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The map label for this gene is pheA [H]

Identifier: 154246570

GI number: 154246570

Start: 2917575

End: 2918435

Strand: Reverse

Name: pheA [H]

Synonym: Xaut_2629

Alternate gene names: 154246570

Gene position: 2918435-2917575 (Counterclockwise)

Preceding gene: 154246571

Following gene: 154246566

Centisome position: 54.97

GC content: 67.6

Gene sequence:

>861_bases
ATGATCCGCCGCATCACCTTCCAGGGCGAGCCGGGCGCCAATTCGCACATCGCCTGCCGCGAGGTGTTTCCGGATTTCGA
GGCGGTGCCCTGCGCCACCTTCGAGGACGCCTTCGCCGGGGTCGAGAGCGGCGCGGCCACCTATGCCATGATTCCCATCG
AGAATTCGGTGGCGGGCCGGGTTGCGGACATCCACCACCTGATGCCCCAGTCGTCGCTCTCGATCATCGGCGAGCACTTC
CTGCCGCTGTCGCACCAGCTCATGGCGGTGAAGGGGGCGAGCCTCTCCACCCTGAAGAGCGTGCAGAGCCACGTGATGGC
GCTGGGCCAGTGCCGCAAGGCCATCCGCACCCTCAACCTGACCGCCGTCATCGGCGCCGATACCGCAGGCTCCGCCCGCG
AGATCGCGGAAGCCGGCGACGTGAGCCGCGCCGCCATCGCCTCGCGCCTCGCGGCCGACATCTACGGGCTCGACATCCTC
GCCGAGAACATCGAGGACGAGGCCCACAACACCACGCGCTTCATCATCCTGTCGCGCGGCGGAGAATGGACGCCGGCGGG
CAATGGGCCGGTGGTCACCACCTTCGTATTCCGGGTGCGCAACGTGCCGGCGGCGCTCTACAAGGCGCTGGGGGGCTTTG
CCACCAACGGGGTGAACATGACCAAGCTGGAATCCTACCAGCTCGACGGCCGCTTCACCGCCACCCAGTTCTATGCCGAC
GTGGACGGCCACCCGGACGACCGGCCGGTGAAGCTGGCGCTAGAGGAGCTCGCCTTCTTCTCCCGCGAGATGCGCATTCT
CGGCGTCTATCCCGCCCATCCCTACCGGGCGCAGTTCGCGGCGGAGCAGGAAACGTTCTGA

Upstream 100 bases:

>100_bases
GTGGTGGACGCGGTGCCGCTGGGGGTGGACACACAGGCCCATCTCGACCGCGCCCGCGCGATTCTCGCGCTCGAAGCCGC
CGAACAAAAATGAGGACATC

Downstream 100 bases:

>100_bases
GGAGACGGTCTGATCCGGACGTTCTGAACGGGCGGAGCGCCGCTCCGTTCAGTGATCAAAGCTCAGGGCGATGCGCGCCT
TGCCGCCGCCGGTGCGGCCG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MIRRITFQGEPGANSHIACREVFPDFEAVPCATFEDAFAGVESGAATYAMIPIENSVAGRVADIHHLMPQSSLSIIGEHF
LPLSHQLMAVKGASLSTLKSVQSHVMALGQCRKAIRTLNLTAVIGADTAGSAREIAEAGDVSRAAIASRLAADIYGLDIL
AENIEDEAHNTTRFIILSRGGEWTPAGNGPVVTTFVFRVRNVPAALYKALGGFATNGVNMTKLESYQLDGRFTATQFYAD
VDGHPDDRPVKLALEELAFFSREMRILGVYPAHPYRAQFAAEQETF

Sequences:

>Translated_286_residues
MIRRITFQGEPGANSHIACREVFPDFEAVPCATFEDAFAGVESGAATYAMIPIENSVAGRVADIHHLMPQSSLSIIGEHF
LPLSHQLMAVKGASLSTLKSVQSHVMALGQCRKAIRTLNLTAVIGADTAGSAREIAEAGDVSRAAIASRLAADIYGLDIL
AENIEDEAHNTTRFIILSRGGEWTPAGNGPVVTTFVFRVRNVPAALYKALGGFATNGVNMTKLESYQLDGRFTATQFYAD
VDGHPDDRPVKLALEELAFFSREMRILGVYPAHPYRAQFAAEQETF
>Mature_286_residues
MIRRITFQGEPGANSHIACREVFPDFEAVPCATFEDAFAGVESGAATYAMIPIENSVAGRVADIHHLMPQSSLSIIGEHF
LPLSHQLMAVKGASLSTLKSVQSHVMALGQCRKAIRTLNLTAVIGADTAGSAREIAEAGDVSRAAIASRLAADIYGLDIL
AENIEDEAHNTTRFIILSRGGEWTPAGNGPVVTTFVFRVRNVPAALYKALGGFATNGVNMTKLESYQLDGRFTATQFYAD
VDGHPDDRPVKLALEELAFFSREMRILGVYPAHPYRAQFAAEQETF

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=275, Percent_Identity=33.8181818181818, Blast_Score=147, Evalue=7e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 30914; Mature: 30914

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00857 PREPHENATE_DEHYDR_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRITFQGEPGANSHIACREVFPDFEAVPCATFEDAFAGVESGAATYAMIPIENSVAGR
CCEEEEECCCCCCCCCEEHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHH
VADIHHLMPQSSLSIIGEHFLPLSHQLMAVKGASLSTLKSVQSHVMALGQCRKAIRTLNL
HHHHHHHCCCHHHHHHHHHCCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCE
TAVIGADTAGSAREIAEAGDVSRAAIASRLAADIYGLDILAENIEDEAHNTTRFIILSRG
EEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GEWTPAGNGPVVTTFVFRVRNVPAALYKALGGFATNGVNMTKLESYQLDGRFTATQFYAD
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCHHCCCCCEEEEEEEEECCEEEEEEEEEE
VDGHPDDRPVKLALEELAFFSREMRILGVYPAHPYRAQFAAEQETF
CCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHCCCCCCC
>Mature Secondary Structure
MIRRITFQGEPGANSHIACREVFPDFEAVPCATFEDAFAGVESGAATYAMIPIENSVAGR
CCEEEEECCCCCCCCCEEHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEEEECCCCCHH
VADIHHLMPQSSLSIIGEHFLPLSHQLMAVKGASLSTLKSVQSHVMALGQCRKAIRTLNL
HHHHHHHCCCHHHHHHHHHCCCCCHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCE
TAVIGADTAGSAREIAEAGDVSRAAIASRLAADIYGLDILAENIEDEAHNTTRFIILSRG
EEEEECCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GEWTPAGNGPVVTTFVFRVRNVPAALYKALGGFATNGVNMTKLESYQLDGRFTATQFYAD
CCCCCCCCCCCHHHHHHHHHCCCHHHHHHHCCHHCCCCCEEEEEEEEECCEEEEEEEEEE
VDGHPDDRPVKLALEELAFFSREMRILGVYPAHPYRAQFAAEQETF
CCCCCCCCHHHHHHHHHHHHHHCEEEEEECCCCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]