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The map label for this gene is treC [H]

Identifier: 157368775

GI number: 157368775

Start: 580232

End: 581896

Strand: Reverse

Name: treC [H]

Synonym: Spro_0528

Alternate gene names: 157368775

Gene position: 581896-580232 (Counterclockwise)

Preceding gene: 157368776

Following gene: 157368773

Centisome position: 10.68

GC content: 59.28

Gene sequence:

>1665_bases
ATGAGCAATCCAATCCCCTGGTGGCAGAACGGCGTCATCTATCAAATCTATCCGAAGAGTTTTCAGGACAGCACCGGTAA
CGGTTACGGCGATCTGGCCGGTGTGACGGAGCGGCTGGACTACCTGCAGGAACTGGGCATCGACGCCATTTGGCTGACGC
CGGTGTATGTCTCGCCGCAGGTGGACAACGGTTATGACGTGGCAGACTACTGCGCCATCGATCCTGCCTACGGCACCATG
GAGGATTTTGATCGGCTGATTGCCGCCGCCCACCAGCGCAGCATCCGCATCGTGATGGATATGGTGTTCAACCACACTTC
GACCGAACACCCGTGGTTTAAAGCCTCGCAGGATCCTGAAAGCCCGTTCCGCCAGTTTTATGTCTGGCGCGACGGCGAAG
GCGATGCCCTGCCGAACAACTGGCGCTCCAAGTTTGGCGGCAACGCCTGGCAGTGGCACGCCGACAGTGGCCAGTATTAT
CTGCACCTGTTTGCCACCGAGCAGGCAGATCTCAACTGGGAGCACCCACCGGTGCGCGAAGAGCTGAAGAAGGTTTGTCA
GTTCTGGGCCGACAAAGGCGTCGACGGTCTGCGTCTGGACGTGATCAACCTGGTCTCCAAACAGCAGGATTTCCCGTCCG
ATAACCTGGGCGATGGCCGCCGTTTCTACACCGATGGCCCACGCATTCATGAATTTCTGCAGGAAATGAGCCGCGACGTG
TTTCAGCCGCGTGGCCTGATGACCGTCGGTGAAATGTCCTCCACCACGCTGGAACATTGCCGGCAGTACGCGGCGCAAAG
CGGCGAAGAGCTGTCGATGACTTTCAACTTCCACCACCTGAAGGTGGACTATGCCGGCGGCGAAAAATGGACGCTGGCGG
CGCCGAATTACGTCGAACTCAAACAGATTTTCAGCCATTGGCAGCAAGGCATGCACAATCAGGCGTGGAACGCGCTGTTT
TGGTGTAACCACGATCAGCCACGTATCGTTTCACGCTTCGGTGACGAGGGTGAACTGCGGGTGCCGGCCGCCAAGATGCT
GGCGATGGTGCTGCATGGCATGCAGGGCACGCCTTATATTTATCAGGGCGAAGAGATCGGCATGACCAATCCGGGCTTTA
ACTCCATAGAACAGTATCGCGATGTGGAAAGCCTGAACATGTACGCCGAACTCAGCGCGCAGGGGAAAAGTGACGCCGAG
CTGCTGGCGATCCTGGCCAGCAAATCCCGCGATAACGGCCGCACGCCAATGCAGTGGAGTAGCGCGCCAAACGCCGGTTT
CACCCAGGGCACGCCGTGGATTAGTTGTGCGGAAAACTATCCGCAGATCAACGCCGAAGCGGCGCTGGCCGATCTGGATT
CGGTGTTTTACGCCTATCGTCAGTTAATCACCCTGCGCAAACAGTACCCACTGCTGACCCACGGTGACTACCGTGACCTG
GCCCCTGCTCACCCGGCGTTGTGGTGCTATCAACGCAGCTGGAATGGCCAGCGCCTGCTGGTGGTGGCCAACCTCAGCCG
CGAGCCGCTTGCCTGGCAGGCCGAAGGTGTGGAGCCGTCTGCTTTATGGCGGCCGCTGATGGGCAACTACGCCGACGCCC
CAGCCCAGCCGCAGGCCACCAGCTTACGCCCGTTCGAAGCGGTGTGGTGGTTGCTGGAAGACTAA

Upstream 100 bases:

>100_bases
ACTGACCATCATGGTTTACAAACGCAAGGCCAGCCGCGGTGAGCTGCCGGTCTGATTGAAATGTAGGGGCCCGGTACGCC
GGGTCTATTAAGGTATTTAT

Downstream 100 bases:

>100_bases
TGCTGTCGGGGCGTGGCCGGCTGCGCCCTACAGTTTTTTCAGCAGCTCCACCACGCCGGCAGCCTCTTGCGCCAGGCGTT
CATCGCTCATATCAAACACC

Product: trehalose-6-phosphate hydrolase

Products: NA

Alternate protein names: Alpha,alpha-phosphotrehalase [H]

Number of amino acids: Translated: 554; Mature: 553

Protein sequence:

>554_residues
MSNPIPWWQNGVIYQIYPKSFQDSTGNGYGDLAGVTERLDYLQELGIDAIWLTPVYVSPQVDNGYDVADYCAIDPAYGTM
EDFDRLIAAAHQRSIRIVMDMVFNHTSTEHPWFKASQDPESPFRQFYVWRDGEGDALPNNWRSKFGGNAWQWHADSGQYY
LHLFATEQADLNWEHPPVREELKKVCQFWADKGVDGLRLDVINLVSKQQDFPSDNLGDGRRFYTDGPRIHEFLQEMSRDV
FQPRGLMTVGEMSSTTLEHCRQYAAQSGEELSMTFNFHHLKVDYAGGEKWTLAAPNYVELKQIFSHWQQGMHNQAWNALF
WCNHDQPRIVSRFGDEGELRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPGFNSIEQYRDVESLNMYAELSAQGKSDAE
LLAILASKSRDNGRTPMQWSSAPNAGFTQGTPWISCAENYPQINAEAALADLDSVFYAYRQLITLRKQYPLLTHGDYRDL
APAHPALWCYQRSWNGQRLLVVANLSREPLAWQAEGVEPSALWRPLMGNYADAPAQPQATSLRPFEAVWWLLED

Sequences:

>Translated_554_residues
MSNPIPWWQNGVIYQIYPKSFQDSTGNGYGDLAGVTERLDYLQELGIDAIWLTPVYVSPQVDNGYDVADYCAIDPAYGTM
EDFDRLIAAAHQRSIRIVMDMVFNHTSTEHPWFKASQDPESPFRQFYVWRDGEGDALPNNWRSKFGGNAWQWHADSGQYY
LHLFATEQADLNWEHPPVREELKKVCQFWADKGVDGLRLDVINLVSKQQDFPSDNLGDGRRFYTDGPRIHEFLQEMSRDV
FQPRGLMTVGEMSSTTLEHCRQYAAQSGEELSMTFNFHHLKVDYAGGEKWTLAAPNYVELKQIFSHWQQGMHNQAWNALF
WCNHDQPRIVSRFGDEGELRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPGFNSIEQYRDVESLNMYAELSAQGKSDAE
LLAILASKSRDNGRTPMQWSSAPNAGFTQGTPWISCAENYPQINAEAALADLDSVFYAYRQLITLRKQYPLLTHGDYRDL
APAHPALWCYQRSWNGQRLLVVANLSREPLAWQAEGVEPSALWRPLMGNYADAPAQPQATSLRPFEAVWWLLED
>Mature_553_residues
SNPIPWWQNGVIYQIYPKSFQDSTGNGYGDLAGVTERLDYLQELGIDAIWLTPVYVSPQVDNGYDVADYCAIDPAYGTME
DFDRLIAAAHQRSIRIVMDMVFNHTSTEHPWFKASQDPESPFRQFYVWRDGEGDALPNNWRSKFGGNAWQWHADSGQYYL
HLFATEQADLNWEHPPVREELKKVCQFWADKGVDGLRLDVINLVSKQQDFPSDNLGDGRRFYTDGPRIHEFLQEMSRDVF
QPRGLMTVGEMSSTTLEHCRQYAAQSGEELSMTFNFHHLKVDYAGGEKWTLAAPNYVELKQIFSHWQQGMHNQAWNALFW
CNHDQPRIVSRFGDEGELRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPGFNSIEQYRDVESLNMYAELSAQGKSDAEL
LAILASKSRDNGRTPMQWSSAPNAGFTQGTPWISCAENYPQINAEAALADLDSVFYAYRQLITLRKQYPLLTHGDYRDLA
PAHPALWCYQRSWNGQRLLVVANLSREPLAWQAEGVEPSALWRPLMGNYADAPAQPQATSLRPFEAVWWLLED

Specific function: Unknown

COG id: COG0366

COG function: function code G; Glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 13 family [H]

Homologues:

Organism=Homo sapiens, GI187423904, Length=566, Percent_Identity=27.0318021201413, Blast_Score=234, Evalue=2e-61,
Organism=Homo sapiens, GI61744481, Length=112, Percent_Identity=36.6071428571429, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI61744475, Length=112, Percent_Identity=36.6071428571429, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI61744479, Length=112, Percent_Identity=36.6071428571429, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI65506891, Length=112, Percent_Identity=36.6071428571429, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI61744483, Length=112, Percent_Identity=36.6071428571429, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI61744477, Length=112, Percent_Identity=36.6071428571429, Blast_Score=82, Evalue=2e-15,
Organism=Escherichia coli, GI1790687, Length=551, Percent_Identity=72.7767695099818, Blast_Score=846, Evalue=0.0,
Organism=Escherichia coli, GI1786604, Length=116, Percent_Identity=40.5172413793103, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1789995, Length=91, Percent_Identity=36.2637362637363, Blast_Score=65, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI25147709, Length=479, Percent_Identity=26.0960334029228, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI32565753, Length=385, Percent_Identity=23.3766233766234, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6322245, Length=583, Percent_Identity=37.3927958833619, Blast_Score=371, Evalue=1e-103,
Organism=Saccharomyces cerevisiae, GI6321726, Length=578, Percent_Identity=35.4671280276817, Blast_Score=351, Evalue=1e-97,
Organism=Saccharomyces cerevisiae, GI6322241, Length=581, Percent_Identity=36.8330464716007, Blast_Score=347, Evalue=4e-96,
Organism=Saccharomyces cerevisiae, GI6322021, Length=581, Percent_Identity=36.8330464716007, Blast_Score=347, Evalue=4e-96,
Organism=Saccharomyces cerevisiae, GI6324416, Length=581, Percent_Identity=36.8330464716007, Blast_Score=346, Evalue=5e-96,
Organism=Saccharomyces cerevisiae, GI6321731, Length=580, Percent_Identity=35.3448275862069, Blast_Score=328, Evalue=2e-90,
Organism=Saccharomyces cerevisiae, GI6319776, Length=580, Percent_Identity=35.1724137931034, Blast_Score=327, Evalue=4e-90,
Organism=Drosophila melanogaster, GI221330053, Length=498, Percent_Identity=36.3453815261044, Blast_Score=288, Evalue=8e-78,
Organism=Drosophila melanogaster, GI24583747, Length=563, Percent_Identity=35.1687388987567, Blast_Score=278, Evalue=6e-75,
Organism=Drosophila melanogaster, GI24583749, Length=563, Percent_Identity=35.1687388987567, Blast_Score=278, Evalue=8e-75,
Organism=Drosophila melanogaster, GI24583745, Length=546, Percent_Identity=34.0659340659341, Blast_Score=275, Evalue=4e-74,
Organism=Drosophila melanogaster, GI24586599, Length=527, Percent_Identity=33.965844402277, Blast_Score=274, Evalue=1e-73,
Organism=Drosophila melanogaster, GI24586593, Length=495, Percent_Identity=34.1414141414141, Blast_Score=267, Evalue=2e-71,
Organism=Drosophila melanogaster, GI45549022, Length=525, Percent_Identity=33.5238095238095, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24586597, Length=501, Percent_Identity=33.9321357285429, Blast_Score=266, Evalue=4e-71,
Organism=Drosophila melanogaster, GI24586589, Length=518, Percent_Identity=35.1351351351351, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI24586591, Length=492, Percent_Identity=33.3333333333333, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24586587, Length=502, Percent_Identity=31.2749003984064, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI281360393, Length=438, Percent_Identity=31.2785388127854, Blast_Score=192, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013780
- InterPro:   IPR006047
- InterPro:   IPR006589
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR012769 [H]

Pfam domain/function: PF00128 Alpha-amylase [H]

EC number: =3.2.1.93 [H]

Molecular weight: Translated: 63295; Mature: 63164

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPIPWWQNGVIYQIYPKSFQDSTGNGYGDLAGVTERLDYLQELGIDAIWLTPVYVSPQ
CCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVADYCAIDPAYGTMEDFDRLIAAAHQRSIRIVMDMVFNHTSTEHPWFKASQDPE
CCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SPFRQFYVWRDGEGDALPNNWRSKFGGNAWQWHADSGQYYLHLFATEQADLNWEHPPVRE
CHHHEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCHHH
ELKKVCQFWADKGVDGLRLDVINLVSKQQDFPSDNLGDGRRFYTDGPRIHEFLQEMSRDV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHH
FQPRGLMTVGEMSSTTLEHCRQYAAQSGEELSMTFNFHHLKVDYAGGEKWTLAAPNYVEL
HCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCEEEEECCCHHHH
KQIFSHWQQGMHNQAWNALFWCNHDQPRIVSRFGDEGELRVPAAKMLAMVLHGMQGTPYI
HHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCEE
YQGEEIGMTNPGFNSIEQYRDVESLNMYAELSAQGKSDAELLAILASKSRDNGRTPMQWS
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCCCCCEEC
SAPNAGFTQGTPWISCAENYPQINAEAALADLDSVFYAYRQLITLRKQYPLLTHGDYRDL
CCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
APAHPALWCYQRSWNGQRLLVVANLSREPLAWQAEGVEPSALWRPLMGNYADAPAQPQAT
CCCCCCEEEEEECCCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCC
SLRPFEAVWWLLED
CCCCHHHEEEEECC
>Mature Secondary Structure 
SNPIPWWQNGVIYQIYPKSFQDSTGNGYGDLAGVTERLDYLQELGIDAIWLTPVYVSPQ
CCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEEEECCC
VDNGYDVADYCAIDPAYGTMEDFDRLIAAAHQRSIRIVMDMVFNHTSTEHPWFKASQDPE
CCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SPFRQFYVWRDGEGDALPNNWRSKFGGNAWQWHADSGQYYLHLFATEQADLNWEHPPVRE
CHHHEEEEEECCCCCCCCCHHHHHCCCCEEEEECCCCCEEEEEEEECCCCCCCCCCCHHH
ELKKVCQFWADKGVDGLRLDVINLVSKQQDFPSDNLGDGRRFYTDGPRIHEFLQEMSRDV
HHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHH
FQPRGLMTVGEMSSTTLEHCRQYAAQSGEELSMTFNFHHLKVDYAGGEKWTLAAPNYVEL
HCCCCCEEECCCHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEECCCCEEEEECCCHHHH
KQIFSHWQQGMHNQAWNALFWCNHDQPRIVSRFGDEGELRVPAAKMLAMVLHGMQGTPYI
HHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHCCCCCCEECCHHHHHHHHHHCCCCCCEE
YQGEEIGMTNPGFNSIEQYRDVESLNMYAELSAQGKSDAELLAILASKSRDNGRTPMQWS
ECCCCCCCCCCCHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHCCCCCCCCCCEEC
SAPNAGFTQGTPWISCAENYPQINAEAALADLDSVFYAYRQLITLRKQYPLLTHGDYRDL
CCCCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
APAHPALWCYQRSWNGQRLLVVANLSREPLAWQAEGVEPSALWRPLMGNYADAPAQPQAT
CCCCCCEEEEEECCCCCEEEEEECCCCCCCEEECCCCCHHHHHHHHHCCCCCCCCCCCCC
SLRPFEAVWWLLED
CCCCHHHEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8083158; 7610040; 9278503; 8421692 [H]