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The map label for this gene is hypA

Identifier: 154246125

GI number: 154246125

Start: 2441923

End: 2442264

Strand: Direct

Name: hypA

Synonym: Xaut_2182

Alternate gene names: 154246125

Gene position: 2441923-2442264 (Clockwise)

Preceding gene: 154246124

Following gene: 154246126

Centisome position: 46.0

GC content: 66.08

Gene sequence:

>342_bases
ATGCATGAGATGGCCGTGTGCGAGAGCCTGCTTTCCGCCATGGAAGAGGCGGCGAAGGCGCAGAATTTCTCCCGCGTCAC
CCGCGTGCGCCTTGCCATCGGCCGCTTCGCCGGCATCGAGGTGGAGGCTCTGCGCTTCGGCTTTGATGTGGTGATGCGGG
GTTCCCTCGCCGAGGGCGCCGAGCTGGTGGTGCTGGAAGAGGACGGCAGCGCCTGGTGCTTCGACTGCTGCGAGACGGTG
GCGCTCTCCCACCGCCTTGCCTCCTGCCCGAAATGCGGCGGGGAACGCCTCGTGCCCAATGGCGGCACGGACATGAAGAT
CAAGGACCTGGAGGTGTTGTGA

Upstream 100 bases:

>100_bases
CTGACACCCGACCCCACGGCACGGCGGCTGGCGCCGCTTCTGGTGTCGGCCATCAATCCCTGCGTGCCGGTCACTTTGTC
CTATGCGGAGGAGGCTGCCC

Downstream 100 bases:

>100_bases
TGTGCACGGTCTGCGGCTGTAGCGGCGACGGCGCCACCATTTCCGATGCGACGGGCGGACACGCCCATGCCCATCCCCAT
GAGCACGGCCATGAGCACGA

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHEMAVCESLLSAMEEAAKAQNFSRVTRVRLAIGRFAGIEVEALRFGFDVVMRGSLAEGAELVVLEEDGSAWCFDCCETV
ALSHRLASCPKCGGERLVPNGGTDMKIKDLEVL

Sequences:

>Translated_113_residues
MHEMAVCESLLSAMEEAAKAQNFSRVTRVRLAIGRFAGIEVEALRFGFDVVMRGSLAEGAELVVLEEDGSAWCFDCCETV
ALSHRLASCPKCGGERLVPNGGTDMKIKDLEVL
>Mature_113_residues
MHEMAVCESLLSAMEEAAKAQNFSRVTRVRLAIGRFAGIEVEALRFGFDVVMRGSLAEGAELVVLEEDGSAWCFDCCETV
ALSHRLASCPKCGGERLVPNGGTDMKIKDLEVL

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=112, Percent_Identity=36.6071428571429, Blast_Score=94, Evalue=3e-21,
Organism=Escherichia coli, GI1789081, Length=113, Percent_Identity=37.1681415929204, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_XANP2 (A7IHD3)

Other databases:

- EMBL:   CP000781
- RefSeq:   YP_001417083.1
- STRING:   A7IHD3
- GeneID:   5424740
- GenomeReviews:   CP000781_GR
- KEGG:   xau:Xaut_2182
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   MHEMSLC
- ProtClustDB:   CLSK979690
- BioCyc:   XAUT78245:XAUT_2182-MONOMER
- HAMAP:   MF_00213
- InterPro:   IPR000688
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12251; Mature: 12251

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.3 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
9.7 %Cys+Met (Translated Protein)
5.3 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
9.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMAVCESLLSAMEEAAKAQNFSRVTRVRLAIGRFAGIEVEALRFGFDVVMRGSLAEGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCC
ELVVLEEDGSAWCFDCCETVALSHRLASCPKCGGERLVPNGGTDMKIKDLEVL
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCEEECEECC
>Mature Secondary Structure
MHEMAVCESLLSAMEEAAKAQNFSRVTRVRLAIGRFAGIEVEALRFGFDVVMRGSLAEGA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECCCCCCCC
ELVVLEEDGSAWCFDCCETVALSHRLASCPKCGGERLVPNGGTDMKIKDLEVL
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCEEECEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA