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The map label for this gene is orn

Identifier: 157368671

GI number: 157368671

Start: 473893

End: 474438

Strand: Direct

Name: orn

Synonym: Spro_0424

Alternate gene names: 157368671

Gene position: 473893-474438 (Clockwise)

Preceding gene: 157368667

Following gene: 157368673

Centisome position: 8.7

GC content: 54.76

Gene sequence:

>546_bases
ATGACAGGAAACGAAAATAACCTGATTTGGATCGATCTGGAGATGACCGGGTTGGATCCAGAACGCGATCGCATTATCGA
GATCGCCACCCTGGTCACCGACGCCAATCTGAATATCCTCGCGGAAGGGCCAGTGATCGCCGTGCATCAATCAGACGAAC
AGCTTGGCCTGATGGATGACTGGAACGTGCGGACTCATACCGGCAGCGGGCTGGTGGAAAGGGTGAAGGCCAGTCAGTAC
GACGACCATGCCGCCGAGTTGGCCACTATCGCCTTTTTGCAACAGTGGGTACCGGCGGGCAAATCACCAATCTGCGGCAA
CAGTGTGGGCCAGGACCGCCGCTTCCTGTTCCGCTATATGCCGGAACTGGAAGCCTACTTCCATTACCGCTATCTGGATG
TCAGCACTTTGAAGGAGCTGGCGCGCCGTTGGAAACCGGAAATCCTCAGCGGTTTTAAAAAGCAGGGGACTCATCAGGCT
ATGGATGATATCCGTGAGTCAGTGGGCGAATTGGCCTACTACCGTGAGCATTTCATCCAGCTATAA

Upstream 100 bases:

>100_bases
TAGCCGCCACGTGCAGCCTACTACCGTCGGCAAACAGCCAGCGTCGCTCGCCGCCTTGCCTATAGTTTGTTTATCTTTTG
GCTTTTACGCAGGAAATATC

Downstream 100 bases:

>100_bases
TGGATGTCAGGCCCCTGAACAGGGGGCCTAATTACTGCAAGCGGCCAATTCCGCCGCTTAATTAACCAGTTTGGCGCTTT
AATCGGCAAACAAACAAAAA

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MTGNENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVIAVHQSDEQLGLMDDWNVRTHTGSGLVERVKASQY
DDHAAELATIAFLQQWVPAGKSPICGNSVGQDRRFLFRYMPELEAYFHYRYLDVSTLKELARRWKPEILSGFKKQGTHQA
MDDIRESVGELAYYREHFIQL

Sequences:

>Translated_181_residues
MTGNENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVIAVHQSDEQLGLMDDWNVRTHTGSGLVERVKASQY
DDHAAELATIAFLQQWVPAGKSPICGNSVGQDRRFLFRYMPELEAYFHYRYLDVSTLKELARRWKPEILSGFKKQGTHQA
MDDIRESVGELAYYREHFIQL
>Mature_180_residues
TGNENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVIAVHQSDEQLGLMDDWNVRTHTGSGLVERVKASQYD
DHAAELATIAFLQQWVPAGKSPICGNSVGQDRRFLFRYMPELEAYFHYRYLDVSTLKELARRWKPEILSGFKKQGTHQAM
DDIRESVGELAYYREHFIQL

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=173, Percent_Identity=49.1329479768786, Blast_Score=177, Evalue=5e-45,
Organism=Escherichia coli, GI87082382, Length=181, Percent_Identity=89.5027624309392, Blast_Score=344, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17557752, Length=172, Percent_Identity=49.4186046511628, Blast_Score=166, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6323088, Length=187, Percent_Identity=34.7593582887701, Blast_Score=115, Evalue=5e-27,
Organism=Drosophila melanogaster, GI21355135, Length=180, Percent_Identity=44.4444444444444, Blast_Score=181, Evalue=2e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_SERP5 (A8G8U2)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476660.1
- ProteinModelPortal:   A8G8U2
- SMR:   A8G8U2
- STRING:   A8G8U2
- GeneID:   5602465
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0424
- eggNOG:   COG1949
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- ProtClustDB:   PRK05359
- BioCyc:   SPRO399741:SPRO_0424-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 20767; Mature: 20636

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGNENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVIAVHQSDEQLGLMDD
CCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCCCCCC
WNVRTHTGSGLVERVKASQYDDHAAELATIAFLQQWVPAGKSPICGNSVGQDRRFLFRYM
CCCEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
PELEAYFHYRYLDVSTLKELARRWKPEILSGFKKQGTHQAMDDIRESVGELAYYREHFIQ
HHHHHHHHHHEECHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure 
TGNENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGPVIAVHQSDEQLGLMDD
CCCCCCEEEEEEEEECCCCCHHHHHHHHHHHCCCCCEEEECCCEEEEECCCCCCCCCCC
WNVRTHTGSGLVERVKASQYDDHAAELATIAFLQQWVPAGKSPICGNSVGQDRRFLFRYM
CCCEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
PELEAYFHYRYLDVSTLKELARRWKPEILSGFKKQGTHQAMDDIRESVGELAYYREHFIQ
HHHHHHHHHHEECHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA