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The map label for this gene is atpC

Identifier: 154246025

GI number: 154246025

Start: 2342316

End: 2342735

Strand: Direct

Name: atpC

Synonym: Xaut_2082

Alternate gene names: 154246025

Gene position: 2342316-2342735 (Clockwise)

Preceding gene: 154246023

Following gene: 154246026

Centisome position: 44.12

GC content: 68.57

Gene sequence:

>420_bases
ATGGCGACCTTACCCTTTGAGCTGGTCTCGCCCGAGCGGCTCGTGTTTTCCGGCGCCGTGACCGAGGTGATCGTGCCCGG
CGCGGAAGGCGAATTCGGCGTGATGGCGGGCCATGCGCCCTTCATCGGCATGCTGAAGCCCGGCATCCTCACCATCAAGG
GTGACGGGGCGTCGCGCTCCTATTTCGTGCGCGGTGGCTTTGCCGAGGTGAACCCGGCCGGCCTCACCATCCTCGCCGAA
GAGGCGAAGCCGCTGGACGAGCTGGATCTGGGTGCGCTCCAGCAGCAGATCCAGGACGCCAAGGAAGACGTGGCCGACGC
CACCACCGACGAGAGCCGGCAGCGCGCGGCGCGCCAGCTCGCCGATCTTGAGCAGGTCTATACGGCGCTCGAGAGCGGCC
GCACCGGCGGCGGGCACTGA

Upstream 100 bases:

>100_bases
CTTCCTTCATGGAGTAAGGGCGTCCATCCGGTGGATGGCGTCCGGAGGAGCACCCGATGTTGGGGCGCCTCCCGTTCGGG
ACGACCCGGAGACGAGAATT

Downstream 100 bases:

>100_bases
GGCGCGACGGAGCGTTTCGCTTCTGCCTCGTGTGGGCGTGTCCGGACCGGCCGGTTGGTTCGATCCGGGTGAACCGGACA
GCGCCTTGGAGAGATGGATT

Product: F0F1 ATP synthase subunit epsilon

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F1 sector epsilon subunit; F-ATPase epsilon subunit [H]

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MATLPFELVSPERLVFSGAVTEVIVPGAEGEFGVMAGHAPFIGMLKPGILTIKGDGASRSYFVRGGFAEVNPAGLTILAE
EAKPLDELDLGALQQQIQDAKEDVADATTDESRQRAARQLADLEQVYTALESGRTGGGH

Sequences:

>Translated_139_residues
MATLPFELVSPERLVFSGAVTEVIVPGAEGEFGVMAGHAPFIGMLKPGILTIKGDGASRSYFVRGGFAEVNPAGLTILAE
EAKPLDELDLGALQQQIQDAKEDVADATTDESRQRAARQLADLEQVYTALESGRTGGGH
>Mature_138_residues
ATLPFELVSPERLVFSGAVTEVIVPGAEGEFGVMAGHAPFIGMLKPGILTIKGDGASRSYFVRGGFAEVNPAGLTILAEE
AKPLDELDLGALQQQIQDAKEDVADATTDESRQRAARQLADLEQVYTALESGRTGGGH

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane [H]

COG id: COG0355

COG function: function code C; F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase epsilon chain family [H]

Homologues:

Organism=Homo sapiens, GI50345991, Length=131, Percent_Identity=34.3511450381679, Blast_Score=76, Evalue=9e-15,
Organism=Homo sapiens, GI4502297, Length=131, Percent_Identity=34.3511450381679, Blast_Score=76, Evalue=9e-15,
Organism=Escherichia coli, GI1790169, Length=120, Percent_Identity=34.1666666666667, Blast_Score=72, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320200, Length=130, Percent_Identity=31.5384615384615, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001469
- InterPro:   IPR020546
- ProDom:   PD000944 [H]

Pfam domain/function: PF02823 ATP-synt_DE_N [H]

EC number: 3.6.3.14

Molecular weight: Translated: 14627; Mature: 14495

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATLPFELVSPERLVFSGAVTEVIVPGAEGEFGVMAGHAPFIGMLKPGILTIKGDGASRS
CCCCCCCCCCCCCEEECCCCEEEEECCCCCCCEEEECCCCEEECCCCCEEEEECCCCCCE
YFVRGGFAEVNPAGLTILAEEAKPLDELDLGALQQQIQDAKEDVADATTDESRQRAARQL
EEEECCCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ADLEQVYTALESGRTGGGH
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
ATLPFELVSPERLVFSGAVTEVIVPGAEGEFGVMAGHAPFIGMLKPGILTIKGDGASRS
CCCCCCCCCCCCEEECCCCEEEEECCCCCCCEEEECCCCEEECCCCCEEEEECCCCCCE
YFVRGGFAEVNPAGLTILAEEAKPLDELDLGALQQQIQDAKEDVADATTDESRQRAARQL
EEEECCCCEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
ADLEQVYTALESGRTGGGH
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA