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The map label for this gene is argH2 [H]

Identifier: 157368593

GI number: 157368593

Start: 395402

End: 396676

Strand: Direct

Name: argH2 [H]

Synonym: Spro_0344

Alternate gene names: 157368593

Gene position: 395402-396676 (Clockwise)

Preceding gene: 157368592

Following gene: 157368594

Centisome position: 7.26

GC content: 56.08

Gene sequence:

>1275_bases
ATGCCGATTTTGAACAACAAAGAAGTCATCGTGATTATTGACGCCTGGTCTGGCGGCAAATATTTGATCCCTGCATTTCA
GGCGCTCGGGTATTTTTGCCTGCACGTCCAATCCCCGTTTCTACCGGCGGTCTTCGTTGCGGATAACCAACTGGCCATTG
CCCGCAGCGACAGGCATGTCGTTCATGATGGCGATATTGAGACGCTGCTCAACGCGCTACAACCTTATGCCATCAAGGCA
ATACTTGCTGGCAGCGAGGGCGCGGTTGCACTGGCCGATCGCTTGAATGATGCTCTGGCGCTTGCCTTTAGCAATCGGTT
CGAACTCTCCGCGGCGCGGCGTAATAAATTCCTGATGCAGGAACAGCTTGCCCGCAGGGGTGTGGCGTCCATCAAGCAGC
GGCTGACTGCTGACTGTGATGAATTACAGCAGTGGCTGGCGAGCCACGATCGCTGGCCGGTGGTGCTGAAACCGGTGCAA
AGCGCCGGTACCGACGGGGTATTTATCTGCCATGACCTGGCGCAGGCCACCCAGGCGTTTGACGCTATTCTGGCGAAAAA
AGATCTCTTCGGCAGCCCTAACCGGGAAGTGCTGTGCCAGGAGTTTTTGGTGGGCGAAGAGTTTGTGGTCAACGGCATTG
CCTGCCAGGGAGAGTATTTCTTTACCGAGTTGTGGCAGTCCAAAAAGCAACAGCGCAACGGTTTTCCTGTGTATGAAACG
CAATATCTGCACTATCGGAATGACGCCGGCTTCGATGTATTGGCCGCCTATACCGCGCAAGTGTGCCAGGCGCTTGGCAT
CGAGAACGGGGCCTTTCATGCCGAGGTGATGATGACGCAGAGCGGGCCTGTGTTGATTGAAATCGGCGCCCGGGTCGCCG
GCGGTGCGGACCCTTATATTATCGAAGAGTGTCTGGGGCATTCGCAGATAGGCAAATTGGTGCAGGCGGTCCTGCACCCT
GAGGTGTTCCTGCAGGAAGTTCGGCGGCAGCGCGATTTTTCCGGCCATCGGCGCGCCGCCTATGTTTTCATGATTTCGCC
CTCCACGGGCCGGGTGCAAAGCTCGCCGGAAGCGCGATTTATCTCTATCGACGGTGTTATCAGCGTCAATTATCACCACA
TGCCCGGCGATATTCAGCAAGAGACCCGCGACCTGCTGAGCTCCCCAGGGGTGGTTATTGCCATCCGAGATAACCCTGCC
TTGCTAAAGCAGACGATTGCGGAGATCCGAGATGTCGAAGGCGATTTTTACCACTCGGGTCTGATGGCTGAATAA

Upstream 100 bases:

>100_bases
TCATTGTCTGGGCGCCGTTGCTGCCGATATTTCGGCTATCGCTAGCCAAGCGTCCACCGGTCAAACCTGCAGACGTTAAC
TTTCTATCAGGAATAGCACT

Downstream 100 bases:

>100_bases
GGGAAACGACATGAATTTGGAACTATGGGTAAAAAACATTGGCACCACATTCCCCTGGTATGCGCAATTGCTCGGCGATA
AGCCGGCGGACGCCAGCCGT

Product: phosphoribosylglycinamide synthetase

Products: NA

Alternate protein names: ASAL 2; Arginosuccinase 2 [H]

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MPILNNKEVIVIIDAWSGGKYLIPAFQALGYFCLHVQSPFLPAVFVADNQLAIARSDRHVVHDGDIETLLNALQPYAIKA
ILAGSEGAVALADRLNDALALAFSNRFELSAARRNKFLMQEQLARRGVASIKQRLTADCDELQQWLASHDRWPVVLKPVQ
SAGTDGVFICHDLAQATQAFDAILAKKDLFGSPNREVLCQEFLVGEEFVVNGIACQGEYFFTELWQSKKQQRNGFPVYET
QYLHYRNDAGFDVLAAYTAQVCQALGIENGAFHAEVMMTQSGPVLIEIGARVAGGADPYIIEECLGHSQIGKLVQAVLHP
EVFLQEVRRQRDFSGHRRAAYVFMISPSTGRVQSSPEARFISIDGVISVNYHHMPGDIQQETRDLLSSPGVVIAIRDNPA
LLKQTIAEIRDVEGDFYHSGLMAE

Sequences:

>Translated_424_residues
MPILNNKEVIVIIDAWSGGKYLIPAFQALGYFCLHVQSPFLPAVFVADNQLAIARSDRHVVHDGDIETLLNALQPYAIKA
ILAGSEGAVALADRLNDALALAFSNRFELSAARRNKFLMQEQLARRGVASIKQRLTADCDELQQWLASHDRWPVVLKPVQ
SAGTDGVFICHDLAQATQAFDAILAKKDLFGSPNREVLCQEFLVGEEFVVNGIACQGEYFFTELWQSKKQQRNGFPVYET
QYLHYRNDAGFDVLAAYTAQVCQALGIENGAFHAEVMMTQSGPVLIEIGARVAGGADPYIIEECLGHSQIGKLVQAVLHP
EVFLQEVRRQRDFSGHRRAAYVFMISPSTGRVQSSPEARFISIDGVISVNYHHMPGDIQQETRDLLSSPGVVIAIRDNPA
LLKQTIAEIRDVEGDFYHSGLMAE
>Mature_423_residues
PILNNKEVIVIIDAWSGGKYLIPAFQALGYFCLHVQSPFLPAVFVADNQLAIARSDRHVVHDGDIETLLNALQPYAIKAI
LAGSEGAVALADRLNDALALAFSNRFELSAARRNKFLMQEQLARRGVASIKQRLTADCDELQQWLASHDRWPVVLKPVQS
AGTDGVFICHDLAQATQAFDAILAKKDLFGSPNREVLCQEFLVGEEFVVNGIACQGEYFFTELWQSKKQQRNGFPVYETQ
YLHYRNDAGFDVLAAYTAQVCQALGIENGAFHAEVMMTQSGPVLIEIGARVAGGADPYIIEECLGHSQIGKLVQAVLHPE
VFLQEVRRQRDFSGHRRAAYVFMISPSTGRVQSSPEARFISIDGVISVNYHHMPGDIQQETRDLLSSPGVVIAIRDNPAL
LKQTIAEIRDVEGDFYHSGLMAE

Specific function: Unknown

COG id: COG0439

COG function: function code I; Biotin carboxylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009049
- InterPro:   IPR011761
- InterPro:   IPR003806
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005479
- InterPro:   IPR003031
- InterPro:   IPR000362
- InterPro:   IPR008948
- InterPro:   IPR022761 [H]

Pfam domain/function: PF02655 ATP-grasp_3; PF00206 Lyase_1 [H]

EC number: =4.3.2.1 [H]

Molecular weight: Translated: 46927; Mature: 46796

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPILNNKEVIVIIDAWSGGKYLIPAFQALGYFCLHVQSPFLPAVFVADNQLAIARSDRHV
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCCCEEEEECCEEEEEECCCCE
VHDGDIETLLNALQPYAIKAILAGSEGAVALADRLNDALALAFSNRFELSAARRNKFLMQ
EECCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHCHHEEEEECCCEEEHHHHHHHHHHH
EQLARRGVASIKQRLTADCDELQQWLASHDRWPVVLKPVQSAGTDGVFICHDLAQATQAF
HHHHHCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEHHCCCCCCEEEHHHHHHHHHHH
DAILAKKDLFGSPNREVLCQEFLVGEEFVVNGIACQGEYFFTELWQSKKQQRNGFPVYET
HHHHHHHHCCCCCCHHHHHHHHHCCCHHHEECEEECCHHHHHHHHHHHHHHCCCCCEEEE
QYLHYRNDAGFDVLAAYTAQVCQALGIENGAFHAEVMMTQSGPVLIEIGARVAGGADPYI
EEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEECCEECCCCCHHH
IEECLGHSQIGKLVQAVLHPEVFLQEVRRQRDFSGHRRAAYVFMISPSTGRVQSSPEARF
HHHHCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCEE
ISIDGVISVNYHHMPGDIQQETRDLLSSPGVVIAIRDNPALLKQTIAEIRDVEGDFYHSG
EEECCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHCCC
LMAE
CCCC
>Mature Secondary Structure 
PILNNKEVIVIIDAWSGGKYLIPAFQALGYFCLHVQSPFLPAVFVADNQLAIARSDRHV
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHEEECCCCCCEEEEECCEEEEEECCCCE
VHDGDIETLLNALQPYAIKAILAGSEGAVALADRLNDALALAFSNRFELSAARRNKFLMQ
EECCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHCHHEEEEECCCEEEHHHHHHHHHHH
EQLARRGVASIKQRLTADCDELQQWLASHDRWPVVLKPVQSAGTDGVFICHDLAQATQAF
HHHHHCCHHHHHHHHCCCHHHHHHHHHCCCCCCEEEEEHHCCCCCCEEEHHHHHHHHHHH
DAILAKKDLFGSPNREVLCQEFLVGEEFVVNGIACQGEYFFTELWQSKKQQRNGFPVYET
HHHHHHHHCCCCCCHHHHHHHHHCCCHHHEECEEECCHHHHHHHHHHHHHHCCCCCEEEE
QYLHYRNDAGFDVLAAYTAQVCQALGIENGAFHAEVMMTQSGPVLIEIGARVAGGADPYI
EEEEECCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCEEEEECCEECCCCCHHH
IEECLGHSQIGKLVQAVLHPEVFLQEVRRQRDFSGHRRAAYVFMISPSTGRVQSSPEARF
HHHHCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCCCCCCEE
ISIDGVISVNYHHMPGDIQQETRDLLSSPGVVIAIRDNPALLKQTIAEIRDVEGDFYHSG
EEECCEEEEEEECCCCCHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCHHCCC
LMAE
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]