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The map label for this gene is fnr [H]

Identifier: 154246026

GI number: 154246026

Start: 2342977

End: 2343753

Strand: Direct

Name: fnr [H]

Synonym: Xaut_2083

Alternate gene names: 154246026

Gene position: 2342977-2343753 (Clockwise)

Preceding gene: 154246025

Following gene: 154246027

Centisome position: 44.13

GC content: 66.02

Gene sequence:

>777_bases
ATGCTGAACGCCCCGCCCCATGGGCCGCTTCCCGTCGCGGCATCGTCGCTCCTGGCTGGCGCCACTCCTGCGCAGGCGCT
TCTGCTCACAGAGAACGCCGCCCTTACCAATGGCCCGCCGCTGCTGTTCCAGCGCCTCACCGCGAAGGAGCGCGAGGAGG
TGCTGCGCGAGGGCCAGAAGCGCGTGGTCTATCGCGGCAAGATGCTGTTCTCACAAGGCACGCCCCACGATGGGATCTTC
CTGATCGAGAGTGGCCGCATCCGCGTCTTCTACATCGCGCCCTCGGGCCGCGAGATCACCCTGGCCTATTGGAACTCCGG
CAATTTCGTCGGCGGACCTGAGCTGTTCGGGCAGGGACAGCATGTGTGGTCGGGGGTTGCGGCCACCAATTCGGTAGTGG
TGCATCTGAACGGCAAGACGCTGCGCCGGCTCATCGCCCAGATGCCGGCCTTCGCCATCGGCCTCATCGAGGGGCTCACG
TTCAAGGGGAAATGCTACTCCGCCCTTGCCCAGATGCTGGGCACCCGATCGGTCACCGAGCGCCTCGCCCACCTGCTCCT
GCACCTCGCGGATTCCTATGGGGTGCGGGAGGACGGCGCCATCGTCGTCGGCACGGCGTTTACCCACGCCGACCTCGCCC
ACATGGTCGGGGCGACGCGGCAATGGGTCACCATCAGCCTCAAGCGCCTGCAGGAACAGGGCGTTCTGAAAGCCGAGAAG
GCCAAGATCGTGATCCATGACCTCGACGCGCTCCATGTGATGCGGGGCGACCGCTAA

Upstream 100 bases:

>100_bases
GTCGCTGTCGGTCTATTTATATAGTTAATCAACCAAATAACTTATAATAACTATGGTACGCTTCTTGCGGTTGAAAATCG
ATCCAACCTGGAGAGAAGCC

Downstream 100 bases:

>100_bases
GGCCCGTTGGGGGGCAAAAGGGGGTGCGCCGGTAAGGCAGGCACGGTGTGATCAAGAAAGAGGCGGGTCTCGAAAGGAGG
CAACTAATCGACACCCCCTC

Product: CRP/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 258; Mature: 258

Protein sequence:

>258_residues
MLNAPPHGPLPVAASSLLAGATPAQALLLTENAALTNGPPLLFQRLTAKEREEVLREGQKRVVYRGKMLFSQGTPHDGIF
LIESGRIRVFYIAPSGREITLAYWNSGNFVGGPELFGQGQHVWSGVAATNSVVVHLNGKTLRRLIAQMPAFAIGLIEGLT
FKGKCYSALAQMLGTRSVTERLAHLLLHLADSYGVREDGAIVVGTAFTHADLAHMVGATRQWVTISLKRLQEQGVLKAEK
AKIVIHDLDALHVMRGDR

Sequences:

>Translated_258_residues
MLNAPPHGPLPVAASSLLAGATPAQALLLTENAALTNGPPLLFQRLTAKEREEVLREGQKRVVYRGKMLFSQGTPHDGIF
LIESGRIRVFYIAPSGREITLAYWNSGNFVGGPELFGQGQHVWSGVAATNSVVVHLNGKTLRRLIAQMPAFAIGLIEGLT
FKGKCYSALAQMLGTRSVTERLAHLLLHLADSYGVREDGAIVVGTAFTHADLAHMVGATRQWVTISLKRLQEQGVLKAEK
AKIVIHDLDALHVMRGDR
>Mature_258_residues
MLNAPPHGPLPVAASSLLAGATPAQALLLTENAALTNGPPLLFQRLTAKEREEVLREGQKRVVYRGKMLFSQGTPHDGIF
LIESGRIRVFYIAPSGREITLAYWNSGNFVGGPELFGQGQHVWSGVAATNSVVVHLNGKTLRRLIAQMPAFAIGLIEGLT
FKGKCYSALAQMLGTRSVTERLAHLLLHLADSYGVREDGAIVVGTAFTHADLAHMVGATRQWVTISLKRLQEQGVLKAEK
AKIVIHDLDALHVMRGDR

Specific function: It is involved in the activation of genes necessary for anaerobic respiration [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=198, Percent_Identity=24.7474747474747, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789756, Length=181, Percent_Identity=28.7292817679558, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 27971; Mature: 27971

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNAPPHGPLPVAASSLLAGATPAQALLLTENAALTNGPPLLFQRLTAKEREEVLREGQK
CCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
RVVYRGKMLFSQGTPHDGIFLIESGRIRVFYIAPSGREITLAYWNSGNFVGGPELFGQGQ
EEEEECEEEECCCCCCCCEEEEECCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHCCCC
HVWSGVAATNSVVVHLNGKTLRRLIAQMPAFAIGLIEGLTFKGKCYSALAQMLGTRSVTE
HHHHHHCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHH
RLAHLLLHLADSYGVREDGAIVVGTAFTHADLAHMVGATRQWVTISLKRLQEQGVLKAEK
HHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECC
AKIVIHDLDALHVMRGDR
CEEEEEECCCHHHHCCCC
>Mature Secondary Structure
MLNAPPHGPLPVAASSLLAGATPAQALLLTENAALTNGPPLLFQRLTAKEREEVLREGQK
CCCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
RVVYRGKMLFSQGTPHDGIFLIESGRIRVFYIAPSGREITLAYWNSGNFVGGPELFGQGQ
EEEEECEEEECCCCCCCCEEEEECCCEEEEEECCCCCEEEEEEECCCCCCCCHHHHCCCC
HVWSGVAATNSVVVHLNGKTLRRLIAQMPAFAIGLIEGLTFKGKCYSALAQMLGTRSVTE
HHHHHHCCCCEEEEEECCHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHH
RLAHLLLHLADSYGVREDGAIVVGTAFTHADLAHMVGATRQWVTISLKRLQEQGVLKAEK
HHHHHHHHHHHHCCCCCCCCEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECC
AKIVIHDLDALHVMRGDR
CEEEEEECCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]