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The map label for this gene is hypB [H]

Identifier: 154246126

GI number: 154246126

Start: 2442369

End: 2443310

Strand: Direct

Name: hypB [H]

Synonym: Xaut_2183

Alternate gene names: 154246126

Gene position: 2442369-2443310 (Clockwise)

Preceding gene: 154246125

Following gene: 154246127

Centisome position: 46.0

GC content: 71.97

Gene sequence:

>942_bases
GTGCACGGCGAGGGCCATTCCCACGGCCATGGCGAAGCCCATGTCCATACCCACGCGGACGGCACCACCCACAGCCACAG
CCACGGACACGGGCACGATCATGGTGACGGGCACGCCCATCACCACCACGATCATGACCACGCCCACCCCGCCGGCGACA
CCCTCGACTACGGCGCCGGCCCCGCCCGCGCCCATGCGCCGGGCCTTTCCCAGGCGCGCATGGTGGAGATCGAGACCTCC
ATCCTCGCGAAGAACGACGATTACGCCGCGAAGAACCGCGCCCGCTTCGAAGCCGGCGGCCTGCTCGCCCTGAACCTGCT
GTCCGGCCCCGGCGCGGGCAAGACCACGCTCCTGGTGGAGACGCTGAAGGCGCTGGCCGGCCGCCTGCCCACCGCCGTCA
TCGAGGGCGACCAGCAGACCGACAACGACGCCGCCCGCATCCGTGCAGCCGGGGCGCCGGCGGTGCAGATCAACACCGGC
AAGGGCTGCCACCTGGACGCCCACATGGTGGGGCACGCGGTGGAAAAGCTGCCGCTGCCGCCCGGCGGCGTGCTGTTCAT
CGAGAATGTGGGCAACCTCGTGTGCCCCGCCGCCTTCGACCTCGGAGAGACGGCCCGCATCACCCTCATCTCGGTGGCGG
AGGGCGACGACAAGCCGCTGAAATATCCTGACATCTTCGAGGGTGCCGACCTCGTCCTCATCACCAAGGCGGACCTTGCG
CCGCATGTGGACGCCGACATGGCGCAGCTCGAGGCCAACATCCGCCGGGTGAACCCGCGGGCCGACATCCTGCGCGTCTC
CGCGCGGGGCGAGGTGGGGCTCACCCGCTGGCTGGCGTGGCTGGAGAAGGCCCGCGCGGAGCGCCTCGACGCGCTCGCCG
CCGCCCGCGAGCGCGAGGCGCAGGCCCTGCGCGCGGCCATGGTGGCGGGAGGCGCGCGGTGA

Upstream 100 bases:

>100_bases
CACGGTCTGCGGCTGTAGCGGCGACGGCGCCACCATTTCCGATGCGACGGGCGGACACGCCCATGCCCATCCCCATGAGC
ACGGCCATGAGCACGATCAC

Downstream 100 bases:

>100_bases
ACCGCCGCCCCGCCATCCTCGTGGTGGACGACGAGCCGCGCTCGGTGGAAGTCATTGCCCGCGTGCTCGACGAGGAGTTC
GACGTCTTCACCGCGCTCAA

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MHGEGHSHGHGEAHVHTHADGTTHSHSHGHGHDHGDGHAHHHHDHDHAHPAGDTLDYGAGPARAHAPGLSQARMVEIETS
ILAKNDDYAAKNRARFEAGGLLALNLLSGPGAGKTTLLVETLKALAGRLPTAVIEGDQQTDNDAARIRAAGAPAVQINTG
KGCHLDAHMVGHAVEKLPLPPGGVLFIENVGNLVCPAAFDLGETARITLISVAEGDDKPLKYPDIFEGADLVLITKADLA
PHVDADMAQLEANIRRVNPRADILRVSARGEVGLTRWLAWLEKARAERLDALAAAREREAQALRAAMVAGGAR

Sequences:

>Translated_313_residues
MHGEGHSHGHGEAHVHTHADGTTHSHSHGHGHDHGDGHAHHHHDHDHAHPAGDTLDYGAGPARAHAPGLSQARMVEIETS
ILAKNDDYAAKNRARFEAGGLLALNLLSGPGAGKTTLLVETLKALAGRLPTAVIEGDQQTDNDAARIRAAGAPAVQINTG
KGCHLDAHMVGHAVEKLPLPPGGVLFIENVGNLVCPAAFDLGETARITLISVAEGDDKPLKYPDIFEGADLVLITKADLA
PHVDADMAQLEANIRRVNPRADILRVSARGEVGLTRWLAWLEKARAERLDALAAAREREAQALRAAMVAGGAR
>Mature_313_residues
MHGEGHSHGHGEAHVHTHADGTTHSHSHGHGHDHGDGHAHHHHDHDHAHPAGDTLDYGAGPARAHAPGLSQARMVEIETS
ILAKNDDYAAKNRARFEAGGLLALNLLSGPGAGKTTLLVETLKALAGRLPTAVIEGDQQTDNDAARIRAAGAPAVQINTG
KGCHLDAHMVGHAVEKLPLPPGGVLFIENVGNLVCPAAFDLGETARITLISVAEGDDKPLKYPDIFEGADLVLITKADLA
PHVDADMAQLEANIRRVNPRADILRVSARGEVGLTRWLAWLEKARAERLDALAAAREREAQALRAAMVAGGAR

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=232, Percent_Identity=57.3275862068966, Blast_Score=278, Evalue=2e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 33013; Mature: 33013

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHGEGHSHGHGEAHVHTHADGTTHSHSHGHGHDHGDGHAHHHHDHDHAHPAGDTLDYGAG
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PARAHAPGLSQARMVEIETSILAKNDDYAAKNRARFEAGGLLALNLLSGPGAGKTTLLVE
CCCCCCCCCCCCEEEEEEHHEEECCCCCCCCCCCEECCCCEEEEEEECCCCCCCHHHHHH
TLKALAGRLPTAVIEGDQQTDNDAARIRAAGAPAVQINTGKGCHLDAHMVGHAVEKLPLP
HHHHHHCCCCEEEECCCCCCCCCHHEEEECCCCEEEEECCCCCEEHHHHHHHHHHHCCCC
PGGVLFIENVGNLVCPAAFDLGETARITLISVAEGDDKPLKYPDIFEGADLVLITKADLA
CCCEEEEECCCCEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCC
PHVDADMAQLEANIRRVNPRADILRVSARGEVGLTRWLAWLEKARAERLDALAAAREREA
CCCCHHHHHHHHHHHCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALRAAMVAGGAR
HHHHHHHHHCCCC
>Mature Secondary Structure
MHGEGHSHGHGEAHVHTHADGTTHSHSHGHGHDHGDGHAHHHHDHDHAHPAGDTLDYGAG
CCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PARAHAPGLSQARMVEIETSILAKNDDYAAKNRARFEAGGLLALNLLSGPGAGKTTLLVE
CCCCCCCCCCCCEEEEEEHHEEECCCCCCCCCCCEECCCCEEEEEEECCCCCCCHHHHHH
TLKALAGRLPTAVIEGDQQTDNDAARIRAAGAPAVQINTGKGCHLDAHMVGHAVEKLPLP
HHHHHHCCCCEEEECCCCCCCCCHHEEEECCCCEEEEECCCCCEEHHHHHHHHHHHCCCC
PGGVLFIENVGNLVCPAAFDLGETARITLISVAEGDDKPLKYPDIFEGADLVLITKADLA
CCCEEEEECCCCEECCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCC
PHVDADMAQLEANIRRVNPRADILRVSARGEVGLTRWLAWLEKARAERLDALAAAREREA
CCCCHHHHHHHHHHHCCCCCHHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QALRAAMVAGGAR
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8486288 [H]