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The map label for this gene is uvrC [H]

Identifier: 152976918

GI number: 152976918

Start: 3285775

End: 3287565

Strand: Reverse

Name: uvrC [H]

Synonym: Bcer98_3219

Alternate gene names: 152976918

Gene position: 3287565-3285775 (Counterclockwise)

Preceding gene: 152976919

Following gene: 152976916

Centisome position: 80.44

GC content: 36.57

Gene sequence:

>1791_bases
ATGAGAGTGCACGAACATTTAAAAGAGAAGTTAGCAATTTTACCAGACCAACCAGGTTGTTATTTGATGAAGGATAAGCA
GGGAACGGTCATATATGTCGGAAAGGCGAAAGTATTAAAAAATCGTGTGCGCTCGTATTTTACCGGTTCACATGATGGGA
AGACACTTCGTCTTGTTGGAGAGATTGCTGACTTTGAATACATTGTGACTTCTTCCAATTTAGAAGCACTTATTTTAGAA
TTAAATTTAATTAAAAAGTATGATCCGCGCTATAATATGAAATTAAAAGATGATAAAACATATCCGTTTATTAAAATTAC
TGGAGAGAAGCAGCCGCGTTTGCTAATTACGCGAAAGGTGAAAAAAGACAAAGGAAAGTATTTTGGTCCTTATCCAAACT
CACAGTCTGCACATGAAACGAAAAAATTACTAGATCGTATGTATCCGCTTCGTAAATGTACAAAAATGCCGGACAAAGTA
TGCTTATATTATCATATGGGGCAATGTCTAGCGCCTTGTGTAAACGAAGTAACAGATGAACAAAATAAAGAAATCGTTGA
TAAAATTACAAAATTTTTAAATGGTGGGCATAAAGAAATTCGTTCAGAATTAGAAGCGAAAATGTATGAGGCATCTGAGA
AATTGGAATTTGAACGGGCGAAAGAACTGCGCGATCAAATTGCTCATATGGATGCAATTATGGAAAAGCAAAAGATGATT
ATGAATGATATTGTAGATCGTGATGTATTTGGATATGCAGTAGATAAAGGGTGGATGTGCGTGCAAGTCTTCTTCATTCG
AAAAGGGAAGTTGATTGAGCGCGACGTTTCTATGTTTCCGATTTATGATGAACCAGAGGAAGGGTTCCTAACATTTATTG
GCCAATTTTATGAGCAAAACAATCATTTTAAACCGAAAGAAATCGCCGTGCCAGGAAGTATTGATCCTGAATTAGTAGAG
CGTTTTTTAGAAGTGGATGTAACGCAACCAAAGCGTGGGAAGAAAAAAGAACTTGTTGAACTGGCAAATAAAAATGCGAA
AATTGCTTTAGAAGAGAAGTTTTATTTAATTGAACGTGATGAAGAGCGTACAGTAAAAGCAATTGAAAATTTAGGAGAAC
GGTTAGGAATTGACACACCGTATCGGATTGAGGCCTTTGATAACTCAAATATTCAAGGAGTAAATCCTGTATCGGCAATG
ATTGTATTTATTGATGGAAAGCCTGCGAAAAAGGAATATCGTAAATATAAAATCAAAACGGTTCAAGGCCCTGATGATTA
TGAATCGATGCGAGAAGTTGTGCGTCGCCGCTATACAAGAGCATTAAAAGAAGGATTACCGCTTCCTGATTTAATTGTTA
TTGATGGCGGGAAAGGGCATCTTGCGGCGGCAAGTGATGTTTTAGAAAATGAGCTTGGATTATATATTCCGATAGCTGGA
CTTGTAAAAGATGAGAAGCACCGAACATCTCATTTAATCATCGGAGATCCACCAGATCCTGTTATACTAGAAAGAAATAG
TCAAGAATTTTATTTATTACAACGAATTCAAGATGAGGTACATCGATTTGCGATTACATTCCATCGGCAGCTGCATGGAA
AGTCAGTTATTCAATCTGCTTTAGATGGAATTCCAGGAGTGGGAGAAAAGAGAAAAAAAGTATTGTTAAAGCATTTTGGT
TCCTTGAAAAAAATGAAGGAAGCTTCTGTAGGGGAATTTGTTGAAGCGGGAATACCGCAACATGTAGCAGAAACCATTTA
TTCTTATTTAACGAACAACAAGACATTGTAG

Upstream 100 bases:

>100_bases
CTTTTTTCTTATTTTCCGTTACAATGAAAGAACGTATGTTGGGGAGTGACAGAGATGTTCCTCTTTATAAATAGCGATGA
TACATATGGAGAATGGAGGT

Downstream 100 bases:

>100_bases
TTTACAATGTCTTCTGTTTTTTGTTATAATCACGCAATATTCTAAAATATGTGAATAACGTGTAAGATATAAAACAGTCA
ACTAAACATATGTGTCTAGC

Product: excinuclease ABC subunit C

Products: NA

Alternate protein names: Protein uvrC; Excinuclease ABC subunit C [H]

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MRVHEHLKEKLAILPDQPGCYLMKDKQGTVIYVGKAKVLKNRVRSYFTGSHDGKTLRLVGEIADFEYIVTSSNLEALILE
LNLIKKYDPRYNMKLKDDKTYPFIKITGEKQPRLLITRKVKKDKGKYFGPYPNSQSAHETKKLLDRMYPLRKCTKMPDKV
CLYYHMGQCLAPCVNEVTDEQNKEIVDKITKFLNGGHKEIRSELEAKMYEASEKLEFERAKELRDQIAHMDAIMEKQKMI
MNDIVDRDVFGYAVDKGWMCVQVFFIRKGKLIERDVSMFPIYDEPEEGFLTFIGQFYEQNNHFKPKEIAVPGSIDPELVE
RFLEVDVTQPKRGKKKELVELANKNAKIALEEKFYLIERDEERTVKAIENLGERLGIDTPYRIEAFDNSNIQGVNPVSAM
IVFIDGKPAKKEYRKYKIKTVQGPDDYESMREVVRRRYTRALKEGLPLPDLIVIDGGKGHLAAASDVLENELGLYIPIAG
LVKDEKHRTSHLIIGDPPDPVILERNSQEFYLLQRIQDEVHRFAITFHRQLHGKSVIQSALDGIPGVGEKRKKVLLKHFG
SLKKMKEASVGEFVEAGIPQHVAETIYSYLTNNKTL

Sequences:

>Translated_596_residues
MRVHEHLKEKLAILPDQPGCYLMKDKQGTVIYVGKAKVLKNRVRSYFTGSHDGKTLRLVGEIADFEYIVTSSNLEALILE
LNLIKKYDPRYNMKLKDDKTYPFIKITGEKQPRLLITRKVKKDKGKYFGPYPNSQSAHETKKLLDRMYPLRKCTKMPDKV
CLYYHMGQCLAPCVNEVTDEQNKEIVDKITKFLNGGHKEIRSELEAKMYEASEKLEFERAKELRDQIAHMDAIMEKQKMI
MNDIVDRDVFGYAVDKGWMCVQVFFIRKGKLIERDVSMFPIYDEPEEGFLTFIGQFYEQNNHFKPKEIAVPGSIDPELVE
RFLEVDVTQPKRGKKKELVELANKNAKIALEEKFYLIERDEERTVKAIENLGERLGIDTPYRIEAFDNSNIQGVNPVSAM
IVFIDGKPAKKEYRKYKIKTVQGPDDYESMREVVRRRYTRALKEGLPLPDLIVIDGGKGHLAAASDVLENELGLYIPIAG
LVKDEKHRTSHLIIGDPPDPVILERNSQEFYLLQRIQDEVHRFAITFHRQLHGKSVIQSALDGIPGVGEKRKKVLLKHFG
SLKKMKEASVGEFVEAGIPQHVAETIYSYLTNNKTL
>Mature_596_residues
MRVHEHLKEKLAILPDQPGCYLMKDKQGTVIYVGKAKVLKNRVRSYFTGSHDGKTLRLVGEIADFEYIVTSSNLEALILE
LNLIKKYDPRYNMKLKDDKTYPFIKITGEKQPRLLITRKVKKDKGKYFGPYPNSQSAHETKKLLDRMYPLRKCTKMPDKV
CLYYHMGQCLAPCVNEVTDEQNKEIVDKITKFLNGGHKEIRSELEAKMYEASEKLEFERAKELRDQIAHMDAIMEKQKMI
MNDIVDRDVFGYAVDKGWMCVQVFFIRKGKLIERDVSMFPIYDEPEEGFLTFIGQFYEQNNHFKPKEIAVPGSIDPELVE
RFLEVDVTQPKRGKKKELVELANKNAKIALEEKFYLIERDEERTVKAIENLGERLGIDTPYRIEAFDNSNIQGVNPVSAM
IVFIDGKPAKKEYRKYKIKTVQGPDDYESMREVVRRRYTRALKEGLPLPDLIVIDGGKGHLAAASDVLENELGLYIPIAG
LVKDEKHRTSHLIIGDPPDPVILERNSQEFYLLQRIQDEVHRFAITFHRQLHGKSVIQSALDGIPGVGEKRKKVLLKHFG
SLKKMKEASVGEFVEAGIPQHVAETIYSYLTNNKTL

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision [H]

COG id: COG0322

COG function: function code L; Nuclease subunit of the excinuclease complex

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Escherichia coli, GI87081999, Length=614, Percent_Identity=37.9478827361564, Blast_Score=359, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003583
- InterPro:   IPR010994
- InterPro:   IPR001943
- InterPro:   IPR009055
- InterPro:   IPR004791
- InterPro:   IPR001162
- InterPro:   IPR000305 [H]

Pfam domain/function: PF01541 GIY-YIG; PF02151 UVR; PF08459 UvrC_HhH_N [H]

EC number: NA

Molecular weight: Translated: 68660; Mature: 68660

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: PS50151 UVR ; PS50164 UVRC_1 ; PS50165 UVRC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVHEHLKEKLAILPDQPGCYLMKDKQGTVIYVGKAKVLKNRVRSYFTGSHDGKTLRLVG
CCHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHCCCCCCCEEEEEE
EIADFEYIVTSSNLEALILELNLIKKYDPRYNMKLKDDKTYPFIKITGEKQPRLLITRKV
HHCCCEEEEECCCCEEEEEEHHHHHHCCCCCCCEECCCCCCCEEEEECCCCCCEEEEEHH
KKDKGKYFGPYPNSQSAHETKKLLDRMYPLRKCTKMPDKVCLYYHMGQCLAPCVNEVTDE
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCC
QNKEIVDKITKFLNGGHKEIRSELEAKMYEASEKLEFERAKELRDQIAHMDAIMEKQKMI
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNDIVDRDVFGYAVDKGWMCVQVFFIRKGKLIERDVSMFPIYDEPEEGFLTFIGQFYEQN
HHHHHHCCHHHHEECCCCEEEEEEEHHCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHCC
NHFKPKEIAVPGSIDPELVERFLEVDVTQPKRGKKKELVELANKNAKIALEEKFYLIERD
CCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEECEEEEEECC
EERTVKAIENLGERLGIDTPYRIEAFDNSNIQGVNPVSAMIVFIDGKPAKKEYRKYKIKT
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHEEEEE
VQGPDDYESMREVVRRRYTRALKEGLPLPDLIVIDGGKGHLAAASDVLENELGLYIPIAG
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEHH
LVKDEKHRTSHLIIGDPPDPVILERNSQEFYLLQRIQDEVHRFAITFHRQLHGKSVIQSA
HHCCCCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDGIPGVGEKRKKVLLKHFGSLKKMKEASVGEFVEAGIPQHVAETIYSYLTNNKTL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRVHEHLKEKLAILPDQPGCYLMKDKQGTVIYVGKAKVLKNRVRSYFTGSHDGKTLRLVG
CCHHHHHHHHHCCCCCCCCEEEEECCCCCEEEECCHHHHHHHHHHHHCCCCCCCEEEEEE
EIADFEYIVTSSNLEALILELNLIKKYDPRYNMKLKDDKTYPFIKITGEKQPRLLITRKV
HHCCCEEEEECCCCEEEEEEHHHHHHCCCCCCCEECCCCCCCEEEEECCCCCCEEEEEHH
KKDKGKYFGPYPNSQSAHETKKLLDRMYPLRKCTKMPDKVCLYYHMGQCLAPCVNEVTDE
HHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHHHCCC
QNKEIVDKITKFLNGGHKEIRSELEAKMYEASEKLEFERAKELRDQIAHMDAIMEKQKMI
CHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MNDIVDRDVFGYAVDKGWMCVQVFFIRKGKLIERDVSMFPIYDEPEEGFLTFIGQFYEQN
HHHHHHCCHHHHEECCCCEEEEEEEHHCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHCC
NHFKPKEIAVPGSIDPELVERFLEVDVTQPKRGKKKELVELANKNAKIALEEKFYLIERD
CCCCCCEEECCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCEEEEECEEEEEECC
EERTVKAIENLGERLGIDTPYRIEAFDNSNIQGVNPVSAMIVFIDGKPAKKEYRKYKIKT
HHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEECCCCCHHHHHHEEEEE
VQGPDDYESMREVVRRRYTRALKEGLPLPDLIVIDGGKGHLAAASDVLENELGLYIPIAG
ECCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHCCCCEEEEEHH
LVKDEKHRTSHLIIGDPPDPVILERNSQEFYLLQRIQDEVHRFAITFHRQLHGKSVIQSA
HHCCCCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDGIPGVGEKRKKVLLKHFGSLKKMKEASVGEFVEAGIPQHVAETIYSYLTNNKTL
HCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA