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The map label for this gene is exuR [H]

Identifier: 157368882

GI number: 157368882

Start: 702978

End: 703736

Strand: Reverse

Name: exuR [H]

Synonym: Spro_0637

Alternate gene names: 157368882

Gene position: 703736-702978 (Counterclockwise)

Preceding gene: 157368890

Following gene: 157368881

Centisome position: 12.92

GC content: 60.34

Gene sequence:

>759_bases
ATGCCGATCACCCGACTGGAAAACCCACGTATTTACAGACAGATAGCCGACCAATTGAAGCGGCTCATCGATAATAATGA
ATTTCCTCCGGGCAGCCGCCTGCCGTCCGAGCGGGATCTGGCCCAGCAGTTACAGGTCAGCCGCGCCTCTGTGCGTGAGG
CGCTGATCGCGCTCGAAGTGATTGGTCTGGTGGATGTTAAAGTCGGCAATGGGGTGATTGTCCGGGCACAAACGCCGACC
ATGGTTTCGCAGGAGCCGGTGATGGCGCAGGCCGGGCGCGGTCAGTGGGCAGAAATCGACGATGAGCTGAATATCGAGCT
GGATTTTAACGCCGAGCTGCCGCCGTTCTCACTGCTGCAAACCCGCCTGTTGATCGAACCGGAAACCGCCGCGCTGGCCG
CGCGCCACGCTACCGATCAGGAGCTGGCAGGCATCCGCGATGCCTACGAGCAAAACTGTCGCGATAACCGCGCGGGTTCG
GCTACCCATCCCGGCGATCGGCTATTCCATATCCGTATCGCTCAGGCCAGCGGCAACCCGGCCTACGCGTTTGTCATCGG
TCACCTGCTCGGCCATCGTTACGGCAGCATGTTCCGCGTATTGCAACGCAACTATACGCCGGACGATATGCCGCACCGTT
CCGAACAGGAACACCGGGCTATTCTGGCGGCGATTGAAGCCCGTGACGTGCGCGGCGCACGCAAGGCGATGAAAGCCCAT
CTGGACCAAGTGATCGCCATTTTCACTCGCGCACAGTAG

Upstream 100 bases:

>100_bases
CCGTTTAACCAATTTTTTACACTTGATTAACCATTACTCAAGCGGCTTGAGCCATATTTGTGCGCAATATCACTTAACAT
CGAACAGCCTAAGGTCAAAA

Downstream 100 bases:

>100_bases
GCCGAATGGGCAGCATCGGAGCGGCGGATATTTTTTTTTCAAACCGCTCTTTTTTCCACATGCAGCCAGGGCCGAGGCAC
ATTACACTGACAGCCTATTA

Product: GntR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MPITRLENPRIYRQIADQLKRLIDNNEFPPGSRLPSERDLAQQLQVSRASVREALIALEVIGLVDVKVGNGVIVRAQTPT
MVSQEPVMAQAGRGQWAEIDDELNIELDFNAELPPFSLLQTRLLIEPETAALAARHATDQELAGIRDAYEQNCRDNRAGS
ATHPGDRLFHIRIAQASGNPAYAFVIGHLLGHRYGSMFRVLQRNYTPDDMPHRSEQEHRAILAAIEARDVRGARKAMKAH
LDQVIAIFTRAQ

Sequences:

>Translated_252_residues
MPITRLENPRIYRQIADQLKRLIDNNEFPPGSRLPSERDLAQQLQVSRASVREALIALEVIGLVDVKVGNGVIVRAQTPT
MVSQEPVMAQAGRGQWAEIDDELNIELDFNAELPPFSLLQTRLLIEPETAALAARHATDQELAGIRDAYEQNCRDNRAGS
ATHPGDRLFHIRIAQASGNPAYAFVIGHLLGHRYGSMFRVLQRNYTPDDMPHRSEQEHRAILAAIEARDVRGARKAMKAH
LDQVIAIFTRAQ
>Mature_251_residues
PITRLENPRIYRQIADQLKRLIDNNEFPPGSRLPSERDLAQQLQVSRASVREALIALEVIGLVDVKVGNGVIVRAQTPTM
VSQEPVMAQAGRGQWAEIDDELNIELDFNAELPPFSLLQTRLLIEPETAALAARHATDQELAGIRDAYEQNCRDNRAGSA
THPGDRLFHIRIAQASGNPAYAFVIGHLLGHRYGSMFRVLQRNYTPDDMPHRSEQEHRAILAAIEARDVRGARKAMKAHL
DQVIAIFTRAQ

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=242, Percent_Identity=32.2314049586777, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI87082208, Length=256, Percent_Identity=32.8125, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790032, Length=241, Percent_Identity=31.5352697095436, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1789621, Length=251, Percent_Identity=29.4820717131474, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI48994955, Length=229, Percent_Identity=27.9475982532751, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1786303, Length=190, Percent_Identity=28.9473684210526, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789353, Length=239, Percent_Identity=28.0334728033473, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 28206; Mature: 28075

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPITRLENPRIYRQIADQLKRLIDNNEFPPGSRLPSERDLAQQLQVSRASVREALIALEV
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGLVDVKVGNGVIVRAQTPTMVSQEPVMAQAGRGQWAEIDDELNIELDFNAELPPFSLLQ
HHHEEEEECCCEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHH
TRLLIEPETAALAARHATDQELAGIRDAYEQNCRDNRAGSATHPGDRLFHIRIAQASGNP
HHHEECCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCC
AYAFVIGHLLGHRYGSMFRVLQRNYTPDDMPHRSEQEHRAILAAIEARDVRGARKAMKAH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LDQVIAIFTRAQ
HHHHHHHHHCCC
>Mature Secondary Structure 
PITRLENPRIYRQIADQLKRLIDNNEFPPGSRLPSERDLAQQLQVSRASVREALIALEV
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
IGLVDVKVGNGVIVRAQTPTMVSQEPVMAQAGRGQWAEIDDELNIELDFNAELPPFSLLQ
HHHEEEEECCCEEEEECCCCCCCCCCHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHH
TRLLIEPETAALAARHATDQELAGIRDAYEQNCRDNRAGSATHPGDRLFHIRIAQASGNP
HHHEECCHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEECCCCC
AYAFVIGHLLGHRYGSMFRVLQRNYTPDDMPHRSEQEHRAILAAIEARDVRGARKAMKAH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LDQVIAIFTRAQ
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA