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The map label for this gene is ompR [H]

Identifier: 154246364

GI number: 154246364

Start: 2706135

End: 2706857

Strand: Direct

Name: ompR [H]

Synonym: Xaut_2423

Alternate gene names: 154246364

Gene position: 2706135-2706857 (Clockwise)

Preceding gene: 154246356

Following gene: 154246365

Centisome position: 50.97

GC content: 69.02

Gene sequence:

>723_bases
ATGGACAGCGCACCCCACATTGCCATCGTGGACGACCATCGCGACATCCGCGACCTCGTCGGCAAGTACCTGACCCAGCA
TGGCTATCGCACCAGCCTCGCGGACAGCGCGGCGGCCCTGCGGCGCCAGCTGGAGCGCGGTGCCGCGCCCGACCTCGTGG
TGCTGGACGTGATGATGCCGGGCGAGGATGGCCTGTCCCTGTGCCGCTTCCTGCGTAGCACCACCGACCTGCCGGTAATC
CTGCTCACCGCCATGGCGGAGGAGACCGACCGCATCGTGGGCCTCGAGATCGGCGCCGACGATTATGTGACCAAGCCGTT
CAGCCCGCGTGAGCTCTTGGCGCGCATCAAGGCGGTGCTGCGTCGCGTCCACAGCCTGCCGCCGCAGAAGGGGCACATCG
CCGCCAAGACCGTGCGCTTCGACCGCTGGCGGCTGGACGTGGGCCGCCGCGAGCTGATGGCGGAAGACGACGTGGCGGTG
CCGCTCAGCACCGCCGAGTTTCGCCTGCTGTGCGCCTTCCTCGACCATCCCGGTATCGTGCTGAGCCGCGACCAGCTGCT
CGACCTGACCGCCGGCCGCAGCGCCGATCCGTTCGACCGCAGCATCGACAACCAGGTCAGCCGCCTGCGCAAGAAGGTGG
AGGCCGATCCCAAGGTGCCGGCCCTCATCAAGACCCACTGGGGCGGGGGCTACAGCCTTGCAGCGGAGGTGGAACGCGCA
TGA

Upstream 100 bases:

>100_bases
CACCGGCGGGATCGCAAATCCGTGAACGGTTACAGTCTGATACACTTTTGCAGTGGGCAAGGCGCGCGCTCGGCCTATGG
TCCTTGAAGGAGCAGAGGAA

Downstream 100 bases:

>100_bases
TCCGCCTGTTCCGGCGCAGCCTCGCGGCGCGCTTCATCTGTTTCACCCTGGTCATTCTCGCCCTGTCGCAGGTGGTGGCA
TTCTGCATCTCGTGGGACCA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MDSAPHIAIVDDHRDIRDLVGKYLTQHGYRTSLADSAAALRRQLERGAAPDLVVLDVMMPGEDGLSLCRFLRSTTDLPVI
LLTAMAEETDRIVGLEIGADDYVTKPFSPRELLARIKAVLRRVHSLPPQKGHIAAKTVRFDRWRLDVGRRELMAEDDVAV
PLSTAEFRLLCAFLDHPGIVLSRDQLLDLTAGRSADPFDRSIDNQVSRLRKKVEADPKVPALIKTHWGGGYSLAAEVERA

Sequences:

>Translated_240_residues
MDSAPHIAIVDDHRDIRDLVGKYLTQHGYRTSLADSAAALRRQLERGAAPDLVVLDVMMPGEDGLSLCRFLRSTTDLPVI
LLTAMAEETDRIVGLEIGADDYVTKPFSPRELLARIKAVLRRVHSLPPQKGHIAAKTVRFDRWRLDVGRRELMAEDDVAV
PLSTAEFRLLCAFLDHPGIVLSRDQLLDLTAGRSADPFDRSIDNQVSRLRKKVEADPKVPALIKTHWGGGYSLAAEVERA
>Mature_240_residues
MDSAPHIAIVDDHRDIRDLVGKYLTQHGYRTSLADSAAALRRQLERGAAPDLVVLDVMMPGEDGLSLCRFLRSTTDLPVI
LLTAMAEETDRIVGLEIGADDYVTKPFSPRELLARIKAVLRRVHSLPPQKGHIAAKTVRFDRWRLDVGRRELMAEDDVAV
PLSTAEFRLLCAFLDHPGIVLSRDQLLDLTAGRSADPFDRSIDNQVSRLRKKVEADPKVPALIKTHWGGGYSLAAEVERA

Specific function: The N-terminus of this protein is required for the transcriptional expression of both major outer membrane protein genes ompF and ompC; its C-terminal moiety mediates the multimerization of the ompR protein. As a multimer, it turns on the expression of th

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=241, Percent_Identity=46.4730290456432, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1790863, Length=237, Percent_Identity=35.8649789029536, Blast_Score=160, Evalue=5e-41,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=40.7725321888412, Blast_Score=155, Evalue=2e-39,
Organism=Escherichia coli, GI1788394, Length=238, Percent_Identity=37.3949579831933, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1786599, Length=235, Percent_Identity=37.4468085106383, Blast_Score=144, Evalue=7e-36,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=37.719298245614, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=38.2608695652174, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786911, Length=228, Percent_Identity=35.9649122807018, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=35.042735042735, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=34.6491228070175, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87082012, Length=230, Percent_Identity=33.9130434782609, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1787375, Length=184, Percent_Identity=35.3260869565217, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790552, Length=213, Percent_Identity=33.8028169014084, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789402, Length=231, Percent_Identity=29.8701298701299, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1788550, Length=151, Percent_Identity=34.4370860927152, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26663; Mature: 26663

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSAPHIAIVDDHRDIRDLVGKYLTQHGYRTSLADSAAALRRQLERGAAPDLVVLDVMMP
CCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
GEDGLSLCRFLRSTTDLPVILLTAMAEETDRIVGLEIGADDYVTKPFSPRELLARIKAVL
CCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RRVHSLPPQKGHIAAKTVRFDRWRLDVGRRELMAEDDVAVPLSTAEFRLLCAFLDHPGIV
HHHHCCCCCCCCEEEHEEEHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEE
LSRDQLLDLTAGRSADPFDRSIDNQVSRLRKKVEADPKVPALIKTHWGGGYSLAAEVERA
EEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEHEECCCC
>Mature Secondary Structure
MDSAPHIAIVDDHRDIRDLVGKYLTQHGYRTSLADSAAALRRQLERGAAPDLVVLDVMMP
CCCCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEC
GEDGLSLCRFLRSTTDLPVILLTAMAEETDRIVGLEIGADDYVTKPFSPRELLARIKAVL
CCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHH
RRVHSLPPQKGHIAAKTVRFDRWRLDVGRRELMAEDDVAVPLSTAEFRLLCAFLDHPGIV
HHHHCCCCCCCCEEEHEEEHHHHHHCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCEE
LSRDQLLDLTAGRSADPFDRSIDNQVSRLRKKVEADPKVPALIKTHWGGGYSLAAEVERA
EEHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]