Click here to switch to the map view.

The map label for this gene is yajO [H]

Identifier: 157369320

GI number: 157369320

Start: 1184649

End: 1185623

Strand: Reverse

Name: yajO [H]

Synonym: Spro_1077

Alternate gene names: 157369320

Gene position: 1185623-1184649 (Counterclockwise)

Preceding gene: 157369321

Following gene: 157369313

Centisome position: 21.76

GC content: 58.26

Gene sequence:

>975_bases
ATGAAGTATCTGAAACTGGGTAACACCGACCTGAACGTCTCACGTATCTGTCTGGGCTGCATGACCTACGGCGAACCCAG
CCGTGGCAACCATGCCTGGACGTTACCGGAGGAAAGCAGCCGACCGCTGCTGAAACAGGCGCTGGATGCCGGCATCAACT
TCTTTGACACCGCCAACAGCTACTCAGACGGCAGCAGTGAGGAGATCGTCGGCCAGGCACTGCGCGATTATGCCCGCCGT
GACCAGGTAGTGATCGCCACCAAAGTCTATTTCCCCCTGAGTAATCTGCAGCAGGGACTGTCGCGCGCCAAAATCATGCA
ATCTATCGACGACAGCCTCAAGCGGCTGGGCACCGACTACGTTGATCTGTTGCAGATCCATCGCTGGGATTATGAAACGC
CGCTGGAAGAAACGCTCGAAGCGCTGCACGATGTGGTGAAAGCCGGTAAGGCACGCTACATCGGCGCATCGTCAATGTAC
GCCTGGCAGTTCGCCAAGGCGCTGTACACCGCCGATCTGCACGGCTGGACGCGCTTTGTCAGCATGCAAAACCAGTACAA
CCTGATCCAGCGTGAAGAAGAGCGTGAGATGTTACCGCTGTGCGCTGCCGAAGGCATTGCCGTGCTGCCCTGGAGCCCGT
TGGCGCGGGGTCGCTTAACCCGTCCCTGGGGGGAAACCACTGCGCGTCTGGTCTCCGATCAGGTCGGTAAAAATCTGTAC
GATGAAACCGAAGGCATCGACGCCATCATTGCCGAGCGTGTGGCCAGTATTGCCGAAGAACGCGGTGTGCCCCGAGCGCA
AATCGCACTGGCGTGGCTGTTGAGCAAGCCTGTCGTTAGCGCGCCGATTATCGGTGCGTCACGCCATGACCATCTGGAAG
ACGCCGTCGCCGCCGTCGATCTTGAGTTAACACCGGAAGAGATTGCCGAGCTGGAAACGGCTTATGTGCCGCACCACGTG
ACAGGATTTGAATAA

Upstream 100 bases:

>100_bases
GCCCGCTCGATCGACGCCTCCGCTTTGCGGGGGCGTTTTTATTTCTGTCATCCGAAAATCCGCTACAGTTAAAGTTCTGT
GCTGACACCGGGAGGCAAGC

Downstream 100 bases:

>100_bases
CCTGGAGGGTTCAGGGGCGCAGCATTGAACTGCGCCCTCAAAATCAGAACAACCCAAGCGGCCAATGGTGACCAATCAGG
TAGATGATACCGGCGGAAAG

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MKYLKLGNTDLNVSRICLGCMTYGEPSRGNHAWTLPEESSRPLLKQALDAGINFFDTANSYSDGSSEEIVGQALRDYARR
DQVVIATKVYFPLSNLQQGLSRAKIMQSIDDSLKRLGTDYVDLLQIHRWDYETPLEETLEALHDVVKAGKARYIGASSMY
AWQFAKALYTADLHGWTRFVSMQNQYNLIQREEEREMLPLCAAEGIAVLPWSPLARGRLTRPWGETTARLVSDQVGKNLY
DETEGIDAIIAERVASIAEERGVPRAQIALAWLLSKPVVSAPIIGASRHDHLEDAVAAVDLELTPEEIAELETAYVPHHV
TGFE

Sequences:

>Translated_324_residues
MKYLKLGNTDLNVSRICLGCMTYGEPSRGNHAWTLPEESSRPLLKQALDAGINFFDTANSYSDGSSEEIVGQALRDYARR
DQVVIATKVYFPLSNLQQGLSRAKIMQSIDDSLKRLGTDYVDLLQIHRWDYETPLEETLEALHDVVKAGKARYIGASSMY
AWQFAKALYTADLHGWTRFVSMQNQYNLIQREEEREMLPLCAAEGIAVLPWSPLARGRLTRPWGETTARLVSDQVGKNLY
DETEGIDAIIAERVASIAEERGVPRAQIALAWLLSKPVVSAPIIGASRHDHLEDAVAAVDLELTPEEIAELETAYVPHHV
TGFE
>Mature_324_residues
MKYLKLGNTDLNVSRICLGCMTYGEPSRGNHAWTLPEESSRPLLKQALDAGINFFDTANSYSDGSSEEIVGQALRDYARR
DQVVIATKVYFPLSNLQQGLSRAKIMQSIDDSLKRLGTDYVDLLQIHRWDYETPLEETLEALHDVVKAGKARYIGASSMY
AWQFAKALYTADLHGWTRFVSMQNQYNLIQREEEREMLPLCAAEGIAVLPWSPLARGRLTRPWGETTARLVSDQVGKNLY
DETEGIDAIIAERVASIAEERGVPRAQIALAWLLSKPVVSAPIIGASRHDHLEDAVAAVDLELTPEEIAELETAYVPHHV
TGFE

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=326, Percent_Identity=31.2883435582822, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI4504825, Length=324, Percent_Identity=31.1728395061728, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI27436964, Length=325, Percent_Identity=31.3846153846154, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI27436962, Length=325, Percent_Identity=31.0769230769231, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI27436966, Length=325, Percent_Identity=30.7692307692308, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI27436971, Length=324, Percent_Identity=30.2469135802469, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI223718702, Length=280, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI41152114, Length=284, Percent_Identity=29.9295774647887, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI41327764, Length=271, Percent_Identity=28.7822878228782, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI223718708, Length=176, Percent_Identity=33.5227272727273, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=72.5308641975309, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=31.700288184438, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1789375, Length=330, Percent_Identity=32.7272727272727, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788070, Length=325, Percent_Identity=32, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788081, Length=296, Percent_Identity=30.4054054054054, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1787674, Length=322, Percent_Identity=25.776397515528, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI48994888, Length=286, Percent_Identity=26.5734265734266, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786400, Length=286, Percent_Identity=26.5734265734266, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082198, Length=287, Percent_Identity=24.390243902439, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=163, Percent_Identity=36.8098159509202, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17537079, Length=321, Percent_Identity=23.6760124610592, Blast_Score=71, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=341, Percent_Identity=42.5219941348974, Blast_Score=266, Evalue=4e-72,
Organism=Saccharomyces cerevisiae, GI6323998, Length=331, Percent_Identity=33.2326283987915, Blast_Score=163, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6319958, Length=310, Percent_Identity=32.5806451612903, Blast_Score=159, Evalue=5e-40,
Organism=Saccharomyces cerevisiae, GI6319951, Length=325, Percent_Identity=31.3846153846154, Blast_Score=155, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6322615, Length=256, Percent_Identity=32.8125, Blast_Score=136, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6321052, Length=155, Percent_Identity=32.258064516129, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24646155, Length=318, Percent_Identity=31.4465408805031, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI24640980, Length=338, Percent_Identity=26.3313609467456, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45549126, Length=338, Percent_Identity=26.0355029585799, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24646159, Length=164, Percent_Identity=38.4146341463415, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI20129731, Length=319, Percent_Identity=24.4514106583072, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36204; Mature: 36204

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYLKLGNTDLNVSRICLGCMTYGEPSRGNHAWTLPEESSRPLLKQALDAGINFFDTANS
CCEEECCCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHCCCCCCCCCCC
YSDGSSEEIVGQALRDYARRDQVVIATKVYFPLSNLQQGLSRAKIMQSIDDSLKRLGTDY
CCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VDLLQIHRWDYETPLEETLEALHDVVKAGKARYIGASSMYAWQFAKALYTADLHGWTRFV
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHH
SMQNQYNLIQREEEREMLPLCAAEGIAVLPWSPLARGRLTRPWGETTARLVSDQVGKNLY
HHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHCCCCCCCHHHHHHHHHHHHHCCHHH
DETEGIDAIIAERVASIAEERGVPRAQIALAWLLSKPVVSAPIIGASRHDHLEDAVAAVD
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
LELTPEEIAELETAYVPHHVTGFE
CCCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MKYLKLGNTDLNVSRICLGCMTYGEPSRGNHAWTLPEESSRPLLKQALDAGINFFDTANS
CCEEECCCCCCHHHHHHHHHHHCCCCCCCCCEECCCCCCCCHHHHHHHHCCCCCCCCCCC
YSDGSSEEIVGQALRDYARRDQVVIATKVYFPLSNLQQGLSRAKIMQSIDDSLKRLGTDY
CCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
VDLLQIHRWDYETPLEETLEALHDVVKAGKARYIGASSMYAWQFAKALYTADLHGWTRFV
HHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHH
SMQNQYNLIQREEEREMLPLCAAEGIAVLPWSPLARGRLTRPWGETTARLVSDQVGKNLY
HHHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHCCCCCCCHHHHHHHHHHHHHCCHHH
DETEGIDAIIAERVASIAEERGVPRAQIALAWLLSKPVVSAPIIGASRHDHLEDAVAAVD
HHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHC
LELTPEEIAELETAYVPHHVTGFE
CCCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]