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The map label for this gene is nusB

Identifier: 157369317

GI number: 157369317

Start: 1182657

End: 1183073

Strand: Direct

Name: nusB

Synonym: Spro_1074

Alternate gene names: 157369317

Gene position: 1182657-1183073 (Clockwise)

Preceding gene: 157369316

Following gene: 157369318

Centisome position: 21.7

GC content: 53.0

Gene sequence:

>417_bases
GTGAAACCTGCTGCTCGTCGCCGCGCTCGTGAGTGCGCTGTTCAAGCGCTTTACTCTTGGCAGTTGTCTAAAAATGACAT
TGCCGATGTTGAACACCAGTTCCTGTCGGAGCAAGATGTCAAAGATGTAGACATCGTCTATTTTCGGGAGCTGCTGTCCG
GCGTGGCGGTGAATGCAGGTCTGCTGGATAGCCTGATGGCACCTGTCCTGTCGCGTCAGCTCGAAGAGCTGGGCCAGGTA
GAAAGAGCCGTTCTGCGTATTGCGCTGTATGAGCTGAAAATGCGTGAGGATGTGCCTTACAAGGTGGCGATCAACGAGGC
GATCGAGCTGGCGAAAACCTTCGGCGCTGAAGACAGCCACAAGTTTGTGAATGGCGTGCTGGATAAAGTGGCACCAAGCA
TTCGCAAGAAAAAATAA

Upstream 100 bases:

>100_bases
CCAAAGCGGGCAACAAGGGCGCTGAAGCGGCTCTGACCGCACTTGAAATGATTAATGTTATCAAAGCTATTAAAGCCTGA
ATTTAGTTAAGGGGAATTCC

Downstream 100 bases:

>100_bases
AAAATTAAGGCCGGTATCCCCGGCCTTAATTTCTTCTATTGGAATATCGACCATGGCATGTGGCGAATTTGACCTCATTG
CCCGCTATTTTGACCGGTTT

Product: transcription antitermination protein NusB

Products: NA

Alternate protein names: Protein nusB

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MKPAARRRARECAVQALYSWQLSKNDIADVEHQFLSEQDVKDVDIVYFRELLSGVAVNAGLLDSLMAPVLSRQLEELGQV
ERAVLRIALYELKMREDVPYKVAINEAIELAKTFGAEDSHKFVNGVLDKVAPSIRKKK

Sequences:

>Translated_138_residues
MKPAARRRARECAVQALYSWQLSKNDIADVEHQFLSEQDVKDVDIVYFRELLSGVAVNAGLLDSLMAPVLSRQLEELGQV
ERAVLRIALYELKMREDVPYKVAINEAIELAKTFGAEDSHKFVNGVLDKVAPSIRKKK
>Mature_138_residues
MKPAARRRARECAVQALYSWQLSKNDIADVEHQFLSEQDVKDVDIVYFRELLSGVAVNAGLLDSLMAPVLSRQLEELGQV
ERAVLRIALYELKMREDVPYKVAINEAIELAKTFGAEDSHKFVNGVLDKVAPSIRKKK

Specific function: Involved in the transcription termination process

COG id: COG0781

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nusB family

Homologues:

Organism=Escherichia coli, GI1786618, Length=138, Percent_Identity=83.3333333333333, Blast_Score=222, Evalue=6e-60,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NUSB_SERP5 (A8GAN8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001477306.1
- ProteinModelPortal:   A8GAN8
- SMR:   A8GAN8
- STRING:   A8GAN8
- GeneID:   5605253
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_1074
- eggNOG:   COG0781
- HOGENOM:   HBG734409
- OMA:   SHNDIAD
- ProtClustDB:   PRK00202
- BioCyc:   SPRO399741:SPRO_1074-MONOMER
- HAMAP:   MF_00073
- InterPro:   IPR011605
- InterPro:   IPR006027
- Gene3D:   G3DSA:1.10.940.10
- TIGRFAMs:   TIGR01951

Pfam domain/function: PF01029 NusB; SSF48013 NusB_RsmB_TIM44

EC number: NA

Molecular weight: Translated: 15584; Mature: 15584

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPAARRRARECAVQALYSWQLSKNDIADVEHQFLSEQDVKDVDIVYFRELLSGVAVNAG
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LLDSLMAPVLSRQLEELGQVERAVLRIALYELKMREDVPYKVAINEAIELAKTFGAEDSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHH
KFVNGVLDKVAPSIRKKK
HHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPAARRRARECAVQALYSWQLSKNDIADVEHQFLSEQDVKDVDIVYFRELLSGVAVNAG
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LLDSLMAPVLSRQLEELGQVERAVLRIALYELKMREDVPYKVAINEAIELAKTFGAEDSH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHH
KFVNGVLDKVAPSIRKKK
HHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA