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The map label for this gene is kdsB

Identifier: 154246571

GI number: 154246571

Start: 2918443

End: 2919210

Strand: Reverse

Name: kdsB

Synonym: Xaut_2630

Alternate gene names: 154246571

Gene position: 2919210-2918443 (Counterclockwise)

Preceding gene: 154246579

Following gene: 154246570

Centisome position: 54.99

GC content: 71.48

Gene sequence:

>768_bases
ATGTTCCCCGCTCTTTCCAGCGAACGCGTGCTCGTGCTGATCCCCGCGCGGATGGCGGCCACTCGCCTGCCGGGCAAGCC
TCTGGCCGACGTGGGCGGGCGCCCCATGATCGTGGAGGTGGCGCGGCGCGCCGCCGCAGCCGCCATCGGCCCGGTGGCCG
TGGCCACCGATTCCGAGGAGATCGCCGCCGCCGTGCGGGCCGCCGGCGTCACGGCGGTGCTGACCCGCGCCGACCATCCC
TCCGGCTCCGACCGGATCTTCGAGGCACTGGGCGCGCTGGACCCCGACGGCGCCGTGGATGTGGTGGTGAACGTGCAGGG
CGACCTGCCCACCATCGCCCCGCAGACCATCCGCAGCGCGCTCGCGCCCCTCGCTGAGCCGGCTGTGGACATCGCCACGC
TCTGCGCCGAGATCGTGGTGGAGGACGAGCGCACCGACCCCAACGTGGTCAAGGTGGTCGGCTCGCCCCTGGACGACAAC
CTGTTGCGCGCACTCTATTTCACCCGCGCCACCGCACCTTTTGGTGCCGGACCTCTGTACCACCACATCGGCCTCTATGC
CTATCGCCGGCCGGCGCTTGCCCGATTCGTCGCCCTCGCCCCCTCGATGCTGGAGCAGCGCGAGAAGCTGGAGCAGCTGC
GCGCGCTGGAAGCCGGCATGCGCATCGACGTGGCGGTGGTGGACGCGGTGCCGCTGGGGGTGGACACACAGGCCCATCTC
GACCGCGCCCGCGCGATTCTCGCGCTCGAAGCCGCCGAACAAAAATGA

Upstream 100 bases:

>100_bases
TAACCACTTTGATGTGAGCGAGGCAACCCGTATAAGGCGCGCCCCAATGCCACTCCCCGCGCCCGCATCGGACGCGGCCC
GAAGGGAGCCGCCGGCCGCC

Downstream 100 bases:

>100_bases
GGACATCATGATCCGCCGCATCACCTTCCAGGGCGAGCCGGGCGCCAATTCGCACATCGCCTGCCGCGAGGTGTTTCCGG
ATTTCGAGGCGGTGCCCTGC

Product: 3-deoxy-D-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 255; Mature: 255

Protein sequence:

>255_residues
MFPALSSERVLVLIPARMAATRLPGKPLADVGGRPMIVEVARRAAAAAIGPVAVATDSEEIAAAVRAAGVTAVLTRADHP
SGSDRIFEALGALDPDGAVDVVVNVQGDLPTIAPQTIRSALAPLAEPAVDIATLCAEIVVEDERTDPNVVKVVGSPLDDN
LLRALYFTRATAPFGAGPLYHHIGLYAYRRPALARFVALAPSMLEQREKLEQLRALEAGMRIDVAVVDAVPLGVDTQAHL
DRARAILALEAAEQK

Sequences:

>Translated_255_residues
MFPALSSERVLVLIPARMAATRLPGKPLADVGGRPMIVEVARRAAAAAIGPVAVATDSEEIAAAVRAAGVTAVLTRADHP
SGSDRIFEALGALDPDGAVDVVVNVQGDLPTIAPQTIRSALAPLAEPAVDIATLCAEIVVEDERTDPNVVKVVGSPLDDN
LLRALYFTRATAPFGAGPLYHHIGLYAYRRPALARFVALAPSMLEQREKLEQLRALEAGMRIDVAVVDAVPLGVDTQAHL
DRARAILALEAAEQK
>Mature_255_residues
MFPALSSERVLVLIPARMAATRLPGKPLADVGGRPMIVEVARRAAAAAIGPVAVATDSEEIAAAVRAAGVTAVLTRADHP
SGSDRIFEALGALDPDGAVDVVVNVQGDLPTIAPQTIRSALAPLAEPAVDIATLCAEIVVEDERTDPNVVKVVGSPLDDN
LLRALYFTRATAPFGAGPLYHHIGLYAYRRPALARFVALAPSMLEQREKLEQLRALEAGMRIDVAVVDAVPLGVDTQAHL
DRARAILALEAAEQK

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=249, Percent_Identity=46.1847389558233, Blast_Score=171, Evalue=5e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_XANP2 (A7IIM9)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001417529.1
- ProteinModelPortal:   A7IIM9
- SMR:   A7IIM9
- STRING:   A7IIM9
- GeneID:   5422271
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_2630
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   IIPARLK
- ProtClustDB:   CLSK979835
- BioCyc:   XAUT78245:XAUT_2630-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 26806; Mature: 26806

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFPALSSERVLVLIPARMAATRLPGKPLADVGGRPMIVEVARRAAAAAIGPVAVATDSEE
CCCCCCCCCEEEEECCHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCEEEECCHHH
IAAAVRAAGVTAVLTRADHPSGSDRIFEALGALDPDGAVDVVVNVQGDLPTIAPQTIRSA
HHHHHHHHCHHHEEEECCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHH
LAPLAEPAVDIATLCAEIVVEDERTDPNVVKVVGSPLDDNLLRALYFTRATAPFGAGPLY
HHHHHCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHH
HHIGLYAYRRPALARFVALAPSMLEQREKLEQLRALEAGMRIDVAVVDAVPLGVDTQAHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHH
DRARAILALEAAEQK
HHHHHHHHHHCCCCC
>Mature Secondary Structure
MFPALSSERVLVLIPARMAATRLPGKPLADVGGRPMIVEVARRAAAAAIGPVAVATDSEE
CCCCCCCCCEEEEECCHHHHHCCCCCCHHHCCCCCHHHHHHHHHHHHHHCCEEEECCHHH
IAAAVRAAGVTAVLTRADHPSGSDRIFEALGALDPDGAVDVVVNVQGDLPTIAPQTIRSA
HHHHHHHHCHHHEEEECCCCCCHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCHHHHHHH
LAPLAEPAVDIATLCAEIVVEDERTDPNVVKVVGSPLDDNLLRALYFTRATAPFGAGPLY
HHHHHCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCHHH
HHIGLYAYRRPALARFVALAPSMLEQREKLEQLRALEAGMRIDVAVVDAVPLGVDTQAHL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCHHHH
DRARAILALEAAEQK
HHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA