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The map label for this gene is fadN [H]

Identifier: 152977275

GI number: 152977275

Start: 3654416

End: 3656797

Strand: Reverse

Name: fadN [H]

Synonym: Bcer98_3597

Alternate gene names: 152977275

Gene position: 3656797-3654416 (Counterclockwise)

Preceding gene: 152977278

Following gene: 152977274

Centisome position: 89.47

GC content: 37.99

Gene sequence:

>2382_bases
ATGTTCCAAATTAAAAAGGCTGCTGTTCTCGGTTCTGGCGTAATGGGCTCAGGGATTGCGGCACATTTAGCCAATATCGG
TATACCAACATTATTGCTTGATATTGTGCCACGGGCACTGACAAAAGAAGAGGAAGCAAAGGGACTTACACTAGAGCATA
AAAGTGTAAGAAATCGATTTAGTAATGGAGCGCTGCAAAAATTAGTGAAACAAAAACCAGCTCCTCTTGCTGTGAAGGAT
AACTTGGCACTGATTACAACAGGGAATTTAGAGGATGATCTTGAACGCCTTGCTGAAGTAGACTGGATTATTGAAGTTGT
TGTTGAAAATTTAGATATAAAAAAACAACTATTTGAAAAAGTAGATGCAGTTCGTAAACTTGGTACGATTGTAAGTTCGA
ATACATCCGGCATTTCCGTTGAAAAAATGGCAGAAGGTCGTTCAGACGACTTCAAAAAACACTTCTTAGGAACGCACTTC
TTTAACCCACCACGATATTTAAAACTTCTAGAGATTATACCGACAAACGATACAGACCCACAAGTGTTGAACTTCATGAA
ACAATTTGGCGAAGATGTTCTTGGAAAAGGTGTTGTTATTGCAAAAGATACACCGAATTTTATCGGAAATCGCATCGGAA
CGTACGGGTTACTTGTAACACTTCGTGAAATGATGGAACGCGGATATAGCGTTGGTGAAGTGGATTCTGTAACAGGACCA
TTAATTGGGCGACCAAAGAGTGCAACATTCCGTACATTAGATGTTGTCGGATTAGATACGTTTGTTCATGTTGCAAATAA
TGTATATGAAAATGTGCAGGAAGAAGAAAGAGATGTCTTTAAGGTGCCTACTTTCATGCATGAAATGCTCGATAGAAAAT
GGCTTGGAAGCAAAACGGGGCAAGGGTTCTTCTTAAAGAAAGGAAAAGAGATTTTAGAATTAAATCCTAAAACGATGGAA
TATGAAGAGCGTAAAAAATTAAAAGCTGCATCTGTAGAATTAAGCAAACAAGAAAAAGGATTAGCAAATAAATTGAAAGC
GCTTGTATATGCAAAAGATCGTGCAGGAGAGTTATTATGGAATATTATCACACCAACTCTTTTATATTCTGCGAAACTTT
ATAAGGAAATCGCTGATGATATTGTAGCAATTGACCAAGCGATGAAATGGGGCTTCGGTTGGGAGCAAGGTCCATTTGAA
ATTTGGGATGCAATAGGAGTAGAAAAATCTGTTCAAAAGATGGAGGAAAACGGTAAGGTCGTTCCAGCATGGGTGAAAGA
AATGCTACAGAATGGTTTTGCTACTTTCTATAAGCATGATAGCGGTGAAAGTTATTATTACGATAATGGAGAATACAAGC
GAATTGAGCGAAATAAAAAAGCAATTTCTCTGAAACAATTAAAAGAGAAACATGGTGTTATTAAGAAAAATAGCGGAGCG
AGTTTAATTGATTTAGGTGACGGTATTCTTTGCCTAGAGTTCCATTCAAAGAGCAATGCAATCGGTATGGATATTACGCA
AATGATTAACTACGCTGTTGATGAAGTAGAGAAAAATTATAAAGGGCTTGTGATTGGAAACCAGTCGAAAAACTTCTGCG
TTGGTGCAAATTTAGCGATGATTTTAATGGAAGCACAAGATGATAACTACTTTGAAATTGAGTGGGTTGTAAAAAGCTTC
CAAGATGCGATGATGAAAATTAAATACTGTTCTAAGCCGGTAGTCGCAGCTCCATACGGCATGACGCTTGGCGGCGGTAC
AGAAGTTTGCTTGCCGACAGCTAGTATTCAAGCTTCTAGTGAAACATATATGGGATTAGTGGAAGTTGGTGTAGGTCTTA
TCCCTGGTGGAGGCGGCAATAAAGAGTTATATATAAAACATTTAAATAAAATGGCAAAAGGCGTAGAGTTTGATTTGCAA
AAGGTTGCAAATAAAGTGTTTGAAACAATAGCAATGGCGAAAGTTTCGACATCTGGACAAGAAGCAATTTCTCATAATTT
CTTAGGGGATAAAGACGGCATTAGTGTGAATGGCGATCACTTATTATATGATGCAAAACAAAAAGCTCTTGCACTATATG
AAGCGGGGTATAAACCGCCAATTCGTAAAAAGGTTCCCGTTGTTGGTGAAACAGGATATGCAACGCTTGTACTAGGTGCA
GAGGCAATGCATTTATCTGGTTATATTTCAGAATACGATCTCCATATTGCGAAAAAGCTTGCATACGTCATTGCGGGTGG
AAAGGTACCTTATGGAACAGAAGTTGATGAGCAATATTTATTAGATATAGAGCGTGAAGCGTTTATGAGTTTAATAAGTG
AGATGAAATCACAAGCAAGAATGCAGCACATGCTTGTAAAAGGAAAGCCATTACGTAACTAA

Upstream 100 bases:

>100_bases
CAAGCGGTATCATATATTTATTAGTAGAGGCTCACTCATTGATTGCGACGTATGTCGAAAAATTGAATGAGCATTCATTC
AAGAATAGGGGGAGAAATGG

Downstream 100 bases:

>100_bases
TAACGAGGGGAGATATCGTTCATGAGAGAAGCTGTCATTGTTGCAGGAGCAAGAACTCCGGTTGGAAAAGCAAAAAAAGG
TTCATTAAAAACAGTTCGTC

Product: 3-hydroxyacyl-CoA dehydrogenase NAD-binding

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 793; Mature: 793

Protein sequence:

>793_residues
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPRALTKEEEAKGLTLEHKSVRNRFSNGALQKLVKQKPAPLAVKD
NLALITTGNLEDDLERLAEVDWIIEVVVENLDIKKQLFEKVDAVRKLGTIVSSNTSGISVEKMAEGRSDDFKKHFLGTHF
FNPPRYLKLLEIIPTNDTDPQVLNFMKQFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLREMMERGYSVGEVDSVTGP
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEEERDVFKVPTFMHEMLDRKWLGSKTGQGFFLKKGKEILELNPKTME
YEERKKLKAASVELSKQEKGLANKLKALVYAKDRAGELLWNIITPTLLYSAKLYKEIADDIVAIDQAMKWGFGWEQGPFE
IWDAIGVEKSVQKMEENGKVVPAWVKEMLQNGFATFYKHDSGESYYYDNGEYKRIERNKKAISLKQLKEKHGVIKKNSGA
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKSF
QDAMMKIKYCSKPVVAAPYGMTLGGGTEVCLPTASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMAKGVEFDLQ
KVANKVFETIAMAKVSTSGQEAISHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKPPIRKKVPVVGETGYATLVLGA
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDIEREAFMSLISEMKSQARMQHMLVKGKPLRN

Sequences:

>Translated_793_residues
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPRALTKEEEAKGLTLEHKSVRNRFSNGALQKLVKQKPAPLAVKD
NLALITTGNLEDDLERLAEVDWIIEVVVENLDIKKQLFEKVDAVRKLGTIVSSNTSGISVEKMAEGRSDDFKKHFLGTHF
FNPPRYLKLLEIIPTNDTDPQVLNFMKQFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLREMMERGYSVGEVDSVTGP
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEEERDVFKVPTFMHEMLDRKWLGSKTGQGFFLKKGKEILELNPKTME
YEERKKLKAASVELSKQEKGLANKLKALVYAKDRAGELLWNIITPTLLYSAKLYKEIADDIVAIDQAMKWGFGWEQGPFE
IWDAIGVEKSVQKMEENGKVVPAWVKEMLQNGFATFYKHDSGESYYYDNGEYKRIERNKKAISLKQLKEKHGVIKKNSGA
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKSF
QDAMMKIKYCSKPVVAAPYGMTLGGGTEVCLPTASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMAKGVEFDLQ
KVANKVFETIAMAKVSTSGQEAISHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKPPIRKKVPVVGETGYATLVLGA
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDIEREAFMSLISEMKSQARMQHMLVKGKPLRN
>Mature_793_residues
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPRALTKEEEAKGLTLEHKSVRNRFSNGALQKLVKQKPAPLAVKD
NLALITTGNLEDDLERLAEVDWIIEVVVENLDIKKQLFEKVDAVRKLGTIVSSNTSGISVEKMAEGRSDDFKKHFLGTHF
FNPPRYLKLLEIIPTNDTDPQVLNFMKQFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLREMMERGYSVGEVDSVTGP
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEEERDVFKVPTFMHEMLDRKWLGSKTGQGFFLKKGKEILELNPKTME
YEERKKLKAASVELSKQEKGLANKLKALVYAKDRAGELLWNIITPTLLYSAKLYKEIADDIVAIDQAMKWGFGWEQGPFE
IWDAIGVEKSVQKMEENGKVVPAWVKEMLQNGFATFYKHDSGESYYYDNGEYKRIERNKKAISLKQLKEKHGVIKKNSGA
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAMILMEAQDDNYFEIEWVVKSF
QDAMMKIKYCSKPVVAAPYGMTLGGGTEVCLPTASIQASSETYMGLVEVGVGLIPGGGGNKELYIKHLNKMAKGVEFDLQ
KVANKVFETIAMAKVSTSGQEAISHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKPPIRKKVPVVGETGYATLVLGA
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDIEREAFMSLISEMKSQARMQHMLVKGKPLRN

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Mitochondria or Peroxisomes [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyacyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI296179429, Length=308, Percent_Identity=31.4935064935065, Blast_Score=116, Evalue=8e-26,
Organism=Homo sapiens, GI296179427, Length=325, Percent_Identity=29.8461538461538, Blast_Score=109, Evalue=1e-23,
Organism=Homo sapiens, GI20127408, Length=307, Percent_Identity=28.6644951140065, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI261878539, Length=257, Percent_Identity=28.4046692607004, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI68989263, Length=257, Percent_Identity=28.4046692607004, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI115430219, Length=229, Percent_Identity=26.6375545851528, Blast_Score=70, Evalue=1e-11,
Organism=Escherichia coli, GI1787661, Length=306, Percent_Identity=28.7581699346405, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1790281, Length=456, Percent_Identity=25.8771929824561, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1788682, Length=294, Percent_Identity=27.5510204081633, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17553560, Length=308, Percent_Identity=31.4935064935065, Blast_Score=132, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI17549919, Length=303, Percent_Identity=30.6930693069307, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17563036, Length=302, Percent_Identity=30.4635761589404, Blast_Score=102, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17508951, Length=423, Percent_Identity=27.6595744680851, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17508953, Length=423, Percent_Identity=27.6595744680851, Blast_Score=100, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI71985923, Length=414, Percent_Identity=26.0869565217391, Blast_Score=99, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI25144276, Length=303, Percent_Identity=29.7029702970297, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17558304, Length=421, Percent_Identity=26.3657957244656, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI71985930, Length=421, Percent_Identity=23.0403800475059, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45549573, Length=275, Percent_Identity=28.3636363636364, Blast_Score=89, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24583077, Length=421, Percent_Identity=26.603325415677, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24583079, Length=421, Percent_Identity=26.603325415677, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19921000, Length=421, Percent_Identity=26.603325415677, Blast_Score=87, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =1.1.1.35 [H]

Molecular weight: Translated: 88048; Mature: 88048

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS00867 CPSASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPRALTKEEEAKGLTLEHKSVRNRF
CCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCEEEHHHHHHHH
SNGALQKLVKQKPAPLAVKDNLALITTGNLEDDLERLAEVDWIIEVVVENLDIKKQLFEK
CCHHHHHHHHCCCCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VDAVRKLGTIVSSNTSGISVEKMAEGRSDDFKKHFLGTHFFNPPRYLKLLEIIPTNDTDP
HHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHEEEEEEECCCCCCH
QVLNFMKQFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLREMMERGYSVGEVDSVTGP
HHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEEERDVFKVPTFMHEMLDRKWLGSKTG
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QGFFLKKGKEILELNPKTMEYEERKKLKAASVELSKQEKGLANKLKALVYAKDRAGELLW
CCEEECCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCHHHHHHH
NIITPTLLYSAKLYKEIADDIVAIDQAMKWGFGWEQGPFEIWDAIGVEKSVQKMEENGKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCE
VPAWVKEMLQNGFATFYKHDSGESYYYDNGEYKRIERNKKAISLKQLKEKHGVIKKNSGA
EHHHHHHHHHCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCC
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAM
CEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCEEE
ILMEAQDDNYFEIEWVVKSFQDAMMKIKYCSKPVVAAPYGMTLGGGTEVCLPTASIQASS
EEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEECCCCEEECCCCCEEEECCCCCCCC
ETYMGLVEVGVGLIPGGGGNKELYIKHLNKMAKGVEFDLQKVANKVFETIAMAKVSTSGQ
HHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHH
EAISHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKPPIRKKVPVVGETGYATLVLGA
HHHHHCCCCCCCCCEECCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECC
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDIEREAFMSLISEMKSQAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MQHMLVKGKPLRN
HHHHHHCCCCCCC
>Mature Secondary Structure
MFQIKKAAVLGSGVMGSGIAAHLANIGIPTLLLDIVPRALTKEEEAKGLTLEHKSVRNRF
CCCCCHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCEEEHHHHHHHH
SNGALQKLVKQKPAPLAVKDNLALITTGNLEDDLERLAEVDWIIEVVVENLDIKKQLFEK
CCHHHHHHHHCCCCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
VDAVRKLGTIVSSNTSGISVEKMAEGRSDDFKKHFLGTHFFNPPRYLKLLEIIPTNDTDP
HHHHHHHHHHHCCCCCCCCHHHHHCCCCHHHHHHHHHCCCCCCHHHEEEEEEECCCCCCH
QVLNFMKQFGEDVLGKGVVIAKDTPNFIGNRIGTYGLLVTLREMMERGYSVGEVDSVTGP
HHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LIGRPKSATFRTLDVVGLDTFVHVANNVYENVQEEERDVFKVPTFMHEMLDRKWLGSKTG
CCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QGFFLKKGKEILELNPKTMEYEERKKLKAASVELSKQEKGLANKLKALVYAKDRAGELLW
CCEEECCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEECCHHHHHHH
NIITPTLLYSAKLYKEIADDIVAIDQAMKWGFGWEQGPFEIWDAIGVEKSVQKMEENGKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCHHHHHHHHHHCCCE
VPAWVKEMLQNGFATFYKHDSGESYYYDNGEYKRIERNKKAISLKQLKEKHGVIKKNSGA
EHHHHHHHHHCCCEEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCCCEECCCCC
SLIDLGDGILCLEFHSKSNAIGMDITQMINYAVDEVEKNYKGLVIGNQSKNFCVGANLAM
CEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCEEE
ILMEAQDDNYFEIEWVVKSFQDAMMKIKYCSKPVVAAPYGMTLGGGTEVCLPTASIQASS
EEEECCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEECCCCEEECCCCCEEEECCCCCCCC
ETYMGLVEVGVGLIPGGGGNKELYIKHLNKMAKGVEFDLQKVANKVFETIAMAKVSTSGQ
HHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHH
EAISHNFLGDKDGISVNGDHLLYDAKQKALALYEAGYKPPIRKKVPVVGETGYATLVLGA
HHHHHCCCCCCCCCEECCCEEEEHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEECC
EAMHLSGYISEYDLHIAKKLAYVIAGGKVPYGTEVDEQYLLDIEREAFMSLISEMKSQAR
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MQHMLVKGKPLRN
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]