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The map label for this gene is maoC [H]

Identifier: 154244857

GI number: 154244857

Start: 1011209

End: 1013272

Strand: Direct

Name: maoC [H]

Synonym: Xaut_0907

Alternate gene names: 154244857

Gene position: 1011209-1013272 (Clockwise)

Preceding gene: 154244856

Following gene: 154244859

Centisome position: 19.05

GC content: 69.77

Gene sequence:

>2064_bases
ATGACGAAACTCCTCAACAGCTACGCCCTCGACCGCTGGTTCGTGCCGCAAGAGGGCCTCATCGACATCCCCAGCGCCGT
TGACGGCCGCGTGGTGGCGCGCACCTCCACCAGGGGGCTGGATCTTGCCGCCATGGTGCGCCATGCCCGCGATGCGGGTG
GGCCGGCCCTGCGCGCGCTCACCTTCCACGAGCGGGCCGACATGCTGAAGGCGCTCGCCGCCCATCTCGGCGCCCACAAG
GAGGCACTCTACGCCCTCGCTGCCGACACCGGGGCCACCAGGCGGGACAATCTCATCGACATCGATGGCGGCATCGGCAC
CCTCTACGCCTATGCCTCGCGCGGACGGCGGGAGCTGCCGGGCGAGCGCTTCGTGGTGGAGGGCGGGCCGGAGGGCCTTT
CCAAGGGTGGCTCCTTCATCGGCCTTCACATCCTCACGCCGTTGAAGGGCGTGGCGGTGCATGTGAACGCCTTCAACTTC
CCCTGCTGGGGTCTTCTGGAGAAGCTCGCCCCCGCGCTCCTCGCCGGCGTGCCGGTCATCACCAAGCCGGCCACCGCCAC
CGCTTATGTGGCCGAGGCGGTGGTGCGGCTGATCGTGGAGGCGAACGTCCTGCCGAAGGGTGCGCTGCAACTGGTGTGCG
GATCGGCCGGCGACCTGCTGGATCACCTCACCGGACAGGATGTGCTCTCCTTCACCGGCTCGGCTGAGACCTCGCAGCTG
TTGCGCGATCATCCGGCGGTGTCGCGCAACGCGGTGCGCTTCATCGCCGAGCGGGATTCGCTCAACGCCGCCGTGCTCGG
CCCGGACGCCACCGAGGGCGCCCCCGAGTTCGACCTCTTCATCAAGGAGGTGGTACGCGAGATGACGGTGAAGGCGGGTC
AGAAATGCACCGCCATTCGCCGCATTATCGTGCCCCGTGCCCAGGAAAGCGCGGTGATCGCCGCGCTGAAGGGCCAGCTG
GCGAAGATCACCCTCGGCGATCCCCGCCGTGATGACGTGCGCATGGGTCCGCTCGCGAGCCTGGCCCAGCGCGAGGCCGC
ACGTGCGGCGGTGGCGCAGATCGCGCAGGAGGCGGAGATCGTCTTCGGCGATCACGATGCGGCCGAGCCCGTCGGGGCGG
ATGCGCAGGCCGGCGCCTTCATGACGCCGGTGCTGCTGCGTTGCGCGAGGCCGCTGGCGGCGAGGGCGCCCCATGCTGTG
GAGGCCTTCGGCCCGGTGGCGACCGTCATGGCCTATGACCGGCTCGATGACGCGGTGGCGCTGGTGGCGAAGGGGGAGGG
CAGCCTCGTCGCCTCTGTCTTCACTTATGATCCGCAGGTGGCCGACACGCTGGTGTTCGGCATCGCCGCCCATCACGGCC
GGCTGCTGGTGCTCGACCGCGACTGCGCCGGGGAATCGACCGGCCACGGCTCGCCCCTGCCGGGCCTGGTGCATGGCGGC
CCCGGCCGCGCCGGCGGCGGCGAGGAGATGGGCGGGCTGCGCGGGGTGTTCCATTACATGCAGCGCACCGCGCTGGAAGG
CTCCCCCGCGCGGCTATCGGCCTTGAGCCGCACCTGGCTTTCCGGCGCGCCGGCCCGCGTGACCGCCGAGCATCCCTTCA
AGCGGGATTATGAAGCGCTGAGCGTGGGCGACACGGTGGAGACGGCGTCGCGCGTCATCAGCCTCGACGACATCGAGCAT
TTCGCCCATTTCACCGGCGACACCTTCTATGCACACATGGATGAGGCGGCGGCCAAGGCCAACCCCTTCTTCCCGGGCCG
GGTGGCCCACGGCTATCTCATATTGTCGTTTGCCGCCGGGCTGTTTGTGGATCCCGCGCCGGGGCCGCTCCTGGCCAATT
ACGGCCTCGACACCCTGCGCTTCCTGAAGCCGGTCTCGCCGGGTGATGCCATCCGCGTGCGGCTCACCGTCAAGCACAAG
CAGCCCGGCCGCCGGCCCGACTATGGCGAGGTGCGCTGGGACGCCGAGGTGTTCAACCAGAACGGCGAGACGGTGGCGCG
CTATGAGCTGCTGACCATGAGCGCGCGGGCTTTGGAGGCAGCGCCCGTGCGCGTTGCGGTGTGA

Upstream 100 bases:

>100_bases
GCGGCGCCGGATCTGAACCCGCGCCCCTGCTGGTGGCTCTCGCCCGCGACGGACACAGCTTCGCCGACTGGCAACCGACA
CAATTGGGAGGACAACAGCC

Downstream 100 bases:

>100_bases
AATCCAGCCGGACCAACACGCCACGTGCCCGATGGCGTGGTTCGGCCGGCGGCGTGGTGCGGATTTTTTCCGGAATTTCG
ACGCGTCGGCGGCCGCGAGC

Product: bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase

Products: NA

Alternate protein names: Phenylacetic acid degradation protein paaZ [H]

Number of amino acids: Translated: 687; Mature: 686

Protein sequence:

>687_residues
MTKLLNSYALDRWFVPQEGLIDIPSAVDGRVVARTSTRGLDLAAMVRHARDAGGPALRALTFHERADMLKALAAHLGAHK
EALYALAADTGATRRDNLIDIDGGIGTLYAYASRGRRELPGERFVVEGGPEGLSKGGSFIGLHILTPLKGVAVHVNAFNF
PCWGLLEKLAPALLAGVPVITKPATATAYVAEAVVRLIVEANVLPKGALQLVCGSAGDLLDHLTGQDVLSFTGSAETSQL
LRDHPAVSRNAVRFIAERDSLNAAVLGPDATEGAPEFDLFIKEVVREMTVKAGQKCTAIRRIIVPRAQESAVIAALKGQL
AKITLGDPRRDDVRMGPLASLAQREAARAAVAQIAQEAEIVFGDHDAAEPVGADAQAGAFMTPVLLRCARPLAARAPHAV
EAFGPVATVMAYDRLDDAVALVAKGEGSLVASVFTYDPQVADTLVFGIAAHHGRLLVLDRDCAGESTGHGSPLPGLVHGG
PGRAGGGEEMGGLRGVFHYMQRTALEGSPARLSALSRTWLSGAPARVTAEHPFKRDYEALSVGDTVETASRVISLDDIEH
FAHFTGDTFYAHMDEAAAKANPFFPGRVAHGYLILSFAAGLFVDPAPGPLLANYGLDTLRFLKPVSPGDAIRVRLTVKHK
QPGRRPDYGEVRWDAEVFNQNGETVARYELLTMSARALEAAPVRVAV

Sequences:

>Translated_687_residues
MTKLLNSYALDRWFVPQEGLIDIPSAVDGRVVARTSTRGLDLAAMVRHARDAGGPALRALTFHERADMLKALAAHLGAHK
EALYALAADTGATRRDNLIDIDGGIGTLYAYASRGRRELPGERFVVEGGPEGLSKGGSFIGLHILTPLKGVAVHVNAFNF
PCWGLLEKLAPALLAGVPVITKPATATAYVAEAVVRLIVEANVLPKGALQLVCGSAGDLLDHLTGQDVLSFTGSAETSQL
LRDHPAVSRNAVRFIAERDSLNAAVLGPDATEGAPEFDLFIKEVVREMTVKAGQKCTAIRRIIVPRAQESAVIAALKGQL
AKITLGDPRRDDVRMGPLASLAQREAARAAVAQIAQEAEIVFGDHDAAEPVGADAQAGAFMTPVLLRCARPLAARAPHAV
EAFGPVATVMAYDRLDDAVALVAKGEGSLVASVFTYDPQVADTLVFGIAAHHGRLLVLDRDCAGESTGHGSPLPGLVHGG
PGRAGGGEEMGGLRGVFHYMQRTALEGSPARLSALSRTWLSGAPARVTAEHPFKRDYEALSVGDTVETASRVISLDDIEH
FAHFTGDTFYAHMDEAAAKANPFFPGRVAHGYLILSFAAGLFVDPAPGPLLANYGLDTLRFLKPVSPGDAIRVRLTVKHK
QPGRRPDYGEVRWDAEVFNQNGETVARYELLTMSARALEAAPVRVAV
>Mature_686_residues
TKLLNSYALDRWFVPQEGLIDIPSAVDGRVVARTSTRGLDLAAMVRHARDAGGPALRALTFHERADMLKALAAHLGAHKE
ALYALAADTGATRRDNLIDIDGGIGTLYAYASRGRRELPGERFVVEGGPEGLSKGGSFIGLHILTPLKGVAVHVNAFNFP
CWGLLEKLAPALLAGVPVITKPATATAYVAEAVVRLIVEANVLPKGALQLVCGSAGDLLDHLTGQDVLSFTGSAETSQLL
RDHPAVSRNAVRFIAERDSLNAAVLGPDATEGAPEFDLFIKEVVREMTVKAGQKCTAIRRIIVPRAQESAVIAALKGQLA
KITLGDPRRDDVRMGPLASLAQREAARAAVAQIAQEAEIVFGDHDAAEPVGADAQAGAFMTPVLLRCARPLAARAPHAVE
AFGPVATVMAYDRLDDAVALVAKGEGSLVASVFTYDPQVADTLVFGIAAHHGRLLVLDRDCAGESTGHGSPLPGLVHGGP
GRAGGGEEMGGLRGVFHYMQRTALEGSPARLSALSRTWLSGAPARVTAEHPFKRDYEALSVGDTVETASRVISLDDIEHF
AHFTGDTFYAHMDEAAAKANPFFPGRVAHGYLILSFAAGLFVDPAPGPLLANYGLDTLRFLKPVSPGDAIRVRLTVKHKQ
PGRRPDYGEVRWDAEVFNQNGETVARYELLTMSARALEAAPVRVAV

Specific function: Phenylacetic acid aerobic catabolism. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=437, Percent_Identity=25.858123569794, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI21361176, Length=454, Percent_Identity=26.2114537444934, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI25777724, Length=464, Percent_Identity=24.3534482758621, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI115387104, Length=478, Percent_Identity=23.8493723849372, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI25777728, Length=351, Percent_Identity=25.3561253561254, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI310128091, Length=289, Percent_Identity=25.9515570934256, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI310128103, Length=289, Percent_Identity=25.9515570934256, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI188035924, Length=289, Percent_Identity=25.9515570934256, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI310128093, Length=289, Percent_Identity=25.6055363321799, Blast_Score=75, Evalue=3e-13,
Organism=Homo sapiens, GI153266822, Length=390, Percent_Identity=25.1282051282051, Blast_Score=74, Evalue=6e-13,
Organism=Homo sapiens, GI4507229, Length=352, Percent_Identity=26.1363636363636, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI25777732, Length=455, Percent_Identity=25.4945054945055, Blast_Score=68, Evalue=4e-11,
Organism=Homo sapiens, GI238814322, Length=294, Percent_Identity=24.4897959183673, Blast_Score=66, Evalue=1e-10,
Organism=Escherichia coli, GI1787653, Length=661, Percent_Identity=52.6475037821483, Blast_Score=615, Evalue=1e-177,
Organism=Escherichia coli, GI1787684, Length=450, Percent_Identity=24.8888888888889, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1787250, Length=448, Percent_Identity=25.8928571428571, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789015, Length=496, Percent_Identity=25, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI1788042, Length=415, Percent_Identity=28.9156626506024, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787715, Length=359, Percent_Identity=25.9052924791086, Blast_Score=81, Evalue=3e-16,
Organism=Escherichia coli, GI1787558, Length=391, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1786504, Length=488, Percent_Identity=25.2049180327869, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87082295, Length=508, Percent_Identity=23.4251968503937, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87081896, Length=352, Percent_Identity=25.2840909090909, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI87081926, Length=343, Percent_Identity=21.5743440233236, Blast_Score=64, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI115534176, Length=377, Percent_Identity=28.1167108753316, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI25143874, Length=398, Percent_Identity=22.6130653266332, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25143876, Length=398, Percent_Identity=22.6130653266332, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI133930964, Length=441, Percent_Identity=24.2630385487528, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17562198, Length=307, Percent_Identity=26.7100977198697, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17551164, Length=311, Percent_Identity=25.4019292604502, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI32564736, Length=294, Percent_Identity=26.1904761904762, Blast_Score=65, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6320917, Length=433, Percent_Identity=24.9422632794457, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281362580, Length=403, Percent_Identity=24.317617866005, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI62472918, Length=403, Percent_Identity=24.317617866005, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI62472926, Length=403, Percent_Identity=24.317617866005, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI62472936, Length=403, Percent_Identity=24.317617866005, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21356737, Length=403, Percent_Identity=24.317617866005, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129399, Length=340, Percent_Identity=25.2941176470588, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR002539
- InterPro:   IPR011966 [H]

Pfam domain/function: PF00171 Aldedh; PF01575 MaoC_dehydratas [H]

EC number: NA

Molecular weight: Translated: 72874; Mature: 72743

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKLLNSYALDRWFVPQEGLIDIPSAVDGRVVARTSTRGLDLAAMVRHARDAGGPALRAL
CCCHHHHHHHCCCCCCCCCCEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEE
TFHERADMLKALAAHLGAHKEALYALAADTGATRRDNLIDIDGGIGTLYAYASRGRRELP
HHHHHHHHHHHHHHHHCCCHHHHEEEECCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCC
GERFVVEGGPEGLSKGGSFIGLHILTPLKGVAVHVNAFNFPCWGLLEKLAPALLAGVPVI
CCEEEEECCCHHHHCCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCE
TKPATATAYVAEAVVRLIVEANVLPKGALQLVCGSAGDLLDHLTGQDVLSFTGSAETSQL
ECCCHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCHHHHHHHCCCCHHHHHCCCHHHHHH
LRDHPAVSRNAVRFIAERDSLNAAVLGPDATEGAPEFDLFIKEVVREMTVKAGQKCTAIR
HHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
RIIVPRAQESAVIAALKGQLAKITLGDPRRDDVRMGPLASLAQREAARAAVAQIAQEAEI
HHHCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEE
VFGDHDAAEPVGADAQAGAFMTPVLLRCARPLAARAPHAVEAFGPVATVMAYDRLDDAVA
EECCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHCCCEEE
LVAKGEGSLVASVFTYDPQVADTLVFGIAAHHGRLLVLDRDCAGESTGHGSPLPGLVHGG
EEECCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEECC
PGRAGGGEEMGGLRGVFHYMQRTALEGSPARLSALSRTWLSGAPARVTAEHPFKRDYEAL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCHHH
SVGDTVETASRVISLDDIEHFAHFTGDTFYAHMDEAAAKANPFFPGRVAHGYLILSFAAG
CCCCHHHHHHHHCCHHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCCHHHHHHHHEEHHHH
LFVDPAPGPLLANYGLDTLRFLKPVSPGDAIRVRLTVKHKQPGRRPDYGEVRWDAEVFNQ
HEECCCCCCEEECCCCHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCEEECHHHHCC
NGETVARYELLTMSARALEAAPVRVAV
CCCEEEEEHHHHHHHHHHHCCCEEEEC
>Mature Secondary Structure 
TKLLNSYALDRWFVPQEGLIDIPSAVDGRVVARTSTRGLDLAAMVRHARDAGGPALRAL
CCHHHHHHHCCCCCCCCCCEECCCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCEEEE
TFHERADMLKALAAHLGAHKEALYALAADTGATRRDNLIDIDGGIGTLYAYASRGRRELP
HHHHHHHHHHHHHHHHCCCHHHHEEEECCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCC
GERFVVEGGPEGLSKGGSFIGLHILTPLKGVAVHVNAFNFPCWGLLEKLAPALLAGVPVI
CCEEEEECCCHHHHCCCCEEEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCE
TKPATATAYVAEAVVRLIVEANVLPKGALQLVCGSAGDLLDHLTGQDVLSFTGSAETSQL
ECCCHHHHHHHHHHHHHHHHCCCCCCCHHHEEECCHHHHHHHCCCCHHHHHCCCHHHHHH
LRDHPAVSRNAVRFIAERDSLNAAVLGPDATEGAPEFDLFIKEVVREMTVKAGQKCTAIR
HHCCCCCCHHHHHHHHHCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHH
RIIVPRAQESAVIAALKGQLAKITLGDPRRDDVRMGPLASLAQREAARAAVAQIAQEAEI
HHHCCCCCCHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEE
VFGDHDAAEPVGADAQAGAFMTPVLLRCARPLAARAPHAVEAFGPVATVMAYDRLDDAVA
EECCCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHCCCEEE
LVAKGEGSLVASVFTYDPQVADTLVFGIAAHHGRLLVLDRDCAGESTGHGSPLPGLVHGG
EEECCCCCEEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCEECC
PGRAGGGEEMGGLRGVFHYMQRTALEGSPARLSALSRTWLSGAPARVTAEHPFKRDYEAL
CCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCCHHH
SVGDTVETASRVISLDDIEHFAHFTGDTFYAHMDEAAAKANPFFPGRVAHGYLILSFAAG
CCCCHHHHHHHHCCHHHHHHHHHHCCCEEEEEHHHHHHHCCCCCCCHHHHHHHHEEHHHH
LFVDPAPGPLLANYGLDTLRFLKPVSPGDAIRVRLTVKHKQPGRRPDYGEVRWDAEVFNQ
HEECCCCCCEEECCCCHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCEEECHHHHCC
NGETVARYELLTMSARALEAAPVRVAV
CCCEEEEEHHHHHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9097039; 9278503; 10766858 [H]