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The map label for this gene is ltrA [H]

Identifier: 157368773

GI number: 157368773

Start: 578667

End: 579575

Strand: Reverse

Name: ltrA [H]

Synonym: Spro_0526

Alternate gene names: 157368773

Gene position: 579575-578667 (Counterclockwise)

Preceding gene: 157368775

Following gene: 157368772

Centisome position: 10.64

GC content: 64.25

Gene sequence:

>909_bases
ATGTCGCTGCCCTTTGATGTGCACCGCCTGCTGCCGGCCTTCCTTGCTGCCGCCCAGGCGCAGAACTTTTCCGCCGCCGC
ACGTCAATTGGGCGTCACGCCAGCGGCCATCAGCAAGAATATCCGCGTGCTGGAAGAAAAACTGGCGCTGCGGCTGTTCC
AGCGTAACACCCACAACGTGGTGCTGACCGATGAAGGCAAGGCCCTGTTGCAACAGGTAGCGCCGTTGTGGCAGGCACTG
TCCGCCACGCTGGAAACCGCCGGCAGCGCGCAACAAGCCCCTTCCGGTACGGTGCGCGTCAGCATGATCCCGGGTTTCGG
CCGCCAGATGCTGATGCCATTGATCCCGCAGTTCCTTGAACGCTACCCGCAGATCGACCTGGATCTTTCGCTGGATGCGC
GGGTGGTCAATCTGGTGGGGGAAGGTTTTGATGTGGGGATCGGCAGCCGGGTCGATCCCGACAGCCGGCTGGTGGCGCGA
TCCTTGTACCCGATGCAGATGGTGTTGGCGGCCTCGCCCGGCTATCTGGCGCAGCACGGCATACCGCAGGATCCGCAAGA
TCTGTTGCAGCACAACTGCCTGTTGCATCGCAACCCGGCCACCGGTCGCAGCGTAAAATGGCCGCTGCAACAACAGGGCG
AAGCCAAAGCGCTGGAGCTGCAGGGCCGTCTGGTAGCCAGCCGCCCGGAAATGCTGCTGGATGCGGCGCTGGCCGGGCTG
GGCATCGTCTGCCTGGCCCGTTGGTACGCAGAGCATCATTTTGCACAAGGCACCCTGCAGCCGGTGCTGGCGGATTGCTG
GCCGCGGCCGACCCAACTGTGGCTGTACTATGCCTCCGCCGATCTGCCGCCGCGGGTGCGCGTCTGGGTTGAGTTCCTAC
TCGAGCATTTCCGTCACCGCCCGGCCTGA

Upstream 100 bases:

>100_bases
GATCCTTGATTTAAATTTGATATCGCATTTTTCCATTTCTCACGCGCCGGGTGTAGGCTGTTAGTTGTCACTTTAATTTC
AACCGAAAGTATCAACCACT

Downstream 100 bases:

>100_bases
GTTTTCAGGCCAAAAATTCAGGCTTGTACAGCTAACGCCCGCTCTTTCCATTTCCTTGTTCTACGTCAAAAGAATCTCGC
CAATATCTATATATAGTGCA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSLPFDVHRLLPAFLAAAQAQNFSAAARQLGVTPAAISKNIRVLEEKLALRLFQRNTHNVVLTDEGKALLQQVAPLWQAL
SATLETAGSAQQAPSGTVRVSMIPGFGRQMLMPLIPQFLERYPQIDLDLSLDARVVNLVGEGFDVGIGSRVDPDSRLVAR
SLYPMQMVLAASPGYLAQHGIPQDPQDLLQHNCLLHRNPATGRSVKWPLQQQGEAKALELQGRLVASRPEMLLDAALAGL
GIVCLARWYAEHHFAQGTLQPVLADCWPRPTQLWLYYASADLPPRVRVWVEFLLEHFRHRPA

Sequences:

>Translated_302_residues
MSLPFDVHRLLPAFLAAAQAQNFSAAARQLGVTPAAISKNIRVLEEKLALRLFQRNTHNVVLTDEGKALLQQVAPLWQAL
SATLETAGSAQQAPSGTVRVSMIPGFGRQMLMPLIPQFLERYPQIDLDLSLDARVVNLVGEGFDVGIGSRVDPDSRLVAR
SLYPMQMVLAASPGYLAQHGIPQDPQDLLQHNCLLHRNPATGRSVKWPLQQQGEAKALELQGRLVASRPEMLLDAALAGL
GIVCLARWYAEHHFAQGTLQPVLADCWPRPTQLWLYYASADLPPRVRVWVEFLLEHFRHRPA
>Mature_301_residues
SLPFDVHRLLPAFLAAAQAQNFSAAARQLGVTPAAISKNIRVLEEKLALRLFQRNTHNVVLTDEGKALLQQVAPLWQALS
ATLETAGSAQQAPSGTVRVSMIPGFGRQMLMPLIPQFLERYPQIDLDLSLDARVVNLVGEGFDVGIGSRVDPDSRLVARS
LYPMQMVLAASPGYLAQHGIPQDPQDLLQHNCLLHRNPATGRSVKWPLQQQGEAKALELQGRLVASRPEMLLDAALAGLG
IVCLARWYAEHHFAQGTLQPVLADCWPRPTQLWLYYASADLPPRVRVWVEFLLEHFRHRPA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=31.1864406779661, Blast_Score=155, Evalue=4e-39,
Organism=Escherichia coli, GI1787128, Length=298, Percent_Identity=28.8590604026846, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87081978, Length=295, Percent_Identity=32.5423728813559, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1787589, Length=270, Percent_Identity=29.2592592592593, Blast_Score=141, Evalue=4e-35,
Organism=Escherichia coli, GI145693193, Length=285, Percent_Identity=31.9298245614035, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1789440, Length=284, Percent_Identity=28.169014084507, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789639, Length=289, Percent_Identity=28.3737024221453, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1788706, Length=300, Percent_Identity=26.6666666666667, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1786448, Length=255, Percent_Identity=29.8039215686275, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1789173, Length=249, Percent_Identity=29.3172690763052, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790011, Length=312, Percent_Identity=25, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788748, Length=235, Percent_Identity=32.3404255319149, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI157672245, Length=143, Percent_Identity=32.8671328671329, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787601, Length=181, Percent_Identity=24.8618784530387, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082132, Length=175, Percent_Identity=30.2857142857143, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790783, Length=294, Percent_Identity=26.1904761904762, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI145693105, Length=117, Percent_Identity=32.4786324786325, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33443; Mature: 33312

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLPFDVHRLLPAFLAAAQAQNFSAAARQLGVTPAAISKNIRVLEEKLALRLFQRNTHNV
CCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
VLTDEGKALLQQVAPLWQALSATLETAGSAQQAPSGTVRVSMIPGFGRQMLMPLIPQFLE
EEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
RYPQIDLDLSLDARVVNLVGEGFDVGIGSRVDPDSRLVARSLYPMQMVLAASPGYLAQHG
HCCCCCEECCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCHHHHCC
IPQDPQDLLQHNCLLHRNPATGRSVKWPLQQQGEAKALELQGRLVASRPEMLLDAALAGL
CCCCHHHHHHCCCEEECCCCCCCCEECCHHHCCCCCEEHHCCCHHHCCHHHHHHHHHHHH
GIVCLARWYAEHHFAQGTLQPVLADCWPRPTQLWLYYASADLPPRVRVWVEFLLEHFRHR
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCC
PA
CC
>Mature Secondary Structure 
SLPFDVHRLLPAFLAAAQAQNFSAAARQLGVTPAAISKNIRVLEEKLALRLFQRNTHNV
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCEE
VLTDEGKALLQQVAPLWQALSATLETAGSAQQAPSGTVRVSMIPGFGRQMLMPLIPQFLE
EEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
RYPQIDLDLSLDARVVNLVGEGFDVGIGSRVDPDSRLVARSLYPMQMVLAASPGYLAQHG
HCCCCCEECCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHHCCCCHHHHCC
IPQDPQDLLQHNCLLHRNPATGRSVKWPLQQQGEAKALELQGRLVASRPEMLLDAALAGL
CCCCHHHHHHCCCEEECCCCCCCCEECCHHHCCCCCEEHHCCCHHHCCHHHHHHHHHHHH
GIVCLARWYAEHHFAQGTLQPVLADCWPRPTQLWLYYASADLPPRVRVWVEFLLEHFRHR
HHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHCC
PA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8748036 [H]