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The map label for this gene is malZ [H]

Identifier: 157369292

GI number: 157369292

Start: 1154333

End: 1156156

Strand: Direct

Name: malZ [H]

Synonym: Spro_1049

Alternate gene names: 157369292

Gene position: 1154333-1156156 (Clockwise)

Preceding gene: 157369289

Following gene: 157369303

Centisome position: 21.18

GC content: 59.32

Gene sequence:

>1824_bases
ATGCTTAACGCCTGGCATCAACCGGTCCCGCCCTTCGTGGTGAAGAAGGGGCAACGTCTTGATATCACGCTGTGGTTACA
GGGTGATGATGTGCCCGAACGGGTGTTTTTACGCGCCGAACCGGATAATGAAGAATGGTTGCTGACGATGAAAGTGCAGC
ATATTGACGGGCTGCATCGCTATCAGGCCAGTTTGACGCTCAATGAGGGGGAGCCAACCCGTCGTTACTGCTTCAAGCTG
GTTTGGGCTGCCAGTCAGCAATGGTTCGGCCCCCAGGGTTGGTCGCTGACGCCGCCGGGGCAACTGGCGCAGTTTGCTGT
CGACGTGCCCGACCGCAGCCCGGCCTGGGTGGCGGATCAGGTTTTCTATCAAATTTTCCCCGATCGCTTCTCCAGTAGCG
GGGGGGAACATTGCATTCAAAGTGGCAGTTATCGCCATCATGCGGCCGGTTGCGATGTTGTGCGTCAGGATTGGCACCAT
CCGTTGGAAGACCGGCATGCCGCGTCCACCTTCTATGGTGGCGATCTGGATGGCATCAGCCAAAAACTGCCTTATCTACA
GCAGCTGGGCGTGACGGCGCTGTATCTGAATCCGATTTTCACCGCGCCCAGCGTACATAAATACGATACCGAAGATTATT
ACCAGGTCGATCCCTATCTCGGCGGCAACGCCGCCCTGCAGCGTTTGCGAGTGAGTACTCACAAGGTGGGGATGAAACTG
GTGCTGGACGGGGTGTTTAACCATACCGGCGATTCGCATCCGTGGTTTGACCGCCACCAGCAAGGGGATAACGGCGCTTG
CCATCACCCCGATTCACCTTACCGTGGCTGGTTCAATTTTTACCCCGATGGCCGCGCGCTCGACTGGAAAGGGAATGCCA
GTCTGCCGAAGCTTAACTTCGCTGAACCACAGGTAGCGGAAGCGATTTATCGCGGTGACGGTAGCGTGGTGCGTCACTGG
TTACGGCCGCCGTACAACATCGACGGTTGGCGGCTGGATGTGGTGCACATGCTGGGTGAGAACGGGGGCGCTACCGGCAA
TTTGCAGCATCTGGCGGGCATTTATCAGGCGGTTAAACAGGAAAACCCGCAGGCCTACGTGCTGGGCGAGCATTTTGGCG
ACGCTCGTCGCTGGCTGCATGCCGGCGTGGAAGATGCGGCAATGAATTACATGGGCTTTGCCCTGCCGGTGCGGGGGTTC
CTCGCCGGGCTGGACGTGGCGCACCACCCGGTGCAGCTGGATGCGGCGGACTGCGCCCAGTGGATGGACGGTTATCGGGC
CGGGCTGCCGCATGGCCGTCAGTTGATTCAGTTCAACCAGCTCGACAGCCATGACACTGCGCGCTTTCTGACGCTATTAC
AGGGCAATCAGGCGCGGATGCGCATGGCGGCGGTGTGGCTGATGAGCTGGATAGGCGTACCCTGCCTATATTATGGCGAC
GAGATTGGTCTGGATGGGGCCAACGACCCGTTCTGTCGCAAGCCTTTTCCGTGGGATGAAAGCCAGTGGGATCAGAACCT
GTTGGCCCTGTACCAGCGCATGGCGGCGCTGCGCAAACAGAGCCTGGCGCTGCGTCGCGGCGGTTGTCAGGTGCTGCATG
CCGCCGCTGAAACGCTGGTATTTGTGCGTATTTACCAACAGGAACAGGTGTTGGTGGCGTTACAGCGTGACGGCAGCGGC
AGCGTGACCCTGCCACACGGCCCGTTGCTGGCCGCAGGCCAATGGCAACGGCTGGAAGGGGATGGCGAGTTGAATGACAC
GCAAAACGCGATCTCGCTGCAACTGGGCAAAGAGACGGTAAGCCTGTGGCGGTTAACAGGCTAA

Upstream 100 bases:

>100_bases
GTTTACCGGCCAAAGAGGAGGGGGACTGGCACTCAACGTGGCATTGTTCGTGGCATTGAATAACGTCGTCGATTTCGTTT
TGTACAGCAGGAGGAAAGTC

Downstream 100 bases:

>100_bases
TCTGGCCAGGCTCCCCTTAAAAAACCTGCCCCCAGTTGGCCAACAGCGTCTGCGCCTGTCCGGGCGCAGACCTGAACAAG
TCTACCGCACTGCATAACCT

Product: maltodextrin glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase [H]

Number of amino acids: Translated: 607; Mature: 607

Protein sequence:

>607_residues
MLNAWHQPVPPFVVKKGQRLDITLWLQGDDVPERVFLRAEPDNEEWLLTMKVQHIDGLHRYQASLTLNEGEPTRRYCFKL
VWAASQQWFGPQGWSLTPPGQLAQFAVDVPDRSPAWVADQVFYQIFPDRFSSSGGEHCIQSGSYRHHAAGCDVVRQDWHH
PLEDRHAASTFYGGDLDGISQKLPYLQQLGVTALYLNPIFTAPSVHKYDTEDYYQVDPYLGGNAALQRLRVSTHKVGMKL
VLDGVFNHTGDSHPWFDRHQQGDNGACHHPDSPYRGWFNFYPDGRALDWKGNASLPKLNFAEPQVAEAIYRGDGSVVRHW
LRPPYNIDGWRLDVVHMLGENGGATGNLQHLAGIYQAVKQENPQAYVLGEHFGDARRWLHAGVEDAAMNYMGFALPVRGF
LAGLDVAHHPVQLDAADCAQWMDGYRAGLPHGRQLIQFNQLDSHDTARFLTLLQGNQARMRMAAVWLMSWIGVPCLYYGD
EIGLDGANDPFCRKPFPWDESQWDQNLLALYQRMAALRKQSLALRRGGCQVLHAAAETLVFVRIYQQEQVLVALQRDGSG
SVTLPHGPLLAAGQWQRLEGDGELNDTQNAISLQLGKETVSLWRLTG

Sequences:

>Translated_607_residues
MLNAWHQPVPPFVVKKGQRLDITLWLQGDDVPERVFLRAEPDNEEWLLTMKVQHIDGLHRYQASLTLNEGEPTRRYCFKL
VWAASQQWFGPQGWSLTPPGQLAQFAVDVPDRSPAWVADQVFYQIFPDRFSSSGGEHCIQSGSYRHHAAGCDVVRQDWHH
PLEDRHAASTFYGGDLDGISQKLPYLQQLGVTALYLNPIFTAPSVHKYDTEDYYQVDPYLGGNAALQRLRVSTHKVGMKL
VLDGVFNHTGDSHPWFDRHQQGDNGACHHPDSPYRGWFNFYPDGRALDWKGNASLPKLNFAEPQVAEAIYRGDGSVVRHW
LRPPYNIDGWRLDVVHMLGENGGATGNLQHLAGIYQAVKQENPQAYVLGEHFGDARRWLHAGVEDAAMNYMGFALPVRGF
LAGLDVAHHPVQLDAADCAQWMDGYRAGLPHGRQLIQFNQLDSHDTARFLTLLQGNQARMRMAAVWLMSWIGVPCLYYGD
EIGLDGANDPFCRKPFPWDESQWDQNLLALYQRMAALRKQSLALRRGGCQVLHAAAETLVFVRIYQQEQVLVALQRDGSG
SVTLPHGPLLAAGQWQRLEGDGELNDTQNAISLQLGKETVSLWRLTG
>Mature_607_residues
MLNAWHQPVPPFVVKKGQRLDITLWLQGDDVPERVFLRAEPDNEEWLLTMKVQHIDGLHRYQASLTLNEGEPTRRYCFKL
VWAASQQWFGPQGWSLTPPGQLAQFAVDVPDRSPAWVADQVFYQIFPDRFSSSGGEHCIQSGSYRHHAAGCDVVRQDWHH
PLEDRHAASTFYGGDLDGISQKLPYLQQLGVTALYLNPIFTAPSVHKYDTEDYYQVDPYLGGNAALQRLRVSTHKVGMKL
VLDGVFNHTGDSHPWFDRHQQGDNGACHHPDSPYRGWFNFYPDGRALDWKGNASLPKLNFAEPQVAEAIYRGDGSVVRHW
LRPPYNIDGWRLDVVHMLGENGGATGNLQHLAGIYQAVKQENPQAYVLGEHFGDARRWLHAGVEDAAMNYMGFALPVRGF
LAGLDVAHHPVQLDAADCAQWMDGYRAGLPHGRQLIQFNQLDSHDTARFLTLLQGNQARMRMAAVWLMSWIGVPCLYYGD
EIGLDGANDPFCRKPFPWDESQWDQNLLALYQRMAALRKQSLALRRGGCQVLHAAAETLVFVRIYQQEQVLVALQRDGSG
SVTLPHGPLLAAGQWQRLEGDGELNDTQNAISLQLGKETVSLWRLTG

Specific function: May play a role in regulating the intracellular level of maltotriose. Cleaves glucose from the reducing end of maltotriose and longer maltodextrins with a chain length of up to 7 glucose units [H]

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=469, Percent_Identity=23.0277185501066, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI1786604, Length=589, Percent_Identity=60.4414261460102, Blast_Score=743, Evalue=0.0,
Organism=Escherichia coli, GI1790687, Length=415, Percent_Identity=23.3734939759036, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789995, Length=96, Percent_Identity=38.5416666666667, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6321726, Length=256, Percent_Identity=26.171875, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6322241, Length=265, Percent_Identity=24.9056603773585, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6322021, Length=265, Percent_Identity=24.9056603773585, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6324416, Length=265, Percent_Identity=24.9056603773585, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322245, Length=202, Percent_Identity=29.2079207920792, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6321731, Length=176, Percent_Identity=28.9772727272727, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319776, Length=176, Percent_Identity=28.9772727272727, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24586589, Length=196, Percent_Identity=33.6734693877551, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24586593, Length=556, Percent_Identity=23.021582733813, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24586587, Length=198, Percent_Identity=30.8080808080808, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24586599, Length=500, Percent_Identity=24, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24586591, Length=249, Percent_Identity=26.1044176706827, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24586597, Length=191, Percent_Identity=30.8900523560209, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583745, Length=422, Percent_Identity=22.2748815165877, Blast_Score=80, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24583747, Length=250, Percent_Identity=27.6, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24583749, Length=250, Percent_Identity=27.6, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI45549022, Length=190, Percent_Identity=28.4210526315789, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI221330053, Length=186, Percent_Identity=29.0322580645161, Blast_Score=77, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR004185
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783
- InterPro:   IPR014756
- InterPro:   IPR017069 [H]

Pfam domain/function: PF00128 Alpha-amylase; PF02903 Alpha-amylase_N [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 68410; Mature: 68410

Theoretical pI: Translated: 6.48; Mature: 6.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNAWHQPVPPFVVKKGQRLDITLWLQGDDVPERVFLRAEPDNEEWLLTMKVQHIDGLHR
CCCCCCCCCCHHHHCCCCEEEEEEEECCCCCCCEEEEEECCCCCCEEEEEEEHHCCCHHH
YQASLTLNEGEPTRRYCFKLVWAASQQWFGPQGWSLTPPGQLAQFAVDVPDRSPAWVADQ
EEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCCCCCCHHHHH
VFYQIFPDRFSSSGGEHCIQSGSYRHHAAGCDVVRQDWHHPLEDRHAASTFYGGDLDGIS
HHHHHHHHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCCHHHHH
QKLPYLQQLGVTALYLNPIFTAPSVHKYDTEDYYQVDPYLGGNAALQRLRVSTHKVGMKL
HHCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
VLDGVFNHTGDSHPWFDRHQQGDNGACHHPDSPYRGWFNFYPDGRALDWKGNASLPKLNF
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCCCCCCCC
AEPQVAEAIYRGDGSVVRHWLRPPYNIDGWRLDVVHMLGENGGATGNLQHLAGIYQAVKQ
CCHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHC
ENPQAYVLGEHFGDARRWLHAGVEDAAMNYMGFALPVRGFLAGLDVAHHPVQLDAADCAQ
CCCCEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHH
WMDGYRAGLPHGRQLIQFNQLDSHDTARFLTLLQGNQARMRMAAVWLMSWIGVPCLYYGD
HHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECC
EIGLDGANDPFCRKPFPWDESQWDQNLLALYQRMAALRKQSLALRRGGCQVLHAAAETLV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEE
FVRIYQQEQVLVALQRDGSGSVTLPHGPLLAAGQWQRLEGDGELNDTQNAISLQLGKETV
EEEEECCCEEEEEEEECCCCCEECCCCCEEECCCCEEECCCCCCCCCCCEEEEEECHHEE
SLWRLTG
EEEEECC
>Mature Secondary Structure
MLNAWHQPVPPFVVKKGQRLDITLWLQGDDVPERVFLRAEPDNEEWLLTMKVQHIDGLHR
CCCCCCCCCCHHHHCCCCEEEEEEEECCCCCCCEEEEEECCCCCCEEEEEEEHHCCCHHH
YQASLTLNEGEPTRRYCFKLVWAASQQWFGPQGWSLTPPGQLAQFAVDVPDRSPAWVADQ
EEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHEEEEECCCCCCCHHHHH
VFYQIFPDRFSSSGGEHCIQSGSYRHHAAGCDVVRQDWHHPLEDRHAASTFYGGDLDGIS
HHHHHHHHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHCCCCHHHHHHHHCCCCCCHHHHH
QKLPYLQQLGVTALYLNPIFTAPSVHKYDTEDYYQVDPYLGGNAALQRLRVSTHKVGMKL
HHCHHHHHCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHH
VLDGVFNHTGDSHPWFDRHQQGDNGACHHPDSPYRGWFNFYPDGRALDWKGNASLPKLNF
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEECCCCCCCCCCCC
AEPQVAEAIYRGDGSVVRHWLRPPYNIDGWRLDVVHMLGENGGATGNLQHLAGIYQAVKQ
CCHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHHHHHHHC
ENPQAYVLGEHFGDARRWLHAGVEDAAMNYMGFALPVRGFLAGLDVAHHPVQLDAADCAQ
CCCCEEEECCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHH
WMDGYRAGLPHGRQLIQFNQLDSHDTARFLTLLQGNQARMRMAAVWLMSWIGVPCLYYGD
HHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECC
EIGLDGANDPFCRKPFPWDESQWDQNLLALYQRMAALRKQSLALRRGGCQVLHAAAETLV
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEE
FVRIYQQEQVLVALQRDGSGSVTLPHGPLLAAGQWQRLEGDGELNDTQNAISLQLGKETV
EEEEECCCEEEEEEEECCCCCEECCCCCEEECCCCEEECCCCCCCCCCCEEEEEECHHEE
SLWRLTG
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1918057; 9278503; 1706703 [H]