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The map label for this gene is mmgC [H]

Identifier: 154244859

GI number: 154244859

Start: 1020975

End: 1022141

Strand: Direct

Name: mmgC [H]

Synonym: Xaut_0909

Alternate gene names: 154244859

Gene position: 1020975-1022141 (Clockwise)

Preceding gene: 154244857

Following gene: 154244861

Centisome position: 19.23

GC content: 67.01

Gene sequence:

>1167_bases
ATGGCCTTGGATCCGGGGACGCTGTCCCAGCTGCTTGATGCGATCCGCCGTTTCGTCGACGAGCGGTTGATCCCCGCAGA
GGCCGAGGTCGCCGAGGCGGATGCCATCCCGGCCGCCATTGTCGCGGAGATGCGCGATCTGGGGCTGTTCGGGCTGACCG
CTCCGGAGGACTTTGGCGGTCTCGGCCTCACCATGGAGGAAGAGGTGCTCGCGATGTTCGAGCTCGGCCGTGCGGCGCCG
GCATTCCGTTCCATGTTCGCCACCAACGTCGGCATCGGCATGCAGGGCATCGCCATCGACGGCACGCCGGAGCAGAAGGC
GAAATATCTGCCTGGCCTCGCGTCCGGCGAGATCGTCGGCTCGTTTGCCCTCACCGAGCCGGACGTGGGCTCCGACGCCG
GATCGGTGAAGACCACGGCGCGGCGCGACGGTGATGTCTATGTACTGAACGGGACCAAGCGGTTCATCACCAATGCGCCG
CACGCCGGGCTGTTCACCGTGATGGCGCGCACCGATCCCAGCCAGAAGGGCGCCTCTGGCGTCTCTGCCTTCGCCGTGGA
GCGCGGAACGCCCGGCCTCTTCACCGGCAAGCCGGAAAAGAAGATGGGCCAGCAGGGAGCCCATGTGTGCGACGTGATCT
TCGATGACTGTCGGGTCCCGGCGTCTGCACTTATCGGCGGCGTTGAGGGGCAGGGCTTCAAGACTGCCATGAAGGTGCTG
GACAAGGGCCGCCTGCACATCGCGGCCGCCTGCGTGGGGCTTTCGGAGCGCATCCTTGATGACATGCTGGCCTATGCGGT
GGGGCGCCGGCAGTTCGGCCGGCCCTTGGCTGATTTCCAGCTCCTCCAGGCCATGTTTGCCGACTCGAAGGCCGACGCCT
ACGCGGCGCGCTGCATGGTGCTCGATGCCGCCCGCAGGCGCGATGCCGGGCAGGACGTGAGCGTGGAAGCCTCCTGCGCC
AAGATGTTCGCCTCCGAGGCGGTGGGCCGGATCGCCGACCGCAATGTGCAGGTCCACGGCGGCAACGGCTATATCCGCGA
ATACCGGGCCGAGCAGCTCTATCGCGATGCCCGCCTGTTCCGGATCTATGAGGGTACCACCCAGGTCCAGCAGATCATCA
TCGCCAAGGCGCTCACCGCCGAGGCGAGGGCGCGCGCCGGACTTTAG

Upstream 100 bases:

>100_bases
TGCCAACTGAAGCCTTATATAAGGGAAGTTGTGCCTCCTTGCCTGTTCGGGTGTCTTGCGTATATATGCAAAGATATTGG
CATAAAATGCGGAGGATGTC

Downstream 100 bases:

>100_bases
GTTCCGGCGCGGAGACCGGCGTGGCCTCCCGTTCATCCGCGTGACGGGCGGCGGCTTCCGGATCGAGAATCTTGAAGTTC
GTCAGCATCTTATCGAGGTA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MALDPGTLSQLLDAIRRFVDERLIPAEAEVAEADAIPAAIVAEMRDLGLFGLTAPEDFGGLGLTMEEEVLAMFELGRAAP
AFRSMFATNVGIGMQGIAIDGTPEQKAKYLPGLASGEIVGSFALTEPDVGSDAGSVKTTARRDGDVYVLNGTKRFITNAP
HAGLFTVMARTDPSQKGASGVSAFAVERGTPGLFTGKPEKKMGQQGAHVCDVIFDDCRVPASALIGGVEGQGFKTAMKVL
DKGRLHIAAACVGLSERILDDMLAYAVGRRQFGRPLADFQLLQAMFADSKADAYAARCMVLDAARRRDAGQDVSVEASCA
KMFASEAVGRIADRNVQVHGGNGYIREYRAEQLYRDARLFRIYEGTTQVQQIIIAKALTAEARARAGL

Sequences:

>Translated_388_residues
MALDPGTLSQLLDAIRRFVDERLIPAEAEVAEADAIPAAIVAEMRDLGLFGLTAPEDFGGLGLTMEEEVLAMFELGRAAP
AFRSMFATNVGIGMQGIAIDGTPEQKAKYLPGLASGEIVGSFALTEPDVGSDAGSVKTTARRDGDVYVLNGTKRFITNAP
HAGLFTVMARTDPSQKGASGVSAFAVERGTPGLFTGKPEKKMGQQGAHVCDVIFDDCRVPASALIGGVEGQGFKTAMKVL
DKGRLHIAAACVGLSERILDDMLAYAVGRRQFGRPLADFQLLQAMFADSKADAYAARCMVLDAARRRDAGQDVSVEASCA
KMFASEAVGRIADRNVQVHGGNGYIREYRAEQLYRDARLFRIYEGTTQVQQIIIAKALTAEARARAGL
>Mature_387_residues
ALDPGTLSQLLDAIRRFVDERLIPAEAEVAEADAIPAAIVAEMRDLGLFGLTAPEDFGGLGLTMEEEVLAMFELGRAAPA
FRSMFATNVGIGMQGIAIDGTPEQKAKYLPGLASGEIVGSFALTEPDVGSDAGSVKTTARRDGDVYVLNGTKRFITNAPH
AGLFTVMARTDPSQKGASGVSAFAVERGTPGLFTGKPEKKMGQQGAHVCDVIFDDCRVPASALIGGVEGQGFKTAMKVLD
KGRLHIAAACVGLSERILDDMLAYAVGRRQFGRPLADFQLLQAMFADSKADAYAARCMVLDAARRRDAGQDVSVEASCAK
MFASEAVGRIADRNVQVHGGNGYIREYRAEQLYRDARLFRIYEGTTQVQQIIIAKALTAEARARAGL

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=380, Percent_Identity=40.2631578947368, Blast_Score=269, Evalue=4e-72,
Organism=Homo sapiens, GI4501859, Length=369, Percent_Identity=37.6693766937669, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI21361497, Length=384, Percent_Identity=38.0208333333333, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI226958412, Length=375, Percent_Identity=35.2, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI76496475, Length=381, Percent_Identity=37.5328083989501, Blast_Score=241, Evalue=9e-64,
Organism=Homo sapiens, GI4557235, Length=381, Percent_Identity=37.5328083989501, Blast_Score=241, Evalue=1e-63,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=36.7647058823529, Blast_Score=239, Evalue=2e-63,
Organism=Homo sapiens, GI187960098, Length=363, Percent_Identity=36.3636363636364, Blast_Score=235, Evalue=7e-62,
Organism=Homo sapiens, GI4557231, Length=363, Percent_Identity=36.3636363636364, Blast_Score=234, Evalue=8e-62,
Organism=Homo sapiens, GI7656849, Length=367, Percent_Identity=35.9673024523161, Blast_Score=216, Evalue=4e-56,
Organism=Homo sapiens, GI4501857, Length=381, Percent_Identity=33.3333333333333, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI4503943, Length=369, Percent_Identity=31.4363143631436, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI7669494, Length=339, Percent_Identity=32.1533923303835, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI48976061, Length=404, Percent_Identity=29.9504950495049, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI211971008, Length=404, Percent_Identity=29.9504950495049, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI38505218, Length=402, Percent_Identity=30.8457711442786, Blast_Score=141, Evalue=1e-33,
Organism=Escherichia coli, GI1786223, Length=362, Percent_Identity=31.4917127071823, Blast_Score=154, Evalue=7e-39,
Organism=Escherichia coli, GI87081958, Length=364, Percent_Identity=31.3186813186813, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI87082384, Length=298, Percent_Identity=26.510067114094, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081702, Length=293, Percent_Identity=27.3037542662116, Blast_Score=71, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17569725, Length=381, Percent_Identity=38.8451443569554, Blast_Score=257, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI17506239, Length=373, Percent_Identity=36.9973190348526, Blast_Score=246, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI17508101, Length=378, Percent_Identity=36.5079365079365, Blast_Score=243, Evalue=9e-65,
Organism=Caenorhabditis elegans, GI17538396, Length=373, Percent_Identity=36.1930294906166, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17570075, Length=375, Percent_Identity=36.8, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17534899, Length=365, Percent_Identity=37.5342465753425, Blast_Score=236, Evalue=1e-62,
Organism=Caenorhabditis elegans, GI71985184, Length=355, Percent_Identity=38.3098591549296, Blast_Score=232, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17533517, Length=375, Percent_Identity=31.7333333333333, Blast_Score=196, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI71990804, Length=293, Percent_Identity=38.9078498293515, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI71985192, Length=302, Percent_Identity=37.0860927152318, Blast_Score=184, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17534353, Length=372, Percent_Identity=31.1827956989247, Blast_Score=171, Evalue=7e-43,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=39.6551724137931, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI17505929, Length=373, Percent_Identity=30.5630026809651, Blast_Score=156, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71982178, Length=270, Percent_Identity=34.8148148148148, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI17551932, Length=375, Percent_Identity=26.9333333333333, Blast_Score=148, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI17531909, Length=250, Percent_Identity=33.6, Blast_Score=136, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17562446, Length=333, Percent_Identity=32.1321321321321, Blast_Score=121, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI17531913, Length=184, Percent_Identity=30.4347826086957, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=279, Percent_Identity=26.8817204301075, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI86563383, Length=279, Percent_Identity=26.8817204301075, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24660351, Length=379, Percent_Identity=37.7308707124011, Blast_Score=252, Evalue=3e-67,
Organism=Drosophila melanogaster, GI24666513, Length=366, Percent_Identity=36.8852459016393, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI21356377, Length=375, Percent_Identity=37.0666666666667, Blast_Score=235, Evalue=4e-62,
Organism=Drosophila melanogaster, GI281363737, Length=379, Percent_Identity=35.3562005277045, Blast_Score=227, Evalue=1e-59,
Organism=Drosophila melanogaster, GI24646207, Length=371, Percent_Identity=36.1185983827493, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI21355753, Length=370, Percent_Identity=34.8648648648649, Blast_Score=216, Evalue=3e-56,
Organism=Drosophila melanogaster, GI19920834, Length=371, Percent_Identity=29.9191374663073, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI24652780, Length=354, Percent_Identity=25.4237288135593, Blast_Score=93, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 41343; Mature: 41212

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDPGTLSQLLDAIRRFVDERLIPAEAEVAEADAIPAAIVAEMRDLGLFGLTAPEDFGG
CCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCEEECCCCCCCCC
LGLTMEEEVLAMFELGRAAPAFRSMFATNVGIGMQGIAIDGTPEQKAKYLPGLASGEIVG
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCCCEEE
SFALTEPDVGSDAGSVKTTARRDGDVYVLNGTKRFITNAPHAGLFTVMARTDPSQKGASG
EEEECCCCCCCCCCCCCCHHCCCCCEEEECCCHHHHCCCCCCCEEEEEECCCCCCCCCCC
VSAFAVERGTPGLFTGKPEKKMGQQGAHVCDVIFDDCRVPASALIGGVEGQGFKTAMKVL
CCCEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHH
DKGRLHIAAACVGLSERILDDMLAYAVGRRQFGRPLADFQLLQAMFADSKADAYAARCMV
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHH
LDAARRRDAGQDVSVEASCAKMFASEAVGRIADRNVQVHGGNGYIREYRAEQLYRDARLF
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHE
RIYEGTTQVQQIIIAKALTAEARARAGL
EEECCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ALDPGTLSQLLDAIRRFVDERLIPAEAEVAEADAIPAAIVAEMRDLGLFGLTAPEDFGG
CCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHCCEEECCCCCCCCC
LGLTMEEEVLAMFELGRAAPAFRSMFATNVGIGMQGIAIDGTPEQKAKYLPGLASGEIVG
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHCCCCCCCCEEE
SFALTEPDVGSDAGSVKTTARRDGDVYVLNGTKRFITNAPHAGLFTVMARTDPSQKGASG
EEEECCCCCCCCCCCCCCHHCCCCCEEEECCCHHHHCCCCCCCEEEEEECCCCCCCCCCC
VSAFAVERGTPGLFTGKPEKKMGQQGAHVCDVIFDDCRVPASALIGGVEGQGFKTAMKVL
CCCEEEECCCCCCCCCCCHHHHHHCCCHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHH
DKGRLHIAAACVGLSERILDDMLAYAVGRRQFGRPLADFQLLQAMFADSKADAYAARCMV
HCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHH
LDAARRRDAGQDVSVEASCAKMFASEAVGRIADRNVQVHGGNGYIREYRAEQLYRDARLF
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHE
RIYEGTTQVQQIIIAKALTAEARARAGL
EEECCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]