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The map label for this gene is qor [C]

Identifier: 157369416

GI number: 157369416

Start: 1290935

End: 1291918

Strand: Direct

Name: qor [C]

Synonym: Spro_1173

Alternate gene names: 157369416

Gene position: 1290935-1291918 (Clockwise)

Preceding gene: 157369415

Following gene: 157369417

Centisome position: 23.69

GC content: 49.39

Gene sequence:

>984_bases
ATGCGTATTGCTGTACACGAATCTCTGGGTCAGCCAGAACAGGTTATGAGTATTCAAGAGACCTCTCGTCCAACACTGAA
AGCTGGTGAGGTGTTGTTACAAATGGTTCTCTCACCTATCCACAATCATGATCTGATGCAAATATCTGGTACCTACGGCA
CCAAGCCAACGCTACCTGCCAGGGCAGGTACCGAAGCTCTCGGCCGCGTCCTTGAGGTTGGGGAAGGAGTGAAGGATCTG
CAAATTGGCCAGAGAGTTGCTGCATCGGGGGCATTTGGTACTTGGGCTGATGCTTTTGTGGCGCCTGCGGATCAACTACT
GCCTATTCCTGATGGCATCAGTGATGAATTGGCTGCCCAACTGCTGGTTATGCCAGCAAGTGCAACTGTAGTACTGGACG
ATTTAGGAGTAAAAAGCGGTCAATGGATGGTGCTGAGTGCAGCGGCAGGCGCCGTAGGTAAAAACTTGGCACTGTTGGCA
GCCTCCCGTCAGATACGTGTTATTGGCCTGGTCAATCGGGACTCTCAGGTTAAAGAACTTAGAGCTCTTGGTGTGGATTT
GGTAGAAAACACAGAAAAGGACGGTTGGCAGCAACGCATAAAAACTGCGTTGAACGGCGAGGCACTACTTTATGGTCTGG
ACTCAGTTGCAGGGGAACTCACCGGAGAGATGCTGAGTGTCATGAATGATAACGCCACGGTGGTCGTCTTCGGTGCATTG
AGCAACCACCCCCTGCGCATTGATTTTCAGGATGTCATTTTCAAGCAGGCTACAGTTCGCGGTTTCTGGGGGCTGAGGAA
ATTCGCTGCCTTGAACAACGAATATAAATTACGAATGATATCGGAGATTATGACAATGGCTTTACGGGATGGGTTTAGCC
TGCCAGTAGCTGCCATCTATGATCTAGATGATATTGAGCAAGCGATTGGTACTAAACATGGCCCAGGTAAAGTGCTTTTA
CGCGGAAAAAATATAGAGGCTTAG

Upstream 100 bases:

>100_bases
GTGTCTCGTAAGATGAAAAGAATGTCTCATTAAATCAAGAAGCAAGTTGAGTTGAAACGTATGATTTTCGCAATCAATTA
AGCACAAAGGAGTCGAAATT

Downstream 100 bases:

>100_bases
CCCGTTTACTCATATTTATTGCTGTAATCAATTAATAGATGCAGTCGCTGCTGCAAGGAGATACCAAGATGAAGATTGAT
ATTTGGTCAGATGTTATTTG

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: ADH-HT [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MRIAVHESLGQPEQVMSIQETSRPTLKAGEVLLQMVLSPIHNHDLMQISGTYGTKPTLPARAGTEALGRVLEVGEGVKDL
QIGQRVAASGAFGTWADAFVAPADQLLPIPDGISDELAAQLLVMPASATVVLDDLGVKSGQWMVLSAAAGAVGKNLALLA
ASRQIRVIGLVNRDSQVKELRALGVDLVENTEKDGWQQRIKTALNGEALLYGLDSVAGELTGEMLSVMNDNATVVVFGAL
SNHPLRIDFQDVIFKQATVRGFWGLRKFAALNNEYKLRMISEIMTMALRDGFSLPVAAIYDLDDIEQAIGTKHGPGKVLL
RGKNIEA

Sequences:

>Translated_327_residues
MRIAVHESLGQPEQVMSIQETSRPTLKAGEVLLQMVLSPIHNHDLMQISGTYGTKPTLPARAGTEALGRVLEVGEGVKDL
QIGQRVAASGAFGTWADAFVAPADQLLPIPDGISDELAAQLLVMPASATVVLDDLGVKSGQWMVLSAAAGAVGKNLALLA
ASRQIRVIGLVNRDSQVKELRALGVDLVENTEKDGWQQRIKTALNGEALLYGLDSVAGELTGEMLSVMNDNATVVVFGAL
SNHPLRIDFQDVIFKQATVRGFWGLRKFAALNNEYKLRMISEIMTMALRDGFSLPVAAIYDLDDIEQAIGTKHGPGKVLL
RGKNIEA
>Mature_327_residues
MRIAVHESLGQPEQVMSIQETSRPTLKAGEVLLQMVLSPIHNHDLMQISGTYGTKPTLPARAGTEALGRVLEVGEGVKDL
QIGQRVAASGAFGTWADAFVAPADQLLPIPDGISDELAAQLLVMPASATVVLDDLGVKSGQWMVLSAAAGAVGKNLALLA
ASRQIRVIGLVNRDSQVKELRALGVDLVENTEKDGWQQRIKTALNGEALLYGLDSVAGELTGEMLSVMNDNATVVVFGAL
SNHPLRIDFQDVIFKQATVRGFWGLRKFAALNNEYKLRMISEIMTMALRDGFSLPVAAIYDLDDIEQAIGTKHGPGKVLL
RGKNIEA

Specific function: Thermophilic NAD(+)-dependent alcohol dehydrogenase. Bears mainly an ethanol-dehydrogenase activity [H]

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI67078404, Length=333, Percent_Identity=25.5255255255255, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI67078406, Length=299, Percent_Identity=26.4214046822742, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI22538446, Length=323, Percent_Identity=28.1733746130031, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI22538444, Length=323, Percent_Identity=28.1733746130031, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI18379349, Length=198, Percent_Identity=29.7979797979798, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI24308257, Length=225, Percent_Identity=25.7777777777778, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536829, Length=276, Percent_Identity=29.7101449275362, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17556000, Length=265, Percent_Identity=24.5283018867925, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17507255, Length=210, Percent_Identity=30.4761904761905, Blast_Score=82, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319520, Length=233, Percent_Identity=24.0343347639485, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319500, Length=307, Percent_Identity=21.4983713355049, Blast_Score=62, Evalue=1e-10,
Organism=Drosophila melanogaster, GI45550423, Length=302, Percent_Identity=27.1523178807947, Blast_Score=106, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 35072; Mature: 35072

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAVHESLGQPEQVMSIQETSRPTLKAGEVLLQMVLSPIHNHDLMQISGTYGTKPTLPA
CEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC
RAGTEALGRVLEVGEGVKDLQIGQRVAASGAFGTWADAFVAPADQLLPIPDGISDELAAQ
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCHHCCCCCCCCCHHHHHH
LLVMPASATVVLDDLGVKSGQWMVLSAAAGAVGKNLALLAASRQIRVIGLVNRDSQVKEL
EEEECCCCEEEEECCCCCCCCEEEEEECCCCCCCCEEEEEECCEEEEEEEECCCHHHHHH
RALGVDLVENTEKDGWQQRIKTALNGEALLYGLDSVAGELTGEMLSVMNDNATVVVFGAL
HHHCCHHHHCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEECC
SNHPLRIDFQDVIFKQATVRGFWGLRKFAALNNEYKLRMISEIMTMALRDGFSLPVAAIY
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
DLDDIEQAIGTKHGPGKVLLRGKNIEA
CHHHHHHHHCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MRIAVHESLGQPEQVMSIQETSRPTLKAGEVLLQMVLSPIHNHDLMQISGTYGTKPTLPA
CEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCC
RAGTEALGRVLEVGEGVKDLQIGQRVAASGAFGTWADAFVAPADQLLPIPDGISDELAAQ
CCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCHHCCCCCCCCCHHHHHH
LLVMPASATVVLDDLGVKSGQWMVLSAAAGAVGKNLALLAASRQIRVIGLVNRDSQVKEL
EEEECCCCEEEEECCCCCCCCEEEEEECCCCCCCCEEEEEECCEEEEEEEECCCHHHHHH
RALGVDLVENTEKDGWQQRIKTALNGEALLYGLDSVAGELTGEMLSVMNDNATVVVFGAL
HHHCCHHHHCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEECC
SNHPLRIDFQDVIFKQATVRGFWGLRKFAALNNEYKLRMISEIMTMALRDGFSLPVAAIY
CCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCEEE
DLDDIEQAIGTKHGPGKVLLRGKNIEA
CHHHHHHHHCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8020473 [H]