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The map label for this gene is ampH [H]

Identifier: 157368881

GI number: 157368881

Start: 701674

End: 702816

Strand: Reverse

Name: ampH [H]

Synonym: Spro_0636

Alternate gene names: 157368881

Gene position: 702816-701674 (Counterclockwise)

Preceding gene: 157368882

Following gene: 157368869

Centisome position: 12.9

GC content: 60.19

Gene sequence:

>1143_bases
TTGAAGAACTCTTTCTCCGCTTCATTGCTGGCGCTGAGCCTGTGTGCCGCCCCGCTGGCCGCGCAGGCCGCCGCCCCGCA
GCTGGCCTCGCAAATCGTCGACCAGTATGCCGAACATATTTTCTACAACAGCGGTGCCACCGGTATGGCGCTGGTGGTGA
TCGACGGTAACCAGGTGGTTAACCGCAGTTTTGGCGACACCAAACCCGGCAATAACCTGCGCCCACGCCCGGACTCGCTG
ATCCGCATTGCCTCAATCACCAAACTGATGACCAGTGAAGTGATGGTCAAGATGGCGGCGGAAGGCCGGGTCAAGCTCAA
CGATCCGTTGCGCAAATATGCCCCCCAAGGTGCTTACGTGCCGGCCTATAACACACGCCAGCCGATCACTTTGCTGAACC
TGGCAACCCACACCAGCGCCCTGCCGCGTGAACAGCCGGGCAAGAAGCCGCCAAAAACGCCGGTCTTTACCTGGCCGACC
AAGGCACAGCGCTGGCAGTGGCTGGAACATGCCAACGTCACGGTGCCACCGGGCGTGCGCGCCTCTTATTCCAACCTGGC
GTACGACCTGCTGGCGGATGCACTGTCGCGGGCGGCGGGTAAACCTTACACCGCGCTGCTGAAGGAAAAAATCACCGCAC
CGCTCGGCATGGTCGACACCACTCTCACCCCAAGTGCCGAACAGTGCTCACGCCTGATGGTGGCTTCCGCCGGCCCGAGT
GCCTGCCGTGACACCACAGCCGCGGCCGGTAGCGGCGGCGTTTACTCCACCCCGCGCGACATGCAGCGCTGGATGCAGCA
ATTCCTTACCTCCAATGTCTCTGGCTCACGTAAATCGACCGCCGCCAGCGAACAGACCATGTACTTCCAACGCAACGATC
TGGTCTCGCTAAAAGGCATGGACGTGCCGGGTGAAGCCAGCGCGTTAGGATTGGGCTGGGTGTATATGGCACCGAACGGC
GAACTGCCGGGGATTATTCAGAAAACCGGCGGTGGCGGCGGCTTTATTACCTATATGGCGATGATCCCGCAGAAAAACGT
CGGGGTATTTGTGGTGGTGACCCGCTCGGAACTGAGCAAGTTCACCAACATGAGCGATCCTGTGAACCGACTGGTGAGTG
ATTTGGCGGCGAATAAAAGTTGA

Upstream 100 bases:

>100_bases
GCAGCCAGGGCCGAGGCACATTACACTGACAGCCTATTACGCCGTGTCATGCCACGGCCCAGGCCTTTTCCCTGCTGCCT
TTTAAAATGGATAACGACCG

Downstream 100 bases:

>100_bases
TGTTATCGGGCGCAGCGGTGAGCTGCGCCCATTAGGGTCAGGCCAGAGCCAGCCTTTCGTGCATTACCGGATGGAAGTTG
CGCTTGAAGTAGATCAGGCC

Product: beta-lactam binding protein AmpH

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MKNSFSASLLALSLCAAPLAAQAAAPQLASQIVDQYAEHIFYNSGATGMALVVIDGNQVVNRSFGDTKPGNNLRPRPDSL
IRIASITKLMTSEVMVKMAAEGRVKLNDPLRKYAPQGAYVPAYNTRQPITLLNLATHTSALPREQPGKKPPKTPVFTWPT
KAQRWQWLEHANVTVPPGVRASYSNLAYDLLADALSRAAGKPYTALLKEKITAPLGMVDTTLTPSAEQCSRLMVASAGPS
ACRDTTAAAGSGGVYSTPRDMQRWMQQFLTSNVSGSRKSTAASEQTMYFQRNDLVSLKGMDVPGEASALGLGWVYMAPNG
ELPGIIQKTGGGGGFITYMAMIPQKNVGVFVVVTRSELSKFTNMSDPVNRLVSDLAANKS

Sequences:

>Translated_380_residues
MKNSFSASLLALSLCAAPLAAQAAAPQLASQIVDQYAEHIFYNSGATGMALVVIDGNQVVNRSFGDTKPGNNLRPRPDSL
IRIASITKLMTSEVMVKMAAEGRVKLNDPLRKYAPQGAYVPAYNTRQPITLLNLATHTSALPREQPGKKPPKTPVFTWPT
KAQRWQWLEHANVTVPPGVRASYSNLAYDLLADALSRAAGKPYTALLKEKITAPLGMVDTTLTPSAEQCSRLMVASAGPS
ACRDTTAAAGSGGVYSTPRDMQRWMQQFLTSNVSGSRKSTAASEQTMYFQRNDLVSLKGMDVPGEASALGLGWVYMAPNG
ELPGIIQKTGGGGGFITYMAMIPQKNVGVFVVVTRSELSKFTNMSDPVNRLVSDLAANKS
>Mature_380_residues
MKNSFSASLLALSLCAAPLAAQAAAPQLASQIVDQYAEHIFYNSGATGMALVVIDGNQVVNRSFGDTKPGNNLRPRPDSL
IRIASITKLMTSEVMVKMAAEGRVKLNDPLRKYAPQGAYVPAYNTRQPITLLNLATHTSALPREQPGKKPPKTPVFTWPT
KAQRWQWLEHANVTVPPGVRASYSNLAYDLLADALSRAAGKPYTALLKEKITAPLGMVDTTLTPSAEQCSRLMVASAGPS
ACRDTTAAAGSGGVYSTPRDMQRWMQQFLTSNVSGSRKSTAASEQTMYFQRNDLVSLKGMDVPGEASALGLGWVYMAPNG
ELPGIIQKTGGGGGFITYMAMIPQKNVGVFVVVTRSELSKFTNMSDPVNRLVSDLAANKS

Specific function: Binds penicillin and contributes to the normal morphology [H]

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-lactamase family [H]

Homologues:

Organism=Homo sapiens, GI239747261, Length=357, Percent_Identity=25.7703081232493, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI239752721, Length=357, Percent_Identity=25.7703081232493, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI239741085, Length=357, Percent_Identity=25.7703081232493, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1786574, Length=381, Percent_Identity=64.5669291338583, Blast_Score=490, Evalue=1e-140,
Organism=Escherichia coli, GI1790593, Length=388, Percent_Identity=23.9690721649485, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: NA

Molecular weight: Translated: 40716; Mature: 40716

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNSFSASLLALSLCAAPLAAQAAAPQLASQIVDQYAEHIFYNSGATGMALVVIDGNQVV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCHHC
NRSFGDTKPGNNLRPRPDSLIRIASITKLMTSEVMVKMAAEGRVKLNDPLRKYAPQGAYV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHCCCCCCC
PAYNTRQPITLLNLATHTSALPREQPGKKPPKTPVFTWPTKAQRWQWLEHANVTVPPGVR
CCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCC
ASYSNLAYDLLADALSRAAGKPYTALLKEKITAPLGMVDTTLTPSAEQCSRLMVASAGPS
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCH
ACRDTTAAAGSGGVYSTPRDMQRWMQQFLTSNVSGSRKSTAASEQTMYFQRNDLVSLKGM
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCHHHHEEEECCCEEEEECC
DVPGEASALGLGWVYMAPNGELPGIIQKTGGGGGFITYMAMIPQKNVGVFVVVTRSELSK
CCCCCCCEEEEEEEEECCCCCCCCEEEECCCCCCEEEEEEECCCCCCCEEEEEEHHHHHH
FTNMSDPVNRLVSDLAANKS
HCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNSFSASLLALSLCAAPLAAQAAAPQLASQIVDQYAEHIFYNSGATGMALVVIDGNQVV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCHHC
NRSFGDTKPGNNLRPRPDSLIRIASITKLMTSEVMVKMAAEGRVKLNDPLRKYAPQGAYV
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHCCCCCCC
PAYNTRQPITLLNLATHTSALPREQPGKKPPKTPVFTWPTKAQRWQWLEHANVTVPPGVR
CCCCCCCCEEEEEEHHHHCCCCCCCCCCCCCCCCEEECCCHHHHHHHHHHCCCCCCCCCC
ASYSNLAYDLLADALSRAAGKPYTALLKEKITAPLGMVDTTLTPSAEQCSRLMVASAGPS
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCCH
ACRDTTAAAGSGGVYSTPRDMQRWMQQFLTSNVSGSRKSTAASEQTMYFQRNDLVSLKGM
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCHHHHEEEECCCEEEEECC
DVPGEASALGLGWVYMAPNGELPGIIQKTGGGGGFITYMAMIPQKNVGVFVVVTRSELSK
CCCCCCCEEEEEEEEECCCCCCCCEEEECCCCCCEEEEEEECCCCCCCEEEEEEHHHHHH
FTNMSDPVNRLVSDLAANKS
HCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]