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The map label for this gene is argI [H]

Identifier: 157368799

GI number: 157368799

Start: 613267

End: 614286

Strand: Reverse

Name: argI [H]

Synonym: Spro_0554

Alternate gene names: 157368799

Gene position: 614286-613267 (Counterclockwise)

Preceding gene: 157368802

Following gene: 157368798

Centisome position: 11.27

GC content: 57.94

Gene sequence:

>1020_bases
ATGAGTAGCATAAACCCGTTCTACAAACGTCACTTCCTGAGGTTAATGGATTTCACCCCGGCACAGCTGCATGCGCTGCT
GAAACTGTCGGCCGACTTGAAGCAGGCCAAGAAGCAAGGCAAGGAAGTACGCCACCTGCAGGGCAAAAACATCGCGCTCA
TCTTCGAAAAAGACTCGACCCGTACCCGATGCTCTTTCGAAGTTGCCGCATTCGATCAGGGTGCTCAGGTCACCTATCTC
GGTCCGAGCGGCAGCCAGATTGGCCACAAGGAATCGATGAAAGACACCGCCCGCGTGCTGGGCCGGATGTATGACGGTAT
TCAGTACCGCGGGTACGGCCAGCATCTGGTGGAAACCCTGGCCCAGCATGCCGGCGTGCCGGTGTGGAACGGGCTGACCA
ATGAGTTCCACCCCACCCAATTGCTGGCAGACCTGCTCACGGTACAGGAACAGTTGCCGGGCAAGCCGCTGAGCGAGGTG
AAGTTCGCCTACCTCGGCGATACCCGCAACAATATGGGCAACACCCTGCTGGAAGCCGCCGCACTGGCGGGAATGGATCT
GCGTCTGGTGGCGCCAAAGGCCTGCTGGCCGCAGCCGGAACTGGTGGCAGAGTGCCAGGCATTAGCCAAACAGACCGGGG
CCAAAATCACCCTGACCGAAGATATTGCCGAAGGGGTGAAGGACGCGGACTTTCTGTATACCGACGTCTGGGTGTCGATG
GGTGAACCCAAAGAAACCTGGCACGAGCGTATTGGGCTGTTGAAACCCTATCAGGTCAATATGGCGATGGTGAAACTGAC
CGGCAACCCGAACGTTAAATTCCTGCACTGTCTGCCGGCGTTTCACGACGACCAAACCACCCTCGGCAAGCAGATGGCAG
AGCAATACGGGCTGCATGGCGGCATGGAAGTGACCGATGAAGTGTTCGAGTCCGCGCACAGCGTGGTGTTCGATCAGGCA
GAAAACCGTCTGCACACCATCAAGGCGGTGATGGTCGCCACCCTGAGCGAAACGCTTTAA

Upstream 100 bases:

>100_bases
CCACGATAAACGTGAAAGATTTCCATCCCGGGGTTGAAATTGAATATTCATACATATAAAGTGAATTTAAATTCAATTCA
AGCAATAAGGATATACGGCA

Downstream 100 bases:

>100_bases
CCATTAACTCCCACACATATTGCCGGGGCGCGTCACGCACGGGCAATGGGGAGCGCGGGTTTGCAGACTCGCGCTCCCCT
CCTCTCTGGCAACCCCTGCC

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSSINPFYKRHFLRLMDFTPAQLHALLKLSADLKQAKKQGKEVRHLQGKNIALIFEKDSTRTRCSFEVAAFDQGAQVTYL
GPSGSQIGHKESMKDTARVLGRMYDGIQYRGYGQHLVETLAQHAGVPVWNGLTNEFHPTQLLADLLTVQEQLPGKPLSEV
KFAYLGDTRNNMGNTLLEAAALAGMDLRLVAPKACWPQPELVAECQALAKQTGAKITLTEDIAEGVKDADFLYTDVWVSM
GEPKETWHERIGLLKPYQVNMAMVKLTGNPNVKFLHCLPAFHDDQTTLGKQMAEQYGLHGGMEVTDEVFESAHSVVFDQA
ENRLHTIKAVMVATLSETL

Sequences:

>Translated_339_residues
MSSINPFYKRHFLRLMDFTPAQLHALLKLSADLKQAKKQGKEVRHLQGKNIALIFEKDSTRTRCSFEVAAFDQGAQVTYL
GPSGSQIGHKESMKDTARVLGRMYDGIQYRGYGQHLVETLAQHAGVPVWNGLTNEFHPTQLLADLLTVQEQLPGKPLSEV
KFAYLGDTRNNMGNTLLEAAALAGMDLRLVAPKACWPQPELVAECQALAKQTGAKITLTEDIAEGVKDADFLYTDVWVSM
GEPKETWHERIGLLKPYQVNMAMVKLTGNPNVKFLHCLPAFHDDQTTLGKQMAEQYGLHGGMEVTDEVFESAHSVVFDQA
ENRLHTIKAVMVATLSETL
>Mature_338_residues
SSINPFYKRHFLRLMDFTPAQLHALLKLSADLKQAKKQGKEVRHLQGKNIALIFEKDSTRTRCSFEVAAFDQGAQVTYLG
PSGSQIGHKESMKDTARVLGRMYDGIQYRGYGQHLVETLAQHAGVPVWNGLTNEFHPTQLLADLLTVQEQLPGKPLSEVK
FAYLGDTRNNMGNTLLEAAALAGMDLRLVAPKACWPQPELVAECQALAKQTGAKITLTEDIAEGVKDADFLYTDVWVSMG
EPKETWHERIGLLKPYQVNMAMVKLTGNPNVKFLHCLPAFHDDQTTLGKQMAEQYGLHGGMEVTDEVFESAHSVVFDQAE
NRLHTIKAVMVATLSETL

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=329, Percent_Identity=37.9939209726444, Blast_Score=199, Evalue=3e-51,
Organism=Homo sapiens, GI18105007, Length=330, Percent_Identity=26.3636363636364, Blast_Score=83, Evalue=3e-16,
Organism=Escherichia coli, GI1790703, Length=334, Percent_Identity=77.2455089820359, Blast_Score=559, Evalue=1e-161,
Organism=Escherichia coli, GI1786469, Length=334, Percent_Identity=77.8443113772455, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI2367364, Length=342, Percent_Identity=28.3625730994152, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI48994908, Length=373, Percent_Identity=23.8605898123324, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322373, Length=333, Percent_Identity=32.7327327327327, Blast_Score=166, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6322331, Length=170, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24642586, Length=227, Percent_Identity=27.3127753303965, Blast_Score=71, Evalue=9e-13,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37695; Mature: 37563

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSINPFYKRHFLRLMDFTPAQLHALLKLSADLKQAKKQGKEVRHLQGKNIALIFEKDST
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
RTRCSFEVAAFDQGAQVTYLGPSGSQIGHKESMKDTARVLGRMYDGIQYRGYGQHLVETL
CCEEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AQHAGVPVWNGLTNEFHPTQLLADLLTVQEQLPGKPLSEVKFAYLGDTRNNMGNTLLEAA
HHHCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHEEEECCCCCHHHHHHHHHH
ALAGMDLRLVAPKACWPQPELVAECQALAKQTGAKITLTEDIAEGVKDADFLYTDVWVSM
HHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCCCHHHHHHHHHHHCC
GEPKETWHERIGLLKPYQVNMAMVKLTGNPNVKFLHCLPAFHDDQTTLGKQMAEQYGLHG
CCCHHHHHHHHCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
GMEVTDEVFESAHSVVFDQAENRLHTIKAVMVATLSETL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSINPFYKRHFLRLMDFTPAQLHALLKLSADLKQAKKQGKEVRHLQGKNIALIFEKDST
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
RTRCSFEVAAFDQGAQVTYLGPSGSQIGHKESMKDTARVLGRMYDGIQYRGYGQHLVETL
CCEEEEEEEECCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
AQHAGVPVWNGLTNEFHPTQLLADLLTVQEQLPGKPLSEVKFAYLGDTRNNMGNTLLEAA
HHHCCCCEECCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHEEEECCCCCHHHHHHHHHH
ALAGMDLRLVAPKACWPQPELVAECQALAKQTGAKITLTEDIAEGVKDADFLYTDVWVSM
HHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEHHHHHCCCCHHHHHHHHHHHCC
GEPKETWHERIGLLKPYQVNMAMVKLTGNPNVKFLHCLPAFHDDQTTLGKQMAEQYGLHG
CCCHHHHHHHHCCCCCEEEEEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
GMEVTDEVFESAHSVVFDQAENRLHTIKAVMVATLSETL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA