEEECCHHHCCHHH
IKQLTEAGIVVSAGHSNATYDQARIGFAAGITFATHLYNAMPYITGREPGLMGAIFDTPE
HHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCH
VYTGIIADGHHVAWASIRNAKRMKGDKLVLVTDATAPAGADIDQFIFAGKTIYYRDGLCV
HHEEEEECCCEEEHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHCCCEEEEECCEEE
DENGTLSGSALTMIDALKNSVEHVGIALDEALRMATLYPARAIGVDHRLGTIEPGKVANL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCEE
TAFTRDFKITKTLVNGNEV
EHHHHCCEEEEEECCCCCC
>Mature Secondary Structure
MFALTHGRIYTGHDVLDDHAVIIADGLIERVCPLAELPAGIETRDLGGAILAPGLIDVQL
CEEEECCEEEECCCCCCCCEEEEEHHHHHHHCCHHHCCCCCCCCCCCCEEECCCEEEEEE
NGCGGVQFNDSLEAISEQTLEIMQRANEKSGCTSYLPTLITSSDEFMKHSIEVMRAYLKK
CCCCCCEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
HPNQALGLHLEGPYLSPLKKGTHNPAFIRKPTSEMIDYLCANADVITKVTLAPEMVEPHF
CCCCEEEEEECCCCCCHHHCCCCCCCEEECCHHHHHHHHHCCCCCEEEEECCHHHCCHHH
IKQLTEAGIVVSAGHSNATYDQARIGFAAGITFATHLYNAMPYITGREPGLMGAIFDTPE
HHHHHHCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCH
VYTGIIADGHHVAWASIRNAKRMKGDKLVLVTDATAPAGADIDQFIFAGKTIYYRDGLCV
HHEEEEECCCEEEHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHCCCEEEEECCEEE
DENGTLSGSALTMIDALKNSVEHVGIALDEALRMATLYPARAIGVDHRLGTIEPGKVANL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCEE
TAFTRDFKITKTLVNGNEV
EHHHHCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]