Click here to switch to the map view.

The map label for this gene is treB [H]

Identifier: 157368776

GI number: 157368776

Start: 581942

End: 583357

Strand: Reverse

Name: treB [H]

Synonym: Spro_0529

Alternate gene names: 157368776

Gene position: 583357-581942 (Counterclockwise)

Preceding gene: 157368778

Following gene: 157368775

Centisome position: 10.71

GC content: 59.18

Gene sequence:

>1416_bases
ATGAGCAAAGTAAAACAGCAGGATATCGATCGCCTGATTGTGCTGGTGGGCGGGCGCGAGAATATCGCTACCGTTAGCCA
CTGCATTACCAGGCTGCGTTTTGTTCTCAATGACCCAGCTCTGGCCAAACCGAAAGAAATCGAAGAGTTGCCGATGGTCA
AAGGCTGCTTCACCAATGCCGGGCAGTTCCAGGTGGTGATCGGCCCCGAGGTCGGGGATTACTACCAGGCTCTGATCGCC
ACCACCGGCGTCAATGAAGCCGACAAAGAGCAGGCCAAGGTCGCAGCGCGCCAGAACATGACCTGGAGCGAACGCGCCAT
CTCGCACTTCGCCGAAATCTTCTTCCCGCTGCTGCCTGCCTTGATCAGCGGCGGTTTGATCCTCGGTTTCCGCAACGTCA
TCGGCGACATCCCGATGTCCGGCGGCCAAACGCTGGCGCAGATGCACCCGGCGTGGAAAACCATCTACGACTTCCTGTGG
TTGCTCGGTGAAGCCATCTTCATGTTCCTGCCGGTCGCCATTTGCTGGTCAACGGTGAAAAAAATGGGCGGTACGCCGGT
ACTCGGCATCGTGCTGGGTATCACGCTGGTGTCCCCGCAGTTGATGAACTCCTATCAGCTCGGCCAGCAGATCCCGGAAG
TGTGGAACTTCGGCTGGTTCACCATTCAGAAAGTCGGCTATCAGGCGCAGGTGATCCCTTCCATGCTGGCCGGTATGGCG
CTGGGCTGGATTGAGACCCGCTTGAAAAAGATCGTGCCGGATTACCTGTATCTGGTGGTGGTGCCGGTGGTTTCCCTGCT
GCTGGCGGTGTTCCTGGCGCACGCATTTATCGGGCCGTTCGGCCGCATGATTGGCGACGGGGTAGCCTGGGCGGTGAAAG
CCGTGATGACCGGCAGCTTCGCACCTATTGGTGCCGCGCTGTTTGGCTTCCTGTATGCACCGCTGGTGATTACCGGCGTG
CATCAGACCACGCTGGCCATCGATATGCAGATGATCCAGAGCATGGGCGGCACCCCGGTTTGGCCACTGATCGCACTGTC
CAACATTGCGCAGGCCTCGGCGGTGCTGGGCATTATTATTGTCAGCCGCAAGGCCAACGAACGTGAAATCTCGGTGCCGG
CGGCCATCTCCGCCTACCTCGGCGTCACCGAACCGGCGATGTACGGGATCAACCTGAAATACCGTTTCCCAATGCTGTGC
GCAATGATTGGCTCCGCCTTCGCCGGGCTGATCTGCGGCCTGGACGGCGTGATGGCTAACGGTATCGGCGTCGGTGGTTT
GCCGGGCATTCTGTCGATCAAACCGCAGTTCTGGATGATTTACACGGTGGCGATCCTGGTGGCGGTGGTGATCCCACTGG
TACTGACCATCATGGTTTACAAACGCAAGGCCAGCCGCGGTGAGCTGCCGGTCTGA

Upstream 100 bases:

>100_bases
GGAACGTTCCCATTCCATAAAAAAAGCGGAGTGACTAAGCTTTGATCATTACTCCGACAACACCTCTGCGGCAGTCCCAT
ACCAAGAAAGGTATCTAATA

Downstream 100 bases:

>100_bases
TTGAAATGTAGGGGCCCGGTACGCCGGGTCTATTAAGGTATTTATATGAGCAATCCAATCCCCTGGTGGCAGAACGGCGT
CATCTATCAAATCTATCCGA

Product: PTS system trehalose(maltose)-specific transporter subunits IIBC

Products: NA

Alternate protein names: EIIBC-Tre; EII-Tre; Trehalose-specific phosphotransferase enzyme IIB component; PTS system trehalose-specific EIIB component; Trehalose permease IIC component; PTS system trehalose-specific EIIC component [H]

Number of amino acids: Translated: 471; Mature: 470

Protein sequence:

>471_residues
MSKVKQQDIDRLIVLVGGRENIATVSHCITRLRFVLNDPALAKPKEIEELPMVKGCFTNAGQFQVVIGPEVGDYYQALIA
TTGVNEADKEQAKVAARQNMTWSERAISHFAEIFFPLLPALISGGLILGFRNVIGDIPMSGGQTLAQMHPAWKTIYDFLW
LLGEAIFMFLPVAICWSTVKKMGGTPVLGIVLGITLVSPQLMNSYQLGQQIPEVWNFGWFTIQKVGYQAQVIPSMLAGMA
LGWIETRLKKIVPDYLYLVVVPVVSLLLAVFLAHAFIGPFGRMIGDGVAWAVKAVMTGSFAPIGAALFGFLYAPLVITGV
HQTTLAIDMQMIQSMGGTPVWPLIALSNIAQASAVLGIIIVSRKANEREISVPAAISAYLGVTEPAMYGINLKYRFPMLC
AMIGSAFAGLICGLDGVMANGIGVGGLPGILSIKPQFWMIYTVAILVAVVIPLVLTIMVYKRKASRGELPV

Sequences:

>Translated_471_residues
MSKVKQQDIDRLIVLVGGRENIATVSHCITRLRFVLNDPALAKPKEIEELPMVKGCFTNAGQFQVVIGPEVGDYYQALIA
TTGVNEADKEQAKVAARQNMTWSERAISHFAEIFFPLLPALISGGLILGFRNVIGDIPMSGGQTLAQMHPAWKTIYDFLW
LLGEAIFMFLPVAICWSTVKKMGGTPVLGIVLGITLVSPQLMNSYQLGQQIPEVWNFGWFTIQKVGYQAQVIPSMLAGMA
LGWIETRLKKIVPDYLYLVVVPVVSLLLAVFLAHAFIGPFGRMIGDGVAWAVKAVMTGSFAPIGAALFGFLYAPLVITGV
HQTTLAIDMQMIQSMGGTPVWPLIALSNIAQASAVLGIIIVSRKANEREISVPAAISAYLGVTEPAMYGINLKYRFPMLC
AMIGSAFAGLICGLDGVMANGIGVGGLPGILSIKPQFWMIYTVAILVAVVIPLVLTIMVYKRKASRGELPV
>Mature_470_residues
SKVKQQDIDRLIVLVGGRENIATVSHCITRLRFVLNDPALAKPKEIEELPMVKGCFTNAGQFQVVIGPEVGDYYQALIAT
TGVNEADKEQAKVAARQNMTWSERAISHFAEIFFPLLPALISGGLILGFRNVIGDIPMSGGQTLAQMHPAWKTIYDFLWL
LGEAIFMFLPVAICWSTVKKMGGTPVLGIVLGITLVSPQLMNSYQLGQQIPEVWNFGWFTIQKVGYQAQVIPSMLAGMAL
GWIETRLKKIVPDYLYLVVVPVVSLLLAVFLAHAFIGPFGRMIGDGVAWAVKAVMTGSFAPIGAALFGFLYAPLVITGVH
QTTLAIDMQMIQSMGGTPVWPLIALSNIAQASAVLGIIIVSRKANEREISVPAAISAYLGVTEPAMYGINLKYRFPMLCA
MIGSAFAGLICGLDGVMANGIGVGGLPGILSIKPQFWMIYTVAILVAVVIPLVLTIMVYKRKASRGELPV

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=471, Percent_Identity=80.8917197452229, Blast_Score=771, Evalue=0.0,
Organism=Escherichia coli, GI1790159, Length=471, Percent_Identity=25.9023354564756, Blast_Score=159, Evalue=5e-40,
Organism=Escherichia coli, GI1788769, Length=429, Percent_Identity=26.8065268065268, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI48994906, Length=424, Percent_Identity=26.4150943396226, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR011296 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 50912; Mature: 50781

Theoretical pI: Translated: 9.04; Mature: 9.04

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKVKQQDIDRLIVLVGGRENIATVSHCITRLRFVLNDPALAKPKEIEELPMVKGCFTNA
CCCCHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHCCCC
GQFQVVIGPEVGDYYQALIATTGVNEADKEQAKVAARQNMTWSERAISHFAEIFFPLLPA
CCEEEEECCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
LISGGLILGFRNVIGDIPMSGGQTLAQMHPAWKTIYDFLWLLGEAIFMFLPVAICWSTVK
HHCCCHHHHHHHHHCCCCCCCCCHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KMGGTPVLGIVLGITLVSPQLMNSYQLGQQIPEVWNFGWFTIQKVGYQAQVIPSMLAGMA
HCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHH
LGWIETRLKKIVPDYLYLVVVPVVSLLLAVFLAHAFIGPFGRMIGDGVAWAVKAVMTGSF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APIGAALFGFLYAPLVITGVHQTTLAIDMQMIQSMGGTPVWPLIALSNIAQASAVLGIII
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHE
VSRKANEREISVPAAISAYLGVTEPAMYGINLKYRFPMLCAMIGSAFAGLICGLDGVMAN
EECCCCCCCCCCHHHHHHHHCCCCCHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHC
GIGVGGLPGILSIKPQFWMIYTVAILVAVVIPLVLTIMVYKRKASRGELPV
CCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SKVKQQDIDRLIVLVGGRENIATVSHCITRLRFVLNDPALAKPKEIEELPMVKGCFTNA
CCCHHHHHCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHCCCC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CCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7608078; 7610040; 9278503 [H]