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The map label for this gene is grsT [H]

Identifier: 157368592

GI number: 157368592

Start: 394655

End: 395380

Strand: Direct

Name: grsT [H]

Synonym: Spro_0343

Alternate gene names: 157368592

Gene position: 394655-395380 (Clockwise)

Preceding gene: 157368591

Following gene: 157368593

Centisome position: 7.24

GC content: 57.44

Gene sequence:

>726_bases
ATGTGCCTGATCTTTTGTCTGCCGCATGCCGGCGGCGGAGCTCATCACTATTTTGGCTGGGCGGCGCACCTTGCCCCTGA
CATTCAATGGGAGCCGCTTGATTATGCCGGGCACTTTTCCCGCATGGATGAGCCGGCGTATGCCTCGTTCGAACAGGCGG
TTGAGGATCTGGCGGAGGTCATGATCGCCCGTGCCAGCGGGCACCCATTCGCCCTGTTTGGCCACAGTATGGGGGGCGCG
CTGGCTTATGAAATTGCTCAGTACCTGGCTGCACGGCAATTGGCGAAAGATCTGTCGTTCATTGCTGTCTCCAGCGCGCT
GCCGCCGCACCGCCGCGACCCGAATATGCCACGTTATTACGAACTGCCCGATTGGGATTTTATTCAGCACCTGATCGACA
CCGGCGGGATGACGGCGCAATTGGCCGCGCAGGCTGAATTGATGGCGAGCTATTTGCCATTAATTCGGCAGGATTATCAG
CTTTATCATCAATATCAGCCGCCTTCGCATCCGCCGTTGTCCACCCCGCTGTATGCCTTGTGGGGGGAAGAGGAGGAGGA
TCGCAATGACAACATGCCGGCCTGGGCGGATTACAGTCACGCTTTTAATGGGAGCAAGGCTTATCCCGGCGATCATTTCT
TTTGGCGTCATTGTCTGGGCGCCGTTGCTGCCGATATTTCGGCTATCGCTAGCCAAGCGTCCACCGGTCAAACCTGCAGA
CGTTAA

Upstream 100 bases:

>100_bases
CACCACACGAGGTGGGGTTGGGGGACATTTTCAAATATCCGACGATTCGCAAAATGGCCGCTTGGTTGGATGAGTCCTCC
GTGCATGCGGAGGGCGAATA

Downstream 100 bases:

>100_bases
CTTTCTATCAGGAATAGCACTATGCCGATTTTGAACAACAAAGAAGTCATCGTGATTATTGACGCCTGGTCTGGCGGCAA
ATATTTGATCCCTGCATTTC

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MCLIFCLPHAGGGAHHYFGWAAHLAPDIQWEPLDYAGHFSRMDEPAYASFEQAVEDLAEVMIARASGHPFALFGHSMGGA
LAYEIAQYLAARQLAKDLSFIAVSSALPPHRRDPNMPRYYELPDWDFIQHLIDTGGMTAQLAAQAELMASYLPLIRQDYQ
LYHQYQPPSHPPLSTPLYALWGEEEEDRNDNMPAWADYSHAFNGSKAYPGDHFFWRHCLGAVAADISAIASQASTGQTCR
R

Sequences:

>Translated_241_residues
MCLIFCLPHAGGGAHHYFGWAAHLAPDIQWEPLDYAGHFSRMDEPAYASFEQAVEDLAEVMIARASGHPFALFGHSMGGA
LAYEIAQYLAARQLAKDLSFIAVSSALPPHRRDPNMPRYYELPDWDFIQHLIDTGGMTAQLAAQAELMASYLPLIRQDYQ
LYHQYQPPSHPPLSTPLYALWGEEEEDRNDNMPAWADYSHAFNGSKAYPGDHFFWRHCLGAVAADISAIASQASTGQTCR
R
>Mature_241_residues
MCLIFCLPHAGGGAHHYFGWAAHLAPDIQWEPLDYAGHFSRMDEPAYASFEQAVEDLAEVMIARASGHPFALFGHSMGGA
LAYEIAQYLAARQLAKDLSFIAVSSALPPHRRDPNMPRYYELPDWDFIQHLIDTGGMTAQLAAQAELMASYLPLIRQDYQ
LYHQYQPPSHPPLSTPLYALWGEEEEDRNDNMPAWADYSHAFNGSKAYPGDHFFWRHCLGAVAADISAIASQASTGQTCR
R

Specific function: Probable thioesterase involved in the biosynthesis of gramicidin S [H]

COG id: COG3208

COG function: function code Q; Predicted thioesterase involved in non-ribosomal peptide biosynthesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioesterase family [H]

Homologues:

Organism=Homo sapiens, GI89257335, Length=214, Percent_Identity=28.5046728971963, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI8922871, Length=185, Percent_Identity=29.1891891891892, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012223
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00975 Thioesterase [H]

EC number: NA

Molecular weight: Translated: 26913; Mature: 26913

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCLIFCLPHAGGGAHHYFGWAAHLAPDIQWEPLDYAGHFSRMDEPAYASFEQAVEDLAEV
CEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
MIARASGHPFALFGHSMGGALAYEIAQYLAARQLAKDLSFIAVSSALPPHRRDPNMPRYY
HHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
ELPDWDFIQHLIDTGGMTAQLAAQAELMASYLPLIRQDYQLYHQYQPPSHPPLSTPLYAL
ECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
WGEEEEDRNDNMPAWADYSHAFNGSKAYPGDHFFWRHCLGAVAADISAIASQASTGQTCR
CCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCC
R
C
>Mature Secondary Structure
MCLIFCLPHAGGGAHHYFGWAAHLAPDIQWEPLDYAGHFSRMDEPAYASFEQAVEDLAEV
CEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHH
MIARASGHPFALFGHSMGGALAYEIAQYLAARQLAKDLSFIAVSSALPPHRRDPNMPRYY
HHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEE
ELPDWDFIQHLIDTGGMTAQLAAQAELMASYLPLIRQDYQLYHQYQPPSHPPLSTPLYAL
ECCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEE
WGEEEEDRNDNMPAWADYSHAFNGSKAYPGDHFFWRHCLGAVAADISAIASQASTGQTCR
CCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2477357; 7512553 [H]